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Search results 1 to 100 out of 125 for Rtkn

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0.049s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Rhotekin is a downstream effector forRho small GTPase []. It is highly expressed in the brain, lung, kidney, muscle, and gastric cancer cells [, ]. Overexpression of rhotekin activates NF-kappa-B and leads to increased survival in gastric adenocarcinoma []. Rhotekin regulates the organisation of the mammalian septin structures, which are heteropolymerised filaments involved in various cellular events such as cytokinesis, apoptosis, vesicular transport and cell polarity []. Rhotekin also plays an important role in the differentiation of neural stem cells (NSCs) into neurons [].
Publication
First Author: Jang W
Year: 1997
Journal: Genomics
Title: Localization of the rhotekin gene RTKN on the physical maps of mouse chromosome 6 and human chromosome 2p13 and exclusion as a candidate for mnd2 and LGMD2B.
Volume: 40
Issue: 3
Pages: 506-7
Protein
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: true
Publication
First Author: Ito H
Year: 2005
Journal: Oncogene
Title: Possible role of Rho/Rhotekin signaling in mammalian septin organization.
Volume: 24
Issue: 47
Pages: 7064-72
Publication
First Author: Iwai T
Year: 2012
Journal: J Neurosci Res
Title: Rhotekin modulates differentiation of cultured neural stem cells to neurons.
Volume: 90
Issue: 7
Pages: 1359-66
Publication
First Author: Nagata K
Year: 2009
Journal: Med Mol Morphol
Title: Interaction of a multi-domain adaptor protein, vinexin, with a Rho-effector, Rhotekin.
Volume: 42
Issue: 1
Pages: 9-15
Publication
First Author: Liu CA
Year: 2004
Journal: J Biomed Sci
Title: Overexpression of rho effector rhotekin confers increased survival in gastric adenocarcinoma.
Volume: 11
Issue: 5
Pages: 661-70
Publication
First Author: Liu CA
Year: 2004
Journal: Oncogene
Title: Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis.
Volume: 23
Issue: 54
Pages: 8731-42
Publication
First Author: Fu Q
Year: 2000
Journal: Genomics
Title: Molecular cloning, expression characterization, and mapping of a novel putative inhibitor of rho GTPase activity, RTKN, to D2S145-D2S286.
Volume: 66
Issue: 3
Pages: 328-32
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Reynaud C
Year: 2000
Journal: J Biol Chem
Title: The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element.
Volume: 275
Issue: 43
Pages: 33962-8
Publication
First Author: Dong N
Year: 2010
Journal: EMBO J
Title: A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis.
Volume: 29
Issue: 8
Pages: 1363-76
Publication  
First Author: Zhou C
Year: 2012
Journal: Mol Cancer
Title: Effect of cancer-associated mutations in the PlexinB1 gene.
Volume: 11
Pages: 11
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: false
Specimen Num: 18
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 27
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 28
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 29
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1789128
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 30
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 31
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1866628
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 32
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 33
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 34
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3515128
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 35
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3528528
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 36
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 38
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 39
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 40
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 41
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 42
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 43
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:2992728
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 44
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:1205354
Age: postnatal week 6-8
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 45
GXD Expression    
Probe: MGI:1205352
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1205354
Age: embryonic day 15-16
Image: st96_477
Specimen Label: None
Detected: true
Specimen Num: 46
Publication
First Author: Park JB
Year: 2005
Journal: Neuron
Title: A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors.
Volume: 45
Issue: 3
Pages: 345-51
Publication
First Author: Saci A
Year: 2005
Journal: Mol Cell
Title: RhoA GTPase regulates B cell receptor signaling.
Volume: 17
Issue: 2
Pages: 205-14
Publication
First Author: Coll PM
Year: 2003
Journal: Mol Biol Cell
Title: Gef1p, a new guanine nucleotide exchange factor for Cdc42p, regulates polarity in Schizosaccharomyces pombe.
Volume: 14
Issue: 1
Pages: 313-23
Publication
First Author: Reid T
Year: 1996
Journal: J Biol Chem
Title: Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.
Volume: 271
Issue: 23
Pages: 13556-60
Publication
First Author: Michael SK
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: High blood pressure arising from a defect in vascular function.
Volume: 105
Issue: 18
Pages: 6702-7
Publication
First Author: Weber JS
Year: 1998
Journal: Genomics
Title: High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6.
Volume: 54
Issue: 1
Pages: 107-15
Publication
First Author: Ryan XP
Year: 2005
Journal: Neuron
Title: The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Volume: 47
Issue: 1
Pages: 85-100
Publication
First Author: Bergo MO
Year: 2004
Journal: J Clin Invest
Title: Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf.
Volume: 113
Issue: 4
Pages: 539-50
Publication
First Author: Rosario CO
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Plk4 is required for cytokinesis and maintenance of chromosomal stability.
Volume: 107
Issue: 15
Pages: 6888-93
Publication
First Author: Margolis SS
Year: 2010
Journal: Cell
Title: EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation.
Volume: 143
Issue: 3
Pages: 442-55
Publication
First Author: Sordella R
Year: 2002
Journal: Dev Cell
Title: Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development.
Volume: 2
Issue: 5
Pages: 553-65