Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
RctB is a RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. It probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester [, , , ]. In worms, this protein has as a neuroprotective role in the age-dependent degeneration of dopamine neurons []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
505
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
505
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kosmaczewski SG |
Year: |
2014 |
Journal: |
EMBO Rep |
Title: |
The RtcB RNA ligase is an essential component of the metazoan unfolded protein response. |
Volume: |
15 |
Issue: |
12 |
Pages: |
1278-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Englert M |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. |
Volume: |
109 |
Issue: |
38 |
Pages: |
15235-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka N |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
RtcB is the RNA ligase component of an Escherichia coli RNA repair operon. |
Volume: |
286 |
Issue: |
10 |
Pages: |
7727-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li R |
Year: |
2021 |
Journal: |
Reproduction |
Title: |
YY1 and RTCB in mouse uterine decidualization and embryo implantation. |
Volume: |
162 |
Issue: |
6 |
Pages: |
461-472 |
|
•
•
•
•
•
|
Publication |
First Author: |
Desai KK |
Year: |
2012 |
Journal: |
Biochemistry |
Title: |
tRNA ligase catalyzes the GTP-dependent ligation of RNA with 3'-phosphate and 5'-hydroxyl termini. |
Volume: |
51 |
Issue: |
7 |
Pages: |
1333-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ray A |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway. |
Volume: |
34 |
Issue: |
48 |
Pages: |
16076-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2010 |
Journal: |
Biochem Biophys Res Commun |
Title: |
HSPC117 deficiency in cloned embryos causes placental abnormality and fetal death. |
Volume: |
397 |
Issue: |
3 |
Pages: |
407-12 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Publication |
First Author: |
Jurkin J |
Year: |
2014 |
Journal: |
EMBO J |
Title: |
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. |
Volume: |
33 |
Issue: |
24 |
Pages: |
2922-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu Y |
Year: |
2014 |
Journal: |
Mol Cell |
Title: |
A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB. |
Volume: |
55 |
Issue: |
5 |
Pages: |
758-70 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1332023 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1332024 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
1x |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1332023 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1332024 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
10x |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1332023 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1332024 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
100x |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1332023 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604211 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1332024 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
1x |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1332023 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604211 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1332024 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
10x |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1332023 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604211 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1332024 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
100x |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360464 |
|
Stage: |
TS04 |
Assay Id: |
MGI:5817214 |
Age: |
embryonic day 3.5 |
|
|
Specimen Label: |
IVP |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817210 |
Assay Type: |
Western blot |
Annotation Date: |
2017-01-11 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5817217 |
Age: |
postnatal |
|
|
Specimen Label: |
None |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160508 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160658 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160508 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160658 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160508 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160658 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160508 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160658 |
|
Stage: |
TS08 |
Assay Id: |
MGI:5817221 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5817222 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817211 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5817224 |
Age: |
embryonic day 19.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817210 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160414 |
Pattern: |
Not Specified |
Stage: |
TS04 |
Assay Id: |
MGI:5817220 |
Age: |
embryonic day 3.5 |
|
Note: |
Expression was detected in the cytoplasm of blastomeres in both the inner cell mass and trophectoderm of blastocysts. |
Specimen Label: |
2B B1-3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5817210 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160464 |
Pattern: |
Not Specified |
Stage: |
TS04 |
Assay Id: |
MGI:5817220 |
Age: |
embryonic day 3.5 |
|
Note: |
Expression was detected in the cytoplasm of blastomeres in both the inner cell mass and trophectoderm of blastocysts. |
Specimen Label: |
2B B1-3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2022 |
Journal: |
Development |
Title: |
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. |
Volume: |
149 |
Issue: |
19 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang T |
Year: |
2015 |
Journal: |
Stem Cells |
Title: |
Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress. |
Volume: |
33 |
Issue: |
7 |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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UniProt Feature |
Begin: |
1 |
Description: |
RNA-splicing ligase RtcB homolog |
Type: |
chain |
End: |
505 |
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