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Search results 1 to 100 out of 916 for Sfrp1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Secreted frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts []. They have a role in regulating cell growth and differentiation in specific cell types.SFRP1 is an antagonist of the Wnt-Frizzled pathway and is involved in regulating many processes, such as vascular cell proliferation [], heart morphogenesis [], bone trabecular formation []and lung morphogenesis [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:1349614
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1350581
Age: embryonic day 9.5
Image: Sfrp1 psm
Specimen Label: Sfrp1 psm
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1349614
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2969515
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1350581
Age: embryonic day 9.5
Image: Sfrp1 som
Note: Expression is in the lateral tip.
Specimen Label: Sfrp1 som
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3724445
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826226
Age: embryonic day 14.5
Image: 2 Sfrp1
Specimen Label: 2 Sfrp1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724445
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826226
Age: embryonic day 14.5
Image: 5 Sfrp1
Specimen Label: 5 Sfrp1
Detected: true
Specimen Num: 2
Publication
First Author: Foronjy R
Year: 2010
Journal: Am J Pathol
Title: The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema.
Volume: 177
Issue: 2
Pages: 598-607
Publication
First Author: Bodine PV
Year: 2004
Journal: Mol Endocrinol
Title: The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice.
Volume: 18
Issue: 5
Pages: 1222-37
Publication
First Author: Jaspard B
Year: 2000
Journal: Mech Dev
Title: Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis.
Volume: 90
Issue: 2
Pages: 263-7
GXD Expression  
Probe: MGI:3724445
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826226
Age: embryonic day 14.5
Image: Additional file 4 Sfrp1
Specimen Label: Additional file 4 Sfrp1
Detected: true
Specimen Num: 3
Publication
First Author: Rattner A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.
Volume: 94
Issue: 7
Pages: 2859-63
Publication
First Author: Cisneros E
Year: 2020
Journal: Sci Rep
Title: Sfrp1 deficiency makes retinal photoreceptors prone to degeneration.
Volume: 10
Issue: 1
Pages: 5115
Publication
First Author: Ezan J
Year: 2004
Journal: Cardiovasc Res
Title: FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo.
Volume: 63
Issue: 4
Pages: 731-8
Publication
First Author: Rueda-Carrasco J
Year: 2021
Journal: EMBO Rep
Title: SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation.
Volume: 22
Issue: 11
Pages: e51696
Protein
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
Publication
First Author: Esteve P
Year: 2019
Journal: Cereb Cortex
Title: Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation.
Volume: 29
Issue: 3
Pages: 1059-1074
Publication  
First Author: Gauger KJ
Year: 2012
Journal: BMC Dev Biol
Title: Loss of SFRP1 promotes ductal branching in the murine mammary gland.
Volume: 12
Pages: 25
Publication
First Author: Boudin E
Year: 2013
Journal: Bone
Title: Mutations in sFRP1 or sFRP4 are not a common cause of craniotubular hyperostosis.
Volume: 52
Issue: 1
Pages: 292-5
Publication
First Author: Warr N
Year: 2009
Journal: Dev Biol
Title: Sfrp1 and Sfrp2 are required for normal male sexual development in mice.
Volume: 326
Issue: 2
Pages: 273-84
Publication
First Author: Donega V
Year: 2022
Journal: Nat Commun
Title: Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors.
Volume: 13
Issue: 1
Pages: 1036
Publication
First Author: Joesting MS
Year: 2005
Journal: Cancer Res
Title: Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer.
Volume: 65
Issue: 22
Pages: 10423-30
Publication
First Author: Pasold J
Year: 2013
Journal: Exp Cell Res
Title: Reduced expression of Sfrp1 during chondrogenesis and in articular chondrocytes correlates with osteoarthritis in STR/ort mice.
Volume: 319
Issue: 5
Pages: 649-59
Publication
First Author: Satoh W
Year: 2006
Journal: Development
Title: Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis.
Volume: 133
Issue: 6
Pages: 989-99
Publication
First Author: Gauger KJ
Year: 2013
Journal: PLoS One
Title: Mice deficient in Sfrp1 exhibit increased adiposity, dysregulated glucose metabolism, and enhanced macrophage infiltration.
Volume: 8
Issue: 12
Pages: e78320
Publication
First Author: Kele J
Year: 2012
Journal: Stem Cells
Title: SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells.
Volume: 30
Issue: 5
Pages: 865-75
Publication  
First Author: Miao N
Year: 2018
Journal: Front Mol Neurosci
Title: Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex.
Volume: 11
Pages: 247
Publication
First Author: Bao H
Year: 2020
Journal: BMC Biol
Title: Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2.
Volume: 18
Issue: 1
Pages: 151
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191291
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Sfrp1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191291
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Sfrp1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191291
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Sfrp1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191291
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Sfrp1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191291
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Sfrp1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191291
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Sfrp1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6183157
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191291
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Sfrp1
Detected: true
Specimen Num: 7
Publication
First Author: Sugiyama Y
Year: 2013
Journal: Dev Biol
Title: Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.
Volume: 384
Issue: 2
Pages: 181-93
Publication
First Author: Joesting MS
Year: 2008
Journal: Dev Biol
Title: Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate.
Volume: 317
Issue: 1
Pages: 161-73
Publication
First Author: Shiomi T
Year: 2014
Journal: FASEB J
Title: Maintenance of the bronchial alveolar stem cells in an undifferentiated state by secreted frizzled-related protein 1.
Volume: 28
Issue: 12
Pages: 5242-9
Publication
First Author: Esteve P
Year: 2019
Journal: Nat Neurosci
Title: Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
Volume: 22
Issue: 8
Pages: 1258-1268
Publication
First Author: Renström J
Year: 2009
Journal: Cell Stem Cell
Title: Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells.
Volume: 5
Issue: 2
Pages: 157-67
Publication
First Author: Trevant B
Year: 2008
Journal: J Cell Physiol
Title: Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development.
Volume: 217
Issue: 1
Pages: 113-26
Publication
First Author: Matsuyama M
Year: 2014
Journal: J Biol Chem
Title: Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy.
Volume: 289
Issue: 45
Pages: 31526-33
Publication
First Author: Gaur T
Year: 2009
Journal: J Cell Physiol
Title: Secreted frizzled related protein 1 is a target to improve fracture healing.
Volume: 220
Issue: 1
Pages: 174-81
Publication
First Author: Misra K
Year: 2010
Journal: Dev Biol
Title: A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling.
Volume: 337
Issue: 1
Pages: 74-83
Publication
First Author: Wawrzak D
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Wnt3a binds to several sFRPs in the nanomolar range.
Volume: 357
Issue: 4
Pages: 1119-23
Publication
First Author: Yokota T
Year: 2008
Journal: J Immunol
Title: Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis.
Volume: 181
Issue: 9
Pages: 6061-72
Publication
First Author: Leimeister C
Year: 1998
Journal: Mech Dev
Title: Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family.
Volume: 75
Issue: 1-2
Pages: 29-42
Publication
First Author: Kidoya H
Year: 2015
Journal: Dev Cell
Title: APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.
Volume: 33
Issue: 3
Pages: 247-59
Publication
First Author: Satoh W
Year: 2008
Journal: Genesis
Title: Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse.
Volume: 46
Issue: 2
Pages: 92-103
Publication
First Author: Esteve P
Year: 2011
Journal: Nat Neurosci
Title: SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
Volume: 14
Issue: 5
Pages: 562-9
Publication
First Author: Xavier CP
Year: 2014
Journal: Cell Signal
Title: Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.
Volume: 26
Issue: 1
Pages: 94-101
Publication
First Author: Kim BM
Year: 2005
Journal: Dev Cell
Title: The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling.
Volume: 8
Issue: 4
Pages: 611-22
Publication
First Author: Miquelajauregui A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation.
Volume: 104
Issue: 31
Pages: 12919-24
Publication
First Author: Ichijo R
Year: 2017
Journal: Nat Commun
Title: Tbx3-dependent amplifying stem cell progeny drives interfollicular epidermal expansion during pregnancy and regeneration.
Volume: 8
Issue: 1
Pages: 508
Publication
First Author: Marcos S
Year: 2015
Journal: J Neurosci
Title: Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms.
Volume: 35
Issue: 11
Pages: 4729-40
Publication
First Author: Li J
Year: 2011
Journal: Development
Title: SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.
Volume: 138
Issue: 10
Pages: 1977-89
Publication
First Author: Matsuyama M
Year: 2009
Journal: PLoS Genet
Title: Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium.
Volume: 5
Issue: 3
Pages: e1000427
Publication
First Author: Kemp C
Year: 2005
Journal: Dev Dyn
Title: Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.
Volume: 233
Issue: 3
Pages: 1064-75
Publication
First Author: Esteve P
Year: 2011
Journal: Development
Title: Secreted frizzled-related proteins are required for Wnt/β-catenin signalling activation in the vertebrate optic cup.
Volume: 138
Issue: 19
Pages: 4179-84
Publication
First Author: Huang J
Year: 2009
Journal: Development
Title: FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate.
Volume: 136
Issue: 10
Pages: 1741-50
Publication
First Author: Nik AM
Year: 2013
Journal: Gastroenterology
Title: Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.
Volume: 144
Issue: 5
Pages: 1001-11
Publication  
First Author: Pla P
Year: 2008
Journal: Neural Dev
Title: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors.
Volume: 3
Pages: 14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Cain CJ
Year: 2013
Journal: Exp Hematol
Title: Hematopoietic stem cell fate decisions are regulated by Wnt antagonists: comparisons and current controversies.
Volume: 41
Issue: 1
Pages: 3-16
Publication
First Author: Bodine PV
Year: 2005
Journal: J Cell Biochem
Title: The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis.
Volume: 96
Issue: 6
Pages: 1212-30
Publication
First Author: Bodine PV
Year: 2009
Journal: Bone
Title: A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation.
Volume: 44
Issue: 6
Pages: 1063-8
Publication
First Author: Augustine C
Year: 2001
Journal: Mech Dev
Title: Place- and time-dependent expression of mouse sFRP-1 during development of the cerebral neocortex.
Volume: 109
Issue: 2
Pages: 395-7
Publication
First Author: Jones SE
Year: 2002
Journal: Bioessays
Title: Secreted Frizzled-related proteins: searching for relationships and patterns.
Volume: 24
Issue: 9
Pages: 811-20
Publication
First Author: Barandon L
Year: 2003
Journal: Circulation
Title: Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA.
Volume: 108
Issue: 18
Pages: 2282-9
Publication
First Author: Barandon L
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Secreted frizzled-related protein-1 improves postinfarction scar formation through a modulation of inflammatory response.
Volume: 31
Issue: 11
Pages: e80-7
GXD Expression    
Probe: MGI:3586730
Assay Type: RT-PCR
Annotation Date: 2005-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3586765
Age: embryonic day 3.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3586730
Assay Type: RT-PCR
Annotation Date: 2005-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:3586765
Age: embryonic day 5.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3586730
Assay Type: RT-PCR
Annotation Date: 2005-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160399
Stage: TS09
Assay Id: MGI:3586765
Age: embryonic day 6.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3586730
Assay Type: RT-PCR
Annotation Date: 2005-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:3586765
Age: embryonic day 7.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3586730
Assay Type: RT-PCR
Annotation Date: 2005-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3586765
Age: embryonic day 8.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 5