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Search results 1 to 88 out of 88 for Siglece

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Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGI:1932475 | Siglece
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25187624 | J:217935
 
First Author: Chen GY
Year: 2014
Journal: Elife
Title: Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1.
Volume: 3
Pages: e04066
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Publication
37460871 | J:341210
First Author: Mei Y
Year: 2023
Journal: Nat Cancer
Title: Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response.
Volume: 4
Issue: 9
Pages: 1273-1291
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Publication
24227736 | J:204167
First Author: Claude J
Year: 2013
Journal: J Neurosci
Title: Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst.
Volume: 33
Issue: 46
Pages: 18270-6
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_CAROLIEiJ_G0029632 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032135 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032050 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1932475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012860 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030731 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
11171044 | J:67541
First Author: Yu Z
Year: 2001
Journal: Biochem J
Title: mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain-containing protein tyrosine phosphatases SHP-1 and SHP-2.
Volume: 353
Issue: Pt 3
Pages: 483-92
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
32889432 | J:308561
First Author: Wu Y
Year: 2020
Journal: iScience
Title: Selective Response to Bacterial Infection by Regulating Siglec-E Expression.
Volume: 23
Issue: 9
Pages: 101473
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
35921817 | J:330795
First Author: Wang X
Year: 2022
Journal: Cell Metab
Title: CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.
Volume: 34
Issue: 8
Pages: 1088-1103.e6
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Publication
26147683 | J:239648
First Author: Bettigole SE
Year: 2015
Journal: Nat Immunol
Title: The transcription factor XBP1 is selectively required for eosinophil differentiation.
Volume: 16
Issue: 8
Pages: 829-37
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Publication
30130255 | J:271475
First Author: Stanczak MA
Year: 2018
Journal: J Clin Invest
Title: Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.
Volume: 128
Issue: 11
Pages: 4912-4923
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Publication
24895121 | J:216011
First Author: McMillan SJ
Year: 2014
Journal: J Biol Chem
Title: Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung.
Volume: 289
Issue: 29
Pages: 20370-6
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Publication
34074677 | J:357846
First Author: Friedman DJ
Year: 2021
Journal: Cancer Immunol Res
Title: ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses.
Volume: 9
Issue: 8
Pages: 952-966
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
37492129 | J:338552
 
First Author: Schröder LJ
Year: 2023
Journal: Front Cell Neurosci
Title: Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization.
Volume: 17
Pages: 1207540
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Publication
33007530 | J:301199
 
First Author: Andes FT
Year: 2021
Journal: Bone
Title: The human sialic acid-binding immunoglobulin-like lectin Siglec-9 and its murine homolog Siglec-E control osteoclast activity and bone resorption.
Volume: 143
Pages: 115665
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Publication
35858866 | J:342287
First Author: Li L
Year: 2022
Journal: J Neuroinflammation
Title: Ablation of Siglec-E augments brain inflammation and ischemic injury.
Volume: 19
Issue: 1
Pages: 191
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Publication
29503442 | J:286460
First Author: Flores R
Year: 2019
Journal: Cell Mol Immunol
Title: Siglec genes confer resistance to systemic lupus erythematosus in humans and mice.
Volume: 16
Issue: 2
Pages: 154-164
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Publication
23315163 | J:195429
First Author: McMillan SJ
Year: 2013
Journal: Blood
Title: Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b β2-integrin-dependent signaling.
Volume: 121
Issue: 11
Pages: 2084-94
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Publication
25225409 | J:216476
First Author: Läubli H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer.
Volume: 111
Issue: 39
Pages: 14211-6
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Publication
25846707 | J:220809
   
First Author: Schwarz F
Year: 2015
Journal: Elife
Title: Siglec receptors impact mammalian lifespan by modulating oxidative stress.
Volume: 4
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Publication
27920204 | J:239237
First Author: Siddiqui S
Year: 2017
Journal: J Biol Chem
Title: Studies on the Detection, Expression, Glycosylation, Dimerization, and Ligand Binding Properties of Mouse Siglec-E.
Volume: 292
Issue: 3
Pages: 1029-1037
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Publication
30910970 | J:274372
First Author: Uchiyama S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing.
Volume: 116
Issue: 15
Pages: 7465-7470
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Publication
28100677 | J:264224
First Author: Schwarz F
Year: 2017
Journal: EMBO J
Title: Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen.
Volume: 36
Issue: 6
Pages: 751-760
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Publication
15048729 | J:88879
First Author: Zhang JQ
Year: 2004
Journal: Eur J Immunol
Title: The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.
Volume: 34
Issue: 4
Pages: 1175-84
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
15331780 | J:92405
First Author: Angata T
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.
Volume: 101
Issue: 36
Pages: 13251-6
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Publication
15010206 | J:88423
First Author: García-Frigola C
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
Volume: 122
Issue: 2
Pages: 133-50
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Publication
16857734 | J:113032
First Author: Avril T
Year: 2006
Journal: J Leukoc Biol
Title: Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha2,8-sialyltransferase gene expression.
Volume: 80
Issue: 4
Pages: 787-96
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Publication
19933851 | J:157489
First Author: Boyd CR
Year: 2009
Journal: J Immunol
Title: Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.
Volume: 183
Issue: 12
Pages: 7703-9
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Publication
24924635 | J:219440
First Author: Tomioka Y
Year: 2014
Journal: Biochem Biophys Res Commun
Title: A soluble form of Siglec-9 provides an antitumor benefit against mammary tumor cells expressing MUC1 in transgenic mice.
Volume: 450
Issue: 1
Pages: 532-7
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Publication
27619995 | J:341793
First Author: Wu Y
Year: 2016
Journal: J Immunol
Title: Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis.
Volume: 197
Issue: 8
Pages: 3336-3347
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Publication
34155121 | J:342787
 
First Author: Ibarlucea-Benitez I
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Siglecs-7/9 function as inhibitory immune checkpoints in vivo and can be targeted to enhance therapeutic antitumor immunity.
Volume: 118
Issue: 26
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Publication
37467314 | J:343619
First Author: Schmassmann P
Year: 2023
Journal: Sci Transl Med
Title: Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma.
Volume: 15
Issue: 705
Pages: eadf5302
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Publication
38990656 | J:353447
 
First Author: Cuello HA
Year: 2024
Journal: JCI Insight
Title: Human-specific elimination of epithelial Siglec-XII suppresses the risk of inflammation-driven colorectal cancers.
Volume: 9
Issue: 16
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: liver
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: spleen
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: kidney
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3807907
Age: embryonic day 10.0-11.0
Specimen Label: embryo
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: lung
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: thymus
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: testes
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3807904
Assay Type: Northern blot
Annotation Date: 2008-09-26
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3807907
Age: postnatal
Specimen Label: ovary
Detected: true
Specimen Num: 10
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Allele
Siglece<em6Smoc> | MGI:7292317
Name: sialic acid binding Ig-like lectin E; endonuclease-mediated mutation 6, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429544 | C57BL/6JSmoc-Siglece<em6Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Siglece<em4(SIGLECE)Smoc> | MGI:7292316
Name: sialic acid binding Ig-like lectin E; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Protein
Q91Y57
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
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Strain
MGI:6771152 | C57BL/6JSmoc-Siglece<em4(SIGLEC8)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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