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Search results 1 to 100 out of 996 for Sfrp2

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Type Details Score
Gene
6423 | SFRP2
Type: gene
Organism: human
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Gene
510821 | SFRP2
Type: gene
Organism: cattle
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Gene
395546 | SFRP2
Type: gene
Organism: chicken
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Gene
566878 | sfrp2
Type: gene
Organism: zebrafish
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Gene
699915 | SFRP2
Type: gene
Organism: macaque, rhesus
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Gene
394659 | sfrp2
Type: gene
Organism: frog, western clawed
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Gene
310552 | Sfrp2
Type: gene
Organism: rat
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Gene
475471 | SFRP2
Type: gene
Organism: dog, domestic
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Gene
742398 | SFRP2
Type: gene
Organism: chimpanzee
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Protein Domain
IPR026558 | SFRP2
Type: Family
Description: Secreted frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts []. They have a role in regulating cell growth and differentiation in specific cell types.SFRP2 appears to have a role in development of the neural system, eyes, muscles and limbs [].
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Protein Coding Gene
MGI:108078 | Sfrp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10656762 | J:60407
First Author: Ladher RK
Year: 2000
Journal: Dev Biol
Title: Cloning and expression of the Wnt antagonists Sfrp-2 and Frzb during chick development.
Volume: 218
Issue: 2
Pages: 183-98
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Publication
9096311 | J:39275
First Author: Rattner A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.
Volume: 94
Issue: 7
Pages: 2859-63
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GXD Expression
GXD Expression
 
Probe: MGI:1349615
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1350586
Age: embryonic day 9.5
Image: Sfrp2 psm
Specimen Label: Sfrp2 psm
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1349615
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2969515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1350586
Age: embryonic day 9.5
Image: Sfrp2 som
Note: Expression levels are similar to that of the presomitic mesoderm.
Specimen Label: Sfrp2 som
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7494310
Assay Type: RNA in situ
Annotation Date: 2023-07-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3821526
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7494343
Age: embryonic day 18.5
Image: 1F Sfrp2
Note: Expression higher in non-ossifying suture mesenchyme.
Specimen Label: 1F Sfrp2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1349615
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3114415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1350586
Age: embryonic day 9.5
Image: Sfrp2 som
Note: Expression levels are higher than in the presomitic mesoderm.
Specimen Label: Sfrp2 som
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7576835
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7576863
Age: embryonic day 10.0
Image: 6D Sfrp2 WT
Specimen Label: 6D Sfrp2 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7576835
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640616
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:7576863
Age: embryonic day 10.0
Image: 6D Sfrp2 delta/deltac
Note: Expression reduced and altered compared to control.
Specimen Label: 6D Sfrp2 delta/deltac
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: There is moderate staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Sfrp2 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: There is weak staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus.
Specimen Label: Sfrp2 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450738
Age: embryonic day 11.5
Image: Sfrp2 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Sfrp2 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450738
Age: embryonic day 11.5
Image: Sfrp2 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Sfrp2 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: There is moderate staining in the ventricular zone of the dorsal POA, PVH nucleus and posterior ID. Staining is either absent or ubiquitous in the ventricular zone of the ventral POA, the VMH and ARH nuclei, the AVH and anterior ID.
Specimen Label: Sfrp2 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: There is strong staining in the ventricular zone of the dorsal POA, the AVH, the DAH, the DMH and VMH nuclei and the PH. Staining is either absent or ubiquitous in the ventricular zone of the ventral POA and the PVH, SCH and ARH nuclei.
Specimen Label: Sfrp2 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450738
Age: embryonic day 11.5
Image: Sfrp2 - E11.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Sfrp2 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450738
Age: embryonic day 11.5
Image: Sfrp2 - E11.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Sfrp2 - E11.5
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450738
Age: embryonic day 12.5
Image: Sfrp2 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Sfrp2 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450738
Age: embryonic day 14.5
Image: Sfrp2 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Sfrp2 - E14.5
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585051
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450738
Age: embryonic day 16.5
Image: Sfrp2 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Sfrp2 - E16.5
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:5811074
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5823713
Age: embryonic day 10.5
Image: S1A - Sfrp2 - E10.5
Note: Staining is observed in multiple domains.
