|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 127 for Sdccag8

<< First    < Previous  |  Next >    Last >>
0.04s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Serologically defined colon cancer antigen 8 (SDCCAG8), also known as CCCAP (centrosomal colon cancer autoantigen protein), is a family of proteins found in eukaryotes. Mutations of SDCCAG8 are associated with nephronophthisis []and Bardet-Biedl syndrome [], as well as schizophrenia. SDCCAG8 is associated with the centrosome []and interacts with pericentriolar material 1 (PCM1), a centriolar satellite protein crucial for targeting proteins to the centrosome. It regulates centrosomal accumulation of pericentriolar material and neuronal polarisation and migration in the developing mouse cortex [].SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1), which is linked to an autosomal recessive cystic kidney disease, NPHP-RC (nephronophthisis-related ciliopathies). Depletion of SDCCAG8 causes kidney cysts and a body axis defect in zebrafish [].
Publication
First Author: Otto EA
Year: 2010
Journal: Nat Genet
Title: Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy.
Volume: 42
Issue: 10
Pages: 840-50
Publication
First Author: Insolera R
Year: 2014
Journal: Neuron
Title: SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex.
Volume: 83
Issue: 4
Pages: 805-22
Publication  
First Author: Kenedy AA
Year: 2003
Journal: Gene
Title: Identification and characterization of the novel centrosome-associated protein CCCAP.
Volume: 303
Pages: 35-46
Protein
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
Publication
First Author: Airik R
Year: 2014
Journal: J Am Soc Nephrol
Title: Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling.
Volume: 25
Issue: 11
Pages: 2573-83
Publication
First Author: Billingsley G
Year: 2012
Journal: Ophthalmic Genet
Title: Mutational analysis of SDCCAG8 in Bardet-Biedl syndrome patients with renal involvement and absent polydactyly.
Volume: 33
Issue: 3
Pages: 150-4
Publication
First Author: Airik R
Year: 2016
Journal: PLoS One
Title: SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling.
Volume: 11
Issue: 5
Pages: e0156081
Publication
First Author: Tsutsumi R
Year: 2022
Journal: J Biol Chem
Title: The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis.
Volume: 298
Issue: 3
Pages: 101686
Protein
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
Publication
First Author: Ren ZL
Year: 2022
Journal: Zool Res
Title: Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations.
Volume: 43
Issue: 3
Pages: 442-456
Publication
First Author: Weihbrecht K
Year: 2018
Journal: PLoS One
Title: Genotypic and phenotypic characterization of the Sdccag8Tn(sb-Tyr)2161B.CA1C2Ove mouse model.
Volume: 13
Issue: 2
Pages: e0192755
Publication
First Author: Dharmat R
Year: 2018
Journal: J Cell Biol
Title: SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.
Volume: 217
Issue: 8
Pages: 2851-2865
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5705350
Assay Type: Western blot
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5705655
Age: embryonic day 15.5
Specimen Label: Sdccag8+/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5705350
Assay Type: Western blot
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5705655
Age: embryonic day 15.5
Specimen Label: Sdccag8+/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5705350
Assay Type: Western blot
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5705655
Age: embryonic day 15.5
Specimen Label: Sdccag8-/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5705350
Assay Type: Western blot
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5705655
Age: embryonic day 15.5
Specimen Label: Sdccag8-/-
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270424
Pattern: Punctate
Stage: TS24
Assay Id: MGI:5705486
Age: embryonic day 16.5
Note: Expressed at the centrosome (coexpressed Pcnt) as well as the small puncta in the cytoplasm.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5705519
Age: embryonic day 13.5
Specimen Label: 1C left
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5705519
Age: embryonic day 15.5
Specimen Label: 1C middle
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5705519
Age: embryonic day 17.5
Specimen Label: 1C right
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Punctate
Stage: TS24
Assay Id: MGI:5705486
Age: embryonic day 16.5
Note: Expressed at the centrosome (coexpressed Pcnt) as well as the small puncta in the cytoplasm.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Punctate
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Specimen Label: S9B upper
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271123
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Specimen Label: S9B lower
Detected: false
Specimen Num: 6
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Punctate
Stage: TS24
Assay Id: MGI:5705486
Age: embryonic day 16.5
Note: Expressed at the centrosome (coexpressed Pcnt) as well as the small puncta in the cytoplasm.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5705519
Age: embryonic day 13.5
Note: The level of centrosomal was not significantly different from that in other regions. The level of cytoplasmic as small puncta was higher.
Specimen Label: 1C left
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5705519
Age: embryonic day 15.5
Note: The level of centrosomal was not significantly different from that in other regions. The level of cytoplasmic as small puncta was higher.
Specimen Label: 1C middle
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5705519
Age: embryonic day 17.5
Note: The level of centrosomal was not significantly different from that in other regions. The level of cytoplasmic as small puncta was higher.
Specimen Label: 1C right
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5705519
Age: embryonic day 13.5
Note: The level of centrosomal was not significantly different from that in other regions. The level of cytoplasmic as small puncta was higher.
Specimen Label: S1D upper left
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5705519
Age: embryonic day 15.5
Note: The level of centrosomal was not significantly different from that in other regions. The level of cytoplasmic as small puncta was higher.
Specimen Label: S1D upper middle
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5705519
Age: embryonic day 17.5
Note: The level of centrosomal was not significantly different from that in other regions. The level of cytoplasmic as small puncta was higher.
Specimen Label: S1D upper right
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271223
Pattern: Punctate
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Note: Expressed at the centrosome (coexpressed Pcnt) as well as the small puncta in the cytoplasm.
Specimen Label: S1A upper
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271223
Pattern: Punctate
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Specimen Label: S9B upper
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271223
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Specimen Label: S9B lower
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Punctate
Stage: TS24
Assay Id: MGI:5705486
Age: embryonic day 16.5
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5705519
Age: embryonic day 10.5
Specimen Label: S1C
Detected: true
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5705519
Age: embryonic day 17.5
Specimen Label: 1C right
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Punctate
Stage: TS24
Assay Id: MGI:5705486
Age: embryonic day 16.5
Note: Expressed at the centrosome (coexpressed Pcnt) as well as the small puncta in the cytoplasm.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5705519
Age: embryonic day 13.5
Specimen Label: 1C left
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5705519
Age: embryonic day 15.5
Specimen Label: 1C middle
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5705519
Age: embryonic day 13.5
Specimen Label: S1D lower left
Detected: true
Specimen Num: 6
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5705519
Age: embryonic day 15.5
Specimen Label: S1D lower middle
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Punctate
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Note: Expressed at the centrosome (coexpressed Pcnt) as well as the small puncta in the cytoplasm.
Specimen Label: S1A lower
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Punctate
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Note: Expressed at the centrosome inside the junction.
Specimen Label: S1B
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Punctate
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Specimen Label: S9B upper
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5705347
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754723
Stage: TS23
Assay Id: MGI:5705486
Age: embryonic day 15.5
Specimen Label: S9B lower
Detected: false
Specimen Num: 6
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5705519
Age: embryonic day 17.5
Specimen Label: 1C right
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5705519
Age: embryonic day 17.5
Specimen Label: S1D lower right
Detected: true
Specimen Num: 10
Publication  
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load