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Search results 1 to 100 out of 161 for Rpgrip1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
57096 | RPGRIP1
Type: gene
Organism: human
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Gene
100497908 | rpgrip1
Type: gene
Organism: frog, western clawed
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Gene
305850 | Rpgrip1
Type: gene
Organism: rat
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Gene
475400 | RPGRIP1
Type: gene
Organism: dog, domestic
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Gene
473331 | RPGRIP1
Type: gene
Organism: chimpanzee
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Gene
282656 | RPGRIP1
Type: gene
Organism: cattle
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Gene
568018 | rpgrip1
Type: gene
Organism: zebrafish
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Gene
707961 | RPGRIP1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1932134 | Rpgrip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR031134 | RPGRIP1
Type: Family
Description: Retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGRIP1) specifically interacts with retinitis pigmentosa GTPase regulator (RPGR) []. Mutations in RPGR cause X-linked retinitis pigmentosa type 3 (RP3), whereas mutations in RPGRIP1 cause Leber congenital amaurosis (LCA) []. RPGRIP1 is expressed in the retina and is present in the connecting cilium and outer segments of photoreceptors, where it partially co-localises with RPGR [, ]. RPGR isoforms seem to determine the subcellular targeting of RPGRIP1 [].
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Protein
Q0VGR8
Organism: Mus musculus/domesticus
Length: 1126  
Fragment?: false
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Gene
23322 | RPGRIP1L
Type: gene
Organism: human
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Publication
12651948 | J:82755
First Author: Zhao Y
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis.
Volume: 100
Issue: 7
Pages: 3965-70
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Publication
23213406 | -
First Author: Patil H
Year: 2012
Journal: Biol Open
Title: Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms.
Volume: 1
Issue: 2
Pages: 140-60
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Protein
M0QW56
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: true
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Protein
M0QWI1
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: true
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Protein
M0QWC0
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: false
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Protein
Q5D222
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Publication
19679561 | J:153721
First Author: Won J
Year: 2009
Journal: Hum Mol Genet
Title: RPGRIP1 is essential for normal rod photoreceptor outer segment elaboration and morphogenesis.
Volume: 18
Issue: 22
Pages: 4329-39
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Publication
15914599 | J:99415
First Author: Lu X
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Identification of novel murine- and human-specific RPGRIP1 splice variants with distinct expression profiles and subcellular localization.
Volume: 46
Issue: 6
Pages: 1882-90
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Publication
15772089 | J:99279
First Author: Shu X
Year: 2005
Journal: Hum Mol Genet
Title: RPGR ORF15 isoform co-localizes with RPGRIP1 at centrioles and basal bodies and interacts with nucleophosmin.
Volume: 14
Issue: 9
Pages: 1183-97
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Publication
25398945 | J:216279
First Author: Eblimit A
Year: 2015
Journal: Hum Mol Genet
Title: Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina.
Volume: 24
Issue: 6
Pages: 1584-601
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Protein
M0QWT5
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
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Protein
M0QWM1
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: true
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Protein
M0QW58
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: true
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Protein
M0QWL3
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
E9QQ97
Organism: Mus musculus/domesticus
Length: 1127  
Fragment?: false
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Protein
Q9EPQ2
Organism: Mus musculus/domesticus
Length: 1331  
Fragment?: false
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Protein
E7CHD7
Organism: Mus musculus/domesticus
Length: 1320  
Fragment?: false
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Publication
10958648 | -
First Author: Roepman R
Year: 2000
Journal: Hum Mol Genet
Title: The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors.
Volume: 9
Issue: 14
Pages: 2095-105
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Publication
25414380 | -
 
First Author: Li T
Year: 2014
Journal: Cold Spring Harb Perspect Med
Title: Leber congenital amaurosis caused by mutations in RPGRIP1.
Volume: 5
Issue: 4
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Gene
487278 | RPGRIP1L
Type: gene
Organism: dog, domestic
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Gene
454089 | RPGRIP1L
Type: gene
Organism: chimpanzee
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Gene
518659 | RPGRIP1L
Type: gene
Organism: cattle
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Gene
425392 | RPGRIP1L
Type: gene
Organism: chicken
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Gene
557688 | rpgrip1l
Type: gene
Organism: zebrafish
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Gene
697345 | RPGRIP1L
Type: gene
Organism: macaque, rhesus
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Publication
21685204 | -
First Author: Coene KL
Year: 2011
Journal: Hum Mol Genet
Title: The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase.
Volume: 20
Issue: 18
Pages: 3592-605
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Publication
22825473 | J:315239
 
First Author: Patil H
Year: 2012
Journal: Cell Death Dis
Title: Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons.
Volume: 3
Pages: e355
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Protein Coding Gene
MGP_CAROLIEiJ_G0019235 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021291 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021248 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1932134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021691 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020999 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020604 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030257 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020127 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16123399 | J:101340
First Author: Pawlyk BS
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP.
Volume: 46
Issue: 9
Pages: 3039-45
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GXD Expression
GXD Expression
     
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716820
Stage: TS20
Assay Id: MGI:3585596
Age: embryonic day 12.0
Specimen Label: E12
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:3585596
Age: embryonic day 14.0
Image: E14
Specimen Label: E14
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716824
Stage: TS24
Assay Id: MGI:3585596
Age: embryonic day 16.0
Image: E16
Specimen Label: E16
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716826
Stage: TS26
Assay Id: MGI:3585596
Age: embryonic day 18.0
Image: E18
Specimen Label: E18
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:3585596
Age: postnatal day 0-1
Image: P0/1
Specimen Label: P0/1
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:3585596
Age: postnatal day 2-3
Image: P2/3
Specimen Label: P2/3
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:4417378
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4940846
Age: embryonic day 14.5
Specimen Label: Table 3 G14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4885951
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:4941036
Age: embryonic day 15.5
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647028
Stage: TS28
Assay Id: MGI:3585596
Age: postnatal day 6
Specimen Label: CNS
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:3585596
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585596
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the scleral outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585596
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585596
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:3574829
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585596
Age: postnatal adult
Image: Adult
Note: Expression was detected in the inner segment.
Specimen Label: Adult
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3834405
Assay Type: RNA in situ
Annotation Date: 2009-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3834677
Age: postnatal adult
Image: S6 wt
Note: Expression was detected in rods.
Specimen Label: S6 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3834405
Assay Type: RNA in situ
Annotation Date: 2009-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3834677
Age: postnatal adult
Image: S6 Nr2e3-/-
Note: Expression was detected in rods as in wild type.
Specimen Label: S6 Nr2e3-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4417378
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4940846
Age: embryonic day 14.5
Note: Expression is in the ventricular zone and is absent in the subventricular zone.
Specimen Label: Table 3 G14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4885951
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691323
Stage: TS23
Assay Id: MGI:4941036
Age: embryonic day 15.5
Note: Absent in the ventricular and subventricular zones.
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4417378
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691122
Stage: TS22
Assay Id: MGI:4940846
Age: embryonic day 14.5
Specimen Label: Table 3 G14.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4885951
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691123
Stage: TS23
Assay Id: MGI:4941036
Age: embryonic day 15.5
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5751146
Assay Type: Immunohistochemistry
Annotation Date: 2016-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5751147
Age: postnatal day 12
Image: 1C Ahi1+/+
Note: Expression is in the transition zone of the photoreceptor sensory epithelium.
Specimen Label: 1C Ahi1+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4417378
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4940846
Age: embryonic day 14.5
Specimen Label: Table 3 G14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4885951
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:4941036
Age: embryonic day 15.5
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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Publication
- | J:68097
   
First Author: Hong D
Year: 2000
Journal: GenBank Submission
Title: Mus musculus RPGR-interacting protein mRNA, complete cds
Pages: AY008297
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Publication
11104772 | J:68848
First Author: Hong DH
Year: 2001
Journal: J Biol Chem
Title: Retinitis pigmentosa GTPase regulator (RPGRr)-interacting protein is stably associated with the photoreceptor ciliary axoneme and anchors RPGR to the connecting cilium.
Volume: 276
Issue: 15
Pages: 12091-9
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Publication
27162334 | J:232177
First Author: Sun X
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.
Volume: 113
Issue: 21
Pages: E2925-34
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Publication
22323458 | J:196243
First Author: Wright RN
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: RpgrORF15 connects to the usher protein network through direct interactions with multiple whirlin isoforms.
Volume: 53
Issue: 3
Pages: 1519-29
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Publication
26747773 | J:231018
First Author: Kooragayala K
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Quantification of Oxygen Consumption in Retina Ex Vivo Demonstrates Limited Reserve Capacity of Photoreceptor Mitochondria.
Volume: 56
Issue: 13
Pages: 8428-36
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Publication
27064284 | J:234938
First Author: Stratigopoulos G
Year: 2016
Journal: J Clin Invest
Title: Hypomorphism of Fto and Rpgrip1l causes obesity in mice.
Volume: 126
Issue: 5
Pages: 1897-910
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Publication
26139610 | J:233541
First Author: Zhao L
Year: 2015
Journal: EMBO Mol Med
Title: Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration.
Volume: 7
Issue: 9
Pages: 1179-97
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Publication
26936822 | J:235807
First Author: Rao KN
Year: 2016
Journal: Hum Mol Genet
Title: Ciliopathy-associated protein CEP290 modifies the severity of retinal degeneration due to loss of RPGR.
Volume: 25
Issue: 10
Pages: 2005-2012
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Publication
28859131 | J:243745
First Author: Krebs MP
Year: 2017
Journal: PLoS One
Title: Mouse models of human ocular disease for translational research.
Volume: 12
Issue: 8
Pages: e0183837
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Publication
29899041 | J:264617
First Author: Dharmat R
Year: 2018
Journal: J Cell Biol
Title: SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.
Volume: 217
Issue: 8
Pages: 2851-2865
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Publication
20592197 | J:161846
First Author: Westfall JE
Year: 2010
Journal: J Neurosci
Title: Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1.
Volume: 30
Issue: 26
Pages: 8759-68
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Publication
18297065 | J:135664
First Author: Han YG
Year: 2008
Journal: Nat Neurosci
Title: Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells.
Volume: 11
Issue: 3
Pages: 277-84
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Publication
18256137 | J:133509
First Author: Stratigopoulos G
Year: 2008
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Regulation of Fto/Ftm gene expression in mice and humans.
Volume: 294
Issue: 4
Pages: R1185-96
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Publication
- | J:82238
     
First Author: JAX Neuroscience Mutagenesis Facility
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from JAX NMF ENU Mutagenesis Program
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Publication
21052544 | J:166679
 
First Author: Won J
Year: 2011
Journal: J Ophthalmol
Title: Mouse model resources for vision research.
Volume: 2011
Pages: 391384
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Publication
27534441 | J:234901
 
First Author: Potter PK
Year: 2016
Journal: Nat Commun
Title: Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Volume: 7
Pages: 12444
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Publication
21779340 | J:175792
First Author: Jelcick AS
Year: 2011
Journal: PLoS One
Title: Genetic variations strongly influence phenotypic outcome in the mouse retina.
Volume: 6
Issue: 7
Pages: e21858
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Publication
19884258 | J:154029
First Author: Munger SC
Year: 2009
Journal: Genes Dev
Title: Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.
Volume: 23
Issue: 21
Pages: 2521-36
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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