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Search results 1 to 79 out of 79 for Sh2d2a

0.017s

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
9047 | SH2D2A
Type: gene
Organism: human
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Gene
101731988 | sh2d2a
Type: gene
Organism: frog, western clawed
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Gene
310688 | Sh2d2a
Type: gene
Organism: rat
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Gene
457406 | SH2D2A
Type: gene
Organism: chimpanzee
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Gene
530059 | SH2D2A
Type: gene
Organism: cattle
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Gene
100687395 | SH2D2A
Type: gene
Organism: dog, domestic
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Gene
425978 | SH2D2A
Type: gene
Organism: chicken
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Gene
718686 | SH2D2A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1351596 | Sh2d2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23144743 | J:192357
First Author: Berge T
Year: 2012
Journal: PLoS One
Title: SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice.
Volume: 7
Issue: 10
Pages: e48239
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Publication
31541025 | J:288646
First Author: Wedel J
Year: 2019
Journal: J Immunol
Title: T Cell-Specific Adaptor Protein Regulates Mitochondrial Function and CD4+ T Regulatory Cell Activity In Vivo following Transplantation.
Volume: 203
Issue: 8
Pages: 2328-2338
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Protein Coding Gene
MGP_CAROLIEiJ_G0025142 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027086 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1351596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026533 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027185 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026612 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026585 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026083 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10587356 | J:64938
First Author: Rajagopal K
Year: 1999
Journal: J Exp Med
Title: RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation.
Volume: 190
Issue: 11
Pages: 1657-68
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Publication
15962004 | J:99841
First Author: Matsumoto T
Year: 2005
Journal: EMBO J
Title: VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.
Volume: 24
Issue: 13
Pages: 2342-53
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Publication
12953096 | J:85333
First Author: Drappa J
Year: 2003
Journal: J Exp Med
Title: Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice.
Volume: 198
Issue: 5
Pages: 809-21
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Publication
16446380 | J:118955
First Author: Marti F
Year: 2006
Journal: J Exp Med
Title: Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells.
Volume: 203
Issue: 2
Pages: 281-7
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Publication
11435707 | J:70457
First Author: Weterman MA
Year: 2001
Journal: Cytogenet Cell Genet
Title: Genomic structure, chromosomal localization, and embryonic expression of the mouse homolog of PRCC, a gene associated with papillary renal cell carcinoma.
Volume: 92
Issue: 3-4
Pages: 326-32
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Publication
33046503 | J:304062
First Author: Yi FS
Year: 2020
Journal: J Immunol
Title: TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response.
Volume: 205
Issue: 10
Pages: 2926-2935
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Publication
10553045 | J:58458
First Author: Choi YB
Year: 1999
Journal: J Immunol
Title: Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation.
Volume: 163
Issue: 10
Pages: 5242-9
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Publication
24658686 | J:218866
First Author: Bentley K
Year: 2014
Journal: Nat Cell Biol
Title: The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.
Volume: 16
Issue: 4
Pages: 309-21
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Publication
17641043 | J:149941
First Author: Perchonock CE
Year: 2007
Journal: J Immunol
Title: The related adaptors, adaptor in lymphocytes of unknown function X and Rlk/Itk-binding protein, have nonredundant functions in lymphocytes.
Volume: 179
Issue: 3
Pages: 1768-75
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Publication
26286848 | J:230680
First Author: Massena S
Year: 2015
Journal: Blood
Title: Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.
Volume: 126
Issue: 17
Pages: 2016-26
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Publication
25492967 | J:260191
First Author: Granum S
Year: 2014
Journal: Sci Signal
Title: The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.
Volume: 7
Issue: 355
Pages: ra118
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Publication
27436360 | J:259509
First Author: Gordon EJ
Year: 2016
Journal: Sci Signal
Title: The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation.
Volume: 9
Issue: 437
Pages: ra72
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Publication
22689825 | J:189092
First Author: Sun Z
Year: 2012
Journal: J Exp Med
Title: VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.
Volume: 209
Issue: 7
Pages: 1363-77
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Publication
32312382 | J:290236
   
First Author: Smith RO
Year: 2020
Journal: Elife
Title: Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin.
Volume: 9
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Publication
20305788 | J:158899
First Author: Berge T
Year: 2010
Journal: PLoS One
Title: T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.
Volume: 5
Issue: 3
Pages: e9761
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Publication
10964718 | J:64398
First Author: Maier MM
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes.
Volume: 275
Issue: 2
Pages: 652-60
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Publication
15780994 | J:97046
First Author: Zucchelli S
Year: 2005
Journal: Immunity
Title: Defective central tolerance induction in NOD mice: genomics and genetics.
Volume: 22
Issue: 3
Pages: 385-96
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Publication
14706451 | J:87785
First Author: Karim SA
Year: 2004
Journal: Genomics
Title: A physical map of the genomic region on mouse chromosome 3 containing the hindshaker (hsh) mutation.
Volume: 83
Issue: 2
Pages: 225-30
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
16839418 | -
 
First Author: Granum S
Year: 2006
Journal: BMC Immunol
Title: Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7.
Volume: 7
Pages: 15
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Protein Domain
IPR035884 | SH2D2A_SH2
Type: Domain
Description: This entry includes the single SH2 domain of SH2D2A. SH2D2A interacts with and modulates Lck activity [].In general SH2 domains are involved in signal transduction. They typically bind pTyr-containing ligands via two surface pockets, a pTyr and hydrophobic binding pocket, allowing proteins with SH2 domains to localize to tyrosine phosphorylated sites [, , ].
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Publication
9551546 | -
First Author: Barford D
Year: 1998
Journal: Structure
Title: Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.
Volume: 6
Issue: 3
Pages: 249-54
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Protein
Q9QXK9
Organism: Mus musculus/domesticus
Length: 374  
Fragment?: false
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Protein
Q3TA00
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
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Protein
Q5D0E4
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
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Publication
19273114 | -
 
First Author: Kasembeli MM
Year: 2009
Journal: Front Biosci (Landmark Ed)
Title: SH2 domain binding to phosphopeptide ligands: potential for drug targeting.
Volume: 14
Pages: 1010-22
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Publication
19926274 | -
First Author: Filippakopoulos P
Year: 2009
Journal: Curr Opin Struct Biol
Title: SH2 domains: modulators of nonreceptor tyrosine kinase activity.
Volume: 19
Issue: 6
Pages: 643-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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