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Search results 1 to 41 out of 41 for Sept7

0.019s

Type

Details

Score

Protein

E9Q1G8

Organism:	Mus musculus/domesticus
Length:	437
Fragment?:	false

•

Protein

E9Q9F5

Organism:	Mus musculus/domesticus
Length:	437
Fragment?:	false

•

Protein

Q3UNN1

Organism:	Mus musculus/domesticus
Length:	418
Fragment?:	false

•

Protein

Q8C2A3

Organism:	Mus musculus/domesticus
Length:	418
Fragment?:	false

•

Protein

Q8C752

Organism:	Mus musculus/domesticus
Length:	126
Fragment?:	false

•

Protein

Q3UGE0

Organism:	Mus musculus/domesticus
Length:	155
Fragment?:	false

•

Protein

Q5DTS3

Organism:	Mus musculus/domesticus
Length:	391
Fragment?:	true

•

Publication

25122120 | J:223786

First Author:	Menon MB
Year:	2014
Journal:	PLoS Genet
Title:	Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.
Volume:	10
Issue:	8
Pages:	e1004558

•

Publication

17564677 | J:122593

First Author:	Fujishima K
Year:	2007
Journal:	J Neurochem
Title:	Targeted disruption of Sept3, a heteromeric assembly partner of Sept5 and Sept7 in axons, has no effect on developing CNS neurons.
Volume:	102
Issue:	1
Pages:	77-92

•

Protein

O55131

Organism:	Mus musculus/domesticus
Length:	436
Fragment?:	false

•

Allele

Septin7<em1Smoc> | MGI:7292225

Name:	septin 7; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Strain

MGI:6771142 | C57BL/6J-Septin7<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Protein Coding Gene

MGI:1335094 | Septin7

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Publication

24113571 | J:205987

First Author:	Ageta-Ishihara N
Year:	2013
Journal:	Nat Commun
Title:	Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.
Volume:	4

Pages:	2532

•

Publication

37686339 | J:340454

First Author:	Szabó L
Year:	2023
Journal:	Int J Mol Sci
Title:	Reduced Expression of Septin7 Hinders Skeletal Muscle Regeneration.
Volume:	24
Issue:	17

•

Publication

22508986 | J:185814

First Author:	Brand F
Year:	2012
Journal:	Mol Cell Biol
Title:	The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology.
Volume:	32
Issue:	13
Pages:	2467-78

•

Publication

21824004 | J:205180

First Author:	Füchtbauer A
Year:	2011
Journal:	Biol Chem
Title:	Septin9 is involved in septin filament formation and cellular stability.
Volume:	392
Issue:	8-9
Pages:	769-77

•

Publication

34993201 | J:317700

First Author:	Dhanya SK
Year:	2021
Journal:	Front Cell Dev Biol
Title:	Deficits Associated With Loss of STIM1 in Purkinje Neurons Including Motor Coordination Can Be Rescued by Loss of Septin 7.
Volume:	9

Pages:	794807

•

Publication

25690008 | J:231500

First Author:	Menon MB
Year:	2015
Journal:	J Cell Sci
Title:	Sep(t)arate or not – how some cells take septin-independent routes through cytokinesis.
Volume:	128
Issue:	10
Pages:	1877-86

•

Publication

22575789 | J:186260

First Author:	Yoshida A
Year:	2012
Journal:	Hear Res
Title:	Localization of septin proteins in the mouse cochlea.
Volume:	289
Issue:	1-2
Pages:	40-51

•

Publication

18460473 | -

First Author:	Zhu M
Year:	2008
Journal:	J Biol Chem
Title:	Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization.
Volume:	283
Issue:	27
Pages:	18916-25

•

Publication

24496452 | -

First Author:	Dash SN
Year:	2014
Journal:	J Cell Sci
Title:	Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis.
Volume:	127
Issue:	Pt 7
Pages:	1476-86

•

Publication

24346071 | -

First Author:	Roth AD
Year:	2013
Journal:	Biol Res
Title:	Septin 7: actin cross-organization is required for axonal association of Schwann cells.
Volume:	46
Issue:	3
Pages:	243-9

•

Publication

24345743 | -

First Author:	Phan QT
Year:	2013
Journal:	MBio
Title:	Role of endothelial cell septin 7 in the endocytosis of Candida albicans.
Volume:	4
Issue:	6
Pages:	e00542-13

•

Publication

22717660 | -

First Author:	Moon IS
Year:	2013
Journal:	Cytotechnology
Title:	Septin 6 localizes to microtubules in neuronal dendrites.
Volume:	65
Issue:	2
Pages:	179-86

•

Publication

12446710 | -

First Author:	Sheffield PJ
Year:	2003
Journal:	J Biol Chem
Title:	Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments.
Volume:	278
Issue:	5
Pages:	3483-8

•

Publication

21544625 | -

First Author:	Cho SJ
Year:	2011
Journal:	Mol Cells
Title:	Septin 6 regulates the cytoarchitecture of neurons through localization at dendritic branch points and bases of protrusions.
Volume:	32
Issue:	1
Pages:	89-98

•

Publication

16914550 | -

First Author:	Low C
Year:	2006
Journal:	J Biol Chem
Title:	Structural analysis of septin 2, 6, and 7 complexes.
Volume:	281
Issue:	41
Pages:	30697-706

