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Search results 1 to 100 out of 1209 for Scgb1a1

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0.042s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:7257857
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7258075
Age: embryonic day 18.5
Image: 2A Bronchiolar TNRC6c-/- Scgb1a1
Note: Expression present and properly localized within mutant lungs, in a similar to that of wild type.
Specimen Label: 2A Bronchiolar TNRC6c-/- Scgb1a1
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6858148
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6863929
Age: postnatal adult
Image: 1F - Scgb1a1
Note: Expression is seen in secretory cells.
Specimen Label: 1F - Scgb1a1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6858148
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6863929
Age: postnatal adult
Image: 1H - Scgb1a1
Note: Expression is seen in secretory cells.
Specimen Label: 1H - Scgb1a1
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7257857
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7258075
Age: embryonic day 18.5
Image: 2A Bronchiolar WT Scgb1a1
Note: Expression in Club cells lining bronchilar airways.
Specimen Label: 2A Bronchiolar WT Scgb1a1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7257857
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7258075
Age: postnatal day 0
Image: 2B Bronchiolar WT Scgb1a1
Note: Expression in Club cells lining bronchilar airways.
Specimen Label: 2B Bronchiolar WT Scgb1a1
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7257857
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3269727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7258075
Age: postnatal day 0
Image: 2B Bronchiolar TNRC6c-/- Scgb1a1
Note: Slightly reduced levels of expression at PN0 compared with wild type and E18.5 mutant lungs.
Specimen Label: 2B Bronchiolar TNRC6c-/- Scgb1a1
Detected: true
Specimen Num: 4
Publication
First Author: Zhu L
Year: 2019
Journal: Am J Respir Cell Mol Biol
Title: The Club Cell Marker SCGB1A1 Downstream of FOXA2 is Reduced in Asthma.
Volume: 60
Issue: 6
Pages: 695-704
GXD Expression
Probe: MGI:5302577
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6863897
Age: postnatal adult
Image: 1F - Scgb1a1
Note: Some expressing cells are secretory cells.
Specimen Label: 1F - Scgb1a1
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:6858139
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6863898
Age: postnatal adult
Image: 1H - Scgb1a1
Note: Some expressing cells are secretory cells.
Specimen Label: 1H - Scgb1a1
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:6376473
Assay Type: Immunohistochemistry
Annotation Date: 2019-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6376482
Age: postnatal adult
Note: Double immunostaining revealed that expression of Foxj1 and Scgb1a1 in the airway are in two mutually exclusive cell populations.
Specimen Label: 2F
Detected: true
Specimen Num: 1
Publication
First Author: Ban Y
Year: 2021
Journal: Nat Cancer
Title: Radiation-activated secretory proteins of Scgb1a1 + club cells increase the efficacy of immune checkpoint blockade in lung cancer.
Volume: 2
Issue: 9
Pages: 919-931
Publication
First Author: Rawlins EL
Year: 2009
Journal: Cell Stem Cell
Title: The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.
Volume: 4
Issue: 6
Pages: 525-34
Publication
First Author: Kido T
Year: 2011
Journal: Am J Physiol Lung Cell Mol Physiol
Title: FOXA1 plays a role in regulating secretoglobin 1a1 expression in the absence of CCAAT/enhancer binding protein activities in lung in vivo.
Volume: 300
Issue: 3
Pages: L441-52
Publication
First Author: Bi G
Year: 2018
Journal: FASEB J
Title: Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific NAMPT knockdown.
Volume: 32
Issue: 7
Pages: 3583-3596
Publication
First Author: Garcia-Arcos I
Year: 2022
Journal: J Lipid Res
Title: LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling.
Volume: 63
Issue: 4
Pages: 100185
Publication
First Author: Zheng D
Year: 2012
Journal: PLoS One
Title: Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza.
Volume: 7
Issue: 10
Pages: e48451
Publication
First Author: Gimenes-Junior J
Year: 2019
Journal: Sci Rep
Title: FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells.
Volume: 9
Issue: 1
Pages: 18180
Publication
First Author: Jaffer OA
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model.
Volume: 52
Issue: 1
Pages: 106-15
Publication
First Author: Liu K
Year: 2020
Journal: J Biol Chem
Title: Genetic lineage tracing with multiple DNA recombinases: A user's guide for conducting more precise cell fate mapping studies.
Volume: 295
Issue: 19
Pages: 6413-6424
Publication
First Author: Tata PR
Year: 2013
Journal: Nature
Title: Dedifferentiation of committed epithelial cells into stem cells in vivo.
Volume: 503
Issue: 7475
Pages: 218-23
Publication
First Author: Brusilovsky M
Year: 2021
Journal: Nat Immunol
Title: Environmental allergens trigger type 2 inflammation through ripoptosome activation.
