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Search results 1 to 100 out of 290 for Setd2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhang Y
Year: 2014
Journal: Cell Rep
Title: H3K36 histone methyltransferase Setd2 is required for murine embryonic stem cell differentiation toward endoderm.
Volume: 8
Issue: 6
Pages: 1989-2002
Publication
First Author: Park IY
Year: 2016
Journal: Cell
Title: Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Volume: 166
Issue: 4
Pages: 950-962
Publication
First Author: Ji Z
Year: 2019
Journal: Nat Commun
Title: The histone methyltransferase Setd2 is indispensable for V(D)J recombination.
Volume: 10
Issue: 1
Pages: 3353
Publication  
First Author: Xie Y
Year: 2023
Journal: JCI Insight
Title: SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis.
Volume: 8
Issue: 4
Publication
First Author: Xu Q
Year: 2019
Journal: Nat Genet
Title: SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development.
Volume: 51
Issue: 5
Pages: 844-856
Publication
First Author: Yuan H
Year: 2017
Journal: J Clin Invest
Title: Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.
Volume: 127
Issue: 9
Pages: 3375-3391
Publication  
First Author: Feng W
Year: 2023
Journal: Cancer Lett
Title: Setd2 deficiency promotes gastric tumorigenesis through inhibiting the SIRT1/FOXO pathway.
Volume: 579
Pages: 216470
Publication
First Author: Ding Z
Year: 2022
Journal: Nat Commun
Title: Setd2 supports GATA3(+)ST2(+) thymic-derived Treg cells and suppresses intestinal inflammation.
Volume: 13
Issue: 1
Pages: 7468
Publication
First Author: Rao H
Year: 2023
Journal: Nat Commun
Title: SETD2 deficiency accelerates sphingomyelin accumulation and promotes the development of renal cancer.
Volume: 14
Issue: 1
Pages: 7572
Publication
First Author: Zhang YL
Year: 2018
Journal: Cell Res
Title: Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation.
Volume: 28
Issue: 4
Pages: 476-490
Publication  
First Author: Liu M
Year: 2021
Journal: Redox Biol
Title: The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis.
Volume: 43
Pages: 102004
Publication
First Author: Chang J
Year: 2022
Journal: Cell Rep
Title: Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity.
Volume: 38
Issue: 11
Pages: 110530
Publication
First Author: Leung W
Year: 2022
Journal: Cancer Discov
Title: SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis.
Volume: 12
Issue: 7
Pages: 1782-1803
Publication
First Author: Dong Y
Year: 2019
Journal: Leukemia
Title: SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints.
Volume: 33
Issue: 11
Pages: 2585-2598
Publication
First Author: Wang L
Year: 2018
Journal: PLoS Biol
Title: H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells.
Volume: 16
Issue: 11
Pages: e2006522
Publication
First Author: Chen BY
Year: 2020
Journal: Blood
Title: SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
Volume: 135
Issue: 25
Pages: 2271-2285
Publication  
First Author: Li Y
Year: 2021
Journal: Biochem Biophys Res Commun
Title: SETD2 is essential for terminal differentiation of erythroblasts during fetal erythropoiesis.
Volume: 552
Pages: 98-105
Publication
First Author: Rao H
Year: 2021
Journal: Cancer Res
Title: Multilevel Regulation of β-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma.
Volume: 81
Issue: 13
Pages: 3554-3567
Publication  
First Author: Chen F
Year: 2021
Journal: Front Cell Dev Biol
Title: Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts.
Volume: 9
Pages: 651655
Publication
First Author: Chu SH
Year: 2020
Journal: iScience
Title: Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development.
Volume: 23
Issue: 3
Pages: 100941
Publication
First Author: Walter DM
Year: 2017
Journal: Cancer Res
Title: Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.
Volume: 77
Issue: 7
Pages: 1719-1729
Publication
First Author: Zuo X
Year: 2018
Journal: J Biol Chem
Title: The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice.
Volume: 293
Issue: 24
Pages: 9188-9197
Publication
First Author: Edmunds JW
Year: 2008
Journal: EMBO J
Title: Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation.
Volume: 27
Issue: 2
Pages: 406-20
Publication
First Author: Hu M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling.
