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Search results 1 to 100 out of 421 for Scn10a

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Hits by Category

Hits by Strain

Type Details Score
Gene
6336 | SCN10A
Type: gene
Organism: human
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Gene
29571 | Scn10a
Type: gene
Organism: rat
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Gene
477026 | SCN10A
Type: gene
Organism: dog, domestic
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Gene
460274 | SCN10A
Type: gene
Organism: chimpanzee
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Gene
100299477 | SCN10A
Type: gene
Organism: cattle
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Gene
694962 | SCN10A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:108029 | Scn10a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20062061 | J:166572
First Author: Chambers JC
Year: 2010
Journal: Nat Genet
Title: Genetic variation in SCN10A influences cardiac conduction.
Volume: 42
Issue: 2
Pages: 149-52
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Publication
24642470 | J:209588
First Author: van den Boogaard M
Year: 2014
Journal: J Clin Invest
Title: A common genetic variant within SCN10A modulates cardiac SCN5A expression.
Volume: 124
Issue: 4
Pages: 1844-52
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Publication
22723299 | J:212890
First Author: Yang T
Year: 2012
Journal: Circ Res
Title: Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Volume: 111
Issue: 3
Pages: 322-32
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Publication
25995484 | J:220881
First Author: Lu VB
Year: 2015
Journal: J Neurosci
Title: A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal.
Volume: 35
Issue: 20
Pages: 8021-34
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Publication
36816616 | J:365793
 
First Author: Mouchbahani-Constance S
Year: 2023
Journal: Neurobiol Pain
Title: Modulating the activity of human nociceptors with a SCN10A promoter-specific viral vector tool.
Volume: 13
Pages: 100120
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Publication
22723301 | J:212888
First Author: Verkerk AO
Year: 2012
Journal: Circ Res
Title: Functional Nav1.8 channels in intracardiac neurons: the link between SCN10A and cardiac electrophysiology.
Volume: 111
Issue: 3
Pages: 333-43
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Publication
22087007 | J:180381
First Author: Blasius AL
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.
Volume: 108
Issue: 48
Pages: 19413-8
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Publication
26971948 | J:239349
First Author: Rannals MD
Year: 2016
Journal: Neuron
Title: Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1.
Volume: 90
Issue: 1
Pages: 43-55
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GXD Expression
GXD Expression
     
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191256
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Scn10a
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191256
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Scn10a
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191256
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Scn10a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191256
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Scn10a
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191256
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Scn10a
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191256
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Scn10a
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6182845
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191256
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Scn10a
Detected: true
Specimen Num: 7
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Publication
38510134 | J:353246
First Author: Malapert P
Year: 2024
Journal: iScience
Title: A novel Na(v)1.8-FLPo driver mouse for intersectional genetics to uncover the functional significance of primary sensory neuron diversity.
Volume: 27
Issue: 4
Pages: 109396
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Publication
34925037 | J:342722
 
First Author: Chidiac C
Year: 2021
Journal: Front Pharmacol
Title: The Human SCN10A(G1662S) Point Mutation Established in Mice Impacts on Mechanical, Heat, and Cool Sensitivity.
Volume: 12
Pages: 780132
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Publication
41015152 | J:374721
 
