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Search results 1 to 100 out of 113 for Sap130

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
79595 | SAP130
Type: gene
Organism: human
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Gene
100127690 | sap130
Type: gene
Organism: frog, western clawed
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Gene
307527 | Sap130
Type: gene
Organism: rat
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Gene
476102 | SAP130
Type: gene
Organism: dog, domestic
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Gene
470529 | SAP130
Type: gene
Organism: chimpanzee
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Gene
535754 | SAP130
Type: gene
Organism: cattle
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Gene
424756 | SAP130
Type: gene
Organism: chicken
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Gene
715151 | SAP130
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1919782 | Sap130
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34556635 | J:331251
First Author: Lv LL
Year: 2021
Journal: Cell Death Dis
Title: SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury.
Volume: 12
Issue: 10
Pages: 866
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Publication
38172660 | J:344163
First Author: Chen CH
Year: 2024
Journal: BMC Mol Cell Biol
Title: Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function.
Volume: 25
Issue: 1
Pages: 2
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Publication
18776906 | J:141143
First Author: Yamasaki S
Year: 2008
Journal: Nat Immunol
Title: Mincle is an ITAM-coupled activating receptor that senses damaged cells.
Volume: 9
Issue: 10
Pages: 1179-88
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Publication
34890862 | J:318908
 
First Author: Wilson RL
Year: 2022
Journal: Placenta
Title: Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome.
Volume: 117
Pages: 131-138
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Protein
A0A3Q4EC23
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
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Publication
28530678 | J:242757
First Author: Liu X
Year: 2017
Journal: Nat Genet
Title: The complex genetics of hypoplastic left heart syndrome.
Volume: 49
Issue: 7
Pages: 1152-1159
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Publication
29569026 | J:270983
First Author: Yagi H
Year: 2018
Journal: Pediatr Cardiol
Title: The Genetic Landscape of Hypoplastic Left Heart Syndrome.
Volume: 39
Issue: 6
Pages: 1069-1081
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Publication
39774941 | J:360819
First Author: Gabriel GC
Year: 2025
Journal: Nat Commun
Title: Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease.
Volume: 16
Issue: 1
Pages: 469
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Publication
29355515 | J:261106
First Author: Kim JW
Year: 2018
Journal: Am J Pathol
Title: Spliceosome-Associated Protein 130 Exacerbates Alcohol-Induced Liver Injury by Inducing NLRP3 Inflammasome-Mediated IL-1β in Mice.
Volume: 188
Issue: 4
Pages: 967-980
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Protein Coding Gene
MGP_CAROLIEiJ_G0022064 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023948 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919782 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024048 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024129 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024042 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018798 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022975 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21490601 | J:172063
First Author: Williams K
Year: 2011
Journal: Nature
Title: TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Volume: 473
Issue: 7347
Pages: 343-8
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Publication
18986647 | J:148628
First Author: Kim S
Year: 2009
Journal: Biol Psychiatry
Title: An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.
Volume: 65
Issue: 5
Pages: 425-31
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Publication
9651585 | J:320044
First Author: Zhang Y
Year: 1998
Journal: Mol Cell
Title: SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex.
Volume: 1
Issue: 7
Pages: 1021-31
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Publication
28554894 | J:243422
First Author: Streubel G
Year: 2017
Journal: EMBO J
Title: Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.
Volume: 36
Issue: 15
Pages: 2216-2232
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Publication
22865885 | J:320043
First Author: Muñoz IM
Year: 2012
Journal: J Biol Chem
Title: Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.
Volume: 287
Issue: 39
Pages: 32346-53
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Publication
22984288 | J:320045
First Author: Smith KT
Year: 2012
Journal: Mol Cell Proteomics
Title: Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.
Volume: 11
Issue: 12
Pages: 1815-28
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Publication
21937600 | J:178818
First Author: Wang B
Year: 2011
Journal: Development
Title: Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.
Volume: 138
Issue: 20
Pages: 4487-97
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Protein
J3QNK5
Organism: Mus musculus/domesticus
Length: 1057  
Fragment?: false
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Protein
A0A0R4J060
Organism: Mus musculus/domesticus
Length: 1056  
Fragment?: false
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Protein
Q8BIH0
Organism: Mus musculus/domesticus
Length: 1057  
Fragment?: false
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Publication
29078390 | J:249035
First Author: Kannan M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.
Volume: 114
Issue: 44
Pages: E9308-E9317
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Histone deacetylase complex subunit SAP130
Type: chain
End: 1057
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Protein Domain
IPR024137 | His_deAcase_cplx_SAP130
Type: Family
Description: Histone acetylation plays a key role in the regulation of gene expression. The chromatin structure and accessibility of genes to transcription factors isregulated by enzymes that acetylate and deacetylate histones. The Sin3A-histone deacetylase (HDAC) co-repressor complex consists of multiple proteins and regulates gene expression by deacetylating histones.SAP130 (Sin3-associated protein 130) is a component of the histone deacetylase-dependent co-repressor complex mSin3A that acts as a transcriptional repressor. It may function in the assembly and/or enzymatic activity of mSin3A or in mediating interactions between the complex and other regulatory complexes [].
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Protein
Q8BIH0-2
Organism: Mus musculus/domesticus
Length: 879  
Fragment?: false
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Protein
Q8BIH0-3
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
A0A3Q4EGN6
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: true
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Publication
12724404 | J:85478
First Author: Fleischer TC
Year: 2003
Journal: Mol Cell Biol
Title: Identification and characterization of three new components of the mSin3A corepressor complex.
Volume: 23
Issue: 10
Pages: 3456-67
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Protein Coding Gene
MGI:1289341 | Sf3b3
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
b2b635Clo | MGI:5311367
 