Volume: 107
Issue: 7
Pages: 2956-61
Publication  
First Author: Xu L
Year: 2021
Journal: Sci Adv
Title: Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.
Volume: 7
Issue: 1
Publication
First Author: Mar BG
Year: 2017
Journal: Blood
Title: SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia.
Volume: 130
Issue: 24
Pages: 2631-2641
Publication
First Author: Zhou Y
Year: 2018
Journal: Haematologica
Title: Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation.
Volume: 103
Issue: 7
Pages: 1110-1123
Publication
First Author: Chiang YC
Year: 2018
Journal: Cancer Res
Title: SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.
Volume: 78
Issue: 12
Pages: 3135-3146
Publication
First Author: Chen K
Year: 2017
Journal: Cell
Title: Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.
Volume: 170
Issue: 3
Pages: 492-506.e14
Protein
Organism: Mus musculus/domesticus
Length: 2537  
Fragment?: false
Publication
First Author: Moffitt AB
Year: 2017
Journal: J Exp Med
Title: Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.
Volume: 214
Issue: 5
Pages: 1371-1386
Protein
Organism: Mus musculus/domesticus
Length: 2536  
Fragment?: false
Publication
First Author: Xie X
Year: 2021
Journal: Nat Commun
Title: α-TubK40me3 is required for neuronal polarization and migration by promoting microtubule formation.
Volume: 12
Issue: 1
Pages: 4113
Publication
First Author: Zhou XL
Year: 2021
Journal: Aging (Albany NY)
Title: SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice.
Volume: 13
Issue: 5
Pages: 7538-7548
Publication
First Author: Shirane K
Year: 2020
Journal: Nat Genet
Title: NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing.
Volume: 52
Issue: 10
Pages: 1088-1098
Publication
First Author: Lu P
Year: 2024
Journal: Cell Rep
Title: Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis.
Volume: 43
Issue: 2
Pages: 113703
Publication
First Author: Zhang K
Year: 2013
Journal: Dev Biol
Title: CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development.
Volume: 383
Issue: 1
Pages: 15-27
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Huang H
Year: 2019
Journal: Nature
Title: Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally.
Volume: 567
Issue: 7748
Pages: 414-419
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:6828780
Age: embryonic day 12.0
Image: 2
Specimen Label: E12
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:6828780
Age: embryonic day 14.0
Image: 2
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:6828780
Age: embryonic day 16.0
Image: 2
Specimen Label: E16
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:6828780
Age: embryonic day 18.0
Image: 2
Specimen Label: E18
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:6828780
Age: postnatal day 0
Image: 2
Specimen Label: P0
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:6828780
Age: postnatal day 3
Image: 2
Specimen Label: P3
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6828780
Age: postnatal day 7
Image: 2
Specimen Label: P7
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6828780
Age: postnatal day 14
Image: 2
Specimen Label: P14
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6828780
Age: postnatal day 30
Image: 2
Specimen Label: P30
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6828766
Assay Type: RT-PCR
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6828780
Age: postnatal day 60
Image: 2
Specimen Label: P60
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:6828769
Assay Type: Immunohistochemistry
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6828778
Age: embryonic day 14.0
Image: 2b - E14
Specimen Label: 2b - E14
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6828769
Assay Type: Immunohistochemistry
Annotation Date: 2021-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6828778
Age: embryonic day 16.0
Image: 2b - E16
Specimen Label: 2b - E16
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666522
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:6402912
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6402943
Age: embryonic day 2.0
Image: 5A 4 cell
Note: Expression is nuclear.
Specimen Label: 5A 4 cell
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697422
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276322
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Note: Expression was not detected in the face/soft tissues.
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665922
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706822
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674822
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1670622
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738222
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:6402912
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Not Specified
Stage: TS01
Assay Id: MGI:6402943
Age: embryonic day 0.5
Image: 5A 1 cell
Note: Expression is nuclear.
Specimen Label: 5A 1 cell
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1654222
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4423139
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777922
Stage: TS22
Assay Id: MGI:5422108
Age: embryonic day 14.5
Specimen Label: EG1387; Specimen G0476
Detected: false
Specimen Num: 1