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Search results 1 to 93 out of 93 for Siglech

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
361584 | Siglech
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2443256 | Siglech
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7488356
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7488360
Age: embryonic day 12.5
Image: S1G E12.5 SiglecH
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E12.5 SiglecH
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7488356
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7488360
Age: embryonic day 13.5
Image: S1G E13.5 SiglecH
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E13.5 SiglecH
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7488356
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7488360
Age: embryonic day 14.5
Image: S1G E14.5 SiglecH
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E14.5 SiglecH
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7488356
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7488360
Age: embryonic day 15.5
Image: S1G E15.5 SiglecH
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E15.5 SiglecH
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7488356
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7488360
Age: embryonic day 16.5
Image: S1G E16.5 SiglecH
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E16.5 SiglecH
Detected: true
Specimen Num: 5
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Publication
24683186 | J:209974
First Author: Swiecki M
Year: 2014
Journal: J Immunol
Title: Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells.
Volume: 192
Issue: 9
Pages: 4409-16
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Publication
36928414 | J:337732
First Author: Valente M
Year: 2023
Journal: Nat Immunol
Title: Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells.
Volume: 24
Issue: 4
Pages: 714-728
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Publication
28836308 | J:253079
First Author: Konishi H
Year: 2017
Journal: Glia
Title: Siglec-H is a microglia-specific marker that discriminates microglia from CNS-associated macrophages and CNS-infiltrating monocytes.
Volume: 65
Issue: 12
Pages: 1927-1943
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Publication
38351322 | J:361151
First Author: Minutti CM
Year: 2024
Journal: Nat Immunol
Title: Distinct ontogenetic lineages dictate cDC2 heterogeneity.
Volume: 25
Issue: 3
Pages: 448-461
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Publication
30131424 | J:267220
 
First Author: Tomasello E
Year: 2018
Journal: EMBO J
Title: Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.
Volume: 37
Issue: 19
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_CAROLIEiJ_G0029802 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031344 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031064 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013027 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030905 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
32959911 | J:297442
First Author: Konishi H
Year: 2020
Journal: EMBO J
Title: Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction.
Volume: 39
Issue: 22
Pages: e104464
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Publication
31264967 | J:282050
First Author: Koda Y
Year: 2019
Journal: J Clin Invest
Title: Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35.
Volume: 129
Issue: 8
Pages: 3201-3213
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Publication
23118208 | J:217719
First Author: Orr SL
Year: 2013
Journal: Glycobiology
Title: A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.
Volume: 23
Issue: 3
Pages: 363-80
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Publication
27848952 | J:347216
First Author: Arimura K
Year: 2017
Journal: Mucosal Immunol
Title: Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation.
Volume: 10
Issue: 4
Pages: 957-970
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Publication
27075414 | J:275853
 
First Author: Takagi H
Year: 2016
Journal: Sci Rep
Title: Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation.
Volume: 6
Pages: 24477
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
22084408 | J:178613
First Author: Swiecki M
Year: 2011
Journal: J Exp Med
Title: Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo.
Volume: 208
Issue: 12
Pages: 2367-74
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Publication
24591644 | J:207383
First Author: Ippolito GC
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Dendritic cell fate is determined by BCL11A.
Volume: 111
Issue: 11
Pages: E998-1006
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
35921817 | J:330795
First Author: Wang X
Year: 2022
Journal: Cell Metab
Title: CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.
Volume: 34
Issue: 8
Pages: 1088-1103.e6
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
29477579 | J:347613
First Author: Uto T
Year: 2018
Journal: J Allergy Clin Immunol
Title: Critical role of plasmacytoid dendritic cells in induction of oral tolerance.
Volume: 141
Issue: 6
Pages: 2156-2167.e9
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Publication
36753421 | J:333946
First Author: Hattori Y
Year: 2023
Journal: Cell Rep
Title: CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia.
Volume: 42
Issue: 2
Pages: 112092
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Publication
21130004 | J:166504
First Author: Swiecki M
Year: 2010
Journal: Immunity
Title: Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual.
Volume: 33
Issue: 6
Pages: 955-66
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Publication
22177923 | J:179283
First Author: Takagi H
Year: 2011
Journal: Immunity
Title: Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo.
Volume: 35
Issue: 6
Pages: 958-71
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Publication
24086137 | J:214874
First Author: Puttur F
Year: 2013
Journal: PLoS Pathog
Title: Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance.
Volume: 9
Issue: 9
Pages: e1003648
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Publication
16280085 | J:103338
 
