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Search results 1 to 100 out of 1025 for Scgb1a1

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0.038s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Rawlins EL
Year: 2009
Journal: Cell Stem Cell
Title: The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.
Volume: 4
Issue: 6
Pages: 525-34
Publication
First Author: Bi G
Year: 2018
Journal: FASEB J
Title: Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific NAMPT knockdown.
Volume: 32
Issue: 7
Pages: 3583-3596
Publication
First Author: Jaffer OA
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model.
Volume: 52
Issue: 1
Pages: 106-15
Publication
First Author: Gimenes-Junior J
Year: 2019
Journal: Sci Rep
Title: FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells.
Volume: 9
Issue: 1
Pages: 18180
Publication
First Author: Zheng D
Year: 2012
Journal: PLoS One
Title: Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza.
Volume: 7
Issue: 10
Pages: e48451
Publication
First Author: Tata PR
Year: 2013
Journal: Nature
Title: Dedifferentiation of committed epithelial cells into stem cells in vivo.
Volume: 503
Issue: 7475
Pages: 218-23
Publication
First Author: Lu Y
Year: 2010
Journal: PLoS One
Title: Evidence that SOX2 overexpression is oncogenic in the lung.
Volume: 5
Issue: 6
Pages: e11022
Publication
First Author: Chen H
Year: 2012
Journal: Stem Cells
Title: Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury.
Volume: 30
Issue: 9
Pages: 1948-60
Publication
First Author: Watson JK
Year: 2015
Journal: Cell Rep
Title: Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium.
Volume: 12
Issue: 1
Pages: 90-101
Publication
First Author: Yee M
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.
Volume: 56
Issue: 4
Pages: 453-464
Publication
First Author: Akram KM
Year: 2018
Journal: Mucosal Immunol
Title: An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection.
Volume: 11
Issue: 1
Pages: 71-81
Publication
First Author: Zheng D
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Evidence for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma.
Volume: 50
Issue: 3
Pages: 595-604
Publication
First Author: Baluk P
Year: 2020
Journal: Am J Pathol
Title: Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury.
Volume: 190
Issue: 12
Pages: 2355-2375
Publication
First Author: Tian B
Year: 2018
Journal: Cell Rep
Title: Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation.
Volume: 23
Issue: 4
Pages: 1138-1151
Publication
First Author: Malvin NP
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Autophagy proteins are required for club cell structure and function in airways.
Volume: 317
Issue: 2
Pages: L259-L270
Publication
First Author: Teisanu RM
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.
Volume: 44
Issue: 6
Pages: 794-803
Publication
First Author: Galvis LA
Year: 2015
Journal: Development
Title: Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung.
Volume: 142
Issue: 8
Pages: 1458-69
Publication  
First Author: Jaramillo AM
Year: 2019
Journal: JCI Insight
Title: Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.
Volume: 4
Issue: 6
Publication
First Author: Liu Q
Year: 2019
Journal: Nat Genet
Title: Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.
Volume: 51
Issue: 4
Pages: 728-738
Publication
First Author: Liu K
Year: 2020
Journal: J Biol Chem
Title: Triple-cell lineage tracing by a dual reporter on a single allele.
Volume: 295
Issue: 3
Pages: 690-700
Publication
First Author: Xu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
Volume: 109
Issue: 13
Pages: 4910-5
Publication  
First Author: Tien JC
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.
Volume: 118
Issue: 20
Publication
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
Publication
First Author: Moon HG
Year: 2018
Journal: Immunity
Title: Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization.
Volume: 49
Issue: 2
Pages: 275-287.e5
Publication  
First Author: Tilston-Lunel A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
Volume: 118
Issue: 18
Publication
First Author: Khatri A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia.
Volume: 116
Issue: 5
Pages: 1603-1612
Publication
First Author: Rock JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
Volume: 108
Issue: 52
Pages: E1475-83
Publication
First Author: Barkauskas CE
Year: 2013
Journal: J Clin Invest
Title: Type 2 alveolar cells are stem cells in adult lung.
Volume: 123
Issue: 7
Pages: 3025-36
Publication
First Author: Lee JH
Year: 2017
Journal: Cell
Title: Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6.
Volume: 170
Issue: 6
Pages: 1149-1163.e12
Publication
First Author: Vaughan AE
Year: 2015
Journal: Nature
Title: Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.
Volume: 517
Issue: 7536
Pages: 621-5
Publication
First Author: De la Garza MM
Year: 2018
Journal: Oncotarget
Title: COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation.
Volume: 9
Issue: 68
Pages: 32972-32983
Publication
First Author: Xu X
Year: 2014
Journal: Genes Dev
Title: The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2.
Volume: 28
Issue: 17
Pages: 1929-39
Publication
First Author: Montoro DT
Year: 2018
Journal: Nature
Title: A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
Volume: 560
Issue: 7718
Pages: 319-324
Publication
First Author: Pardo-Saganta A
Year: 2015
Journal: Nature
Title: Parent stem cells can serve as niches for their daughter cells.