•

Publication

25588830 | J:223228

First Author:	Kuo YC
Year:	2015
Journal:	J Cell Sci
Title:	SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins.
Volume:	128
Issue:	5
Pages:	923-34

•

Protein Domain

IPR030644 | SEPT6

Type:

Family

Description:

Septin 6 (SEPT6) belongs to the septin family and forms a complex with SEPT2 and SEPT7 (SEPT2/6/7) [, ]. It is required for ciliogenesis in Kupffer's vesicle, the pronephros, and the neural tube during early embryonic development in zebrafish []. Rat SEPT6 localises to microtubules in neuronal dendrite branch points and bases of protrusions [, ]. It may play a role in hepatitis C virus RNAreplication []. It forms a filamentous structure with SEPTIN12, SEPTIN2, SEPTIN7 and SEPTIN4 at the sperm annulus, required structural integrity and motility of the sperm tail during postmeiotic differentiation [].Septins were first discovered in budding yeast as a major component of bud neck filaments during cell septation [, ]. Later, its homologues were identified in nearly all eukaryotes, including humans. They are all GTP-binding proteins that are involved in diverse cellular functions, including cell cycle progression, vesicle trafficking, cytokinesis, cell migration, membrane dynamics, and chromosome segregation [, ]. Similar to cytoskeleton components such as actins and tubulins, they can assemble into filaments and bundles. However, unlike actin filaments and microtubules, septin filaments are not polar, similarly to intermediate filaments []. The number of septin genes per organism is variable: S. cerevisiae has seven and humans have 13 (SEPT1-12 and SEPT14; SEPT13 is a pseudogene now called SEPT7P2) []. All septins can form heteromeric complexes, which associate to form higher-order structures, including filaments, rings and cage-like formations [, ].

•

Protein Domain

IPR008115 | Septin7

Type:

Family

Description:

Septin 7 (SEPT7) belongs to the septin family. It forms complexes with SEPT4/SEPT8 or SEPT5/SEPT11, and appears to be a common element in most such septin complexes and it has both unusual genomic and structural features []. There are two paralogous septin 7 genes in zebrafish, sept7a and sept7b, among which Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis in zebrafish []. Rat SEPT7 is associated with the cytoplasmic channels of myelinating cells and is required for actin organisation in Schwann cells []. It interacts with centromere-associated protein E (CENPE) and is required for its kinetochore localisation []. C. albicans hyphae is involved in the endocytosis []. Septins were first discovered in budding yeast as a major component of bud neck filaments during cell septation [, ]. Later, its homologues were identified in nearly all eukaryotes, including humans. They are all GTP-binding proteins that are involved in diverse cellular functions, including cell cycle progression, vesicle trafficking, cytokinesis, cell migration, membrane dynamics, and chromosome segregation [, ]. Similar to cytoskeleton components such as actins and tubulins, they can assemble into filaments and bundles. However, unlike actin filaments and microtubules, septin filaments are not polar, similarly to intermediate filaments []. The number of septin genes per organism is variable: S. cerevisiae has seven and humans have 13 (SEPT1-12 and SEPT14; SEPT13 is a pseudogene now called SEPT7P2) []. All septins can form heteromeric complexes, which associate to form higher-order structures, including filaments, rings and cage-like formations [, ].

•

Publication

27634570 | J:237223

First Author:	Torii H
Year:	2016
Journal:	Dev Biol
Title:	Septin7 regulates inner ear formation at an early developmental stage.
Volume:	419
Issue:	2
Pages:	217-228

•

Publication

773946 | -

First Author:	Byers B
Year:	1976
Journal:	J Cell Biol
Title:	A highly ordered ring of membrane-associated filaments in budding yeast.
Volume:	69
Issue:	3
Pages:	717-21

•

Publication

22314400 | -

First Author:	Mostowy S
Year:	2012
Journal:	Nat Rev Mol Cell Biol
Title:	Septins: the fourth component of the cytoskeleton.
Volume:	13
Issue:	3
Pages:	183-94

•

Publication

21990096 | -

First Author:	Hall PA
Year:	2012
Journal:	J Pathol
Title:	Mammalian septins: dynamic heteromers with roles in cellular morphogenesis and compartmentalization.
Volume:	226
Issue:	2
Pages:	287-99

•

Publication

24469395 | -

First Author:	Zhai G
Year:	2014
Journal:	Mol Cell Biol
Title:	Sept6 is required for ciliogenesis in Kupffer's vesicle, the pronephros, and the neural tube during early embryonic development.
Volume:	34
Issue:	7
Pages:	1310-21

•

Publication

4950437 | -

First Author:	Hartwell LH
Year:	1971
Journal:	Exp Cell Res
Title:	Genetic control of the cell division cycle in yeast. IV. Genes controlling bud emergence and cytokinesis.
Volume:	69
Issue:	2
Pages:	265-76

•

Publication

17229681 | -

First Author:	Kim CS
Year:	2007
Journal:	J Virol
Title:	An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication.
Volume:	81
Issue:	8
Pages:	3852-65

•

Protein

Q9R1T4

Organism:	Mus musculus/domesticus
Length:	434
Fragment?:	false

•

Protein

Q3UUU4

Organism:	Mus musculus/domesticus
Length:	427
Fragment?:	false

•

Publication

- | J:238766

First Author:	Shanghai Model Organisms Center
Year:	2017
Journal:	MGI Direct Data Submission
Title:	Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China

•

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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