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Search results 1 to 100 out of 103 for Setx

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Hits by Category

Hits by Strain

Type Details Score
Gene
23064 | SETX
Type: gene
Organism: human
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Gene
100145435 | setx
Type: gene
Organism: frog, western clawed
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Gene
362096 | Setx
Type: gene
Organism: rat
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Gene
480691 | SETX
Type: gene
Organism: dog, domestic
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Gene
464815 | SETX
Type: gene
Organism: chimpanzee
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Gene
534284 | SETX
Type: gene
Organism: cattle
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Gene
417170 | SETX
Type: gene
Organism: chicken
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Gene
562474 | setx
Type: gene
Organism: zebrafish
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Gene
715065 | SETX
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2443480 | Setx
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29725819 | J:320844
First Author: Bennett CL
Year: 2018
Journal: Acta Neuropathol
Title: Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.
Volume: 136
Issue: 3
Pages: 425-443
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Publication
25822250 | J:231861
First Author: Miller MS
Year: 2015
Journal: Nat Immunol
Title: Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis.
Volume: 16
Issue: 5
Pages: 485-94
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Publication
23593030 | J:223053
First Author: Becherel OJ
Year: 2013
Journal: PLoS Genet
Title: Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing.
Volume: 9
Issue: 4
Pages: e1003435
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Publication
30778901 | J:324063
First Author: Becherel OJ
Year: 2019
Journal: Cerebellum
Title: Disruption of Spermatogenesis and Infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2).
Volume: 18
Issue: 3
Pages: 448-456
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Publication
37801077 | J:342545
First Author: Fujiwara Y
Year: 2023
Journal: Reproduction
Title: New allele of mouse DNA/RNA helicase senataxin causes meiotic arrest and infertility.
Volume: 166
Issue: 6
Pages: 437-450
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Publication
24760770 | J:356443
First Author: Fogel BL
Year: 2014
Journal: Hum Mol Genet
Title: Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.
Volume: 23
Issue: 18
Pages: 4758-69
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Publication
29968717 | J:265884
First Author: Andrews AM
Year: 2018
Journal: Nat Commun
Title: A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links.
Volume: 9
Issue: 1
Pages: 2592
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Publication
35732742 | J:338106
First Author: Campisi L
Year: 2022
Journal: Nature
Title: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4.
Volume: 606
Issue: 7916
Pages: 945-952
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Publication
22767893 | J:185950
First Author: Padmanabhan K
Year: 2012
Journal: Science
Title: Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex.
Volume: 337
Issue: 6094
Pages: 599-602
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Publication
24637776 | J:215106
First Author: Yeo AJ
Year: 2014
Journal: PLoS One
Title: R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias.
Volume: 9
Issue: 3
Pages: e90219
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Publication
30010942 | J:267571
First Author: Kannan A
Year: 2018
Journal: Nucleic Acids Res
Title: Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.
Volume: 46
Issue: 16
Pages: 8326-8346
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Publication
32328643 | J:291317
 
First Author: Subramanian GN
Year: 2020
Journal: J Cell Biol
Title: Oocytes mount a noncanonical DNA damage response involving APC-Cdh1-mediated proteolysis.
Volume: 219
Issue: 4
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Protein Coding Gene
MGP_CAROLIEiJ_G0023364 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025954 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025344 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025375 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024803 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024821 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024281 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6256807
Assay Type: RT-PCR
Annotation Date: 2018-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:6256827
Age: embryonic day 17.5
Image: S3
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6256807
Assay Type: RT-PCR
Annotation Date: 2018-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:6256827
Age: embryonic day 17.5
Image: S3
Specimen Label: CKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2373040
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614685
Age: embryonic day 14.5
Note: Cortical plate expression was greater than in the ventricular zone.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6256814
Assay Type: Immunohistochemistry
Annotation Date: 2018-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6256830
Age: embryonic day 17.5
Image: S3b
Specimen Label: S3b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6256814
Assay Type: Immunohistochemistry
Annotation Date: 2018-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6256830
Age: embryonic day 17.5
Image: S3c
Note: Protein levels are reduced in the mutants.
Specimen Label: S3c
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2373040
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614685
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
36542058 | J:332801
   
First Author: Zhao H
Year: 2022
Journal: Elife
Title: Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination.
Volume: 11
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Publication
29497044 | J:265719
First Author: Goffena J
Year: 2018
Journal: Nat Commun
Title: Elongator and codon bias regulate protein levels in mammalian peripheral neurons.
Volume: 9
Issue: 1
Pages: 889
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Publication
29878059 | J:342546
First Author: Schimenti JC
Year: 2018
Journal: Biol Reprod
Title: Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".
Volume: 99
Issue: 6
Pages: 1119-1128
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Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE199664 | RNA-seq of Setx KI and WT Spinal Cord
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Prnp-SETX*R2136H)1920Als | MGI:6881754
Name: transgene insertion 1920, Albert La Spada
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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HT Experiment
GSE199663 | SMART-seq of PD1+ and PD1- CD8 T cells derived from Setx L389S (Setx KI) mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Tg(Prnp-SETX*R2136H)1920Als/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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HT Experiment
GSE224875 | Effect of Setx depletion on gene expression in the testis during the first-wave of spermatogenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Setx<tm1.1Als> | MGI:6881752
Name: senataxin; targeted mutation 1.1, Albert La Spada
Allele Type: Targeted
Attribute String: Humanized sequence
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Transgene
MGI:6881753 | Tg(Prnp-SETX*R2136H)1920Als
Type: transgene
Organism: mouse, laboratory
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DO Term
DOID:0060196 | amyotrophic lateral sclerosis type 4
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Genotype
Genotype
Symbol: Setx/Setx<+>
Background: involves: 129 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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