Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:519185 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3564922 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3825909 |
Age: |
embryonic day 14.5 |
Image: |
Additional file 4 Rpl37a |
|
Specimen Label: |
Additional file 4 Rpl37a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:519185 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4354914 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Rpl37a |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:519185 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4354914 |
Age: |
embryonic day 14.5 |
|
Note: |
There is no expression in either the upper or lower cortical plate. |
Specimen Label: |
Table S5 - Rpl37a |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:519185 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4354914 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Rpl37a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Su Y |
Year: |
1993 |
Journal: |
Nucleic Acids Res |
Title: |
Primary sequence of the mouse ribosomal protein L37a. |
Volume: |
21 |
Issue: |
18 |
Pages: |
4400 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6690439 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6690465 |
Age: |
postnatal adult |
Image: |
S5 |
|
Specimen Label: |
Setd5+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6690439 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6690465 |
Age: |
postnatal adult |
Image: |
S5 |
|
Specimen Label: |
Setd5+/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7467111 |
Assay Type: |
Western blot |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1734021 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7467177 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Ctrl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7467111 |
Assay Type: |
Western blot |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1734021 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7467177 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Mut |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7467120 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1734021 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7467189 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Ctrl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7467120 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1734021 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7467189 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Mut |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa T |
Year: |
2020 |
Journal: |
iScience |
Title: |
The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression. |
Volume: |
23 |
Issue: |
4 |
Pages: |
101030 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao Q |
Year: |
2022 |
Journal: |
J Cell Sci |
Title: |
Drp1 regulates transcription of ribosomal protein genes in embryonic hearts. |
Volume: |
135 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li H |
Year: |
2022 |
Journal: |
Nature |
Title: |
A male germ-cell-specific ribosome controls male fertility. |
Volume: |
612 |
Issue: |
7941 |
Pages: |
725-731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Distler U |
Year: |
2014 |
Journal: |
Proteomics |
Title: |
In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. |
Volume: |
14 |
Issue: |
21-22 |
Pages: |
2607-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khatter H |
Year: |
2015 |
Journal: |
Nature |
Title: |
Structure of the human 80S ribosome. |
Volume: |
520 |
Issue: |
7549 |
Pages: |
640-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kondrashov N |
Year: |
2011 |
Journal: |
Cell |
Title: |
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. |
Volume: |
145 |
Issue: |
3 |
Pages: |
383-397 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kozak CA |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus. |
Volume: |
10 |
Issue: |
9 |
Pages: |
853-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
1998 |
Journal: |
Hum Mol Genet |
Title: |
Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. |
Volume: |
7 |
Issue: |
12 |
Pages: |
1967-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sansom SN |
Year: |
2009 |
Journal: |
PLoS Genet |
Title: |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. |
Volume: |
5 |
Issue: |
6 |
Pages: |
e1000511 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoffman BG |
Year: |
2008 |
Journal: |
Genome Biol |
Title: |
Identification of transcripts with enriched expression in the developing and adult pancreas. |
Volume: |
9 |
Issue: |
6 |
Pages: |
R99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
82
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Mikolajczyk J |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs. |
Volume: |
282 |
Issue: |
36 |
Pages: |
26217-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finkbeiner E |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1067-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Westman BJ |
Year: |
2010 |
Journal: |
Mol Cell |
Title: |
A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58. |
Volume: |
39 |
Issue: |
4 |
Pages: |
618-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Di Bacco A |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
The SUMO-specific protease SENP5 is required for cell division. |
Volume: |
26 |
Issue: |
12 |
Pages: |
4489-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zunino R |
Year: |
2007 |
Journal: |
J Cell Sci |
Title: |
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. |
Volume: |
120 |
Issue: |
Pt 7 |
Pages: |
1178-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zunino R |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis. |
Volume: |
284 |
Issue: |
26 |
Pages: |
17783-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim EY |
Year: |
2015 |
Journal: |
J Mol Cell Cardiol |
Title: |
SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy. |
Volume: |
78 |
|
Pages: |
154-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Federzoni EA |
Year: |
2015 |
Journal: |
Leuk Res Rep |
Title: |
Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells. |
Volume: |
4 |
Issue: |
1 |
Pages: |
32-5 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
SENP5 peptidase (sentrin-specific peptidase 5, MEROPS identifier C48.008) is a deSUMOylating peptidase localized predominantly to the nucleolus. SENP5 releases the tag proteins SUMO-2 and -3 from conjugates, preferentially acting as an isopeptidase rather than an endopeptidase []. Simultaneous depletion of SENP3 and SENP5 results in enhanced SUMOylation of proteins such as RPL37A and GNL2, which are involved in the processing of pre-rRNA [], PELP1 and LAS1L, which are involved in the release of mature ribosomal particles [], and Nop58, which is a component of small nucleolar ribonucleoprotein (snoRNP) and SUMOlyation is required for binding of Nop58 to snoRNA to maintain nucleolar retention []. SENP5 depletion also affects mitotic progression, and cells arrest at the G2/M transition []. SENP5 is also involved in mitochondrial fusion and fission, because SUMOylated dynamin-1-like protein (Drp1), which is a mitochondrial fission factor, is a target for SENP5 []. DeSUMOylation of Drp1 is a contributory factor to cardiomyopathy []. During the G2/M transition stage of mitosis, SENP5 transiently locates to the mitochondrion []. SENP5 is also required for neutrophil differentiation, and the SNP5 gene is repressed in clinical acute myeloid leukemia []. |
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Publication |
First Author: |
Haindl M |
Year: |
2008 |
Journal: |
EMBO Rep |
Title: |
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. |
Volume: |
9 |
Issue: |
3 |
Pages: |
273-9 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
749
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
607
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Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
210
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Fragment?: |
true |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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