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Search results 1 to 100 out of 805 for Serpine1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
100127732 | serpine1
Type: gene
Organism: frog, western clawed
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Gene
281375 | SERPINE1
Type: gene
Organism: cattle
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Gene
key_80487 | SERPINE1
Type: gene
Organism: pig, domestic
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Gene
5054 | SERPINE1
Type: gene
Organism: human
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Gene
24617 | Serpine1
Type: gene
Organism: rat
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Gene
403476 | SERPINE1
Type: gene
Organism: dog, domestic
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Gene
472467 | SERPINE1
Type: gene
Organism: chimpanzee
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Gene
100136840 | serpine1
Type: gene
Organism: zebrafish
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Gene
713883 | SERPINE1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:97608 | Serpine1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33904394 | J:306309
   
First Author: Genestine M
Year: 2021
Journal: Elife
Title: Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons.
Volume: 10
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Gene
26135 | SERBP1
Type: gene
Organism: human
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Gene
359996 | SERBP1P2
Type: gene
Organism: human
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Gene
389866 | SERBP1P1
Type: gene
Organism: human
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Gene
442112 | SERBP1P5
Type: gene
Organism: human
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Gene
553148 | SERBP1P3
Type: gene
Organism: human
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Gene
100131241 | LOC100131241
Type: gene
Organism: human
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Gene
100132591 | SERBP1P4
Type: gene
Organism: human
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Gene
100420450 | SERBP1P6
Type: gene
Organism: human
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Protein
Q7TPE9
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: false
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Publication
22383705 | J:196928
First Author: Heberlein KR
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: A novel mRNA binding protein complex promotes localized plasminogen activator inhibitor-1 accumulation at the myoendothelial junction.
Volume: 32
Issue: 5
Pages: 1271-9
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Publication
31054988 | J:277234
First Author: Coudriet GM
Year: 2019
Journal: Am J Pathol
Title: A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes.
Volume: 189
Issue: 7
Pages: 1413-1422
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Publication
23894536 | J:204704
First Author: Chew TG
Year: 2013
Journal: PLoS One
Title: A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption.
Volume: 8
Issue: 7
Pages: e69764
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Publication
10627465 | J:110259
First Author: Eitzman DT
Year: 2000
Journal: Blood
Title: Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice.
Volume: 95
Issue: 2
Pages: 577-80
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Publication
35008904 | J:322314
 
First Author: Okada K
Year: 2022
Journal: Int J Mol Sci
Title: Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair Induced by Glucocorticoids in Mice.
Volume: 23
Issue: 1
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Publication
11292663 | J:120446
First Author: Lambert V
Year: 2001
Journal: FASEB J
Title: Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization.
Volume: 15
Issue: 6
Pages: 1021-7
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Publication
10368124 | J:103348
First Author: Zhu Y
Year: 1999
Journal: Circulation
Title: Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance.
Volume: 99
Issue: 23
Pages: 3050-5
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Publication
24605827 | J:210729
First Author: Tamura Y
Year: 2014
Journal: Endocrinology
Title: Plasminogen activator inhibitor-1 deficiency ameliorates insulin resistance and hyperlipidemia but not bone loss in obese female mice.
Volume: 155
Issue: 5
Pages: 1708-17
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Publication
20501949 | J:161628
First Author: Bauman KA
Year: 2010
Journal: J Clin Invest
Title: The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice.
Volume: 120
Issue: 6
Pages: 1950-60
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Publication
28893232 | J:274156
First Author: Moritake A
Year: 2017
Journal: BMC Musculoskelet Disord
Title: Plasminogen activator inhibitor-1 deficiency enhances subchondral osteopenia after induction of osteoarthritis in mice.
Volume: 18
Issue: 1
Pages: 392
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Publication
11441025 | J:120509
First Author: McMahon GA
Year: 2001
Journal: J Biol Chem
Title: Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesis.
