| Type |
Details |
Score |
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roncagalli R |
| Year: |
2005 |
| Journal: |
Nat Immunol |
| Title: |
Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. |
| Volume: |
6 |
| Issue: |
10 |
| Pages: |
1002-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma C |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex. |
| Volume: |
287 |
| Issue: |
22 |
| Pages: |
18359-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dong Z |
| Year: |
2009 |
| Journal: |
Nat Immunol |
| Title: |
Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells. |
| Volume: |
10 |
| Issue: |
9 |
| Pages: |
973-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cruz-Munoz ME |
| Year: |
2009 |
| Journal: |
Nat Immunol |
| Title: |
Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
297-305 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang N |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. |
| Volume: |
185 |
| Issue: |
10 |
| Pages: |
5683-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu X |
| Year: |
2009 |
| Journal: |
Diabetologia |
| Title: |
Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice. |
| Volume: |
52 |
| Issue: |
10 |
| Pages: |
2130-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van Driel B |
| Year: |
2012 |
| Journal: |
Gastroenterology |
| Title: |
Signaling lymphocyte activation molecule regulates development of colitis in mice. |
| Volume: |
143 |
| Issue: |
6 |
| Pages: |
1544-1554.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calpe S |
| Year: |
2006 |
| Journal: |
Immunogenetics |
| Title: |
Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters. |
| Volume: |
58 |
| Issue: |
1 |
| Pages: |
15-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dong Z |
| Year: |
2012 |
| Journal: |
Immunity |
| Title: |
The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells. |
| Volume: |
36 |
| Issue: |
6 |
| Pages: |
974-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson AD |
| Year: |
1996 |
| Journal: |
Oncogene |
| Title: |
EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene. |
| Volume: |
13 |
| Issue: |
12 |
| Pages: |
2649-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pérez-Quintero LA |
| Year: |
2014 |
| Journal: |
J Exp Med |
| Title: |
EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization. |
| Volume: |
211 |
| Issue: |
4 |
| Pages: |
727-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Talaei N |
| Year: |
2015 |
| Journal: |
J Immunol |
| Title: |
Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling. |
| Volume: |
195 |
| Issue: |
10 |
| Pages: |
4623-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2017 |
| Journal: |
Nature |
| Title: |
SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. |
| Volume: |
544 |
| Issue: |
7651 |
| Pages: |
493-497 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo H |
| Year: |
2015 |
| Journal: |
Mol Cell Biol |
| Title: |
Immune cell inhibition by SLAMF7 is mediated by a mechanism requiring src kinases, CD45, and SHIP-1 that is defective in multiple myeloma cells. |
| Volume: |
35 |
| Issue: |
1 |
| Pages: |
41-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu N |
| Year: |
2016 |
| Journal: |
Nat Immunol |
| Title: |
A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education. |
| Volume: |
17 |
| Issue: |
4 |
| Pages: |
387-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo H |
| Year: |
2016 |
| Journal: |
J Exp Med |
| Title: |
Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. |
| Volume: |
213 |
| Issue: |
10 |
| Pages: |
2187-207 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2018 |
| Journal: |
Database Release |
| Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aldhamen YA |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. |
| Volume: |
186 |
| Issue: |
2 |
| Pages: |
722-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tangye SG |
| Year: |
2002 |
| Journal: |
Eur J Immunol |
| Title: |
CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2. |
| Volume: |
32 |
| Issue: |
6 |
| Pages: |
1640-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Clarkson NG |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Direct and indirect interactions of the cytoplasmic region of CD244 (2B4) in mice and humans with FYN kinase. |
| Volume: |
282 |
| Issue: |
35 |
| Pages: |
25385-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
132
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
132
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Andre Veillette |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
SH2 domain containing 1B1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CD2-Sh2d1b1)#Vei/? |
| Background: |
B6.Cg-Tg(CD2-Sh2d1b1)#Vei |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
SH2 domain containing 1B1; targeted mutation 1.1, Cox Terhorst |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
SH2 domain containing 1B2; targeted mutation 1.1, Cox Terhorst |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
SH2 domain containing 1B1; targeted mutation 2, Andre Veillette |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sh2d1b1/Sh2d1b2/Sh2d1b1/Sh2d1b2 |
| Background: |
involves: BALB/cJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sh2d1b1/Sh2d1b2/Sh2d1b1/Sh2d1b2 |
| Background: |
involves: BALB/cJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sh2d1b1/Sh2d1b1 Sh2d1b2/Sh2d1b2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sh2d1a/Sh2d1a Sh2d1b1/Sh2d1b2/Sh2d1b1/Sh2d1b2 |
| Background: |
involves: 129S4/SvJae * BALB/cJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sh2d1a/Sh2d1a Sh2d1b1/Sh2d1b2/Sh2d1b1/Sh2d1b2 |
| Background: |
involves: 129S4/SvJae * BALB/cJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|