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Search results 1 to 100 out of 241 for Scn9a

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0.063s
Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: rabbit, European
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
First Author: Koenig J
Year: 2015
Journal: PLoS One
Title: Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.
Volume: 10
Issue: 6
Pages: e0128830
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Publication
First Author: Zhang Q
Year: 2014
Journal: J Physiol
Title: Na+ current properties in islet ?- and ?-cells reflect cell-specific Scn3a and Scn9a expression.
Volume: 592
Issue: 21
Pages: 4677-96
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Publication  
First Author: Xue Y
Year: 2022
Journal: Front Mol Neurosci
Title: The Human SCN9A (R185H) Point Mutation Induces Pain Hypersensitivity and Spontaneous Pain in Mice.
Volume: 15
Pages: 913990
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Gene
Type: gene
Organism: human
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Publication
First Author: Kozak CA
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.
Volume: 7
Issue: 10
Pages: 787-8
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Publication
First Author: Singh NA
Year: 2009
Journal: PLoS Genet
Title: A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome.
Volume: 5
Issue: 9
Pages: e1000649
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Publication
First Author: Maruta T
Year: 2022
Journal: PLoS One
Title: Selective optogenetic activation of NaV1.7-expressing afferents in NaV1.7-ChR2 mice induces nocifensive behavior without affecting responses to mechanical and thermal stimuli.
Volume: 17
Issue: 10
Pages: e0275751
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Publication
First Author: Branco T
Year: 2016
Journal: Cell
Title: Near-Perfect Synaptic Integration by Nav1.7 in Hypothalamic Neurons Regulates Body Weight.
Volume: 165
Issue: 7
Pages: 1749-1761
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Publication
First Author: Beckers MC
Year: 1996
Journal: Genomics
Title: A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.
Volume: 36
Issue: 1
Pages: 202-5
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Publication
First Author: Weiss J
Year: 2011
Journal: Nature
Title: Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.
Volume: 472
Issue: 7342
Pages: 186-90
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Publication  
First Author: Minett MS
Year: 2015
Journal: Nat Commun
Title: Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7.
Volume: 6
Pages: 8967
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Publication  
First Author: Minett MS
Year: 2012
Journal: Nat Commun
Title: Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.
Volume: 3
Pages: 791
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Publication
First Author: Soriano S
Year: 2019
Journal: Sci Rep
Title: Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception.
Volume: 9
Issue: 1
Pages: 10306
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Publication
First Author: Deng L
Year: 2023
Journal: Neuron
Title: Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids.
Volume: 111
Issue: 17
Pages: 2642-2659.e13
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Publication
First Author: Maruta T
Year: 2024
Journal: J Neurosci Res
Title: Comparison of Nocifensive Behavior in Na(V)1.7-, Na(V)1.8-, and Na(V)1.9-Channelrhodopsin-2 Mice by Selective Optogenetic Activation of Targeted Sodium Channel Subtype-Expressing Afferents.
Volume: 102
Issue: 10
Pages: e25386
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Publication
First Author: Shields SD
Year: 2018
Journal: J Neurosci
Title: Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors.
Volume: 38
Issue: 47
Pages: 10180-10201
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Publication
First Author: Kokotovi? T
Year: 2022
Journal: FEBS J
Title: Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function.
Volume: 289
Issue: 12
Pages: 3457-3476
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Publication  
First Author: Pereira V
Year: 2018
Journal: Wellcome Open Res
Title: Analgesia linked to Nav1.7 loss of function requires ?- and ?-opioid receptors.
Volume: 3
Pages: 101
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Allele  
Name: sodium channel, voltage-gated, type IX, alpha; endonuclease-mediated mutation 1, David H Hackos
Allele Type: Endonuclease-mediated
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication
First Author: Chen L
Year: 2021
Journal: Pain
Title: Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype.
Volume: 162
Issue: 6
Pages: 1758-1770
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Publication
First Author: Alles SRA
Year: 2020
Journal: Sci Adv
Title: Sensory neuron-derived Na(V)1.7 contributes to dorsal horn neuron excitability.
Volume: 6
Issue: 8
Pages: eaax4568
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Publication
First Author: Gingras J
Year: 2014
Journal: PLoS One
Title: Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain.
Volume: 9
Issue: 9
Pages: e105895
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Publication
First Author: Wimalasena NK
Year: 2021
Journal: Neuron
Title: Dissecting the precise nature of itch-evoked scratching.
Volume: 109
Issue: 19
Pages: 3075-3087.e2
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Publication
First Author: D'Arcangelo G
Year: 1993
Journal: J Cell Biol
Title: Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways.
Volume: 122
Issue: 4
Pages: 915-21
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Publication
First Author: McCormack K
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
Volume: 110
Issue: 29
Pages: E2724-32
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Publication
First Author: Yang S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models.
Volume: 110
Issue: 43
Pages: 17534-9
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Publication
First Author: Bankar G
Year: 2018
Journal: Cell Rep
Title: Selective Na(V)1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain.
Volume: 24
Issue: 12
Pages: 3133-3145
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: brain - total
Detected: true
Specimen Num: 1
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: cortex
Detected: true
Specimen Num: 2
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755028
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: brain medulla
Detected: true
Specimen Num: 3
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: cerebellum
Detected: true
Specimen Num: 4
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: brainstem
Detected: true
Specimen Num: 5
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: olfactory bulb
Detected: true
Specimen Num: 6
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: spinal cord
Detected: true
Specimen Num: 7
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: eye
Detected: true
Specimen Num: 8
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915328
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: harderian gland
Detected: true
Specimen Num: 9
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: heart
Detected: true
Specimen Num: 10
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: lung
Detected: false
Specimen Num: 11
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: liver
Detected: false
Specimen Num: 12
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: pancreas
Detected: true
Specimen Num: 13
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: kidney
Detected: false
Specimen Num: 14
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: spleen
Detected: true
Specimen Num: 15
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: thymus
Detected: true
Specimen Num: 16
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: lymph nodes
Detected: true
Specimen Num: 17
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: bone marrow
Detected: false
Specimen Num: 18
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: skin
Detected: true
Specimen Num: 19
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: gallbladder
Detected: true
Specimen Num: 20
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: urinary bladder
Detected: true
Specimen Num: 21
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: pituitary gland
Detected: true
Specimen Num: 22
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: adrenal gland
Detected: true
Specimen Num: 23
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: salivary gland
Detected: true
Specimen Num: 24
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 25
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: tongue
Detected: true
Specimen Num: 26
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: stomach
Detected: true
Specimen Num: 27
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: small intestine
Detected: true
Specimen Num: 28
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: large intestine
Detected: true
Specimen Num: 29
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: cecum
Detected: true
Specimen Num: 30
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: testis
Detected: true
Specimen Num: 31
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: epididymis
Detected: true
Specimen Num: 32
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: seminal vesicle
Detected: true
Specimen Num: 33
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Male
Emaps: EMAPS:2979428
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: coagulating gland
Detected: true
Specimen Num: 34
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: prostate gland
Detected: true
Specimen Num: 35
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: ovary
Detected: true
Specimen Num: 36
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: uterus
Detected: false
Specimen Num: 37
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GXD Expression      
Probe: MGI:3625118
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3625119
Age: postnatal
Specimen Label: white fat
Detected: true
Specimen Num: 38
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GXD Expression    
Probe: MGI:7528779
Assay Type: RT-PCR
Annotation Date: 2023-09-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7528789
Age: postnatal adult
Image: 6
Specimen Label: Br
Detected: true
Specimen Num: 2
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GXD Expression    
Probe: MGI:7528779
Assay Type: RT-PCR
Annotation Date: 2023-09-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:7528789
Age: postnatal adult
Image: 6
Specimen Label: AG
Detected: true
Specimen Num: 3
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GXD Expression    
Probe: MGI:7528779
Assay Type: RT-PCR
Annotation Date: 2023-09-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624719
Stage: TS19
Assay Id: MGI:7528789
Age: embryonic day 11.5
Image: 6
Specimen Label: EG
Detected: true
Specimen Num: 4
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GXD Expression    
Probe: MGI:8460328
Assay Type: Western blot
Annotation Date: 2026-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:8460349
Age: postnatal adult
Image: 5
Specimen Label: WT
Detected: true
Specimen Num: 1
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•
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GXD Expression    
Probe: MGI:8460328
Assay Type: Western blot
Annotation Date: 2026-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:8460349
Age: postnatal adult
Image: 5
Specimen Label: WT
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression    
Probe: MGI:8460328
Assay Type: Western blot
Annotation Date: 2026-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:8460349
Age: postnatal adult
Image: 5
Specimen Label: WT
Detected: true
Specimen Num: 3
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