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Search results 1 to 100 out of 190 for Sigmar1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Bernard-Marissal N
Year: 2015
Journal: Brain
Title: Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration.
Volume: 138
Issue: Pt 4
Pages: 875-90
Publication
First Author: Yang H
Year: 2019
Journal: Autophagy
Title: SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance.
Volume: 15
Issue: 9
Pages: 1539-1557
Publication
First Author: Zhao J
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: (+)-Pentazocine Reduces NMDA-Induced Murine Retinal Ganglion Cell Death Through a σR1-Dependent Mechanism.
Volume: 57
Issue: 2
Pages: 453-61
Publication
First Author: Pan L
Year: 2017
Journal: PLoS One
Title: Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.
Volume: 12
Issue: 3
Pages: e0174694
Publication
First Author: Shanmugam A
Year: 2015
Journal: J Neurochem
Title: Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1γ, MIP2, MIP3α, and IL12 (p40/p70) by retinal Müller glial cells.
Volume: 132
Issue: 5
Pages: 546-58
Publication
First Author: Ha Y
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).
Volume: 52
Issue: 10
Pages: 7749-60
Publication
First Author: Abdullah CS
Year: 2018
Journal: J Am Heart Assoc
Title: Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics.
Volume: 7
Issue: 20
Pages: e009775
Publication  
First Author: Mavlyutov TA
Year: 2011
Journal: Mol Vis
Title: Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor.
Volume: 17
Pages: 1034-43
Publication
First Author: Jiang G
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells.
Volume: 47
Issue: 12
Pages: 5576-82
Publication  
First Author: Ha Y
Year: 2012
Journal: Mol Vis
Title: Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1.
Volume: 18
Pages: 2860-70
Publication
First Author: Smith SB
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine.
Volume: 49
Issue: 9
Pages: 4154-61
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Seth P
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor.
Volume: 241
Issue: 2
Pages: 535-40
Publication
First Author: Pan YX
Year: 1998
Journal: J Neurochem
Title: Cloning and characterization of a mouse sigma1 receptor.
Volume: 70
Issue: 6
Pages: 2279-85
Publication
First Author: Langa F
Year: 2003
Journal: Eur J Neurosci
Title: Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.
Volume: 18
Issue: 8
Pages: 2188-96
Publication
First Author: Mavlyutov TA
Year: 2010
Journal: Neuroscience
Title: The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study.
Volume: 167
Issue: 2
Pages: 247-55
Publication  
First Author: Mavlyutov TA
Year: 2013
Journal: Neuroscience
Title: Lack of sigma-1 receptor exacerbates ALS progression in mice.
Volume: 240
Pages: 129-34
Publication  
First Author: Tadić V
Year: 2017
Journal: Neuroscience
Title: Sigma 1 receptor activation modifies intracellular calcium exchange in the G93AhSOD1 ALS model.
Volume: 359
Pages: 105-118
Publication
First Author: Prause J
Year: 2013
Journal: Hum Mol Genet
Title: Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis.
Volume: 22
Issue: 8
Pages: 1581-600
Publication
First Author: Fontanilla D
Year: 2009
Journal: Science
Title: The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator.
Volume: 323
Issue: 5916
Pages: 934-7
Publication
First Author: Castany S
Year: 2018
Journal: Sci Rep
Title: Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice.
Volume: 8
Issue: 1
Pages: 3873
Publication  
First Author: Nieto FR
Year: 2014
Journal: Mol Pain
Title: Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice.
Volume: 10
Pages: 11
Publication  
First Author: Sánchez-Fernández C
Year: 2013
Journal: Neuropharmacology
Title: Potentiation of morphine-induced mechanical antinociception by σ₁ receptor inhibition: role of peripheral σ₁ receptors.
Volume: 70
Pages: 348-58
Publication
First Author: Vidal-Torres A
Year: 2013
Journal: Eur J Pharmacol
Title: Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects.
Volume: 711
Issue: 1-3
Pages: 63-72
Publication  
First Author: Bravo-Caparrós I
Year: 2019
Journal: Front Pharmacol
Title: Sigma-1 Receptor Inhibition Reduces Neuropathic Pain Induced by Partial Sciatic Nerve Transection in Mice by Opioid-Dependent and -Independent Mechanisms.
Volume: 10
Pages: 613
Publication
First Author: Snyder MA
Year: 2016
Journal: J Neurochem
Title: Sigma receptor type 1 knockout mice show a mild deficit in plasticity but no significant change in synaptic transmission in the CA1 region of the hippocampus.
Volume: 138
Issue: 5
Pages: 700-9
Publication
First Author: Navarro G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine.
Volume: 107
Issue: 43
Pages: 18676-81
Publication
First Author: Pabba M
Year: 2014
Journal: J Neurosci
Title: NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus.
Volume: 34
Issue: 34
Pages: 11325-38
Publication
First Author: Guzmán A
Year: 2008
Journal: Environ Mol Mutagen
Title: Induction of hypothermic conditions associated with increased micronuclei formation in sigma-1 receptor knockout mice after administration of the antipsychotic compound E-5842.