First Author: Stefan M
Year: 2005
Journal: BMC Genomics
Title: Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.
Volume: 6
Pages: 157
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
27377589 | J:236472
First Author: Schmitt H
Year: 2016
Journal: J Exp Med
Title: Siglec-H protects from virus-triggered severe systemic autoimmunity.
Volume: 213
Issue: 8
Pages: 1627-44
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Publication
34157360 | J:310641
     
First Author: Li C
Year: 2021
Journal: Neurosci Res
Title: A mouse model of microglia-specific ablation in the embryonic central nervous system.
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Publication
16397130 | J:132557
First Author: Zhang J
Year: 2006
Journal: Blood
Title: Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors.
Volume: 107
Issue: 9
Pages: 3600-8
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
16293595 | J:129371
First Author: Blasius AL
Year: 2006
Journal: Blood
Title: Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.
Volume: 107
Issue: 6
Pages: 2474-6
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Publication
22732587 | J:189788
First Author: Piva L
Year: 2012
Journal: J Immunol
Title: Cutting edge: Clec9A+ dendritic cells mediate the development of experimental cerebral malaria.
Volume: 189
Issue: 3
Pages: 1128-32
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Publication
23633299 | J:198565
First Author: Kopatz J
Year: 2013
Journal: Glia
Title: Siglec-h on activated microglia for recognition and engulfment of glioma cells.
Volume: 61
Issue: 7
Pages: 1122-33
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Publication
34497606 | J:312879
 
First Author: Szumilas N
Year: 2021
Journal: Front Immunol
Title: Siglec-H-Deficient Mice Show Enhanced Type I IFN Responses, but Do Not Develop Autoimmunity After Influenza or LCMV Infections.
Volume: 12
Pages: 698420
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GXD Expression
GXD Expression
   
Probe: MGI:6199180
Assay Type: RT-PCR
Annotation Date: 2018-09-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:6199186
Age: embryonic day 17.0
Image: S1
Specimen Label: -/-
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6199180
Assay Type: RT-PCR
Annotation Date: 2018-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:6199186
Age: embryonic day 17.0
Image: S1
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6199180
Assay Type: RT-PCR
Annotation Date: 2018-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:6199186
Age: embryonic day 17.0
Image: S1
Specimen Label: +/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6199180
Assay Type: RT-PCR
Annotation Date: 2018-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:6199186
Age: embryonic day 17.0
Image: S1
Specimen Label: +/+
Detected: true
Specimen Num: 4
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
B7ZMQ5
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
B7ZMQ6
Organism: Mus musculus/domesticus
Length: 332  
Fragment?: false
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Protein
Q4QQK7
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Allele
Siglech<em1Smoc> | MGI:7292321
Name: sialic acid binding Ig-like lectin H; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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GXD Expression
GXD Expression
Probe: MGI:7488353
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7488357
Age: embryonic day 13.5
Image: S1G E13.5 P2RY12
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E13.5 P2RY12
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7488353
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7488357
Age: embryonic day 14.5
Image: S1G E14.5 P2RY12
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E14.5 P2RY12
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:7488353
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7488357
Age: embryonic day 15.5
Image: S1G E15.5 P2RY12
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E15.5 P2RY12
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:7488353
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7488357
Age: embryonic day 16.5
Image: S1G E16.5 P2RY12
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E16.5 P2RY12
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:7488353
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7488357
Age: embryonic day 12.5
Image: S1G E12.5 P2RY12
Note: Almost all P2ry12-expressing cells were positive for Siglech expression.
Specimen Label: S1G E12.5 P2RY12
Detected: true
Specimen Num: 7
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Strain
MGI:6476274 | C57BL/6JSmoc-Siglech<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Siglech<tm1.1(icre)Ciphe> | MGI:6357988
Name: sialic acid binding Ig-like lectin H; targeted mutation 1.1, Centre d'ImmunoPhenomique
Allele Type: Targeted
Attribute String: Recombinase
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Publication
29925996 | J:282415
First Author: Rodrigues PF
Year: 2018
Journal: Nat Immunol
Title: Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells.
Volume: 19
Issue: 7
Pages: 711-722
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Siglech/Siglech<+>
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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