|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 70 out of 70 for Scgb1c1

0.021s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
147199 | SCGB1C1
Type: gene
Organism: human
•
•
•
•
•
Gene
309100 | Scgb1c1
Type: gene
Organism: rat
•
•
•
•
•
Gene
743443 | SCGB1C1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
606779 | SCGB1C1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
615894 | SCGB1C1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
696344 | SCGB1C1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:2655401 | Scgb1c1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0030660 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0033193 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0033175 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0033107 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0033176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0032890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_2655401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0033687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0032220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0032862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0033015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0032967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0033109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0033000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0033707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0031925 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0032331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0013860 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0031771 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
12406855 | J:82365
First Author: Reynolds SD
Year: 2002
Journal: Am J Respir Crit Care Med
Title: Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.
Volume: 166
Issue: 11
Pages: 1498-509
•
•
•
•
•
Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
•
•
•
•
•
Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
•
•
•
•
•
Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
•
•
•
•
•
Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Protein Domain
IPR043215 | Secretoglobin_1C-like
Type: Family
Description: Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity [, ]. Secretoglobin have a four-helical structure, and in the case of uteroglobin, form homodimers, whereas allergen Fel d 1 forms a tetramer of two heterodimers (chains 1 and 2). The conservation of this primary and quaternary structure indicates that the genome of the eutherian common ancestor of cats, rodents, and primates contained a similar gene pair.Uteroglobin (blastokinin or Clara cell protein CC10) is a mammalian steroid-inducible secreted protein originally isolated from the uterus of rabbits during early pregnancy []. The mucosal epithelia of several organs that communicate with the external environment express uteroglobin. Its tissue-specific expression is regulated by steroid hormones, and is augmented in the uterus by non-steroidal prolactin. Uteroglobin may be a multi-functional protein with anti-inflammatory/immunomodulatory properties, acting to inhibit phospholipase A2 activity [, ], and binding to (and possibly sequestering) several hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids and prostaglandins [, ]. In addition, uteroglobin has anti-chemotactic, anti-allergic, anti-tumourigenic and embryo growth-stimulatory properties. Uteroglobin may have a homeostatic role against oxidative damage, inflammation, autoimmunity and cancer [, , , ]. However, the true biological function of uteroglobin is poorly understood. Uteroglobin consists of a disulphide-linked homodimer with a large hydrophobic pocket located between the two dimers []. Each monomer being composed of four helices that do not form a canonical four helix-bundle motif but rather a boomerang-shaped structure in which helices H1, H3, and H4 are able to bind a homodimeric partner []. The hydrophobic pocket binds steroids, particularly progesterone, with high specificity. It is a member of the secretoglobin superfamily.This entry represents the uteroglobin and secretoglobin family 1C (SCGB1C). SCGB1C1 has been shown to be localised to Bowman's glands in the olfactory mucosa []. It is thought to act as an odorant-binding protein, with ligands appearing to be small, hydrophobic molecules [].
•
•
•
•
•
Publication
1915264 | -
First Author: Dear TN
Year: 1991
Journal: EMBO J
Title: Novel genes for potential ligand-binding proteins in subregions of the olfactory mucosa.
Volume: 10
Issue: 10
Pages: 2813-9
•
•
•
•
•
Publication
22155607 | J:185789
First Author: Jackson BC
Year: 2011
Journal: Hum Genomics
Title: Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily.
Volume: 5
Issue: 6
Pages: 691-702
•
•
•
•
•
Publication
7868811 | -
First Author: Miele L
Year: 1994
Journal: J Endocrinol Invest
Title: Uteroglobin and uteroglobin-like proteins: the uteroglobin family of proteins.
Volume: 17
Issue: 8
Pages: 679-92
•
•
•
•
•
Publication
11193777 | -
 
First Author: Klug J
Year: 2000
Journal: Ann N Y Acad Sci
Title: Uteroglobin/Clara cell 10-kDa family of proteins: nomenclature committee report.
Volume: 923
Pages: 348-54
•
•
•
•
•
Protein
Q7M742
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: false
•
•
•
•
•
Protein
Q06318
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: false
•
•
•
•
•
Protein
G5E8B5
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: false
•
•
•
•
•
Protein
Q3UKV9
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: false
•
•
•
•
•
Publication
7770456 | -
First Author: Dunkel R
Year: 1995
Journal: Protein Eng
Title: Progesterone binding to uteroglobin: two alternative orientations of the ligand.
Volume: 8
Issue: 1
Pages: 71-9
•
•
•
•
•
Publication
3656405 | -
First Author: Morize I
Year: 1987
Journal: J Mol Biol
Title: Refinement of the C222(1) crystal form of oxidized uteroglobin at 1.34 A resolution.
Volume: 194
Issue: 4
Pages: 725-39
•
•
•
•
•
Publication
17916741 | -
First Author: Mukherjee AB
Year: 2007
Journal: Endocr Rev
Title: Uteroglobin: a steroid-inducible immunomodulatory protein that founded the Secretoglobin superfamily.
Volume: 28
Issue: 7
Pages: 707-25
•
•
•
•
•
Publication
17928103 | -
First Author: Li C
Year: 2007
Journal: Peptides
Title: Interaction of antiflammin-1 with uteroglobin-binding protein induces phosphorylation of ERK1/2 in NIH 3T3 cells.
Volume: 28
Issue: 11
Pages: 2137-45
•
•
•
•
•
Publication
11193760 | -
 
First Author: Kundu GC
Year: 2000
Journal: Ann N Y Acad Sci
Title: Uteroglobin binding proteins: regulation of cellular motility and invasion in normal and cancer cells.
Volume: 923
Pages: 234-48
•
•
•
•
•
Publication
11193783 | -
 
First Author: Callebaut I
Year: 2000
Journal: Ann N Y Acad Sci
Title: The uteroglobin fold.
Volume: 923
Pages: 90-112
•
•
•
•
•
Publication
2378892 | -
First Author: Singh G
Year: 1990
Journal: Biochim Biophys Acta
Title: Clara cell 10 kDa protein (CC10): comparison of structure and function to uteroglobin.
Volume: 1039
Issue: 3
Pages: 348-55
•
•
•
•
•
Publication
3319534 | -
First Author: Miele L
Year: 1987
Journal: Endocr Rev
Title: Uteroglobin: structure, molecular biology, and new perspectives on its function as a phospholipase A2 inhibitor.
Volume: 8
Issue: 4
Pages: 474-90
•
•
•
•
•
Publication
11193782 | -
 
First Author: Beier HM
Year: 2000
Journal: Ann N Y Acad Sci
Title: The discovery of uteroglobin and its significance for reproductive biology and endocrinology.
Volume: 923
Pages: 9-24
•
•
•
•
•
Publication
11193767 | -
 
First Author: Chowdhury B
Year: 2000
Journal: Ann N Y Acad Sci
Title: Amino acid residues in alpha-helix-3 of human uteroglobin are critical for its phospholipase A2 inhibitory activity.
Volume: 923
Pages: 307-11
•
•
•
•
•
Publication
11193750 | -
 
First Author: Pattabiraman N
Year: 2000
Journal: Ann N Y Acad Sci
Title: Crystal structure analysis of recombinant human uteroglobin and molecular modeling of ligand binding.
Volume: 923
Pages: 113-27
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom