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Search results 1 to 100 out of 430 for Setdb1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Jiang Y
Year: 2017
Journal: Nat Genet
Title: The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Volume: 49
Issue: 8
Pages: 1239-1250
Publication
First Author: Cho S
Year: 2012
Journal: Gene Expr Patterns
Title: Dynamics of Setdb1 expression in early mouse development.
Volume: 12
Issue: 5-6
Pages: 213-8
Publication  
First Author: Hachiya R
Year: 2016
Journal: Sci Rep
Title: The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages.
Volume: 6
Pages: 28845
Publication
First Author: Yahiro K
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Histone methyltransferase Setdb1 is indispensable for Meckel's cartilage development.
Volume: 482
Issue: 4
Pages: 883-888
Publication
First Author: Kato M
Year: 2018
Journal: Nat Commun
Title: A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing.
Volume: 9
Issue: 1
Pages: 1683
Publication
First Author: Zeng TB
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: EHMT2 and SETDB1 protect the maternal pronucleus from 5mC oxidation.
Volume: 116
Issue: 22
Pages: 10834-10841
Publication
First Author: Kim J
Year: 2016
Journal: PLoS Genet
Title: Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse.
Volume: 12
Issue: 4
Pages: e1005970
Publication
First Author: Thompson PJ
Year: 2015
Journal: PLoS Genet
Title: hnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cells.
Volume: 11
Issue: 1
Pages: e1004933
Publication
First Author: Cheng EC
Year: 2021
Journal: Cell Rep
Title: The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis.
Volume: 34
Issue: 1
Pages: 108575
Publication
First Author: Bilodeau S
Year: 2009
Journal: Genes Dev
Title: SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state.
Volume: 23
Issue: 21
Pages: 2484-9
Publication      
First Author: Južnić L
Year: 2020
Journal: Gut
Title: SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation.
Publication
First Author: Jiang Y
Year: 2010
Journal: J Neurosci
Title: Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B.
Volume: 30
Issue: 21
Pages: 7152-67
Publication
First Author: Eymery A
Year: 2016
Journal: Development
Title: The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos.
Volume: 143
Issue: 15
Pages: 2767-79
Publication
First Author: Koide S
Year: 2016
Journal: Blood
Title: Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes.
Volume: 128
Issue: 5
Pages: 638-49
Publication
First Author: Adoue V
Year: 2019
Journal: Immunity
Title: The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses.
Volume: 50
Issue: 3
Pages: 629-644.e8
Publication
First Author: Collins PL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes.
Volume: 112
Issue: 27
Pages: 8367-72
Publication
First Author: Mochizuki K
Year: 2021
Journal: Nat Commun
Title: Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing.
Volume: 12
Issue: 1
Pages: 7020
Publication
First Author: Liu S
Year: 2014
Journal: Genes Dev
Title: Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells.
Volume: 28
Issue: 18
Pages: 2041-55
Publication
First Author: Hirota T
Year: 2018
Journal: Dev Cell
Title: SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.
Volume: 47
Issue: 5
Pages: 645-659.e6
Publication
First Author: Ogawa S
Year: 2020
Journal: Gastroenterology
Title: SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice.
Volume: 159
Issue: 2
Pages: 682-696.e13
Publication
First Author: Liu T
Year: 2017
Journal: Biochim Biophys Acta
Title: Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway.
Volume: 1860
Issue: 10
Pages: 1094-1102
Publication  
First Author: Mochizuki K
Year: 2018
Journal: Development
Title: SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling.
Volume: 145
Issue: 23
Publication
First Author: Li H
Year: 2006
Journal: J Biol Chem
Title: The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.
Volume: 281
Issue: 28
Pages: 19489-500
Publication
First Author: Fukuda K
Year: 2018
Journal: Genome Res
Title: A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.
Volume: 28
Issue: 6
Pages: 846-858
Publication  
First Author: Daxinger L
Year: 2016
Journal: Sci Rep
Title: Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype.
Volume: 6
Pages: 25004
Publication
First Author: Yang L
Year: 2002
Journal: Oncogene
Title: Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.
Volume: 21
Issue: 1
Pages: 148-52
Publication
First Author: Matsui T
Year: 2010
Journal: Nature
Title: Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.
Volume: 464
Issue: 7290
Pages: 927-31
Publication
First Author: Pinheiro I
Year: 2012
Journal: Cell
Title: Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Volume: 150
Issue: 5
Pages: 948-60
Publication
First Author: Yang L
Year: 2003
Journal: Biochem J
Title: An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B.
Volume: 369
Issue: Pt 3
Pages: 651-7
Publication
First Author: Wu K
Year: 2020
Journal: Cell Rep
Title: SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.
Volume: 30
Issue: 1
Pages: 25-36.e6
Publication
First Author: Leung D
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1.
Volume: 111
Issue: 18
Pages: 6690-5
Publication
First Author: Pasquarella A
Year: 2016
Journal: Development
Title: Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells.
Volume: 143
Issue: 10
Pages: 1788-99
Publication
First Author: Liu J
Year: 2021
Journal: Nature
Title: The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity.
Volume: 591
Issue: 7849
Pages: 322-326
Publication
First Author: Lohmann F
Year: 2010
Journal: Stem Cells
Title: KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation.
Volume: 28
Issue: 2
Pages: 201-12
Publication
First Author: Cho S
Year: 2013
Journal: Genes Cells
Title: Regulated nuclear entry of over-expressed Setdb1.