Volume: 276
Issue: 36
Pages: 33964-8
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Publication
15286708 | J:93782
First Author: Bajou K
Year: 2004
Journal: Oncogene
Title: Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth.
Volume: 23
Issue: 41
Pages: 6986-90
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Publication
22984202 | J:191274
First Author: Fang H
Year: 2012
Journal: J Natl Cancer Inst
Title: Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function.
Volume: 104
Issue: 19
Pages: 1470-84
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Publication
16373605 | J:127967
First Author: Otsuka G
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways.
Volume: 26
Issue: 4
Pages: 737-43
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Publication
23715621 | J:208958
First Author: Tamura Y
Year: 2013
Journal: Diabetes
Title: Plasminogen activator inhibitor-1 is involved in streptozotocin-induced bone loss in female mice.
Volume: 62
Issue: 9
Pages: 3170-9
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Publication
24651693 | J:215068
First Author: Mao L
Year: 2014
Journal: PLoS One
Title: Plasminogen activator inhibitor-1 is involved in impaired bone repair associated with diabetes in female mice.
Volume: 9
Issue: 3
Pages: e92686
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Publication
9386191 | J:44500
First Author: Carmeliet P
Year: 1997
Journal: Circulation
Title: Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice.
Volume: 96
Issue: 9
Pages: 3180-91
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Publication
20133900 | J:170864
First Author: Heberlein KR
Year: 2010
Journal: Circ Res
Title: Plasminogen activator inhibitor-1 regulates myoendothelial junction formation.
Volume: 106
Issue: 6
Pages: 1092-102
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Publication
18800031 | J:145639
First Author: Roelofs JJ
Year: 2009
Journal: Kidney Int
Title: Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
Volume: 75
Issue: 1
Pages: 52-9
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Publication
11696429 | J:72394
First Author: Chan JC
Year: 2001
Journal: Am J Pathol
Title: Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice.
Volume: 159
Issue: 5
Pages: 1681-8
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Publication
17067365 | J:135923
First Author: Scroyen I
Year: 2007
Journal: J Thromb Haemost
Title: No functional role of plasminogen activator inhibitor-1 in murine adipogenesis or adipocyte differentiation.
Volume: 5
Issue: 1
Pages: 139-45
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Publication
24024554 | J:231868
First Author: Tucker TA
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Plasminogen activator inhibitor-1 deficiency augments visceral mesothelial organization, intrapleural coagulation, and lung restriction in mice with carbon black/bleomycin-induced pleural injury.
Volume: 50
Issue: 2
Pages: 316-27
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Publication
11792849 | J:73984
First Author: Yamamoto K
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Plasminogen activator inhibitor-1 is a major stress-regulated gene: implications for stress-induced thrombosis in aged individuals.
Volume: 99
Issue: 2
Pages: 890-5
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Publication
16316341 | J:116902
First Author: Krag S
Year: 2005
Journal: Kidney Int
Title: Plasminogen activator inhibitor-1 gene deficiency attenuates TGF-beta1-induced kidney disease.
Volume: 68
Issue: 6
Pages: 2651-66
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Publication
14982862 | J:88462
First Author: Hattori N
Year: 2004
Journal: Am J Pathol
Title: The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism.
Volume: 164
Issue: 3
Pages: 1091-8
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Publication
20009036 | J:158855
First Author: Xu Z
Year: 2010
Journal: Blood
Title: Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture.
Volume: 115
Issue: 10
Pages: 2038-47
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Publication
25679759 | J:219872
First Author: Dittmann M
Year: 2015
Journal: Cell
Title: A serpin shapes the extracellular environment to prevent influenza A virus maturation.
Volume: 160
Issue: 4
Pages: 631-43
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Publication
15944322 | J:100893
First Author: Sejima T
Year: 2005
Journal: J Immunol
Title: Protection of plasminogen activator inhibitor-1-deficient mice from nasal allergy.
