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Search results 1 to 100 out of 557 for Rptor

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Serra N
Year: 2019
Journal: Biol Reprod
Title: The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice†.
Volume: 100
Issue: 2
Pages: 429-439
Gene
Type: gene
Organism: Homo sapiens
Publication    
First Author: Yang C
Year: 2018
Journal: Elife
Title: mTORC1 and mTORC2 differentially promote natural killer cell development.
Volume: 7
Publication
First Author: Tang F
Year: 2012
Journal: J Immunol
Title: A critical role for Rictor in T lymphopoiesis.
Volume: 189
Issue: 4
Pages: 1850-7
Publication
First Author: Wang S
Year: 2015
Journal: Mol Cell Biol
Title: Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
Volume: 35
Issue: 7
Pages: 1299-313
Publication
First Author: Morrison MM
Year: 2015
Journal: PLoS Genet
Title: mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
Volume: 11
Issue: 7
Pages: e1005291
Publication
First Author: Cho SH
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Volume: 116
Issue: 18
Pages: 8975-8984
Publication
First Author: Chimin P
Year: 2017
Journal: J Lipid Res
Title: Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.
Volume: 58
Issue: 9
Pages: 1797-1807
Publication
First Author: Sampson LL
Year: 2016
Journal: FASEB J
Title: mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice.
Volume: 30
Issue: 3
Pages: 1263-75
Publication  
First Author: Ma S
Year: 2015
Journal: Exp Eye Res
Title: Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival.
Volume: 135
Pages: 1-13
Publication
First Author: Alejandro EU
Year: 2017
Journal: Diabetes
Title: Overexpression of Kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not β-Cell Mass.
Volume: 66
Issue: 8
Pages: 2150-2162
Publication
First Author: Kellersch B
Year: 2013
Journal: Blood
Title: Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function.
Volume: 121
Issue: 2
Pages: 298-307
Publication
First Author: Bercury KK
Year: 2014
Journal: J Neurosci
Title: Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.
Volume: 34
Issue: 13
Pages: 4466-80
Publication
First Author: Limon JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.
Volume: 111
Issue: 47
Pages: E5076-85
Publication
First Author: Xu L
Year: 2017
Journal: Immunity
Title: The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells.
Volume: 47
Issue: 3
Pages: 538-551.e5
Publication
First Author: Yang K
Year: 2013
Journal: Immunity
Title: T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
Volume: 39
Issue: 6
Pages: 1043-56
Publication
First Author: Kalim KW
Year: 2017
Journal: PLoS One
Title: mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.
Volume: 12
Issue: 8
Pages: e0183266
Publication
First Author: Risson V
Year: 2009
Journal: J Cell Biol
Title: Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.
Volume: 187
Issue: 6
Pages: 859-74
Publication
First Author: Bentzinger CF
Year: 2008
Journal: Cell Metab
Title: Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy.
Volume: 8
Issue: 5
Pages: 411-24
Publication
First Author: Gödel M
Year: 2011
Journal: J Clin Invest
Title: Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
Volume: 121
Issue: 6
Pages: 2197-209
Publication
First Author: Romanino K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
Volume: 108
Issue: 51
Pages: 20808-13
Publication  
First Author: Hiraiwa M
Year: 2019
Journal: Front Pharmacol
Title: mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis.
Volume: 10
Pages: 684
Publication
First Author: Chen CJ
Year: 2019
Journal: Nat Med
Title: Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency.
Volume: 25
Issue: 11
Pages: 1684-1690
Publication
First Author: Moloughney JG
Year: 2016
Journal: Mol Cell
Title: mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1.
Volume: 63
Issue: 5
Pages: 811-26
Publication
First Author: Lebrun-Julien F
Year: 2014
Journal: J Neurosci
Title: Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.
Volume: 34
Issue: 25
Pages: 8432-48
Publication
First Author: Kalaitzidis D
Year: 2012
Journal: Cell Stem Cell
Title: mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.