Specimen Label: S1A - Sfrp2 - E10.5
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5811074
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823713
Age: embryonic day 11.5
Image: S1A - Sfrp2 - E11.5
Note: Staining is observed in multiple domains.
Specimen Label: S1A - Sfrp2 - E11.5
Detected: true
Specimen Num: 2
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•
•
•
•
Publication
18446812 | J:186306
First Author: Morello R
Year: 2008
Journal: J Cell Physiol
Title: Brachy-syndactyly caused by loss of Sfrp2 function.
Volume: 217
Issue: 1
Pages: 127-37
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•
•
•
•
Publication
- | J:137889
     
First Author: Nathans J
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of an Sfrp2 mutant allele
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Protein
P97299
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
•
•
•
•
•
Protein
Q3UUM9
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
•
•
•
•
•
Protein
Q3UI35
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
•
•
•
•
•
Publication
18729207 | J:138805
First Author: Ikegawa M
Year: 2008
Journal: Dev Dyn
Title: Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice.
Volume: 237
Issue: 9
Pages: 2506-17
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•
•
•
•
Publication
19100252 | J:147206
First Author: Warr N
Year: 2009
Journal: Dev Biol
Title: Sfrp1 and Sfrp2 are required for normal male sexual development in mice.
Volume: 326
Issue: 2
Pages: 273-84
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•
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•
Publication
16467359 | J:106551
First Author: Satoh W
Year: 2006
Journal: Development
Title: Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis.
Volume: 133
Issue: 6
Pages: 989-99
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•
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•
Publication
25972450 | J:228455
First Author: Martin S
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Tissue-nonspecific alkaline phosphatase as a target of sFRP2 in cardiac fibroblasts.
Volume: 309
Issue: 3
Pages: C139-47
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Publication
19017790 | J:142215
First Author: Alfaro MP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair.
Volume: 105
Issue: 47
Pages: 18366-71
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•
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•
Publication
10654605 | J:53153
First Author: Lee CS
Year: 2000
Journal: Development
Title: SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm.
Volume: 127
Issue: 1
Pages: 109-18
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•
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Publication
22290867 | J:190506
First Author: Kele J
Year: 2012
Journal: Stem Cells
Title: SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells.
Volume: 30
Issue: 5
Pages: 865-75
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•
•
•
•
Publication
26071893 | J:317619
 
First Author: Schmeckpeper J
Year: 2015
Journal: J Mol Cell Cardiol
Title: Inhibition of Wnt6 by Sfrp2 regulates adult cardiac progenitor cell differentiation by differential modulation of Wnt pathways.
Volume: 85
Pages: 215-25
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Publication
21673995 | J:174957
First Author: Siamakpour-Reihani S
Year: 2011
Journal: PLoS One
Title: The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus.
Volume: 6
Issue: 6
Pages: e20412
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Publication
19001373 | J:227384
First Author: Kress E
Year: 2009
Journal: J Biol Chem
Title: The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine.
Volume: 284
Issue: 2
Pages: 1234-41
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Publication
27299503 | J:238295
First Author: Ruf F
Year: 2016
Journal: Stem Cells
Title: Loss of Sfrp2 in the Niche Amplifies Stress-Induced Cellular Responses, and Impairs the In Vivo Regeneration of the Hematopoietic Stem Cell Pool.
Volume: 34
Issue: 9
Pages: 2381-92
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Publication
24140542 | J:204680
First Author: Sugiyama Y
Year: 2013
Journal: Dev Biol
Title: Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.
Volume: 384
Issue: 2
Pages: 181-93
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•
•
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GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191292
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Sfrp2
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191292
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Sfrp2
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191292
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Sfrp2
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191292
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Sfrp2
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191292
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Sfrp2
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191292
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Sfrp2
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6183159
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191292
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Sfrp2
Detected: true
Specimen Num: 7
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•
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•
•
Strain
MGI:6187929 | STOCK Tg(Cryd1/Cryaa-Sfrp2)1Jmca
Attribute String: transgenic, mutant stock
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Allele
Tg(Cryd1/Cryaa-Sfrp2)1Jmca | MGI:6187927
Name: transgene insertion 1, John McAvoy
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
18824165 | J:143322
First Author: Chen Y
Year: 2008
Journal: Dev Biol
Title: Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture.