Name: Mutant line 635; Bench to Bassinet Program (B2B/CVDC), mutation 635 Cecilia Lo
Allele Type: Chemically induced (ENU)
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Protein Domain
IPR031963 | SAP130_C
Type: Domain
Description: SAP130 (Sin3-associated protein 130) is a component of the histone deacetylase-dependent co-repressor complex mSin3A that acts as a transcriptional repressor. It may function in the assembly and/or enzymatic activity of mSin3A or in mediating interactions between the complex and other regulatory complexes [].This entry represents the C-terminal domain of SAP130.
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Strain
MGI:5432517 | C57BL/6J-b2b635Clo/J
Attribute String: coisogenic, chemically induced mutation, mutant strain
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Strain
MGI:5312701 | C57BL/6J-b2b635Clo
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Allele
Pcdha9<b2b635.1Clo> | MGI:5906282
Name: protocadherin alpha 9; Bench to Bassinet Program (B2B/CVDC), mutation 635.1 Cecilia Lo
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Genotype
Genotype
Symbol: b2b635Clo/b2b635Clo
Background: C57BL/6J-b2b635Clo
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5906290 | C57BL/6J-Pcdha9<b2b635.1Clo>
Attribute String: mutant strain, coisogenic, chemically induced mutation
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Publication
34888534 | J:320813
 
First Author: Teekakirikul P
Year: 2021
Journal: HGG Adv
Title: Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease.
Volume: 2
Issue: 3
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Allele
Sap130<b2b635.2Clo> | MGI:5906284
Name: Sin3A associated protein; Bench to Bassinet Program (B2B/CVDC), mutation 635.2 Cecilia Lo
Allele Type: Chemically induced (ENU)
Attribute String: Hypomorph, Modified isoform(s)
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Genotype
Genotype
Symbol: Pcdha9/Pcdha9
Background: C57BL/6J-Pcdha9
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5906295 | C57BL/6J-Sap130<b2b635.2Clo>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Genotype
Genotype
Symbol: Sap130/Sap130
Background: C57BL/6J-Sap130 Pcdha9
Zygosity: hm
Has Mutant Allele: true
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