Volume: 11
Issue: 3
Pages: 429-39
Publication
First Author: Wang F
Year: 2018
Journal: Nat Commun
Title: Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.
Volume: 9
Issue: 1
Pages: 4874
Publication
First Author: Karmaus PWF
Year: 2017
Journal: J Exp Med
Title: Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.
Volume: 214
Issue: 9
Pages: 2629-2647
Publication
First Author: Huang SC
Year: 2016
Journal: Immunity
Title: Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
Volume: 45
Issue: 4
Pages: 817-830
Publication  
First Author: Chen W
Year: 2016
Journal: eNeuro
Title: Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion.
Volume: 3
Issue: 6
Publication  
First Author: Yang M
Year: 2016
Journal: Nat Commun
Title: NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Volume: 7
Pages: 12730
Publication
First Author: Hertzler-Schaefer K
Year: 2014
Journal: Cell Rep
Title: Pten loss induces autocrine FGF signaling to promote skin tumorigenesis.
Volume: 6
Issue: 5
Pages: 818-26
Publication
First Author: Zeng H
Year: 2013
Journal: Nature
Title: mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Volume: 499
Issue: 7459
Pages: 485-90
Publication
First Author: Zeng H
Year: 2018
Journal: Sci Adv
Title: Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.
Volume: 4
Issue: 1
Pages: eaar5701
Publication
First Author: Le Bacquer O
Year: 2013
Journal: J Endocrinol
Title: mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Volume: 216
Issue: 1
Pages: 21-9
Publication
First Author: Malik N
Year: 2019
Journal: Sci Rep
Title: mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.
Volume: 9
Issue: 1
Pages: 16917
Publication
First Author: Cai Y
Year: 2019
Journal: Cell Rep
Title: Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation.
Volume: 27
Issue: 10
Pages: 3034-3048.e5
Publication
First Author: Lamming DW
Year: 2012
Journal: Science
Title: Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Volume: 335
Issue: 6076
Pages: 1638-43
Publication
First Author: Venkatesh A
Year: 2015
Journal: J Clin Invest
Title: Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.
Volume: 125
Issue: 4
Pages: 1446-58
Publication  
First Author: Miao L
Year: 2016
Journal: Elife
Title: mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system.
Volume: 5
Pages: e14908
Publication
First Author: Nie X
Year: 2018
Journal: PLoS Genet
Title: mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development.
Volume: 14
Issue: 7
Pages: e1007491
Publication
First Author: Guertin DA
Year: 2006
Journal: Dev Cell
Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Volume: 11
Issue: 6
Pages: 859-71
Publication
First Author: Hung CM
Year: 2014
Journal: Cell Rep
Title: Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Volume: 8
Issue: 1
Pages: 256-71
Publication
First Author: Nobs SP
Year: 2015
Journal: Immunity
Title: PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.
Volume: 43
Issue: 4
Pages: 674-89
Publication  
First Author: Rion N
Year: 2019
Journal: Development
Title: mTOR controls embryonic and adult myogenesis via mTORC1.
Volume: 146
Issue: 7
Publication
First Author: Guertin DA
Year: 2009
Journal: Cancer Cell
Title: mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Volume: 15
Issue: 2
Pages: 148-59
Publication
First Author: Grahammer F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.
Volume: 111
Issue: 27
Pages: E2817-26
Publication
First Author: Rosner M
Year: 2008
Journal: Hum Mol Genet
Title: Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.
Volume: 17
Issue: 19
Pages: 2934-48
Publication
First Author: Kogasaka Y
Year: 2013
Journal: Mol Reprod Dev
Title: Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in mice.
Volume: 80
Issue: 4
Pages: 334-48
Publication
First Author: Wu CC
Year: 2017
Journal: Dev Cell
Title: mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.
Volume: 43
Issue: 6
Pages: 673-688.e5
Publication  
First Author: Ding X
Year: 2016
Journal: Nat Commun
Title: mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation.
