Type |
Details |
Score |
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Ding C |
Year: |
2007 |
Journal: |
PLoS One |
Title: |
Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation. |
Volume: |
2 |
Issue: |
10 |
Pages: |
e997 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen W |
Year: |
2013 |
Journal: |
Cell |
Title: |
Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation. |
Volume: |
152 |
Issue: |
3 |
Pages: |
467-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Korn MA |
Year: |
2023 |
Journal: |
Front Immunol |
Title: |
Epistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus. |
Volume: |
14 |
|
Pages: |
1095830 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen GY |
Year: |
2009 |
Journal: |
Science |
Title: |
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. |
Volume: |
323 |
Issue: |
5922 |
Pages: |
1722-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang T |
Year: |
2010 |
Journal: |
Nat Biotechnol |
Title: |
A mouse knockout library for secreted and transmembrane proteins. |
Volume: |
28 |
Issue: |
7 |
Pages: |
749-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jellusova J |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity. |
Volume: |
184 |
Issue: |
7 |
Pages: |
3618-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagamachi A |
Year: |
2013 |
Journal: |
Cancer Cell |
Title: |
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. |
Volume: |
24 |
Issue: |
3 |
Pages: |
305-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aizawa H |
Year: |
2003 |
Journal: |
Genomics |
Title: |
Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G). |
Volume: |
82 |
Issue: |
5 |
Pages: |
521-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoffmann A |
Year: |
2007 |
Journal: |
Nat Immunol |
Title: |
Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population. |
Volume: |
8 |
Issue: |
7 |
Pages: |
695-704 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duong BH |
Year: |
2010 |
Journal: |
J Exp Med |
Title: |
Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo. |
Volume: |
207 |
Issue: |
1 |
Pages: |
173-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pfrengle F |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22. |
Volume: |
191 |
Issue: |
4 |
Pages: |
1724-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hutzler S |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells. |
Volume: |
192 |
Issue: |
11 |
Pages: |
5406-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ding Y |
Year: |
2016 |
Journal: |
Nat Immunol |
Title: |
The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation. |
Volume: |
17 |
Issue: |
10 |
Pages: |
1167-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bökers S |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice. |
Volume: |
192 |
Issue: |
7 |
Pages: |
2994-3002 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gruber S |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells. |
Volume: |
14 |
Issue: |
10 |
Pages: |
2348-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Inaba A |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury. |
Volume: |
205 |
Issue: |
5 |
Pages: |
1376-1384 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brenner S |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing. |
Volume: |
30 |
Issue: |
13 |
Pages: |
2705-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang X |
Year: |
2022 |
Journal: |
Cell Metab |
Title: |
CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. |
Volume: |
34 |
Issue: |
8 |
Pages: |
1088-1103.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toubai T |
Year: |
2014 |
Journal: |
Blood |
Title: |
Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice. |
Volume: |
123 |
Issue: |
22 |
Pages: |
3512-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Özgör L |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
Sialic Acid Ligand Binding of CD22 and Siglec-G Determines Distinct B Cell Functions but Is Dispensable for B Cell Tolerance Induction. |
Volume: |
201 |
Issue: |
7 |
Pages: |
2107-2116 |
|
•
•
•
•
•
|
Publication |
First Author: |
Casey SC |
Year: |
2012 |
Journal: |
Mol Endocrinol |
Title: |
The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. |
Volume: |
26 |
Issue: |
6 |
Pages: |
916-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lexicon Genetics, Inc |
Year: |
2011 |
Journal: |
Database Download |
Title: |
MGI download of Lexicon knockout data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Simonetti G |
Year: |
2014 |
Journal: |
Haematologica |
Title: |
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders. |
Volume: |
99 |
Issue: |
8 |
Pages: |
1356-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jellusova J |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Siglec-G regulates B1 cell survival and selection. |
Volume: |
185 |
Issue: |
6 |
Pages: |
3277-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Choi JH |
Year: |
2018 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for Shenandoah. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Choi JH |
Year: |
2018 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for shenandoah2. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Choi JH |
Year: |
2018 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for Montblanc. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong X |
Year: |
2019 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for Sherando. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong X |
Year: |
2019 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for Chamonix. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Angata T |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms. |
Volume: |
101 |
Issue: |
36 |
Pages: |
13251-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7550456 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-11-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:7550466 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7550456 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-11-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:7550466 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:656987 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4828071 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009151_09 |
|
Specimen Label: |
euxassay_009151_09 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:656987 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4828071 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009151_10 |
|
Specimen Label: |
euxassay_009151_10 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:656987 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4828071 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009151_11 |
|
Specimen Label: |
euxassay_009151_11 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:656987 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4828071 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009151_12 |
|
Specimen Label: |
euxassay_009151_12 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:656987 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4828071 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009151_13 |
|
Specimen Label: |
euxassay_009151_13 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:656987 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4828071 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009151_14 |
|
Specimen Label: |
euxassay_009151_14 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
688
 |
Fragment?: |
false |
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Allele |
Name: |
sialic acid binding Ig-like lectin G; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
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Allele |
Name: |
sialic acid binding Ig-like lectin G; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
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Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
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Allele |
Name: |
sialic acid binding Ig-like lectin G; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
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Publication |
First Author: |
Chen GY |
Year: |
2014 |
Journal: |
Elife |
Title: |
Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. |
Volume: |
3 |
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Pages: |
e04066 |
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Publication |
First Author: |
Kim DW |
Year: |
2022 |
Journal: |
Mol Neurodegener |
Title: |
Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes. |
Volume: |
17 |
Issue: |
1 |
Pages: |
83 |
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