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Search results 1 to 100 out of 117 for Sgf29

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Type Details Score
Gene
112869 | SGF29
Type: gene
Organism: human
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Gene
479792 | SGF29
Type: gene
Organism: dog, domestic
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Gene
510859 | SGF29
Type: gene
Organism: cattle
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Gene
424726 | SGF29
Type: gene
Organism: chicken
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Gene
449813 | sgf29
Type: gene
Organism: zebrafish
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Gene
709124 | SGF29
Type: gene
Organism: macaque, rhesus
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Gene
100144975 | sgf29
Type: gene
Organism: frog, western clawed
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Gene
293488 | Sgf29
Type: gene
Organism: rat
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Gene
454015 | SGF29
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1922815 | Sgf29
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR037802 | SGF29
Type: Family
Description: SAGA-associated factor 29 (SGF29) is a chromatin reader and a component of the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK [, ]. In the SAGA complex, SGF29 binds histone H3 that has been methylated at Lys-4 (H3K4me), and preferably binds the trimethylated form (H3K4me3) []. SGF29 also acts as a boundary, preventing the spread of heterochromatin into neighbouring genes [].The transcription regulatory histone acetylation complex Spt-Ada-Gcn5 acetyltransferase (SAGA) is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. SAGA preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B []. SAGA is known as PCAF in vertebrates and PCAF acetylates nucleosomal histone H3 []. The SAGA complex consists of at least TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1, and some of these components are present as two copies. The complex is built up from distinct modules, each of which has a separate function and crosslinks with either other proteins or other modules in the complex [].SLIK (SAGA-like) is a multi-subunit histone acetyltransferase complex that preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B. It is an embellishment of the SAGA complex. The yeast SLIK complex consists of at least TRA1, CHD1, SPT7, CC TAF5, ADA3, SPT20, RTG2, TAF12, TAF6, HFI1, UBP8 (a deubiquitinase), GCN5, ADA2, SPT3, SGF29, TAF10 and TAF9 [, ].
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Publication
21685874 | -
First Author: Bian C
Year: 2011
Journal: EMBO J
Title: Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Volume: 30
Issue: 14
Pages: 2829-42
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Protein
A0A0U1RNS1
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Protein
Q9DA08
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
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Publication
24307402 | -
First Author: Kamata K
Year: 2014
Journal: J Biochem
Title: The N-terminus and Tudor domains of Sgf29 are important for its heterochromatin boundary formation function.
Volume: 155
Issue: 3
Pages: 159-71
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Protein
A0A0U1RNH1
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: false
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Protein
A0A0U1RPT9
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
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Publication
10026213 | -
First Author: Grant PA
Year: 1999
Journal: J Biol Chem
Title: Expanded lysine acetylation specificity of Gcn5 in native complexes.
Volume: 274
Issue: 9
Pages: 5895-900
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Publication
15647753 | -
First Author: Pray-Grant MG
Year: 2005
Journal: Nature
Title: Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.
Volume: 433
Issue: 7024
Pages: 434-8
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Publication
12446794 | -
First Author: Pray-Grant MG
Year: 2002
Journal: Mol Cell Biol
Title: The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.
Volume: 22
Issue: 24
Pages: 8774-86
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Publication
25216679 | -
First Author: Han Y
Year: 2014
Journal: EMBO J
Title: Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.
Volume: 33
Issue: 21
Pages: 2534-46
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Publication
9674425 | J:320277
First Author: Ogryzko VV
Year: 1998
Journal: Cell
Title: Histone-like TAFs within the PCAF histone acetylase complex.
Volume: 94
Issue: 1
Pages: 35-44
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Publication
19103755 | J:145720
First Author: Guelman S
Year: 2009
Journal: Mol Cell Biol
Title: The double-histone-acetyltransferase complex ATAC is essential for mammalian development.
Volume: 29
Issue: 5
Pages: 1176-88
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Publication
26421618 | -
First Author: Pieters BJ
Year: 2015
Journal: PLoS One
Title: The Role of Electrostatic Interactions in Binding of Histone H3K4me2/3 to the Sgf29 Tandem Tudor Domain.
Volume: 10
Issue: 9
Pages: e0139205
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Protein Coding Gene
MGP_CAROLIEiJ_G0030456 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032990 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032973 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032905 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032978 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1922815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032661 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032907 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033503 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031724 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032129 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013666 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031570 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4845135
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:4848832
Age: embryonic day 10.5
Note: Staining is present in the posterior limb.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845135
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1738219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848832
Age: embryonic day 11.5
Note: Staining is present in the external genitalia.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4845135
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270515
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4848832
Age: embryonic day 9.5
Note: Staining is present in the distal limb.
Specimen Label: Table S4 - E9.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4845135
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:4848832
Age: embryonic day 10.5
Note: Staining is present in the progress zone.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845135
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848832
Age: embryonic day 11.5
Note: Staining is present in the middle limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 3
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Publication
35210392 | J:326061
First Author: Xiao Y
Year: 2022
Journal: Bone Res
Title: RIOX1-demethylated cGAS regulates ionizing radiation-elicited DNA repair.
Volume: 10
Issue: 1
Pages: 19
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Publication
34795452 | J:345359
First Author: Long L
Year: 2021
Journal: Nature
Title: CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity.
Volume: 600
Issue: 7888
Pages: 308-313
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Publication
19936620 | J:314756
First Author: Nagy Z
Year: 2010
Journal: Cell Mol Life Sci
Title: The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes.
Volume: 67
Issue: 4
Pages: 611-28
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Publication
20562830 | J:162081
First Author: Orpinell M
Year: 2010
Journal: EMBO J
Title: The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.
Volume: 29
Issue: 14
Pages: 2381-94
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Publication
11564863 | J:320036
First Author: Martinez E
Year: 2001
Journal: Mol Cell Biol
Title: Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Volume: 21
Issue: 20
Pages: 6782-95
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Publication
19114550 | J:320037
First Author: Nagy Z
Year: 2009
Journal: Mol Cell Biol
Title: The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.
Volume: 29
Issue: 6
Pages: 1649-60
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Publication
18206972 | J:320111
First Author: Zhao Y
Year: 2008
Journal: Mol Cell
Title: A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
Volume: 29
Issue: 1
Pages: 92-101
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Publication
20508642 | J:162104
First Author: Krebs AR
Year: 2010
Journal: EMBO Rep
Title: ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
Volume: 11
Issue: 7
Pages: 541-7
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Publication
- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26578293 | -
 
First Author: Kamps JJ
Year: 2015
Journal: Nat Commun
Title: Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.
Volume: 6
Pages: 8911
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Protein Domain
IPR010750 | SGF29_tudor-like_dom
Type: Domain
Description: SAGA-associated factor 29 (SGF29) is involved in transcriptional regulation as a chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes [, , , , ]. SGF29 specifically recognises and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for the trimethylated form (H3K4me3). It also may be involved in MYC-mediated oncogenic transformation [].This entry represents a the two tandem tudor-like domains found at the C-terminal of yeast and human SAGA-associated factor 29 proteins and the plant homologues. Each of them has a negatively-charged pocket capable of binding H3A1 and an aromatic cage for the recognition of H3K4me2/3 residues [, ].
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Publication
20850016 | -
First Author: Vermeulen M
Year: 2010
Journal: Cell
Title: Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.
Volume: 142
Issue: 6
Pages: 967-80
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GO Term
GO:0000124 | SAGA complex
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Protein Coding Gene
MGI:1196415 | Tada1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923723 | Supt3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929651 | Supt20
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919445 | Supt7l
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3035274 | Tada2b
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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