Volume: 174
Issue: 12
Pages: 8135-43
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Publication
18469330 | J:139782
First Author: Bajt ML
Year: 2008
Journal: Toxicol Sci
Title: Plasminogen activator inhibitor-1 limits liver injury and facilitates regeneration after acetaminophen overdose.
Volume: 104
Issue: 2
Pages: 419-27
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Publication
16221737 | J:136744
First Author: Bergheim I
Year: 2006
Journal: J Pharmacol Exp Ther
Title: Critical role of plasminogen activator inhibitor-1 in cholestatic liver injury and fibrosis.
Volume: 316
Issue: 2
Pages: 592-600
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Publication
15730388 | J:96321
First Author: Matsushita M
Year: 2005
Journal: Clin Exp Immunol
Title: Plasminogen activator inhibitor-1 is elevated, but not essential, in the development of bleomycin-induced murine scleroderma.
Volume: 139
Issue: 3
Pages: 429-38
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Publication
28588076 | J:266940
First Author: Flevaris P
Year: 2017
Journal: Circulation
Title: Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-β and Cardiac Fibrosis.
Volume: 136
Issue: 7
Pages: 664-679
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Publication
25552599 | J:253123
First Author: Tamura Y
Year: 2015
Journal: Diabetes
Title: Role of plasminogen activator inhibitor-1 in glucocorticoid-induced diabetes and osteopenia in mice.
Volume: 64
Issue: 6
Pages: 2194-206
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Publication
23724005 | J:200713
First Author: Ghosh AK
Year: 2013
Journal: PLoS One
Title: Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis.
Volume: 8
Issue: 5
Pages: e63825
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Publication
16144810 | J:115737
First Author: Liang X
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Plasminogen activator inhibitor-1 modulates adipocyte differentiation.
Volume: 290
Issue: 1
Pages: E103-E113
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Publication
15780082 | J:110122
First Author: Nicholas SB
Year: 2005
Journal: Kidney Int
Title: Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy.
Volume: 67
Issue: 4
Pages: 1297-307
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Publication
8254029 | J:67715
First Author: Carmeliet P
Year: 1993
Journal: J Clin Invest
Title: Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.
Volume: 92
Issue: 6
Pages: 2756-60
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Publication
16528256 | J:136504
First Author: Ma J
Year: 2006
Journal: Kidney Int
Title: Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury.
Volume: 69
Issue: 6
Pages: 1064-72
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Publication
11473641 | J:103959
First Author: Oda T
Year: 2001
Journal: Kidney Int
Title: PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction.
Volume: 60
Issue: 2
Pages: 587-96
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Publication
28899878 | J:268328
First Author: Zhang W
Year: 2018
Journal: FASEB J
Title: Endothelial cells promote triple-negative breast cancer cell metastasis via PAI-1 and CCL5 signaling.
Volume: 32
Issue: 1
Pages: 276-288
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Publication
16931518 | J:117279
First Author: De Taeye BM
Year: 2006
Journal: J Biol Chem
Title: Bone marrow plasminogen activator inhibitor-1 influences the development of obesity.
Volume: 281
Issue: 43
Pages: 32796-805
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Publication
21622848 | J:176331
First Author: Zmijewski JW
Year: 2011
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inhibition of neutrophil apoptosis by PAI-1.
Volume: 301
Issue: 2
Pages: L247-54
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Publication
23494120 | J:196455
First Author: Kenny S
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The role of plasminogen activator inhibitor-1 in gastric mucosal protection.
Volume: 304
Issue: 9
Pages: G814-22
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Publication
12853975 | J:84633
First Author: Almholt K
Year: 2003
Journal: Oncogene
Title: Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice.
Volume: 22
Issue: 28
Pages: 4389-97
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Publication
9701244 | J:49535
First Author: Bajou K
Year: 1998
Journal: Nat Med
Title: Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.