Volume: 324
Issue: 1
Pages: 161-76
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•
•
•
•
Publication
25447442 | J:218778
First Author: Skah S
Year: 2015
Journal: Exp Cell Res
Title: The secreted Frizzled-Related Protein 2 modulates cell fate and the Wnt pathway in the murine intestinal epithelium.
Volume: 330
Issue: 1
Pages: 56-65
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•
•
•
•
Publication
20723538 | J:165596
First Author: von Marschall Z
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling.
Volume: 400
Issue: 3
Pages: 299-304
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•
•
•
Publication
21078975 | J:245307
First Author: He W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.
Volume: 107
Issue: 49
Pages: 21110-5
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•
•
•
Publication
19458075 | J:164762
First Author: Courtwright A
Year: 2009
Journal: Cancer Res
Title: Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway.
Volume: 69
Issue: 11
Pages: 4621-8
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Publication
17251350 | J:119489
First Author: Mirotsou M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair.
Volume: 104
Issue: 5
Pages: 1643-8
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•
Publication
19850029 | J:157031
First Author: Misra K
Year: 2010
Journal: Dev Biol
Title: A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling.
Volume: 337
Issue: 1
Pages: 74-83
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•
Publication
16700072 | J:119228
First Author: Cox S
Year: 2006
Journal: Mol Reprod Dev
Title: Sexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian duct.
Volume: 73
Issue: 8
Pages: 1008-16
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Publication
30942852 | J:275639
First Author: Zamberlam G
Year: 2019
Journal: Endocrinology
Title: SFRP4 Is a Negative Regulator of Ovarian Follicle Development and Female Fertility.
Volume: 160
Issue: 7
Pages: 1561-1572
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•
Publication
17462603 | J:121773
First Author: Wawrzak D
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Wnt3a binds to several sFRPs in the nanomolar range.
Volume: 357
Issue: 4
Pages: 1119-23
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Publication
24087794 | J:206010
First Author: Berthon A
Year: 2014
Journal: Hum Mol Genet
Title: WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.
Volume: 23
Issue: 4
Pages: 889-905
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•
•
•
Publication
11731265 | J:73304
First Author: Tebar M
Year: 2001
Journal: Mech Dev
Title: Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.
Volume: 109
Issue: 2
Pages: 437-40
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•
•
•
•
Publication
9739103 | J:49904
First Author: Leimeister C
Year: 1998
Journal: Mech Dev
Title: Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family.
Volume: 75
Issue: 1-2
Pages: 29-42
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•
•
•
•
Publication
19079247 | J:146963
First Author: Kobayashi K
Year: 2009
Journal: Nat Cell Biol
Title: Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction.
Volume: 11
Issue: 1
Pages: 46-55
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•
•
•
•
Publication
18257070 | J:135313
First Author: Satoh W
Year: 2008
Journal: Genesis
Title: Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse.
Volume: 46
Issue: 2
Pages: 92-103
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•
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•
Publication
12447396 | J:80709
First Author: Aubert J
Year: 2002
Journal: Nat Biotechnol
Title: Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.
Volume: 20
Issue: 12
Pages: 1240-5
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Publication
25788689 | J:220152
First Author: Marcos S
Year: 2015
Journal: J Neurosci
Title: Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms.
Volume: 35
Issue: 11
Pages: 4729-40
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Publication
16962305 | J:113431
First Author: Tavella S
Year: 2006
Journal: Matrix Biol
Title: Forced chondrocyte expression of sonic hedgehog impairs joint formation affecting proliferation and apoptosis.
Volume: 25
Issue: 7
Pages: 389-97
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Publication
26407529 | J:227069
First Author: Huang J
Year: 2015
Journal: Dev Biol
Title: Negative and positive auto-regulation of BMP expression in early eye development.
Volume: 407
Issue: 2
Pages: 256-64
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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