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Search results 1 to 97 out of 97 for Scarf2

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
91179 | SCARF2
Type: gene
Organism: human
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Gene
458665 | SCARF2
Type: gene
Organism: chimpanzee
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Gene
528108 | SCARF2
Type: gene
Organism: cattle
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Gene
100684936 | SCARF2
Type: gene
Organism: dog, domestic
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Gene
772263 | SCARF2
Type: gene
Organism: chicken
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Gene
100329632 | scarf2
Type: gene
Organism: zebrafish
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Gene
695466 | SCARF2
Type: gene
Organism: macaque, rhesus
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Gene
100485666 | scarf2
Type: gene
Organism: frog, western clawed
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Gene
287949 | Scarf2
Type: gene
Organism: rat
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Protein Domain
IPR033327 | Scarf2
Type: Family
Description: The class F scavenger receptors (SCARFsor SRECs) have two isoforms, SCARF1/SREC-I and SCARF2/SREC-II. Similar to SREC-I, SREC-II contains multiple epidermal growth factor-like repeats in its extracellular domain. However, in contrast to SREC-I, SREC-II had little activity to internalize modified low density lipoproteins (LDL). SREC-II and SREC-I display strong heterophilic trans-interaction through the extracellular domains []. They are expressed in a specific temporal and spatial pattern during epidermal development [].Mutations in the SCARF2 gene cause Van den Ende-Gupta syndrome (VDEGS), a syndrome characterised by craniofacial and skeletal abnormalities [].
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Protein Coding Gene
MGI:1858430 | Scarf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12154095 | J:79485
First Author: Ishii J
Year: 2002
Journal: J Biol Chem
Title: SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain.
Volume: 277
Issue: 42
Pages: 39696-702
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Publication
20887961 | -
First Author: Anastasio N
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome.
Volume: 87
Issue: 4
Pages: 553-9
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GXD Expression
GXD Expression
     
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191251
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Scarf2
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191251
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Scarf2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191251
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Scarf2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191251
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Scarf2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191251
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Scarf2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191251
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Scarf2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6182815
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191251
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Scarf2
Detected: false
Specimen Num: 7
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Publication
15922673 | J:99529
First Author: Hwang M
Year: 2005
Journal: Gene Expr Patterns
Title: The temporal and spatial expression of the novel Ca++-binding proteins, Scarf and Scarf2, during development and epidermal differentiation.
Volume: 5
Issue: 6
Pages: 801-8
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Protein
Q6W3E0
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
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Protein
A0A338P7B0
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
P59222
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
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Protein
A0A338P7B2
Organism: Mus musculus/domesticus
Length: 566  
Fragment?: false
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Protein
Q58A84
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
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Publication
15145948 | J:91911
First Author: Tamura Y
Year: 2004
Journal: J Biol Chem
Title: Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide.
Volume: 279
Issue: 30
Pages: 30938-44
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Protein Coding Gene
MGP_CAROLIEiJ_G0020526 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022529 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022322 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1858430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021850 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022293 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022399 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022420 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016231 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021421 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851431
Note: kidney
Specimen Label: UC Davis_1851431
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851432
Specimen Label: UC Davis_1851432
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851428
Specimen Label: UC Davis_1851428
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851429
Specimen Label: UC Davis_1851429
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851430
Specimen Label: UC Davis_1851430
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1802528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851434
Note: chest bone
Specimen Label: UC Davis_1851434
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1802528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851435
Note: chest bone
Specimen Label: UC Davis_1851435
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1802528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691557
Age: postnatal adult
Image: UC Davis_1851436
Note: chest bone
Specimen Label: UC Davis_1851436
Detected: true
Specimen Num: 8
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Publication
27546376 | J:236397
First Author: Bildsoe H
Year: 2016
Journal: Dev Biol
Title: Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance.
Volume: 418
Issue: 1
Pages: 189-203
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Publication
10704284 | J:60871
First Author: Lund J
Year: 2000
Journal: Genomics
Title: Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2.
Volume: 63
Issue: 3
Pages: 374-83
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Coding Gene
MGI:3511177 | Calm5
Type: protein_coding_gene
Organism: mouse, laboratory
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DO Term
DOID:0111699 | Van den Ende-Gupta syndrome
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Publication
20686127 | J:163244
First Author: Murshid A
Year: 2010
Journal: J Immunol
Title: Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.
Volume: 185
Issue: 5
Pages: 2903-17
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Publication
21190681 | -
First Author: Hölzl MA
Year: 2011
Journal: Cell Immunol
Title: The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I).
Volume: 267
Issue: 2
Pages: 88-93
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Publication
15371419 | -
First Author: Berwin B
Year: 2004
Journal: J Biol Chem
Title: SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.
Volume: 279
Issue: 49
Pages: 51250-7
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Publication
23892722 | J:208237
First Author: Ramirez-Ortiz ZG
Year: 2013
Journal: Nat Immunol
Title: The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.
Volume: 14
Issue: 9
Pages: 917-26
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Publication
25155057 | -
First Author: Murshid A
Year: 2014
Journal: Immunobiology
Title: Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I.
Volume: 219
Issue: 12
Pages: 924-31
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Protein Domain
IPR042635 | SREC1/2
Type: Family
Description: The class F scavenger receptors (SCARFs or SRECs) have two isoforms, SCARF1/SREC-I and SCARF2/SREC-II. Similar to SREC-I, SREC-II contains multiple epidermal growth factor-like repeats in its extracellular domain. However, in contrast to SREC-I, SREC-II had little activity to internalize modified low density lipoproteins (LDL). SREC-II and SREC-I display strong heterophilic trans-interaction through the extracellular domains []. They are expressed in a specific temporal and spatial pattern during epidermal development [].Mutations in the SCARF2 gene cause Van den Ende-Gupta syndrome (VDEGS), a syndrome characterised by craniofacial and skeletal abnormalities []. The class F scavenger receptor 1 (SCARF1/SREC-I) contains epidermal growth factor (EGF)-like repeats in its extracellular domain, followed by a long C-terminal cytoplasmic tail composed of serine and proline-rich regions. SCARF1 is an endocytic receptor for acetylated low density lipoprotein, HSP70, HSP90, calreticulin, gp96, and GP2 [, , , , ]. Dendritic cells (DCs), macrophages and endothelial cells use SCARF1 to recognize and engulf apoptotic cells via the complement component C1q; this mediates apoptotic cells clearance, antigen clearance and prevents autoimmunity [].
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Protein
Q5ND28
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Protein
B7ZC28
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
Q68EF1
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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