Volume: 4
Issue: 8
Pages: 923-8
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Publication
22307671 | J:186579
First Author: DiMusto PD
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Increased PAI-1 in females compared with males is protective for abdominal aortic aneurysm formation in a rodent model.
Volume: 302
Issue: 7
Pages: H1378-86
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Publication
25356654 | J:223539
First Author: Yan L
Year: 2014
Journal: PLoS One
Title: Effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma in plasminogen activator inhibitor-1 deficient and wild-type mice.
Volume: 9
Issue: 10
Pages: e110869
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Publication
16160004 | J:126198
First Author: Smith LH
Year: 2006
Journal: Blood
Title: Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis.
Volume: 107
Issue: 1
Pages: 132-4
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Publication
12818888 | J:108631
First Author: Savov JD
Year: 2003
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Fibrinolysis in LPS-induced chronic airway disease.
Volume: 285
Issue: 4
Pages: L940-8
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Publication
29371242 | J:274929
First Author: Praetner M
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia-Reperfusion.
Volume: 38
Issue: 4
Pages: 829-842
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Publication
12875966 | J:109418
First Author: Chuang-Tsai S
Year: 2003
Journal: Am J Pathol
Title: Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1.
Volume: 163
Issue: 2
Pages: 445-52
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Publication
21423135 | J:172001
First Author: Kanuri G
Year: 2011
Journal: Lab Invest
Title: Fructose-induced steatosis in mice: role of plasminogen activator inhibitor-1, microsomal triglyceride transfer protein and NKT cells.
Volume: 91
Issue: 6
Pages: 885-95
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Publication
33432099 | J:321984
First Author: Levine JA
Year: 2021
Journal: Sci Rep
Title: Role of PAI-1 in hepatic steatosis and dyslipidemia.
Volume: 11
Issue: 1
Pages: 430
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Publication
28603485 | J:321307
 
First Author: Neuhaus W
Year: 2017
Journal: Front Mol Neurosci
Title: Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury.
Volume: 10
Pages: 149
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Publication
15869599 | J:133227
First Author: Renckens R
Year: 2005
Journal: J Thromb Haemost
Title: The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury.
Volume: 3
Issue: 5
Pages: 1018-25
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Publication
19098125 | J:146567
First Author: Kuramoto E
Year: 2009
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
Volume: 296
Issue: 3
Pages: L337-46
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Publication
12074598 | J:113534
First Author: Oh CK
Year: 2002
Journal: Biochem Biophys Res Commun
Title: PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model.
Volume: 294
Issue: 5
Pages: 1155-60
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Publication
30387130 | J:330393
First Author: Takafuji Y
Year: 2019
Journal: J Cell Physiol
Title: Plasminogen activator inhibitor-1 deficiency suppresses osteoblastic differentiation of mesenchymal stem cells in mice.
Volume: 234
Issue: 6
Pages: 9687-9697
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Publication
18359942 | J:137080
First Author: Shah C
Year: 2008
Journal: J Biol Chem
Title: Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.
Volume: 283
Issue: 20
Pages: 13538-48
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Publication
17032919 | J:144462
First Author: Renckens R
Year: 2007
Journal: Blood
Title: Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia.
Volume: 109
Issue: 4
Pages: 1593-601
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Publication
11141484 | J:67531
First Author: Ploplis VA
Year: 2001
Journal: Am J Pathol
Title: Remodeling of the vessel wall after copper-induced injury is highly attenuated in mice with a total deficiency of plasminogen activator inhibitor-1.
Volume: 158
Issue: 1
Pages: 107-17
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Publication
19443721 | J:154543
First Author: Basu A
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Plasminogen activator inhibitor-1 (PAI-1) facilitates retinal angiogenesis in a model of oxygen-induced retinopathy.
Volume: 50
Issue: 10
Pages: 4974-81
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Publication
12897066 | J:85989
First Author: Hertig A
Year: 2003
Journal: FASEB J
Title: Type 1 plasminogen activator inhibitor deficiency aggravates the course of experimental glomerulonephritis through overactivation of transforming growth factor beta.