Volume: 22
Issue: 10
Pages: 1316-1326
Publication
First Author: Zheng F
Year: 1999
Journal: Nat Med
Title: Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice.
Volume: 5
Issue: 9
Pages: 1018-25
Publication
First Author: Watson JK
Year: 2015
Journal: Cell Rep
Title: Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium.
Volume: 12
Issue: 1
Pages: 90-101
Publication
First Author: Chen H
Year: 2012
Journal: Stem Cells
Title: Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury.
Volume: 30
Issue: 9
Pages: 1948-60
Publication
First Author: Malvin NP
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Autophagy proteins are required for club cell structure and function in airways.
Volume: 317
Issue: 2
Pages: L259-L270
Publication
First Author: Lu Y
Year: 2010
Journal: PLoS One
Title: Evidence that SOX2 overexpression is oncogenic in the lung.
Volume: 5
Issue: 6
Pages: e11022
Publication
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
Publication
First Author: Rosigkeit S
Year: 2021
Journal: Int J Cancer
Title: Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer.
Volume: 149
Issue: 9
Pages: 1670-1682
Publication
First Author: Yee M
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.
Volume: 56
Issue: 4
Pages: 453-464
Publication  
First Author: Liu K
Year: 2020
Journal: Cell Discov
Title: Bi-directional differentiation of single bronchioalveolar stem cells during lung repair.
Volume: 6
Pages: 1
Publication  
First Author: Sponchiado M
Year: 2023
Journal: Front Physiol
Title: Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.
Volume: 14
Pages: 1323865
Publication
First Author: Akram KM
Year: 2018
Journal: Mucosal Immunol
Title: An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection.
Volume: 11
Issue: 1
Pages: 71-81
Publication  
First Author: Tien JC
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.
Volume: 118
Issue: 20
Publication  
First Author: Mao Y
Year: 2022
Journal: Front Immunol
Title: Airway epithelial cell-specific deletion of HMGB1 exaggerates inflammatory responses in mice with muco-obstructive airway disease.
Volume: 13
Pages: 944772
Publication
First Author: Zheng D
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Evidence for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma.
Volume: 50
Issue: 3
Pages: 595-604
Publication
First Author: Morris CR
Year: 2022
Journal: Mucosal Immunol
Title: Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease.
Volume: 15
Issue: 5
Pages: 977-989
Publication
First Author: Hsu YC
Year: 2011
Journal: Dev Biol
Title: Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation.
Volume: 354
Issue: 2
Pages: 242-52
Publication
First Author: Tian B
Year: 2018
Journal: Cell Rep
Title: Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation.
Volume: 23
Issue: 4
Pages: 1138-1151
Publication
First Author: De la Garza MM
Year: 2018
Journal: Oncotarget
Title: COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation.
Volume: 9
Issue: 68
Pages: 32972-32983
Publication  
First Author: Maier AM
Year: 2023
Journal: Front Immunol
Title: The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages.
Volume: 14
Pages: 1157373
Publication  
First Author: Xie T
Year: 2021
Journal: Sci Adv
Title: Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis.
Volume: 7
Issue: 24
Publication
First Author: Xu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
Volume: 109
Issue: 13
Pages: 4910-5
Publication
First Author: Teisanu RM
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.
Volume: 44
Issue: 6
Pages: 794-803
Publication
First Author: Moon HG
Year: 2018
Journal: Immunity
Title: Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization.
Volume: 49
Issue: 2
Pages: 275-287.e5
Publication
First Author: Byrd AL
Year: 2023
Journal: Stem Cell Reports
Title: Dysregulated Polycomb Repressive Complex 2 contributes to chronic obstructive pulmonary disease by rewiring stem cell fate.
Volume: 18
Issue: 1
Pages: 289-304
Publication
First Author: Baluk P
Year: 2020
Journal: Am J Pathol
Title: Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury.
Volume: 190
Issue: 12
Pages: 2355-2375
Publication
First Author: Piñeiro-Hermida S
Year: 2022
Journal: Nat Commun
Title: Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development.
Volume: 13
Issue: 1
Pages: 5656
Publication
First Author: Liu Q
Year: 2019
Journal: Nat Genet
Title: Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.
Volume: 51
Issue: 4
Pages: 728-738
Publication  
First Author: Salwig I
Year: 2019
Journal: EMBO J
Title: Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo.
Volume: 38
Issue: 12
Publication
First Author: Galvis LA
Year: 2015
Journal: Development
Title: Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung.
Volume: 142
Issue: 8
Pages: 1458-69
Publication
First Author: Ghosh B
Year: 2022
Journal: Commun Biol
Title: Loss of E-cadherin is causal to pathologic changes in chronic lung disease.
Volume: 5
Issue: 1
Pages: 1149
Publication
First Author: Khatri A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia.
