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Search results 1 to 100 out of 144 for Shank2

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0.205s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication  
First Author: Dobrinskikh E
Year: 2015
Journal: Physiol Rep
Title: Shank2 Regulates Renal Albumin Endocytosis.
Volume: 3
Issue: 9
Publication
First Author: Jung ES
Year: 2014
Journal: J Physiol
Title: Shank2 mutant mice display a hypersecretory response to cholera toxin.
Volume: 592
Issue: 8
Pages: 1809-21
Publication
First Author: Lee YS
Year: 2020
Journal: Mol Brain
Title: Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder.
Volume: 13
Issue: 1
Pages: 54
Publication  
First Author: Wegener S
Year: 2018
Journal: eNeuro
Title: Defective Synapse Maturation and Enhanced Synaptic Plasticity in Shank2 Δex7-/- Mice.
Volume: 5
Issue: 3
Publication  
First Author: Yoon SY
Year: 2017
Journal: Mol Pain
Title: A critical role of spinal Shank2 proteins in NMDA-induced pain hypersensitivity.
Volume: 13
Pages: 1744806916688902
Publication  
First Author: Pappas AL
Year: 2017
Journal: JCI Insight
Title: Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.
Volume: 2
Issue: 20
Publication
First Author: Lim CS
Year: 2017
Journal: Neuropharmacology
Title: Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice.
Volume: 112
Issue: Pt A
Pages: 104-112
Publication
First Author: Ha S
Year: 2016
Journal: J Neurosci
Title: Cerebellar Shank2 Regulates Excitatory Synapse Density, Motor Coordination, and Specific Repetitive and Anxiety-Like Behaviors.
Volume: 36
Issue: 48
Pages: 12129-12143
Publication
First Author: Grabrucker S
Year: 2021
Journal: EMBO J
Title: Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism.
Volume: 40
Issue: 5
Pages: e104267
Publication  
First Author: Lee S
Year: 2018
Journal: Front Mol Neurosci
Title: Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice.
Volume: 11
Pages: 209
Publication  
First Author: Lutz AK
Year: 2021
Journal: Front Mol Neurosci
Title: SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(-/-) Mice.
Volume: 14
Pages: 773571
Publication
First Author: Kim R
Year: 2018
Journal: J Neurosci
Title: Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes.
Volume: 38
Issue: 17
Pages: 4076-4092
Publication  
First Author: Ey E
Year: 2018
Journal: Front Mol Neurosci
Title: Shank2 Mutant Mice Display Hyperactivity Insensitive to Methylphenidate and Reduced Flexibility in Social Motivation, but Normal Social Recognition.
Volume: 11
Pages: 365
Publication    
First Author: Ko HG
Year: 2016
Journal: Mol Pain
Title: Reduced acute nociception and chronic pain in Shank2-/- mice.
Volume: 12
Publication  
First Author: Peter S
Year: 2016
Journal: Nat Commun
Title: Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.
Volume: 7
Pages: 12627
Publication
First Author: Won H
Year: 2012
Journal: Nature
Title: Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function.
Volume: 486
Issue: 7402
Pages: 261-5
Publication  
First Author: Yoo YE
Year: 2021
Journal: Front Mol Neurosci
Title: Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice.
Volume: 14
Pages: 712576
Publication  
First Author: Yoo YE
Year: 2022
Journal: Front Mol Neurosci
Title: Brain region and gene dosage-differential transcriptomic changes in Shank2-mutant mice.
Volume: 15
Pages: 977305
Publication  
First Author: Lee S
Year: 2021
Journal: Front Mol Neurosci
Title: Gene Dosage- and Age-Dependent Differential Transcriptomic Changes in the Prefrontal Cortex of Shank2-Mutant Mice.
Volume: 14
Pages: 683196
Publication  
First Author: Sato M
Year: 2017
Journal: eNeuro
Title: Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality.
Volume: 4
Issue: 3
Publication  
First Author: Zhang L
Year: 2023
Journal: Front Immunol
Title: SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis.
Volume: 14
Pages: 1124356
Publication
First Author: Uemura T
Year: 2004
Journal: Mol Cell Neurosci
Title: Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.
Volume: 26
Issue: 2
Pages: 330-41
Publication
First Author: Han KA
Year: 2020
Journal: Mol Autism
Title: Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.
Volume: 11
Issue: 1
Pages: 87
Publication
First Author: Horner AE
Year: 2021
Journal: Genes Brain Behav
Title: Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2.
Volume: 20
Issue: 1
Pages: e12723
Publication  
First Author: Heise C
Year: 2018
Journal: Front Mol Neurosci
Title: Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.
Volume: 11
Pages: 212
Publication  
First Author: Berkel S
Year: 2018
Journal: Front Mol Neurosci
Title: Sex Hormones Regulate SHANK Expression.
Volume: 11
Pages: 337
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Sato M
Year: 2020
Journal: Cell Rep
Title: Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus.
Volume: 32
Issue: 1
Pages: 107864
Publication  
First Author: Ey E
Year: 2013
Journal: Behav Brain Res
Title: The Autism ProSAP1/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations.
Volume: 256
Pages: 677-89
Publication
First Author: Yun M
Year: 2022
Journal: Mol Autism
Title: Enhanced fear limits behavioral flexibility in Shank2-deficient mice.
Volume: 13
Issue: 1
Pages: 40
Publication
First Author: Kim JH
Year: 2009
Journal: Exp Mol Med
Title: Shank 2 expression coincides with neuronal differentiation in the developing retina.
Volume: 41
Issue: 4
Pages: 236-42
GXD Expression      
Probe: MGI:3641149
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:3641158
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3641149
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3641158
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3641149
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641158
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3641149
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641158
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3641149
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641158
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7439227
Age: postnatal day 7.5
Image: 3
Specimen Label: P7.5 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7439227
Age: postnatal day 7.5
Image: 3
Specimen Label: P7.5 cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7439245
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7439245
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439252
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 male
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439252
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 female
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7439210
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439257
Age: embryonic day 17.5
Image: 4
Specimen Label: E17.5 female
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7439210
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439257
Age: embryonic day 17.5
Image: 4
Specimen Label: E17.5 male
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439252
Age: postnatal day 7.5
Image: S2
Specimen Label: P7.5 male
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7439185
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439252
Age: postnatal day 7.5
Image: S2
Specimen Label: P7.5 female
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7439210
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439260
Age: postnatal day 7.5
Image: 4
Specimen Label: P7.5 female
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7439210
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439260
Age: postnatal day 7.5
Image: 4
Specimen Label: P7.5 male
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7541315
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7541325
Age: postnatal day 16
Image: 2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7541315
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7541325
Age: postnatal day 16
Image: 2
Specimen Label: Srrm3
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7541315
Assay Type: RT-PCR
Annotation Date: 2023-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7543247
Age: embryonic day 19.0
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7541315
Assay Type: RT-PCR
Annotation Date: 2023-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7543247
Age: embryonic day 19.0
Image: S4
Specimen Label: dMut
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3641152
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3641162
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3641152
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3641162
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3641152
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3641162
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 3
Publication
First Author: Schneider K
Year: 2014
Journal: J Cell Biol
Title: ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function.
Volume: 205
Issue: 2
Pages: 197-215
Publication
First Author: Lee E
Year: 2021
Journal: Nat Commun
Title: Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice.
Volume: 12
Issue: 1
Pages: 5116
Publication
First Author: Schmeisser MJ
Year: 2012
Journal: Nature
Title: Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Volume: 486
Issue: 7402
Pages: 256-60
Publication
First Author: Bencsik N
Year: 2019
Journal: Sci Rep
Title: Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Volume: 9
Issue: 1
Pages: 16843
Publication  
First Author: Sauer AK
Year: 2019
Journal: Int J Mol Sci
Title: Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.
Volume: 20
Issue: 9
Publication  
First Author: Heise C
Year: 2016
Journal: Front Cell Neurosci
Title: Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.
Volume: 10
Pages: 106
Publication
First Author: Raab M
Year: 2010
Journal: Neuroscience
Title: Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system.
Volume: 171
Issue: 2
Pages: 421-33
Publication  
First Author: Lee EJ
Year: 2015
Journal: Nat Commun
Title: Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation.
Volume: 6
Pages: 7168
Publication
First Author: Jiang YH
Year: 2013
Journal: Neuron
Title: Modeling autism by SHANK gene mutations in mice.
Volume: 78
Issue: 1
Pages: 8-27
Publication
First Author: Uchino S
Year: 2006
Journal: J Neurochem
Title: Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.
Volume: 97
Issue: 4
Pages: 1203-14
Publication
First Author: Yang J
Year: 2011
Journal: EMBO J
Title: DGKι regulates presynaptic release during mGluR-dependent LTD.
Volume: 30
Issue: 1
Pages: 165-80
Publication
First Author: Kazdoba TM
Year: 2016
Journal: Genes Brain Behav
Title: Behavioral phenotypes of genetic mouse models of autism.
Volume: 15
Issue: 1
Pages: 7-26
Publication
First Author: de la Torre-Ubieta L
Year: 2016
Journal: Nat Med
Title: Advancing the understanding of autism disease mechanisms through genetics.
Volume: 22
Issue: 4
Pages: 345-61
Publication    
First Author: Harrington AJ
Year: 2016
Journal: Elife
Title: MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.
Volume: 5
Publication
First Author: Chung C
Year: 2019
Journal: Biol Psychiatry
Title: Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice.
Volume: 85
Issue: 7
Pages: 534-543