Volume: 18
Issue: 8
Pages: 694-703
Publication
First Author: Wang R
Year: 2020
Journal: Nature
Title: Gut stem cell necroptosis by genome instability triggers bowel inflammation.
Volume: 580
Issue: 7803
Pages: 386-390
Publication  
First Author: Thiha P
Year: 2021
Journal: Arch Oral Biol
Title: Histone methyltransferase SET domain bifurcated 1 negatively regulates parathyroid hormone/parathyroid hormone-related peptide receptor to control chondrocyte proliferation in Meckel's cartilage.
Volume: 131
Pages: 105251
Publication
First Author: Sharif J
Year: 2016
Journal: Cell Stem Cell
Title: Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA.
Volume: 19
Issue: 1
Pages: 81-94
Publication
First Author: Zhang K
Year: 2022
Journal: Nat Commun
Title: The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents.
Volume: 13
Issue: 1
Pages: 1423
Publication
First Author: Mysliwiec MR
Year: 2012
Journal: J Biol Chem
Title: Jarid2 (Jumonji, AT rich interactive domain 2) regulates NOTCH1 expression via histone modification in the developing heart.
Volume: 287
Issue: 2
Pages: 1235-41
Publication
First Author: Wang Z
Year: 2022
Journal: Nat Commun
Title: Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm.
Volume: 13
Issue: 1
Pages: 5447
Publication
First Author: Fisher CL
Year: 2017
Journal: Nucleic Acids Res
Title: An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.
Volume: 45
Issue: 21
Pages: e174
Publication  
First Author: Kano S
Year: 2022
Journal: Biochem Biophys Res Commun
Title: The role of the histone methyltransferase SET domain bifurcated 1 during palatal development.
Volume: 598
Pages: 74-80
Publication
First Author: Ideno H
Year: 2013
Journal: Gene Expr Patterns
Title: Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development.
Volume: 13
Issue: 3-4
Pages: 84-90
Publication
First Author: Sridharan R
Year: 2013
Journal: Nat Cell Biol
Title: Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency.
Volume: 15
Issue: 7
Pages: 872-82
Publication
First Author: Jiang Y
Year: 2011
Journal: Neuropharmacology
Title: Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice.
Volume: 60
Issue: 7-8
Pages: 1088-97
Protein
Organism: Mus musculus/domesticus
Length: 1307  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1307  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1308  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lawson KA
Year: 2013
Journal: FEBS Lett
Title: ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development.
Volume: 587
Issue: 24
Pages: 3961-7
Publication
First Author: Abe H
Year: 2022
Journal: Nat Commun
Title: Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation.
Volume: 13
Issue: 1
Pages: 7212
Publication  
First Author: Keniry A
Year: 2016
Journal: Epigenetics Chromatin
Title: Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing.
Volume: 9
Pages: 16
Publication
First Author: Dodge JE
Year: 2004
Journal: Mol Cell Biol
Title: Histone H3-K9 methyltransferase ESET is essential for early development.
Volume: 24
Issue: 6
Pages: 2478-86
GXD Expression      
Probe: MGI:3653610
Assay Type: Northern blot
Annotation Date: 2006-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3653611
Age: postnatal
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3653610
Assay Type: Northern blot
Annotation Date: 2006-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3653611
Age: postnatal
Specimen Label: db/db
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5468102
Assay Type: Western blot
Annotation Date: 2013-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:5468121
Age: postnatal adult
Image: 1
Specimen Label: GV
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5468102
Assay Type: Western blot
Annotation Date: 2013-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5468121
Age: postnatal adult
Image: 1
Specimen Label: MII
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6194850
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194881
Age: embryonic day 16.5
Image: 4
Specimen Label: a
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6194850
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194881
Age: embryonic day 16.5
Image: 4
Specimen Label: b
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6194850
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194881
Age: embryonic day 16.5
Image: 4
Specimen Label: c
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6194850
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194881
Age: embryonic day 16.5
Image: 4
Specimen Label: d
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7414221
Assay Type: Western blot
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:7414289
Age: embryonic day 17.5
Image: 2
Specimen Label: Input
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945543
Age: embryonic day 11.5
Image: g01074 E11.5
Specimen Label: g01074 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945543
Age: embryonic day 15.5
Image: g01074 E15.5
Specimen Label: g01074 E15.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:6194778
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6194862
Age: embryonic day 14.5
Image: 2C
Note: Very weak expression was detected in proliferating chondrocytes. A relatively low expression was observed in the prehypertrophic and hypertrophic chondrocytes.
Specimen Label: 2C
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6194778
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3262520
Stage: TS20
Assay Id: MGI:6194862
Age: embryonic day 12.5
Image: 1C
Specimen Label: 1C
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945543
Age: embryonic day 15.5
Image: g01074 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01074 E15.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666522
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945543
Age: postnatal day 7
Image: g01074 P7
Specimen Label: g01074 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945543
Age: postnatal day 42
Image: g01074 Adult
Specimen Label: g01074 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4417373
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5421972
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: EN1906; Specimen N847
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945543
Age: embryonic day 11.5
Image: g01074 E11.5
Specimen Label: g01074 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945543
Age: embryonic day 15.5
Image: g01074 E15.5
Specimen Label: g01074 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882558
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945543
Age: postnatal day 7
Image: g01074 P7
Specimen Label: g01074 P7
Detected: true
Specimen Num: 3