Volume: 17
Issue: 13
Pages: 1904-6
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Publication
16785241 | J:116488
First Author: Balsara RD
Year: 2006
Journal: J Biol Chem
Title: A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells.
Volume: 281
Issue: 32
Pages: 22527-36
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Publication
19060228 | J:146313
First Author: Allen GB
Year: 2009
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury.
Volume: 296
Issue: 3
Pages: L277-85
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Publication
21926267 | J:180018
First Author: Miyamoto S
Year: 2011
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice.
Volume: 301
Issue: 6
Pages: L908-16
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Publication
22262246 | J:188470
First Author: Osterholzer JJ
Year: 2012
Journal: J Pathol
Title: PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.
Volume: 228
Issue: 2
Pages: 170-80
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Publication
20203062 | J:159243
First Author: von Montfort C
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: PAI-1 plays a protective role in CCl4-induced hepatic fibrosis in mice: role of hepatocyte division.
Volume: 298
Issue: 5
Pages: G657-66
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Publication
22570200 | J:194569
First Author: Ebrahimian TG
Year: 2012
Journal: Stem Cells
Title: Plasminogen activator inhibitor-1 controls bone marrow-derived cells therapeutic effect through MMP9 signaling: role in physiological and pathological wound healing.
Volume: 30
Issue: 7
Pages: 1436-46
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Publication
30087332 | J:266084
First Author: Ghini F
Year: 2018
Journal: Nat Commun
Title: Endogenous transcripts control miRNA levels and activity in mammalian cells by target-directed miRNA degradation.
Volume: 9
Issue: 1
Pages: 3119
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Publication
21734232 | J:177097
First Author: Courey AJ
Year: 2011
Journal: Blood
Title: The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.
Volume: 118
Issue: 8
Pages: 2313-21
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Publication
29584619 | J:262872
First Author: Pincha N
Year: 2018
Journal: J Clin Invest
Title: PAI1 mediates fibroblast-mast cell interactions in skin fibrosis.
Volume: 128
Issue: 5
Pages: 1807-1819
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Publication
30855280 | J:294427
First Author: McCann JV
Year: 2019
Journal: J Clin Invest
Title: Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1.
Volume: 129
Issue: 4
Pages: 1654-1670
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Publication
32142912 | J:306694
 
First Author: Okada K
Year: 2020
Journal: Bone
Title: PAI-1 is involved in delayed bone repair induced by glucocorticoids in mice.
Volume: 134
Pages: 115310
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Publication
28821477 | J:251861
First Author: Yahata T
Year: 2017
Journal: Blood
Title: TGF-β-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche.
Volume: 130
Issue: 21
Pages: 2283-2294
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16148154 | J:116702
First Author: Arndt PG
Year: 2005
Journal: J Immunol
Title: Regulation of lipopolysaccharide-induced lung inflammation by plasminogen activator Inhibitor-1 through a JNK-mediated pathway.
Volume: 175
Issue: 6
Pages: 4049-59
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Publication
21501583 | J:177896
First Author: Beier JI
Year: 2011
Journal: Arch Biochem Biophys
Title: Plasminogen activator inhibitor-1 deficient mice are protected from angiotensin II-induced fibrosis.
Volume: 510
Issue: 1
Pages: 19-26
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Publication
27317488 | J:236488
First Author: Gupta KK
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4.
Volume: 477
Issue: 3
Pages: 503-8
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Publication
30532990 | J:274301
First Author: Liu Y
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Inhibition of PAI-1 attenuates perirenal fat inflammation and the associated nephropathy in high-fat diet-induced obese mice.
Volume: 316
Issue: 2
Pages: E260-E267
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Publication
24962629 | J:312154
First Author: Farhat YM
Year: 2015
Journal: J Cell Physiol
Title: TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair.
Volume: 230
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Pages: 318-26
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