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Search results 1 to 85 out of 85 for Scarf1

0.029s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: The class F scavenger receptor 1 (SCARF1/SREC-I) contains epidermal growth factor (EGF)-like repeats in its extracellular domain, followed by a long C-terminal cytoplasmic tail composed of serine and proline-rich regions. SCARF1 is an endocytic receptor for acetylated low density lipoprotein, HSP70, HSP90, calreticulin, gp96, and GP2 [, , , , ]. Dendritic cells (DCs),macrophages and endothelial cells use SCARF1 to recognize and engulf apoptotic cells via the complement component C1q; this mediates apoptotic cells clearance, antigen clearance and prevents autoimmunity [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ramirez-Ortiz ZG
Year: 2013
Journal: Nat Immunol
Title: The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.
Volume: 14
Issue: 9
Pages: 917-26
Publication
First Author: Murshid A
Year: 2010
Journal: J Immunol
Title: Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.
Volume: 185
Issue: 5
Pages: 2903-17
Publication
First Author: Tamura Y
Year: 2004
Journal: J Biol Chem
Title: Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide.
Volume: 279
Issue: 30
Pages: 30938-44
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Publication
First Author: Means TK
Year: 2009
Journal: J Exp Med
Title: Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36.
Volume: 206
Issue: 3
Pages: 637-53
Publication
First Author: Hölzl MA
Year: 2011
Journal: Cell Immunol
Title: The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I).
Volume: 267
Issue: 2
Pages: 88-93
Publication
First Author: Berwin B
Year: 2004
Journal: J Biol Chem
Title: SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.
Volume: 279
Issue: 49
Pages: 51250-7
Publication
First Author: Murshid A
Year: 2014
Journal: Immunobiology
Title: Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I.
Volume: 219
Issue: 12
Pages: 924-31
Protein
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
Publication
First Author: Ishii J
Year: 2002
Journal: J Biol Chem
Title: SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain.
Volume: 277
Issue: 42
Pages: 39696-702
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3513329
Assay Type: Western blot
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3513338
Age: postnatal adult
Image: 5
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3513329
Assay Type: Western blot
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3513338
Age: embryonic day 18.0
Image: 5
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3513329
Assay Type: Western blot
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3513338
Age: postnatal adult
Image: 5
Specimen Label: Spinal cord
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3513329
Assay Type: Western blot
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:3513338
Age: embryonic day 18.0
Image: 5
Specimen Label: Spinal cord
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3513329
Assay Type: Western blot
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:3513338
Age: postnatal adult
Image: 5
Specimen Label: DRG
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3513329
Assay Type: Western blot
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Stage: TS26
Assay Id: MGI:3513338
Age: embryonic day 18.0
Image: 5
Specimen Label: DRG
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6780101
Assay Type: RT-PCR
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6780122
Age: embryonic day 3.5
Image: 6
Specimen Label: Bl
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6780101
Assay Type: RT-PCR
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:6780122
Age: postnatal adult
Image: 6
Specimen Label: PC
Detected: true
Specimen Num: 2
Publication
First Author: Shibata M
Year: 2004
Journal: J Biol Chem
Title: Type F scavenger receptor SREC-I interacts with advillin, a member of the gelsolin/villin family, and induces neurite-like outgrowth.
Volume: 279
Issue: 38
Pages: 40084-90
Publication
First Author: Ishii J
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Scavenger receptor expressed by endothelial cells (SREC)-I interacts with protein phosphatase 1alpha in L cells to induce neurite-like outgrowth.
Volume: 360
Issue: 1
Pages: 269-74
Publication
First Author: Hasegawa H
Year: 2007
Journal: J Neurosci
Title: Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene.
Volume: 27
Issue: 52
Pages: 14404-14
Publication
First Author: Pisko J
Year: 2021
Journal: Sci Rep
Title: Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres.
Volume: 11
Issue: 1
Pages: 9228
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Protein Domain
Type: Family
Description: The class F scavenger receptors (SCARFs or SRECs) have two isoforms, SCARF1/SREC-I and SCARF2/SREC-II. Similar to SREC-I, SREC-II contains multiple epidermal growth factor-like repeats in its extracellular domain. However, in contrast to SREC-I, SREC-II had little activity to internalize modified low density lipoproteins (LDL). SREC-II and SREC-I display strong heterophilic trans-interaction through the extracellular domains []. They are expressed in a specific temporal and spatial pattern during epidermal development [].Mutations in the SCARF2 gene cause Van den Ende-Gupta syndrome (VDEGS), a syndrome characterised by craniofacial and skeletal abnormalities []. The class F scavenger receptor 1 (SCARF1/SREC-I) contains epidermal growth factor (EGF)-like repeats in its extracellular domain, followed by a long C-terminal cytoplasmic tail composed of serine and proline-rich regions. SCARF1 is an endocytic receptor for acetylated low density lipoprotein, HSP70, HSP90, calreticulin, gp96, and GP2 [, , , , ]. Dendritic cells (DCs), macrophages and endothelial cells use SCARF1 to recognize and engulf apoptotic cells via the complement component C1q; this mediates apoptotic cells clearance, antigen clearance and prevents autoimmunity [].
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
Publication
First Author: Hwang M
Year: 2005
Journal: Gene Expr Patterns
Title: The temporal and spatial expression of the novel Ca++-binding proteins, Scarf and Scarf2, during development and epidermal differentiation.
Volume: 5
Issue: 6
Pages: 801-8
Publication
First Author: Anastasio N
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome.
Volume: 87
Issue: 4
Pages: 553-9
Protein
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 566  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7