Volume: 523
Issue: 7562
Pages: 597-601
Publication
First Author: Yang Y
Year: 2018
Journal: Dev Cell
Title: Spatial-Temporal Lineage Restrictions of Embryonic p63+ Progenitors Establish Distinct Stem Cell Pools in Adult Airways.
Volume: 44
Issue: 6
Pages: 752-761.e4
Publication
First Author: Zhao R
Year: 2014
Journal: Dev Cell
Title: Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells.
Volume: 30
Issue: 2
Pages: 151-65
Publication
First Author: Xi Y
Year: 2017
Journal: Nat Cell Biol
Title: Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.
Volume: 19
Issue: 8
Pages: 904-914
Publication
First Author: Yuan T
Year: 2019
Journal: Stem Cell Reports
Title: FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury.
Volume: 12
Issue: 5
Pages: 1041-1055
Publication      
First Author: Wang C
Year: 2018
Journal: J Clin Invest
Title: Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype.
Publication
First Author: Volckaert T
Year: 2017
Journal: Dev Cell
Title: Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells.
Volume: 43
Issue: 1
Pages: 48-59.e5
Publication
First Author: Desai TJ
Year: 2014
Journal: Nature
Title: Alveolar progenitor and stem cells in lung development, renewal and cancer.
Volume: 507
Issue: 7491
Pages: 190-4
Publication
First Author: Li H
Year: 2008
Journal: Genesis
Title: Cre-mediated recombination in mouse Clara cells.
Volume: 46
Issue: 6
Pages: 300-7
Publication
First Author: Winkelmann VE
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia.
Volume: 316
Issue: 1
Pages: L58-L70
Publication
First Author: Moghaddam SJ
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model.
Volume: 40
Issue: 4
Pages: 443-53
Publication
First Author: Caetano MS
Year: 2016
Journal: Cancer Res
Title: IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.
Volume: 76
Issue: 11
Pages: 3189-99
Publication
First Author: Tao S
Year: 2014
Journal: Cancer Res
Title: Oncogenic KRAS confers chemoresistance by upregulating NRF2.
Volume: 74
Issue: 24
Pages: 7430-41
Publication      
First Author: Unver N
Year: 2017
Journal: Int J Cancer
Title: Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol.
Publication
First Author: Zhang Z
Year: 2019
Journal: FASEB J
Title: Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion.
Volume: 33
Issue: 5
Pages: 6226-6238
Publication
First Author: Ahn YH
Year: 2011
Journal: Mol Cell Biol
Title: Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression.
Volume: 31
Issue: 21
Pages: 4270-85
Publication  
First Author: Bauer AK
Year: 2018
Journal: JCI Insight
Title: Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
Volume: 3
Issue: 15
Publication  
First Author: Liu J
Year: 2017
Journal: Lung Cancer
Title: Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis.
Volume: 112
Pages: 47-56
Publication
First Author: Gibbs J
Year: 2014
Journal: Nat Med
Title: An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Volume: 20
Issue: 8
Pages: 919-26
Publication
First Author: Pariollaud M
Year: 2018
Journal: J Clin Invest
Title: Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.
Volume: 128
Issue: 6
Pages: 2281-2296
Publication
First Author: Iwanaga K
Year: 2008
Journal: Cancer Res
Title: Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.
Volume: 68
Issue: 4
Pages: 1119-27
Publication
First Author: Pacheco-Pinedo EC
Year: 2011
Journal: J Clin Invest
Title: Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.
Volume: 121
Issue: 5
Pages: 1935-45
Publication
First Author: Caetano MS
Year: 2018
Journal: Nat Commun
Title: Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.
Volume: 9
Issue: 1
Pages: 4589
Publication
First Author: Deng S
Year: 2020
Journal: Carcinogenesis
Title: Interplay between estrogen and Stat3/NF-κB-driven immunomodulation in lung cancer.
Volume: 41
Issue: 11
Pages: 1529-1542
Publication
First Author: Zhu L
Year: 2019
Journal: Nat Cell Biol
Title: TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.
Volume: 21
Issue: 12
Pages: 1604-1614
Publication
First Author: Ince LM
Year: 2019
Journal: FASEB J
Title: Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells.
Volume: 33
Issue: 1
Pages: 126-139
Publication
First Author: Chang SH
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: T helper 17 cells play a critical pathogenic role in lung cancer.
Volume: 111
Issue: 15
Pages: 5664-9
Publication
First Author: Li S
Year: 2016
Journal: J Clin Invest
Title: Epithelium-generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness.
Volume: 126
Issue: 5
Pages: 1978-82
Publication
First Author: Cunningham PS
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The circadian clock protein REVERBα inhibits pulmonary fibrosis development.
