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Search results 1 to 100 out of 111 for Safb2

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: SAFB2 belongs to the scaffold attachment factor B (SAFB) family. It shares protein sequence similarity with SAFB1. Like SAFB1, it also has functions in transcriptional repression and RNA splicing []. Both SAFB1 and SAFB2 play an important role in cancer, particularly in breast tumorigenesis []. Nevertheless, SAFB2 seems to have non-redundant functions in mouse male reproductive tract compared to SAFB1 [].Scaffold attachment factor B (SAFB) family members include SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM. They contain an N-terminal DNA-binding (SAF-A/B, Acinus and PIAS, SAP) domain, an RNA-binding domain (RBD) and an C-terminal arginine/glycine motif RGG/RG domain. Their RGG/RG domain, which partially overlaps with a putative coiled-coil domain, is most conserved and is likely to be involved in protein-protein interactions [].
Publication
First Author: Jiang S
Year: 2015
Journal: Dis Model Mech
Title: Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.
Volume: 8
Issue: 9
Pages: 1121-7
Publication
First Author: Norman M
Year: 2016
Journal: Biochem J
Title: The increasing diversity of functions attributed to the SAFB family of RNA-/DNA-binding proteins.
Volume: 473
Issue: 23
Pages: 4271-4288
Protein
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
Publication
First Author: Sergeant KA
Year: 2007
Journal: J Cell Sci
Title: Alternative RNA splicing complexes containing the scaffold attachment factor SAFB2.
Volume: 120
Issue: Pt 2
Pages: 309-19
Publication
First Author: Hong EA
Year: 2012
Journal: Biochem Soc Trans
Title: SAFB1- and SAFB2-mediated transcriptional repression: relevance to cancer.
Volume: 40
Issue: 4
Pages: 826-30
Protein
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 991  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 572  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12980
Specimen Label: GUDMAP:12980
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5002219
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542773
Age: embryonic day 15.5
Image: GUDMAP:12981
Specimen Label: GUDMAP:12981
Detected: false
Specimen Num: 2
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Chan CW
Year: 2007
Journal: Biochem J
Title: A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.
Volume: 407
Issue: 3
Pages: 355-62
Protein Domain
Type: Family
Description: SLTM belongs to the scaffold attachment factor B (SAFB) family. When overexpressed, it acts as a general inhibitor of transcription that eventually leads to apoptosis [, ].Scaffold attachment factor B (SAFB) family members include SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM. They contain an N-terminal DNA-binding (SAF-A/B, Acinus and PIAS, SAP) domain, an RNA-binding domain (RBD) and an C-terminal arginine/glycine motif RGG/RG domain. Their RGG/RG domain, which partially overlaps with a putative coiled-coil domain, is most conserved and is likely to be involved in protein-protein interactions [].