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Search results 1 to 100 out of 272 for Scn10a

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0.083s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Chambers JC
Year: 2010
Journal: Nat Genet
Title: Genetic variation in SCN10A influences cardiac conduction.
Volume: 42
Issue: 2
Pages: 149-52
Publication
First Author: Persson AK
Year: 2013
Journal: J Neurosci
Title: Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury.
Volume: 33
Issue: 49
Pages: 19250-61
Publication
First Author: Stirling LC
Year: 2005
Journal: Pain
Title: Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice.
Volume: 113
Issue: 1-2
Pages: 27-36
Publication
First Author: Zhao J
Year: 2006
Journal: Genesis
Title: Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia.
Volume: 44
Issue: 8
Pages: 364-71
Publication
First Author: Gautron L
Year: 2011
Journal: J Comp Neurol
Title: Genetic tracing of Nav1.8-expressing vagal afferents in the mouse.
Volume: 519
Issue: 15
Pages: 3085-101
Publication  
First Author: Thakur M
Year: 2014
Journal: Front Mol Neurosci
Title: Defining the nociceptor transcriptome.
Volume: 7
Pages: 87
Publication
First Author: Daou I
Year: 2013
Journal: J Neurosci
Title: Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
Volume: 33
Issue: 47
Pages: 18631-40
Publication  
First Author: Daou I
Year: 2016
Journal: eNeuro
Title: Optogenetic Silencing of Nav1.8-Positive Afferents Alleviates Inflammatory and Neuropathic Pain.
Volume: 3
Issue: 1
Publication      
First Author: Megat S
Year: 2019
Journal: J Neurosci
Title: Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling.
Publication
First Author: Emery EC
Year: 2011
Journal: Science
Title: HCN2 ion channels play a central role in inflammatory and neuropathic pain.
Volume: 333
Issue: 6048
Pages: 1462-6
Publication
First Author: Shields SD
Year: 2012
Journal: J Neurosci
Title: Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury.
Volume: 32
Issue: 32
Pages: 10819-32
Publication  
First Author: Yuan X
Year: 2016
Journal: eNeuro
Title: Levels of Cocaine- and Amphetamine-Regulated Transcript in Vagal Afferents in the Mouse Are Unaltered in Response to Metabolic Challenges.
Volume: 3
Issue: 5
Publication
First Author: Zhao J
Year: 2006
Journal: Mol Cell Neurosci
Title: Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain.
Volume: 31
Issue: 3
Pages: 539-48
Publication
First Author: Gaveriaux-Ruff C
Year: 2011
Journal: Pain
Title: Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia.
Volume: 152
Issue: 6
Pages: 1238-48
Publication
First Author: de Lartigue G
Year: 2014
Journal: Mol Metab
Title: Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity.
Volume: 3
Issue: 6
Pages: 595-607
Publication
First Author: Nassar MA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain.
Volume: 101
Issue: 34
Pages: 12706-11
Publication  
First Author: Zhao J
Year: 2010
Journal: Mol Pain
Title: Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain.
Volume: 6
Pages: 77
Publication
First Author: Foulkes T
Year: 2006
Journal: J Neurosci
Title: Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.
Volume: 26
Issue: 41
Pages: 10499-507
Publication  
First Author: Nassar MA
Year: 2006
Journal: Mol Pain
Title: Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.
Volume: 2
Pages: 33
Publication
First Author: Abrahamsen B
Year: 2008
Journal: Science
Title: The cell and molecular basis of mechanical, cold, and inflammatory pain.
Volume: 321
Issue: 5889
Pages: 702-5
Publication
First Author: Shields SD
Year: 2012
Journal: Pain
Title: Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system.
Volume: 153
Issue: 10
Pages: 2017-30
Publication
First Author: Chen L
Year: 2018
Journal: Sci Rep
Title: Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain.
Volume: 8
Issue: 1
Pages: 3845
Publication
First Author: Takahashi S
Year: 2019
Journal: Sci Rep
Title: Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development.
Volume: 9
Issue: 1
Pages: 8625
Publication
First Author: Weibel R
Year: 2013
Journal: PLoS One
Title: Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice.
Volume: 8
Issue: 9
Pages: e74706
Publication
First Author: Crow M
Year: 2015
Journal: FASEB J
Title: HDAC4 is required for inflammation-associated thermal hypersensitivity.
Volume: 29
Issue: 8
Pages: 3370-8
Publication
First Author: Sorge RE
Year: 2013
Journal: Genes Brain Behav
Title: The Yin and Yang of pain: variability in formalin test nociception and morphine analgesia produced by the Yin Yang 1 transcription factor gene.