Volume: 117
Issue: 2
Pages: 1139-1147
Publication      
First Author: Liu J
Year: 2015
Journal: Cell Rep
Title: ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.
Publication
First Author: Peng T
Year: 2015
Journal: Nature
Title: Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration.
Volume: 526
Issue: 7574
Pages: 578-82
Publication  
First Author: Liu J
Year: 2019
Journal: Cells
Title: ERBB2 Regulates MED24 during Cancer Progression in Mice with Pten and Smad4 Deletion in the Pulmonary Epithelium.
Volume: 8
Issue: 6
Publication
First Author: Reynolds SD
Year: 2008
Journal: Stem Cells
Title: Conditional stabilization of beta-catenin expands the pool of lung stem cells.
Volume: 26
Issue: 5
Pages: 1337-46
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Liu J
Year: 2019
Journal: Nat Commun
Title: JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression.
Volume: 10
Issue: 1
Pages: 2148
Publication
First Author: Zhang Y
Year: 2008
Journal: Nat Genet
Title: A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.
Volume: 40
Issue: 7
Pages: 862-70
Publication
First Author: Li Q
Year: 2014
Journal: PLoS Genet
Title: Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.
Volume: 10
Issue: 7
Pages: e1004524
Publication
First Author: Snitow ME
Year: 2015
Journal: Development
Title: Ezh2 represses the basal cell lineage during lung endoderm development.
Volume: 142
Issue: 1
Pages: 108-17
Publication
First Author: Li S
Year: 2012
Journal: Development
Title: Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.
Volume: 139
Issue: 14
Pages: 2500-9
Publication
First Author: Wang Y
Year: 2013
Journal: Dev Cell
Title: Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway.
Volume: 24
Issue: 4
Pages: 345-58
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Zhu L
Year: 2019
Journal: Am J Respir Cell Mol Biol
Title: The Club Cell Marker SCGB1A1 Downstream of FOXA2 is Reduced in Asthma.
Volume: 60
Issue: 6
Pages: 695-704
Publication      
First Author: Aidinis V
Year: 2008
Journal: MGI Direct Data Submission
Title: A transgene for the expression of Cre recombinase under control of the Clara cell-specific promoter of Scgb1a1 (secretoglobin, family A, member 1(uteroglobin); CC10)
Allele
Name: secretoglobin, family 1A, member 1 (uteroglobin); endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Publication categories: ProxyCollection
Allele
Name: secretoglobin, family 1A, member 1 (uteroglobin); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
GXD Expression  
Probe: MGI:6376473
Assay Type: Immunohistochemistry
Annotation Date: 2019-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6376482
Age: postnatal adult
Note: Double immunostaining revealed that expression of Foxj1 and Scgb1a1 in the airway are in two mutually exclusive cell populations.
Detected: true
Specimen Num: 1
Allele
Name: secretoglobin, family 1A, member 1 (uteroglobin); targeted mutation 1, Brigid L Hogan
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant strain, congenic, targeted mutation
Genotype
Symbol: Scgb1a1/Scgb1a1<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Allele
Name: transgene insertion, Terence H Rabbitts
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Scgb1a1/Scgb1a1<+>
Background: involves: 129S6/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Scgb1a1/Scgb1a1<+>
Background: involves: 129S6/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bpifa1/Bpifa1 Scgb1a1/Scgb1a1
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Scgb1a1/Scgb1a1<+> Trp53/Trp53<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Scgb1a1/Scgb1a1<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Tanaka T
Year: 2010
Journal: Oncogene
Title: Interfering with RAS-effector protein interactions prevent RAS-dependent tumour initiation and causes stop-start control of cancer growth.
Volume: 29
Issue: 45
Pages: 6064-70
Publication
First Author: Kido T
Year: 2011
Journal: Am J Physiol Lung Cell Mol Physiol
Title: FOXA1 plays a role in regulating secretoglobin 1a1 expression in the absence of CCAAT/enhancer binding protein activities in lung in vivo.
Volume: 300
Issue: 3
Pages: L441-52
Publication
First Author: Chen K
Year: 2016
Journal: Cell Host Microbe
Title: IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.
Volume: 20
Issue: 5
Pages: 596-605
Publication
First Author: Legoux FP
Year: 2015
Journal: Immunity
Title: CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.
Volume: 43
Issue: 5
Pages: 896-908
Publication    
First Author: Spella M
Year: 2019
Journal: Elife
Title: Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.
Volume: 8
Publication
First Author: Oikonomou N
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis.
Volume: 47
Issue: 5
Pages: 566-74
Publication
First Author: Anas AA
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia.
Volume: 56
Issue: 5
Pages: 648-656
Publication
First Author: Vreka M
Year: 2018
Journal: Cancer Res
Title: IκB Kinase α Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma.
Volume: 78
Issue: 11
Pages: 2939-2951