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Search results 1 to 100 out of 106 for Rph3a

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Hits by Strain

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Type Details Score
Gene
22895 | RPH3A
Type: gene
Organism: human
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Gene
738818 | RPH3A
Type: gene
Organism: chimpanzee
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Gene
416886 | RPH3A
Type: gene
Organism: chicken
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Gene
712197 | RPH3A
Type: gene
Organism: macaque, rhesus
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Gene
100487950 | rph3a
Type: gene
Organism: frog, western clawed
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Gene
282044 | RPH3A
Type: gene
Organism: cattle
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Gene
171039 | Rph3a
Type: gene
Organism: rat
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Gene
611038 | RPH3A
Type: gene
Organism: dog, domestic
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Protein Domain
IPR028698 | RPH3A
Type: Family
Description: In humans, Rabphilin-3A (RPH3A) contains two C2 domains and one RabBD (Rab-binding) domain. RPH3A may interact with the SNARE complex and regulate synaptic vesicle exocytosis and Ca2+-triggered neurotransmitter release []. It has been linked to neurodegenerative diseases, such as Huntington's disease [], Lewy body disease []and Alzheimer's disease [].
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Protein Coding Gene
MGI:102788 | Rph3a
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:3639882
Assay Type: RNA in situ
Annotation Date: 2006-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3639926
Age: embryonic day 14.5
Note: Expression was detected in the inferior olivary nucleus (ION).
Specimen Label: 6P Rph3a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3639882
Assay Type: RNA in situ
Annotation Date: 2006-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3639926
Age: embryonic day 14.5
Note: Expression was detected in the inferior olivary nucleus (ION) as in wild type, but the area of the ION was increased.
Specimen Label: 6P Rph3a
Detected: true
Specimen Num: 2
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Publication
28636945 | J:254711
First Author: Yuan Q
Year: 2017
Journal: Cell Rep
Title: PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury.
Volume: 19
Issue: 12
Pages: 2586-2597
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Publication
17877635 | -
First Author: Smith R
Year: 2007
Journal: J Neurochem
Title: Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.
Volume: 103
Issue: 1
Pages: 115-23
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Publication
15207266 | -
First Author: Dalfó E
Year: 2004
Journal: Neurobiol Dis
Title: Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.
Volume: 16
Issue: 1
Pages: 92-7
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Publication
24200817 | -
 
First Author: Tan MG
Year: 2014
Journal: Neurochem Int
Title: Decreased rabphilin 3A immunoreactivity in Alzheimer's disease is associated with Aβ burden.
Volume: 64
Pages: 29-36
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Protein
A0A0J9YV12
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: true
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Protein
P47708
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Protein
Q768S5
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Publication
26679993 | J:228276
 
First Author: Stanic J
Year: 2015
Journal: Nat Commun
Title: Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Volume: 6
Pages: 10181
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Protein Coding Gene
MGP_CAROLIEiJ_G0027676 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_102788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029123 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024256 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028674 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4884891
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944986
Age: embryonic day 11.5
Image: g00427 E11.5
Specimen Label: g00427 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4884891
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944986
Age: embryonic day 11.5
Image: g00427 E11.5
Specimen Label: g00427 E11.5
Detected: true
Specimen Num: 1
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Publication
7822236 | J:20188
First Author: Inagaki N
Year: 1994
Journal: J Biochem
Title: Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells.
Volume: 116
Issue: 2
Pages: 239-42
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Publication
10407024 | J:56293
First Author: Schlüter OM
Year: 1999
Journal: J Neurosci
Title: Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release.
Volume: 19
Issue: 14
Pages: 5834-46
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Publication
10025402 | J:52577
First Author: Ostermeier C
Year: 1999
Journal: Cell
Title: Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.
Volume: 96
Issue: 3
Pages: 363-74
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Publication
35398339 | J:325659
 