Volume: 12
Issue: 4
Pages: 405-13
Publication
First Author: Han Q
Year: 2016
Journal: Neuron
Title: SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons.
Volume: 92
Issue: 6
Pages: 1279-1293
Publication
First Author: Zhao J
Year: 2010
Journal: J Neurosci
Title: Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.
Volume: 30
Issue: 32
Pages: 10860-71
Publication
First Author: Fricker FR
Year: 2009
Journal: J Neurosci
Title: Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.
Volume: 29
Issue: 24
Pages: 7667-78
Publication
First Author: Fong SW
Year: 2016
Journal: PLoS One
Title: CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation.
Volume: 11
Issue: 2
Pages: e0148491
Publication
First Author: Eijkelkamp N
Year: 2010
Journal: J Neurosci
Title: GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain.
Volume: 30
Issue: 6
Pages: 2138-49
Publication  
First Author: Wu WL
Year: 2019
Journal: Front Cell Neurosci
Title: The Effect of ASIC3 Knockout on Corticostriatal Circuit and Mouse Self-grooming Behavior.
Volume: 13
Pages: 86
Publication  
First Author: Ding J
Year: 2014
Journal: Behav Brain Res
Title: Deletion of KCC3 in parvalbumin neurons leads to locomotor deficit in a conditional mouse model of peripheral neuropathy associated with agenesis of the corpus callosum.
Volume: 274
Pages: 128-36
Publication
First Author: Megat S
Year: 2019
Journal: J Neurosci
Title: Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain.
Volume: 39
Issue: 3
Pages: 393-411
Publication
First Author: Gavini CK
Year: 2018
Journal: Cell Rep
Title: Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia.
Volume: 25
Issue: 2
Pages: 271-277.e4
Publication
First Author: Yu YQ
Year: 2017
Journal: Science
Title: Molecular and neural basis of contagious itch behavior in mice.
Volume: 355
Issue: 6329
Pages: 1072-1076
Publication
First Author: Lagerström MC
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain.
Volume: 108
Issue: 14
Pages: 5789-94
Publication
First Author: Willemen HL
Year: 2010
Journal: Pain
Title: Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.
Volume: 150
Issue: 3
Pages: 550-60
Publication
First Author: Eijkelkamp N
Year: 2010
Journal: J Neurosci
Title: Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK.
Volume: 30
Issue: 38
Pages: 12806-15
Publication
First Author: Zhao ZQ
Year: 2013
Journal: J Clin Invest
Title: Chronic itch development in sensory neurons requires BRAF signaling pathways.
Volume: 123
Issue: 11
Pages: 4769-80
Publication  
First Author: Minett MS
Year: 2012
Journal: Nat Commun
Title: Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.
Volume: 3
Pages: 791
Publication    
First Author: Mansuy-Aubert V
Year: 2015
Journal: Elife
Title: Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure.
Volume: 4
Publication
First Author: Lin SH
Year: 2017
Journal: J Invest Dermatol
Title: Involvement of TRPV1 and TDAG8 in Pruriception Associated with Noxious Acidosis.
Volume: 137
Issue: 1
Pages: 170-178
Publication
First Author: Zhao ZQ
Year: 2014
Journal: Neuron
Title: Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signaling.
Volume: 84
Issue: 4
Pages: 821-34
Publication
First Author: Lagerström MC
Year: 2010
Journal: Neuron
Title: VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch.
Volume: 68
Issue: 3
Pages: 529-42
Publication
First Author: Minett MS
Year: 2014
Journal: Cell Rep
Title: Pain without nociceptors? Nav1.7-independent pain mechanisms.
Volume: 6
Issue: 2
Pages: 301-12
Publication    
First Author: Barry DM
Year: 2016
Journal: Mol Pain
Title: Critical evaluation of the expression of gastrin-releasing peptide in dorsal root ganglia and spinal cord.
Volume: 12
Publication
First Author: Zhang Q
Year: 2019
Journal: Nat Neurosci
Title: Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.
Volume: 22
Issue: 5
Pages: 828-839
Publication
First Author: Minett MS
Year: 2014
Journal: PLoS One
Title: Significant determinants of mouse pain behaviour.
Volume: 9
Issue: 8
Pages: e104458
Publication
First Author: Riol-Blanco L
Year: 2014
Journal: Nature
Title: Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.
Volume: 510
Issue: 7503
Pages: 157-61
Publication  
First Author: Lin SH
Year: 2016
Journal: Nat Commun
Title: Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors.
