Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
SASH3, also called SLY/SLY1 (SH3-domain containing protein expressed in lymphocytes), is expressed exclusively in lymhocytes and is essential in the full activation of adaptive immunity []. It is involved in the signaling of T cell receptors []. It was the first described member of the SLY family of proteins, which are adaptor proteins containing a central conserved region with a bipartite nuclear localization signal (NLS) as well as SAM (sterile alpha motif) and SH3 domains []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Beer S |
Year: |
2001 |
Journal: |
Biochim Biophys Acta |
Title: |
Molecular cloning and characterization of a novel SH3 protein (SLY) preferentially expressed in lymphoid cells. |
Volume: |
1520 |
Issue: |
1 |
Pages: |
89-93 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
380
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Reis B |
Year: |
2009 |
Journal: |
BMC Immunol |
Title: |
The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development. |
Volume: |
10 |
|
Pages: |
38 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Beer S |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Impaired immune responses and prolonged allograft survival in Sly1 mutant mice. |
Volume: |
25 |
Issue: |
21 |
Pages: |
9646-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gruber LC |
Year: |
2023 |
Journal: |
Eur J Immunol |
Title: |
Knockout of SLy1 decreases double-negative thymocyte proliferation and protects mice from p53-induced tumor formation. |
Volume: |
53 |
Issue: |
1 |
Pages: |
e2250017 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_08 |
|
Specimen Label: |
euxassay_008188_08 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_09 |
|
Specimen Label: |
euxassay_008188_09 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_10 |
|
Specimen Label: |
euxassay_008188_10 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_11 |
|
Specimen Label: |
euxassay_008188_11 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_12 |
|
Specimen Label: |
euxassay_008188_12 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_13 |
|
Specimen Label: |
euxassay_008188_13 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_14 |
|
Specimen Label: |
euxassay_008188_14 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_15 |
|
Specimen Label: |
euxassay_008188_15 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_16 |
|
Specimen Label: |
euxassay_008188_16 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733123 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_17 |
|
Specimen Label: |
euxassay_008188_17 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_11 |
|
Specimen Label: |
euxassay_008188_11 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_12 |
|
Specimen Label: |
euxassay_008188_12 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_13 |
|
Specimen Label: |
euxassay_008188_13 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_14 |
|
Specimen Label: |
euxassay_008188_14 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1030869 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4827873 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_008188_15 |
|
Specimen Label: |
euxassay_008188_15 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beer S |
Year: |
2001 |
Journal: |
GenBank Submission |
Title: |
Mus musculus mRNA for SLY protein |
|
|
Pages: |
AJ306422 |
|
•
•
•
•
•
|
Publication |
First Author: |
Riel JM |
Year: |
2019 |
Journal: |
Genes (Basel) |
Title: |
Rescue of Sly Expression Is Not Sufficient to Rescue Spermiogenic Phenotype of Mice with Deletions of Y Chromosome Long Arm. |
Volume: |
10 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Schäll D |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
SLy1 regulates T-cell proliferation during Listeria monocytogenes infection in a Foxo1-dependent manner. |
Volume: |
45 |
Issue: |
11 |
Pages: |
3087-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scheikl T |
Year: |
2009 |
Journal: |
Mol Immunol |
Title: |
Reduced notch activity is associated with an impaired marginal zone B cell development and function in Sly1 mutant mice. |
Volume: |
46 |
Issue: |
5 |
Pages: |
969-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
SAM and SH3 domain containing 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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