First Author: Bethea M
Year: 2025
Journal: Mol Metab
Title: Weight loss reverses obesity-associated impairments in acute gastrointestinal stretch-induced suppression of food intake and glucose homeostasis.
Volume: 102
Pages: 102260
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Publication
22706305 | J:190769
First Author: van den Boogaard M
Year: 2012
Journal: J Clin Invest
Title: Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
Volume: 122
Issue: 7
Pages: 2519-30
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Publication
34043943 | J:314805
First Author: Borgmann D
Year: 2021
Journal: Cell Metab
Title: Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism.
Volume: 33
Issue: 7
Pages: 1466-1482.e7
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Protein Coding Gene
MGP_CAROLIEiJ_G0032804 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200030341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195027080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220017695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180029360 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175018701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_108029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215029134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005016106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210031341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185016033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205014041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230032471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000023647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190013234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225023475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010032342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005020070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015671 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010022047 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9143495 | J:39874
First Author: Souslova VA
Year: 1997
Journal: Genomics
Title: Cloning and characterization of a mouse sensory neuron tetrodotoxin-resistant voltage-gated sodium channel gene, Scn10a.
Volume: 41
Issue: 2
Pages: 201-9
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Publication
15048809 | J:89764
First Author: Agarwal N
Year: 2004
Journal: Genesis
Title: Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia.
Volume: 38
Issue: 3
Pages: 122-9
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Publication
16850455 | J:114488
First Author: Zhao J
Year: 2006
Journal: Genesis
Title: Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia.
Volume: 44
Issue: 8
Pages: 364-71
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Publication
10448219 | J:76456
First Author: Akopian AN
Year: 1999
Journal: Nat Neurosci
Title: The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways.
Volume: 2
Issue: 6
Pages: 541-8
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Publication
12824446 | J:105561
First Author: Roza C
Year: 2003
Journal: J Physiol
Title: The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice.
Volume: 550
Issue: Pt 3
Pages: 921-6
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Publication
34782600 | J:322051
First Author: Bengel P
Year: 2021
Journal: Nat Commun
Title: Detrimental proarrhythmogenic interaction of Ca(2+)/calmodulin-dependent protein kinase II and Na(V)1.8 in heart failure.
Volume: 12
Issue: 1
Pages: 6586
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Publication
12351708 | J:79211
First Author: Laird JM
Year: 2002
Journal: J Neurosci
Title: Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice.
Volume: 22
Issue: 19
Pages: 8352-6
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Publication
37378314 | J:388948
First Author: Liu B
Year: 2023
Journal: iScience
Title: A novel co-target of ACY1 governing plasma membrane translocation of SphK1 contributes to inflammatory and neuropathic pain.
Volume: 26
Issue: 6
Pages: 106989
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Publication
10938298 | J:103971
First Author: Renganathan M
Year: 2000
Journal: J Neurophysiol
Title: alpha-SNS produces the slow TTX-resistant sodium current in large cutaneous afferent DRG neurons.
Volume: 84
Issue: 2
Pages: 710-8
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Publication
32418916 | J:292745
 
First Author: Bengel P
Year: 2020
Journal: J Mol Cell Cardiol
Title: Contribution of the neuronal sodium channel Na(V)1.8 to sodium- and calcium-dependent cellular proarrhythmia.
Volume: 144
Pages: 35-46
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Publication
11568640 | J:103723
First Author: Kerr BJ
Year: 2001
Journal: Neuroreport
Title: A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain.
Volume: 12
Issue: 14
Pages: 3077-80
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Publication
11495938 | J:103963
First Author: Renganathan M
Year: 2001
Journal: J Neurophysiol
Title: Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons.
Volume: 86
Issue: 2
Pages: 629-40
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Publication
17568746 | J:122740
First Author: Zimmermann K
Year: 2007
Journal: Nature
Title: Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures.
Volume: 447
Issue: 7146
Pages: 855-8
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Publication
26923409 | J:234507
 
First Author: Moldovan M
Year: 2016
Journal: Neurobiol Aging
Title: Aging-associated changes in motor axon voltage-gated Na(+) channel function in mice.
Volume: 39
Pages: 128-39
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Publication
34006861 | J:321713
First Author: Filtjens J
Year: 2021
Journal: Nat Commun
Title: Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection.
Volume: 12
Issue: 1
Pages: 2936
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Publication
16157274 | J:100993
First Author: Braz JM
Year: 2005
Journal: Neuron
Title: Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor.
Volume: 47
Issue: 6
Pages: 787-93
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Publication
24305821 | J:204150
First Author: Persson AK
Year: 2013
Journal: J Neurosci
Title: Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury.
Volume: 33
Issue: 49
Pages: 19250-61
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Publication
27022626 | J:240235
 