Volume: 7
Pages: 11460
Publication
First Author: Maruyama K
Year: 2017
Journal: Cell Rep
Title: Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis.
Volume: 19
Issue: 13
Pages: 2730-2742
Publication
First Author: Huang CC
Year: 2018
Journal: Nat Med
Title: Anatomical and functional dichotomy of ocular itch and pain.
Volume: 24
Issue: 8
Pages: 1268-1276
Publication
First Author: Munanairi A
Year: 2018
Journal: Cell Rep
Title: Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal Cord of Mice.
Volume: 23
Issue: 3
Pages: 866-877
Publication  
First Author: Ren AJ
Year: 2014
Journal: Nat Commun
Title: ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.
Volume: 5
Pages: 4984
Publication
First Author: Wickramasinghe SR
Year: 2008
Journal: Neuron
Title: Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons.
Volume: 58
Issue: 4
Pages: 532-45
Publication
First Author: van den Boogaard M
Year: 2014
Journal: J Clin Invest
Title: A common genetic variant within SCN10A modulates cardiac SCN5A expression.
Volume: 124
Issue: 4
Pages: 1844-52
Publication
First Author: Yang T
Year: 2012
Journal: Circ Res
Title: Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Volume: 111
Issue: 3
Pages: 322-32
Publication
First Author: Blasius AL
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.
Volume: 108
Issue: 48
Pages: 19413-8
Publication
First Author: Verkerk AO
Year: 2012
Journal: Circ Res
Title: Functional Nav1.8 channels in intracardiac neurons: the link between SCN10A and cardiac electrophysiology.
Volume: 111
Issue: 3
Pages: 333-43
Publication
First Author: Rannals MD
Year: 2016
Journal: Neuron
Title: Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1.
Volume: 90
Issue: 1
Pages: 43-55
Publication
First Author: van den Boogaard M
Year: 2012
Journal: J Clin Invest
Title: Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
Volume: 122
Issue: 7
Pages: 2519-30
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Souslova VA
Year: 1997
Journal: Genomics
Title: Cloning and characterization of a mouse sensory neuron tetrodotoxin-resistant voltage-gated sodium channel gene, Scn10a.
Volume: 41
Issue: 2
Pages: 201-9
Publication
First Author: Akopian AN
Year: 1999
Journal: Nat Neurosci
Title: The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways.
Volume: 2
Issue: 6
Pages: 541-8
Publication
First Author: Kerr BJ
Year: 2001
Journal: Neuroreport
Title: A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain.
Volume: 12
Issue: 14
Pages: 3077-80
Publication  
First Author: Moldovan M
Year: 2016
Journal: Neurobiol Aging
Title: Aging-associated changes in motor axon voltage-gated Na(+) channel function in mice.
Volume: 39
Pages: 128-39
Publication
First Author: Laird JM
Year: 2002
Journal: J Neurosci
Title: Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice.
Volume: 22
Issue: 19
Pages: 8352-6
Publication
First Author: Roza C
Year: 2003
Journal: J Physiol
Title: The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice.
Volume: 550
Issue: Pt 3
Pages: 921-6
Publication
First Author: Renganathan M
Year: 2001
Journal: J Neurophysiol
Title: Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons.
Volume: 86
Issue: 2
Pages: 629-40
Publication
First Author: Renganathan M
Year: 2000
Journal: J Neurophysiol
Title: alpha-SNS produces the slow TTX-resistant sodium current in large cutaneous afferent DRG neurons.
Volume: 84
Issue: 2
Pages: 710-8
Publication
First Author: Zimmermann K
Year: 2007
Journal: Nature
Title: Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures.
Volume: 447
Issue: 7146
Pages: 855-8
Publication
First Author: Garrison SR
Year: 2014
Journal: Pain
Title: A gain-of-function voltage-gated sodium channel 1.8 mutation drives intense hyperexcitability of A- and C-fiber neurons.
Volume: 155
Issue: 5
Pages: 896-905
Publication
First Author: Huang J
Year: 2013
Journal: J Neurosci
Title: Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.
Volume: 33
Issue: 35
Pages: 14087-97
GXD Expression      
Probe: MGI:3707870
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3708955
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3707870
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3708955
Age: postnatal day 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3707870
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:3708955
Age: embryonic day 17.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4422473
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827900
Age: embryonic day 14.5
Image: euxassay_007406_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4422473
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827900
Age: embryonic day 14.5
Image: euxassay_007406_14
Detected: true
Specimen Num: 12