Volume: 116
Issue: 5
Pages: 1603-1612
Publication
First Author: Liu K
Year: 2020
Journal: J Biol Chem
Title: Triple-cell lineage tracing by a dual reporter on a single allele.
Volume: 295
Issue: 3
Pages: 690-700
Publication
First Author: Barkauskas CE
Year: 2013
Journal: J Clin Invest
Title: Type 2 alveolar cells are stem cells in adult lung.
Volume: 123
Issue: 7
Pages: 3025-36
Publication
First Author: Lee JH
Year: 2017
Journal: Cell
Title: Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6.
Volume: 170
Issue: 6
Pages: 1149-1163.e12
Publication
First Author: Rock JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
Volume: 108
Issue: 52
Pages: E1475-83
Publication  
First Author: Tilston-Lunel A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
Volume: 118
Issue: 18
Publication
First Author: Vaughan AE
Year: 2015
Journal: Nature
Title: Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.
Volume: 517
Issue: 7536
Pages: 621-5
Publication    
First Author: Le Roux Ö
Year: 2022
Journal: Elife
Title: Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis.
Volume: 11
Publication  
First Author: Ah-Cann C
Year: 2021
Journal: Development
Title: A functional genetic screen identifies aurora kinase b as an essential regulator of Sox9-positive mouse embryonic lung progenitor cells.
Volume: 148
Issue: 13
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Margraf LR
Year: 1993
Journal: Am J Respir Cell Mol Biol
Title: Cloning and tissue-specific expression of the cDNA for the mouse Clara cell 10 kD protein: comparison of endogenous expression to rabbit uteroglobin promoter-driven transgene expression.
Volume: 9
Issue: 3
Pages: 231-8
Publication
First Author: Stripp BR
Year: 1994
Journal: Genomics
Title: Structure and regulation of the murine Clara cell secretory protein gene.
Volume: 20
Issue: 1
Pages: 27-35
Publication
First Author: Singh G
Year: 1993
Journal: Exp Lung Res
Title: Mouse Clara cell 10-kDa (CC10) protein: cDNA nucleotide sequence and molecular basis for the variation in progesterone binding of CC10 from different species.
Volume: 19
Issue: 1
Pages: 67-75
Publication
First Author: Ray MK
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Cloning and characterization of the mouse Clara cell specific 10 kDa protein gene: comparison of the 5'-flanking region with the human rat and rabbit gene.
Volume: 197
Issue: 1
Pages: 163-71
Publication
First Author: Stripp BR
Year: 1996
Journal: Am J Physiol
Title: Clara cell secretory protein: a determinant of PCB bioaccumulation in mammals.
Volume: 271
Issue: 4 Pt 1
Pages: L656-64
Publication
First Author: Reynolds SD
Year: 1999
Journal: Am J Kidney Dis
Title: Normal function and lack of fibronectin accumulation in kidneys of Clara cell secretory protein/uteroglobin deficient mice.
Volume: 33
Issue: 3
Pages: 541-51
Publication
First Author: Hayashida S
Year: 2000
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Regulation and function of CCSP during pulmonary Pseudomonas aeruginosa infection in vivo.
Volume: 279
Issue: 3
Pages: L452-9
Publication
First Author: Stripp BR
Year: 2002
Journal: Am J Respir Cell Mol Biol
Title: Clara cell secretory protein deficiency alters clara cell secretory apparatus and the protein composition of airway lining fluid.
Volume: 27
Issue: 2
Pages: 170-8
Publication
First Author: Mango GW
Year: 1998
Journal: Am J Physiol
Title: Clara cell secretory protein deficiency increases oxidant stress response in conducting airways.
Volume: 275
Issue: 2 Pt 1
Pages: L348-56
Publication
First Author: Watson TM
Year: 2001
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Altered lung gene expression in CCSP-null mice suggests immunoregulatory roles for Clara cells.
Volume: 281
Issue: 6
Pages: L1523-30
Publication
First Author: Laucho-Contreras ME
Year: 2015
Journal: Eur Respir J
Title: Protective role for club cell secretory protein-16 (CC16) in the development of COPD.
Volume: 45
Issue: 6
Pages: 1544-56
Publication
First Author: Wang SZ
Year: 2001
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model.
Volume: 281
Issue: 5
Pages: L1303-11
Publication
First Author: Johnston CJ
Year: 1999
Journal: Exp Lung Res
Title: Clara cell secretory protein-deficient mice differ from wild-type mice in inflammatory chemokine expression to oxygen and ozone, but not to endotoxin.
Volume: 25
Issue: 1
Pages: 7-21
Publication
First Author: Wendt C
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Club cell secretory protein improves survival in a murine obliterative bronchiolitis model.
Volume: 305
Issue: 9
Pages: L642-50