First Author: Daou I
Year: 2016
Journal: eNeuro
Title: Optogenetic Silencing of Nav1.8-Positive Afferents Alleviates Inflammatory and Neuropathic Pain.
Volume: 3
Issue: 1
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Publication
38038153 | J:360180
First Author: Roman?-P?rez M
Year: 2024
Journal: Mol Nutr Food Res
Title: The Ablation of Sensory Neurons Expressing the Nav1.8 Sodium Channel Improves Glucose Homeostasis and Amplifies the GLP-1 Signaling in Obese Female Mice.
Volume: 68
Issue: 3
Pages: e2300474
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Publication
41779615 | J:386482
First Author: Wan S
Year: 2026
Journal: STAR Protoc
Title: Protocol for the precise activation of intradental neurons in mice via electrical stimulation.
Volume: 7
Issue: 1
Pages: 104386
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Publication
24259584 | J:204159
First Author: Daou I
Year: 2013
Journal: J Neurosci
Title: Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
Volume: 33
Issue: 47
Pages: 18631-40
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Publication
31253755 | J:276580
First Author: Megat S
Year: 2019
Journal: J Neurosci
Title: Differences between Dorsal Root and Trigeminal Ganglion Nociceptors in Mice Revealed by Translational Profiling.
Volume: 39
Issue: 35
Pages: 6829-6847
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Publication
15621361 | J:99609
First Author: Stirling LC
Year: 2005
Journal: Pain
Title: Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice.
Volume: 113
Issue: 1-2
Pages: 27-36
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Publication
36384109 | J:365660
First Author: Blaeser AS
Year: 2022
Journal: Cell Rep
Title: Trigeminal afferents sense locomotion-related meningeal deformations.
Volume: 41
Issue: 7
Pages: 111648
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Publication
29031710 | J:341486
First Author: Udit S
Year: 2017
Journal: Mol Metab
Title: Na(v)1.8 neurons are involved in limiting acute phase responses to dietary fat.
Volume: 6
Issue: 10
Pages: 1081-1091
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Publication
42786189 | J:393182
First Author: Hwang S
Year: 2026
Journal: Exp Mol Med
Title: Breath volatiles reflect diabetic gastroparesis and its recovery by activating Na(v)1.8-expressing neurons in mice.
Volume: 58
Issue: 9
Pages: 3214-3225
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Publication
34585109 | J:350605
First Author: Borah BJ
Year: 2021
Journal: iScience
Title: Nyquist-exceeding high voxel rate acquisition in mesoscopic multiphoton microscopy for full-field submicron resolution resolvability.
Volume: 24
Issue: 9
Pages: 103041
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Publication
25426020 | J:268826
 
First Author: Thakur M
Year: 2014
Journal: Front Mol Neurosci
Title: Defining the nociceptor transcriptome.
Volume: 7
Pages: 87
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Publication
31618460 | J:290156
First Author: Serlin HK
Year: 2020
Journal: J Comp Neurol
Title: Abdominal vagotomy reveals majority of small intestinal mucosal afferents labeled in na(v) 1.8cre-rosa26tdTomato mice are vagal in origin.
Volume: 528
Issue: 5
Pages: 816-839
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Publication
42208499 | J:387456
First Author: de S?? KSG
Year: 2026
Journal: Cell
Title: A causal link between autoantibodies and neurological symptoms in long COVID.
Volume: 189
Issue: 11
Pages: 3214-3235.e37
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Publication
35382899 | J:377896
First Author: Crosson T
Year: 2022
Journal: Bioelectron Med
Title: Anatomical differences in nociceptor neurons sensitivity.
Volume: 8
Issue: 1
Pages: 7
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Publication
40714297 | J:370643
 
First Author: Gupta N
Year: 2025
Journal: Ocul Surf
Title: New insight into the neuroimmune interplay in Pseudomonas aeruginosa keratitis.
Volume: 38
Pages: 170-183
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Publication
38388698 | J:346634
First Author: Bullich-Vilarrubias C
Year: 2024
Journal: Commun Biol
Title: Nav1.8-expressing neurons control daily oscillations of food intake, body weight and gut microbiota in mice.
Volume: 7
Issue: 1
Pages: 219
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Publication
34787642 | J:320960
First Author: Mecum NE
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Optogenetic Inhibition of Nav1.8 Expressing Corneal Afferents Reduces Persistent Dry Eye Pain.
Volume: 62
Issue: 14
Pages: 15
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Publication
33333021 | J:301487
First Author: Huang S
Year: 2021
Journal: Cell
Title: Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential.
Volume: 184
Issue: 2
Pages: 441-459.e25
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Publication
39256039 | J:365546
 
First Author: Hung ??? WC
Year: 2024
Journal: eNeuro
Title: Presynaptic Enhancement of Transmission from Nociceptors Expressing Nav1.8 onto Lamina-I Spinothalamic Tract Neurons by Spared Nerve Injury in Mice.
Volume: 11
Issue: 9
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Publication
38293826 | J:377664
First Author: Higham JP
Year: 2024
Journal: Pain
Title: Transcriptomic profiling reveals a pronociceptive role for angiotensin II in inflammatory bowel disease.
Volume: 165
Issue: 7
Pages: 1592-1604
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Publication
21618224 | J:196043
First Author: Gautron L
Year: 2011
Journal: J Comp Neurol
Title: Genetic tracing of Nav1.8-expressing vagal afferents in the mouse.
Volume: 519
Issue: 15
Pages: 3085-101
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Publication
37845223 | J:344077
First Author: Lillis KV
Year: 2023
Journal: Sci Rep
Title: Nociceptors regulate osteoimmune transcriptomic response to infection.
Volume: 13
Issue: 1
Pages: 17601
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Publication
34784974 | J:316168
First Author: Costa PAC
Year: 2021
Journal: Acta Neuropathol Commun
Title: Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression.
Volume: 9
Issue: 1
Pages: 183
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Publication
33057056 | J:299039
First Author: Mecum NE
Year: 2020
Journal: Sci Rep
Title: Lacrimal gland excision in male and female mice causes ocular pain and anxiety-like behaviors.
Volume: 10
Issue: 1
Pages: 17225
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Publication
35240196 | J:377679
 
First Author: Sullivan C
Year: 2022
Journal: Exp Eye Res
Title: Evidence for a phenotypic switch in corneal afferents after lacrimal gland excision.
Volume: 218
Pages: 109005
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Publication
22367990 | J:377687
First Author: Shields SD
Year: 2012
Journal: Ann Neurol
Title: A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis.
Volume: 71
Issue: 2
Pages: 186-94
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Publication
32691511 | J:332734
First Author: Prazeres PHDM
Year: 2020
Journal: J Cell Mol Med
Title: Ablation of sensory nerves favours melanoma progression.
Volume: 24
Issue: 17
Pages: 9574-9589
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Publication
24447515 | J:223498
First Author: Garrison SR
Year: 2014
Journal: Pain
Title: A gain-of-function voltage-gated sodium channel 1.8 mutation drives intense hyperexcitability of A- and C-fiber neurons.
Volume: 155
Issue: 5
Pages: 896-905
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Publication
22581285 | J:187460
First Author: Bierhaus A
Year: 2012
Journal: Nat Med
Title: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.
Volume: 18
Issue: 6
Pages: 926-33
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Publication
23986244 | J:201576
First Author: Huang J
Year: 2013
Journal: J Neurosci
Title: Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.
Volume: 33
Issue: 35
Pages: 14087-97
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Publication
32441256 | J:290217
   
First Author: Zhu J
Year: 2020
Journal: Elife
Title: Aberrant subchondral osteoblastic metabolism modifies Na(V)1.8 for osteoarthritis.
Volume: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3707870
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:3708955
Age: embryonic day 17.5
Specimen Label: Fetus
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3707870
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3708955
Age: postnatal day 1
Specimen Label: Neonate
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3707870
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3708955
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7258004
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667828
Stage: TS28
Assay Id: MGI:7258094
Age: postnatal month 2
Image: 5
Specimen Label: Lrig1+/+;Lrig3+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7258004
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667828
Stage: TS28
Assay Id: MGI:7258094
Age: postnatal month 2
Image: 5
Specimen Label: Lrig1+/-;Lrig3-/-
Detected: true
Specimen Num: 2
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