Volume: 7
Pages: 13226
Publication
First Author: Sinclair C
Year: 2017
Journal: Science
Title: mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation.
Volume: 357
Issue: 6355
Pages: 1014-1021
Publication
First Author: Mills JR
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 promotes survival through translational control of Mcl-1.
Volume: 105
Issue: 31
Pages: 10853-8
Publication
First Author: Robitaille AM
Year: 2013
Journal: Science
Title: Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis.
Volume: 339
Issue: 6125
Pages: 1320-3
Publication
First Author: Nie X
Year: 2020
Journal: Dev Biol
Title: mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.
Volume: 467
Issue: 1-2
Pages: 77-87
Publication
First Author: Sinagoga KL
Year: 2017
Journal: Development
Title: Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Volume: 144
Issue: 13
Pages: 2402-2414
Publication
First Author: Ikenoue T
Year: 2008
Journal: EMBO J
Title: Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.
Volume: 27
Issue: 14
Pages: 1919-31
Publication
First Author: Delgoffe GM
Year: 2009
Journal: Mol Immunol
Title: Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation.
Volume: 46
Issue: 13
Pages: 2694-8
Publication
First Author: Patursky-Polischuk I
Year: 2009
Journal: Mol Cell Biol
Title: The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner.
Volume: 29
Issue: 3
Pages: 640-9
Publication
First Author: Sureshbabu A
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.
Volume: 55
Issue: 5
Pages: 722-735
Publication  
First Author: Fitter S
Year: 2017
Journal: Mol Cell Biol
Title: mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation.
Volume: 37
Issue: 7
Publication
First Author: Gorre N
Year: 2014
Journal: PLoS One
Title: mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility.
Volume: 9
Issue: 10
Pages: e110491
Publication
First Author: Martin SK
Year: 2018
Journal: Sci Rep
Title: mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis.
Volume: 8
Issue: 1
Pages: 14501
Publication
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
Publication
First Author: Jacinto E
Year: 2004
Journal: Nat Cell Biol
Title: Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Volume: 6
Issue: 11
Pages: 1122-8
Publication
First Author: Oh WJ
Year: 2010
Journal: EMBO J
Title: mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Volume: 29
Issue: 23
Pages: 3939-51
Publication
First Author: Smithson LJ
Year: 2016
Journal: Genes Dev
Title: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Volume: 30
Issue: 12
Pages: 1383-8
Publication    
First Author: Tang F
Year: 2017
Journal: Elife
Title: A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice.
Volume: 6
Publication
First Author: Partovian C
Year: 2008
Journal: Mol Cell
Title: Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.
Volume: 32
Issue: 1
Pages: 140-9
Publication  
First Author: Jones I
Year: 2019
Journal: Biol Open
Title: Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction.
Volume: 8
Issue: 8
Publication
First Author: Lian WS
Year: 2018
Journal: Cell Death Dis
Title: Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR.
Volume: 9
Issue: 10
Pages: 938
Publication
First Author: Hasumi Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Volume: 106
Issue: 44
Pages: 18722-7
Publication
First Author: Sun IH
Year: 2018
Journal: J Immunol
Title: mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells.
Volume: 201
Issue: 2
Pages: 481-492
Publication
First Author: Asrani K
Year: 2019
Journal: J Clin Invest
Title: mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation.
Volume: 129
Issue: 12
Pages: 5584-5599
Publication
First Author: Cloëtta D
Year: 2013
Journal: J Neurosci
Title: Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis.
Volume: 33
Issue: 18
Pages: 7799-810
Publication  
First Author: Yamauchi T
Year: 2017
Journal: Mol Cell Biol
Title: FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
Volume: 37
Issue: 8
Publication
First Author: Magri L
Year: 2011
Journal: Cell Stem Cell
Title: Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.
Volume: 9
Issue: 5
Pages: 447-62
Publication
First Author: Zhu Y
Year: 2013
Journal: PLoS One
Title: Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.
Volume: 8
Issue: 1
Pages: e54221
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari