Type |
Details |
Score |
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Han X |
Year: |
2021 |
Journal: |
Cell Stem Cell |
Title: |
A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang T |
Year: |
2010 |
Journal: |
Nat Biotechnol |
Title: |
A mouse knockout library for secreted and transmembrane proteins. |
Volume: |
28 |
Issue: |
7 |
Pages: |
749-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Angata T |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters. |
Volume: |
276 |
Issue: |
48 |
Pages: |
45128-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aizawa H |
Year: |
2003 |
Journal: |
Genomics |
Title: |
Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G). |
Volume: |
82 |
Issue: |
5 |
Pages: |
521-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mao H |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen. |
Volume: |
8 |
Issue: |
6 |
Pages: |
e68143 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ignacio A |
Year: |
2022 |
Journal: |
Immunity |
Title: |
Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization. |
Volume: |
55 |
Issue: |
7 |
Pages: |
1250-1267.e12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ryu S |
Year: |
2022 |
Journal: |
J Clin Invest |
Title: |
Siglec-F-expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis. |
Volume: |
132 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Y |
Year: |
2020 |
Journal: |
iScience |
Title: |
Selective Response to Bacterial Infection by Regulating Siglec-E Expression. |
Volume: |
23 |
Issue: |
9 |
Pages: |
101473 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzukawa M |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice. |
Volume: |
190 |
Issue: |
12 |
Pages: |
5939-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patnode ML |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue. |
Volume: |
288 |
Issue: |
37 |
Pages: |
26533-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang M |
Year: |
2007 |
Journal: |
Blood |
Title: |
Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. |
Volume: |
109 |
Issue: |
10 |
Pages: |
4280-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang X |
Year: |
2022 |
Journal: |
Cell Metab |
Title: |
CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. |
Volume: |
34 |
Issue: |
8 |
Pages: |
1088-1103.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
McMillan SJ |
Year: |
2014 |
Journal: |
Immunol Lett |
Title: |
Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model. |
Volume: |
160 |
Issue: |
1 |
Pages: |
11-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lexicon Genetics, Inc |
Year: |
2011 |
Journal: |
Database Download |
Title: |
MGI download of Lexicon knockout data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guo JP |
Year: |
2011 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs. |
Volume: |
44 |
Issue: |
2 |
Pages: |
238-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao Y |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
3822 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossant J |
Year: |
2003 |
Journal: |
MGI Direct Data Submission |
Title: |
A new allele at the Pax6 locus from the Center of Modeling Human Disease |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Morshed N |
Year: |
2020 |
Journal: |
Mol Syst Biol |
Title: |
Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration. |
Volume: |
16 |
Issue: |
12 |
Pages: |
e9819 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tateno H |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity. |
Volume: |
27 |
Issue: |
16 |
Pages: |
5699-710 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gicheva N |
Year: |
2016 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Siglec-F is a novel intestinal M cell marker. |
Volume: |
479 |
Issue: |
1 |
Pages: |
1-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang JQ |
Year: |
2004 |
Journal: |
Eur J Immunol |
Title: |
The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. |
Volume: |
34 |
Issue: |
4 |
Pages: |
1175-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Angata T |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms. |
Volume: |
101 |
Issue: |
36 |
Pages: |
13251-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song DJ |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. |
Volume: |
183 |
Issue: |
8 |
Pages: |
5333-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tateyama H |
Year: |
2019 |
Journal: |
Immunology |
Title: |
Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages. |
Volume: |
158 |
Issue: |
4 |
Pages: |
340-352 |
|
•
•
•
•
•
|
Publication |
First Author: |
Knuplez E |
Year: |
2020 |
Journal: |
J Leukoc Biol |
Title: |
Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls. |
Volume: |
108 |
Issue: |
1 |
Pages: |
43-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei Y |
Year: |
2018 |
Journal: |
Int J Mol Sci |
Title: |
Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice. |
Volume: |
20 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Matsui M |
Year: |
2020 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model. |
Volume: |
526 |
Issue: |
3 |
Pages: |
599-606 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kiwamoto T |
Year: |
2015 |
Journal: |
J Allergy Clin Immunol |
Title: |
Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis. |
Volume: |
135 |
Issue: |
5 |
Pages: |
1329-1340.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
569
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
sialic acid binding Ig-like lectin F; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
sialic acid binding Ig-like lectin F; endonuclease-mediated mutation 3, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
sialic acid binding Ig-like lectin F; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen F |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion. |
Volume: |
38 |
Issue: |
2 |
Pages: |
110215 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen S |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Tsc1 controls the development and function of alveolar macrophages. |
Volume: |
498 |
Issue: |
3 |
Pages: |
592-596 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pfirschke C |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Tumor-Promoting Ly-6G(+) SiglecF(high) Cells Are Mature and Long-Lived Neutrophils. |
Volume: |
32 |
Issue: |
12 |
Pages: |
108164 |
|
•
•
•
•
•
|