Volume: 49
Issue: 9
Pages: 727-33
Publication
First Author: Sabino V
Year: 2009
Journal: Behav Brain Res
Title: Sigma-1 receptor knockout mice display a depressive-like phenotype.
Volume: 198
Issue: 2
Pages: 472-6
Publication
First Author: Chevallier N
Year: 2011
Journal: J Psychopharmacol
Title: Behavioural phenotyping of knockout mice for the sigma-1 (σ₁) chaperone protein revealed gender-related anxiety, depressive-like and memory alterations.
Volume: 25
Issue: 7
Pages: 960-75
Publication
First Author: Tsai SY
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.
Volume: 112
Issue: 47
Pages: E6562-70
Publication
First Author: Pal A
Year: 2012
Journal: Eur J Pharmacol
Title: The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements.
Volume: 682
Issue: 1-3
Pages: 12-20
Publication
First Author: Liu X
Year: 2017
Journal: Oncotarget
Title: Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel.
Volume: 8
Issue: 35
Pages: 59345-59358
Publication
First Author: Francardo V
Year: 2019
Journal: Neurotherapeutics
Title: Pridopidine Induces Functional Neurorestoration Via the Sigma-1 Receptor in a Mouse Model of Parkinson's Disease.
Volume: 16
Issue: 2
Pages: 465-479
Publication  
First Author: Xu Q
Year: 2017
Journal: J Neurol Sci
Title: Sigma-1 receptor in brain ischemia/reperfusion: Possible role in the NR2A-induced pathway to regulate brain-derived neurotrophic factor.
Volume: 376
Pages: 166-175
Publication
First Author: Villard V
Year: 2011
Journal: J Pharmacol Sci
Title: Pharmacological interaction with the sigma1 (σ1)-receptor in the acute behavioral effects of antidepressants.
Volume: 115
Issue: 3
Pages: 279-92
Publication  
First Author: Liu DY
Year: 2018
Journal: Exp Neurol
Title: Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Volume: 308
Pages: 90-99
Publication
First Author: Sambo DO
Year: 2017
Journal: Nat Commun
Title: The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission.
Volume: 8
Issue: 1
Pages: 2228
Publication  
First Author: Eddings CR
Year: 2019
Journal: Neurobiol Dis
Title: Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor.
Volume: 129
Pages: 118-129
Publication  
First Author: Mavlyutov TA
Year: 2016
Journal: Neuroscience
Title: Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody.
Volume: 331
Pages: 148-57
Publication  
First Author: Zhang B
Year: 2017
Journal: Neuropharmacology
Title: Sigma-1 receptor deficiency reduces GABAergic inhibition in the basolateral amygdala leading to LTD impairment and depressive-like behaviors.
Volume: 116
Pages: 387-398
Publication  
First Author: Di T
Year: 2017
Journal: Front Mol Neurosci
Title: Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis Due to Dysfunction of the Hypothalamic Glucocorticoid Receptor in Sigma-1 Receptor Knockout Mice.
Volume: 10
Pages: 287
Publication
First Author: Hayashi T
Year: 2007
Journal: Cell
Title: Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival.
Volume: 131
Issue: 3
Pages: 596-610
Publication
First Author: Mei J
Year: 2001
Journal: Biochem Pharmacol
Title: Molecular cloning and pharmacological characterization of the rat sigma1 receptor.
Volume: 62
Issue: 3
Pages: 349-55
Publication
First Author: Shioda N
Year: 2012
Journal: J Biol Chem
Title: Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis.
Volume: 287
Issue: 28
Pages: 23318-31
Publication
First Author: Tagashira H
Year: 2013
Journal: Biochim Biophys Acta
Title: Stimulation of σ1-receptor restores abnormal mitochondrial Ca²⁺ mobilization and ATP production following cardiac hypertrophy.
Volume: 1830
Issue: 4
Pages: 3082-94
Publication
First Author: Chao J
Year: 2017
Journal: Sci Rep
Title: Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization.
Volume: 7
Issue: 1
Pages: 11540
Publication  
First Author: Wang X
Year: 2018
Journal: Neurosci Lett
Title: Sigma 1 receptor mediated HMGB1 expression in spinal cord is involved in the development of diabetic neuropathic pain.
Volume: 668
Pages: 164-168
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:3759471
Age: embryonic day 18.5
Detected: true
Specimen Num: 19
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3759471
Age: embryonic day 15.5
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3759471
Age: embryonic day 13.5
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3759471
Age: embryonic day 11.5
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3759471
Age: embryonic day 9.5
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:3759471
Age: embryonic day 7.5
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:3759480
Assay Type: Western blot
Annotation Date: 2007-10-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:3759535
Age: postnatal
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3759480
Assay Type: Western blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:3759535
Age: postnatal
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3759480
Assay Type: Western blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:3759535
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Detected: true
Specimen Num: 2