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Search results 1 to 100 out of 152 for Rrn3

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
54700 | RRN3
Type: gene
Organism: human
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Gene
100497648 | rrn3
Type: gene
Organism: frog, western clawed
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Gene
304714 | Rrn3
Type: gene
Organism: rat
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Gene
479838 | RRN3
Type: gene
Organism: dog, domestic
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Gene
741314 | RRN3
Type: gene
Organism: chimpanzee
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Gene
515964 | RRN3
Type: gene
Organism: cattle
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Gene
416414 | RRN3
Type: gene
Organism: chicken
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Gene
558718 | rrn3
Type: gene
Organism: zebrafish
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Gene
713500 | RRN3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1925255 | Rrn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
653390 | RRN3P2
Type: gene
Organism: human
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Gene
730092 | RRN3P1
Type: gene
Organism: human
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Gene
100129955 | RRN3P4
Type: gene
Organism: human
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Gene
100131998 | RRN3P3
Type: gene
Organism: human
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Publication
28715449 | J:244454
First Author: Herdman C
Year: 2017
Journal: PLoS Genet
Title: A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription.
Volume: 13
Issue: 7
Pages: e1006899
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Publication
38745938 | J:348364
 
First Author: Radlicka-Borysewska A
Year: 2024
Journal: Front Neurosci
Title: Non-motor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson's disease.
Volume: 18
Pages: 1375265
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Publication
31110473 | J:351886
 
First Author: Kreiner G
Year: 2019
Journal: Front Mol Neurosci
Title: Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases.
Volume: 12
Pages: 106
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Publication
30918302 | J:275901
First Author: Kreiner G
Year: 2019
Journal: Sci Rep
Title: Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.
Volume: 9
Issue: 1
Pages: 5262
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Publication
24273493 | J:311997
 
First Author: Kiryk A
Year: 2013
Journal: Front Cell Neurosci
Title: Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons.
Volume: 7
Pages: 207
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Publication
23764776 | J:228618
First Author: Kreiner G
Year: 2013
Journal: Cell Death Differ
Title: A neuroprotective phase precedes striatal degeneration upon nucleolar stress.
Volume: 20
Issue: 11
Pages: 1455-64
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Publication
34880223 | J:318006
First Author: Sönmez A
Year: 2021
Journal: Cell Death Dis
Title: Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression.
Volume: 12
Issue: 12
Pages: 1139
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Publication
19036968 | J:142505
First Author: Parlato R
Year: 2008
Journal: J Neurosci
Title: Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice.
Volume: 28
Issue: 48
Pages: 12759-64
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Publication
12015311 | -
First Author: Cavanaugh AH
Year: 2002
Journal: J Biol Chem
Title: Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.
Volume: 277
Issue: 30
Pages: 27423-32
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Publication
21228155 | J:168232
First Author: Rieker C
Year: 2011
Journal: J Neurosci
Title: Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.
Volume: 31
Issue: 2
Pages: 453-60
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Protein Coding Gene
MGP_129S1SvImJ_G0022535 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022501 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0020470 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_AJ_G0022497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1925255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022344 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022963 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016176 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021365 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8413268 | J:15147
First Author: Schnapp A
Year: 1993
Journal: Mol Cell Biol
Title: Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.
Volume: 13
Issue: 11
Pages: 6723-32
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Publication
28360124 | J:242309
First Author: Evsyukov V
Year: 2017
Journal: Dis Model Mech
Title: Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models.
Volume: 10
Issue: 5
Pages: 633-643
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Publication
19217408 | J:146620
First Author: Schmitz KM
Year: 2009
Journal: Mol Cell
Title: TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.
Volume: 33
Issue: 3
Pages: 344-53
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Publication
15989966 | J:99711
First Author: Yuan X
Year: 2005
Journal: Mol Cell
Title: Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.
Volume: 19
Issue: 1
Pages: 77-87
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Publication
18559419 | J:139753
First Author: Bierhoff H
Year: 2008
Journal: Mol Cell Biol
Title: Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I.
Volume: 28
Issue: 16
Pages: 4988-98
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Protein
B2RS91
Organism: Mus musculus/domesticus
Length: 656  
Fragment?: false
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Publication
8670901 | -
First Author: Yamamoto RT
Year: 1996
Journal: EMBO J
Title: RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template.
Volume: 15
Issue: 15
Pages: 3964-73
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
12646563 | -
First Author: Hirschler-Laszkiewicz I
Year: 2003
Journal: J Biol Chem
Title: Rrn3 becomes inactivated in the process of ribosomal DNA transcription.
Volume: 278
Issue: 21
Pages: 18953-9
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Protein
Q3TD74
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Protein Domain
IPR007991 | RNA_pol_I_trans_ini_fac_RRN3
Type: Family
Description: This family consists of several eukaryotic proteins which are homologous to the Saccharomyces cerevisiae RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in the S. cerevisiae []RNA polymerase I complex within the nucleolus.In mammalian cells, the phosphorylation state of Rrn3 regulates rDNA transcription by determining the steady-stateconcentration of the Rrn3 [].
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Gene
745676 | LOC745676
Type: gene
Organism: chimpanzee
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Gene
100615882 | LOC100615882
Type: gene
Organism: chimpanzee
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Gene
100426752 | LOC100426752
Type: gene
Organism: macaque, rhesus
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Gene
443681 | rrn3.L
Type: gene
Organism: frog, African clawed
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UniProt Feature
UniProt Feature
Begin: 1
Description: RNA polymerase I-specific transcription initiation factor RRN3
Type: chain
End: 656
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Allele
Rrn3<+> | MGI:3053162
   
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); wild type
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Allele
Rrn3<tm1.1Igt> | MGI:3584035
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); targeted mutation 1.1, Ingrid Grummt
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Rrn3<tm1.2Igt> | MGI:3584037
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); targeted mutation 1.2, Ingrid Grummt
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Rrn3<Gt(YHC051)Byg> | MGI:3876177
 
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); gene trap YHC051, BayGenomics
Allele Type: Gene trapped
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Allele
Rrn3<Gt(YHC042)Byg> | MGI:3876183
 
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); gene trap YHC042, BayGenomics
Allele Type: Gene trapped
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Allele
Rrn3<Gt(CSH737)Byg> | MGI:3878911
 
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); gene trap CSH737, BayGenomics
Allele Type: Gene trapped
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Allele
Rrn3<Gt(XA093)Byg> | MGI:4123859
 
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); gene trap XA093, BayGenomics
Allele Type: Gene trapped
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Allele
Rrn3<Gt(OST10212)Lex> | MGI:4137566
 
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); gene trap OST10212, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Rrn3<Gt(OST113618)Lex> | MGI:4189096
 
Name: RRN3 RNA polymerase I transcription factor homolog (yeast); gene trap OST113618, Lexicon Genetics
Allele Type: Gene trapped
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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