First Author: Sekine Y
Year: 2022
Journal: Exp Neurol
Title: Rabphilin3A reduces integrin-dependent growth cone signaling to restrict axon regeneration after trauma.
Volume: 353
Pages: 114070
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Publication
30930167 | J:284160
First Author: Ren C
Year: 2019
Journal: Dev Cell
Title: Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment.
Volume: 49
Issue: 2
Pages: 206-219.e7
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Publication
10707984 | J:60150
First Author: Fenster SD
Year: 2000
Journal: Neuron
Title: Piccolo, a presynaptic zinc finger protein structurally related to bassoon.
Volume: 25
Issue: 1
Pages: 203-14
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Publication
15967669 | J:104634
First Author: Smith R
Year: 2005
Journal: Neurobiol Dis
Title: Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction.
Volume: 20
Issue: 3
Pages: 673-84
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Publication
16763567 | J:326633
First Author: Deák F
Year: 2006
Journal: EMBO J
Title: Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion.
Volume: 25
Issue: 12
Pages: 2856-66
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Publication
16043482 | J:114721
First Author: Baldini G
Year: 2005
Journal: J Biol Chem
Title: Rabphilin localizes with the cell actin cytoskeleton and stimulates association of granules with F-actin cross-linked by {alpha}-actinin.
Volume: 280
Issue: 41
Pages: 34974-84
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Publication
22993210 | J:200268
First Author: Brozzi F
Year: 2012
Journal: Mol Biol Cell
Title: MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway.
Volume: 23
Issue: 22
Pages: 4444-55
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Publication
14722103 | J:166024
First Author: Fukuda M
Year: 2004
Journal: J Biol Chem
Title: Rabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cells.
Volume: 279
Issue: 13
Pages: 13065-75
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Publication
33753311 | J:317639
 
First Author: Bourgeois-Jaarsma Q
Year: 2021
Journal: Mol Cell Neurosci
Title: Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons.
Volume: 112
Pages: 103613
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Publication
31235931 | J:281603
First Author: Avagliano Trezza R
Year: 2019
Journal: Nat Neurosci
Title: Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.
Volume: 22
Issue: 8
Pages: 1235-1247
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Publication
21521611 | J:174823
First Author: Pang ZP
Year: 2011
Journal: Neuron
Title: Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.
Volume: 70
Issue: 2
Pages: 244-51
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Publication
11773082 | J:75312
First Author: Kuroda TS
Year: 2002
Journal: J Biol Chem
Title: The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
Volume: 277
Issue: 11
Pages: 9212-8
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Publication
11056535 | J:71886
First Author: Ozaki N
Year: 2000
Journal: Nat Cell Biol
Title: cAMP-GEFII is a direct target of cAMP in regulated exocytosis.
Volume: 2
Issue: 11
Pages: 805-11
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Publication
11359932 | J:126869
First Author: Tanaka M
Year: 2001
Journal: Mol Biol Cell
Title: Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction.
Volume: 12
Issue: 5
Pages: 1421-30
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Publication
14559211 | J:86115
First Author: Mashimo T
Year: 2003
Journal: Genomics
Title: Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2',5'-oligoadenylate synthetases.
Volume: 82
Issue: 5
Pages: 537-52
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Publication
12578829 | J:83108
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.
Volume: 278
Issue: 17
Pages: 15373-80
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Publication
12590134 | J:83162
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
Volume: 278
Issue: 17
Pages: 15390-6
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Publication
17803915 | J:127941
First Author: Yao I
Year: 2007
Journal: Cell
Title: SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.
Volume: 130
Issue: 5
Pages: 943-57
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Publication
12080145 | J:77001
First Author: Perelygin AA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Positional cloning of the murine flavivirus resistance gene.
Volume: 99
Issue: 14
Pages: 9322-7
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Publication
18829970 | J:143462
First Author: Liu Z
Year: 2008
Journal: J Neurosci
Title: Control of precerebellar neuron development by Olig3 bHLH transcription factor.
Volume: 28
Issue: 40
Pages: 10124-33
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Publication
31869353 | J:283382
First Author: Qin L
Year: 2019
Journal: PLoS One
Title: Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip.
Volume: 14
Issue: 12
Pages: e0226602
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Publication
16364898 | J:107595
First Author: Landsberg RL
Year: 2005
Journal: Neuron
Title: Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6.
Volume: 48
Issue: 6
Pages: 933-47
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Publication
18987029 | J:143205
First Author: Kanadia RN
Year: 2008
Journal: Development
Title: Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.
Volume: 135
Issue: 23
Pages: 3923-33
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Publication
17124501 | J:119934
First Author: Schoch S
Year: 2006
Journal: EMBO J
Title: Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.
Volume: 25
Issue: 24
Pages: 5852-63
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Publication
29445148 | J:314661
First Author: Zhang Q
Year: 2018
Journal: Cell Death Dis
Title: Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.
Volume: 9
Issue: 2
Pages: 247
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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