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Search results 1 to 97 out of 97 for Sh3bp4

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
23677 | SH3BP4
Type: gene
Organism: human
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Gene
496599 | sh3bp4
Type: gene
Organism: frog, western clawed
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Gene
64634 | Sh3bp4
Type: gene
Organism: rat
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Gene
486172 | SH3BP4
Type: gene
Organism: dog, domestic
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Gene
460040 | SH3BP4
Type: gene
Organism: chimpanzee
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Gene
520462 | SH3BP4
Type: gene
Organism: cattle
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Gene
424027 | SH3BP4
Type: gene
Organism: chicken
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Gene
569399 | sh3bp4
Type: gene
Organism: zebrafish
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Gene
693393 | SH3BP4
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR035455 | SH3BP4
Type: Family
Description: SH3BP4 binds to the inactive Rag GTPase complex through its Src homology 3 (SH3) domain and acts as a negative regulator of amino acid-Rag GTPase-mTORC1 signaling []. It has been shown to act as an endocytic accessory protein that interacts with endocytic proteins including clathrin and dynamin, and regulates the internalization of the transferrin receptor (TfR) [].
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Protein Coding Gene
MGI:2138297 | Sh3bp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22575674 | -
First Author: Kim YM
Year: 2012
Journal: Mol Cell
Title: SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.
Volume: 46
Issue: 6
Pages: 833-46
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Publication
30811977 | J:272121
First Author: Antas P
Year: 2019
Journal: Cell Rep
Title: SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization.
Volume: 26
Issue: 9
Pages: 2266-2273.e4
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Publication
16325581 | -
First Author: Tosoni D
Year: 2005
Journal: Cell
Title: TTP specifically regulates the internalization of the transferrin receptor.
Volume: 123
Issue: 5
Pages: 875-88
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Protein
Q921I6
Organism: Mus musculus/domesticus
Length: 962  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0014403 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016270 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016231 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2138297 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016158 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015424 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027639 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015207 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7518338
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_11
Specimen Label: euxassay_001751_11
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_15
Specimen Label: euxassay_001751_15
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_16
Specimen Label: euxassay_001751_16
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_17
Specimen Label: euxassay_001751_17
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_01
Specimen Label: euxassay_001751_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_02
Specimen Label: euxassay_001751_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_03
Specimen Label: euxassay_001751_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_04
Specimen Label: euxassay_001751_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_05
Specimen Label: euxassay_001751_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_06
Specimen Label: euxassay_001751_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_07
Specimen Label: euxassay_001751_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_08
Specimen Label: euxassay_001751_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_09
Specimen Label: euxassay_001751_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_11
Specimen Label: euxassay_001751_11
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_15
Specimen Label: euxassay_001751_15
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_16
Specimen Label: euxassay_001751_16
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_17
Specimen Label: euxassay_001751_17
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_18
Specimen Label: euxassay_001751_18
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_19
Specimen Label: euxassay_001751_19
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:940483
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828037
Age: embryonic day 14.5
Image: euxassay_001751_20
Specimen Label: euxassay_001751_20
Detected: true
Specimen Num: 16
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Publication
33473114 | J:301232
First Author: Butterfield NC
Year: 2021
Journal: Nat Commun
Title: Accelerating functional gene discovery in osteoarthritis.
Volume: 12
Issue: 1
Pages: 467
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Publication
23604909 | J:198500
First Author: Nakahara M
Year: 2013
Journal: Mamm Genome
Title: Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.
Volume: 24
Issue: 5-6
Pages: 228-39
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR035456 | SH3BP4_SH3
Type: Domain
Description: This entry represents the SH3 domain of SH3BP4 (SH3 domain-binding protein 4). SH3BP4 binds to the inactive Rag GTPase complex through its Src homology 3 (SH3) domain and acts as a negative regulator of amino acid-Rag GTPase-mTORC1 signaling []. It has been shown to act as an endocytic accessory protein that interacts with endocytic proteins including clathrin and dynamin, and regulates the internalization of the transferrin receptor (TfR) [].
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