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Search results 1 to 95 out of 95 for Sdhaf1

0.027s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
644096 | SDHAF1
Type: gene
Organism: human
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Gene
468843 | SDHAF1
Type: gene
Organism: chimpanzee
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Gene
484567 | SDHAF1
Type: gene
Organism: dog, domestic
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Gene
784051 | SDHAF1
Type: gene
Organism: cattle
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Gene
606612 | sdhaf1
Type: gene
Organism: zebrafish
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Gene
711822 | SDHAF1
Type: gene
Organism: macaque, rhesus
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Gene
101732873 | sdhaf1
Type: gene
Organism: frog, western clawed
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Gene
107049539 | SDHAF1
Type: gene
Organism: chicken
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Gene
499125 | Sdhaf1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1915582 | Sdhaf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0029514 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915582 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032464 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031683 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031835 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031792 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032492 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030777 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012748 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030610 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374175
Note: kidney
Specimen Label: JAX_1374175
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374177
Specimen Label: JAX_1374177
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374168
Specimen Label: JAX_1374168
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374171
Specimen Label: JAX_1374171
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1925228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374172
Specimen Label: JAX_1374172
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374166
Specimen Label: JAX_1374166
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374170
Specimen Label: JAX_1374170
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374176
Specimen Label: JAX_1374176
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470974
Specimen Label: JAX_1470974
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470975
Specimen Label: JAX_1470975
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470976
Specimen Label: JAX_1470976
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470977
Specimen Label: JAX_1470977
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470978
Specimen Label: JAX_1470978
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470979
Specimen Label: JAX_1470979
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470980
Specimen Label: JAX_1470980
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6691813
Age: embryonic day 12.5
Image: JAX_1470981
Specimen Label: JAX_1470981
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374169
Specimen Label: JAX_1374169
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374174
Specimen Label: JAX_1374174
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374173
Specimen Label: JAX_1374173
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374164
Specimen Label: JAX_1374164
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374167
Specimen Label: JAX_1374167
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691813
Age: postnatal adult
Image: JAX_1374178
Specimen Label: JAX_1374178
Detected: true
Specimen Num: 22
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Publication
26388266 | J:251621
 
First Author: Boylston JA
Year: 2015
Journal: J Mol Cell Cardiol
Title: Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury.
Volume: 88
Pages: 73-81
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Publication
34686860 | J:320341
First Author: Fujiwara H
Year: 2021
Journal: Nat Immunol
Title: Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
Volume: 22
Issue: 11
Pages: 1440-1451
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26749241 | -
First Author: Maio N
Year: 2016
Journal: Cell Metab
Title: Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB.
Volume: 23
Issue: 2
Pages: 292-302
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Publication
22995659 | -
 
First Author: Ohlenbusch A
Year: 2012
Journal: Orphanet J Rare Dis
Title: Leukoencephalopathy with accumulated succinate is indicative of SDHAF1 related complex II deficiency.
Volume: 7
Pages: 69
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Protein
Q3U276
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Publication
24954417 | -
First Author: Na U
Year: 2014
Journal: Cell Metab
Title: The LYR factors SDHAF1 and SDHAF3 mediate maturation of the iron-sulfur subunit of succinate dehydrogenase.
Volume: 20
Issue: 2
Pages: 253-66
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Gene
6390 | SDHB
Type: gene
Organism: human
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Gene
6392 | SDHD
Type: gene
Organism: human
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Gene
6389 | SDHA
Type: gene
Organism: human
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DO Term
DOID:0060537 | mitochondrial complex II deficiency
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Publication
19465911 | -
First Author: Ghezzi D
Year: 2009
Journal: Nat Genet
Title: SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy.
Volume: 41
Issue: 6
Pages: 654-6
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Protein Domain
IPR045295 | Complex1_LYR_SDHAF1_LYRM8
Type: Domain
Description: SDHAF1, also called LYRM8, is a LYR complex-II specific assembly factor that plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. It promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants []. SDHAF1 may act together with SDHAF3 []. It is mutated in SDH-defective infantile leukoencephalopathy [, ]. SDHAF1 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N terminus.
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