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Search results 1 to 100 out of 250 for Sigmar1

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Hits by Strain

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Type Details Score
Gene
10280 | SIGMAR1
Type: gene
Organism: human
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Gene
465062 | SIGMAR1
Type: gene
Organism: chimpanzee
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Gene
538903 | SIGMAR1
Type: gene
Organism: cattle
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Gene
100859748 | SIGMAR1
Type: gene
Organism: chicken
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Gene
393952 | sigmar1
Type: gene
Organism: zebrafish
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Gene
700469 | SIGMAR1
Type: gene
Organism: macaque, rhesus
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Gene
493569 | sigmar1
Type: gene
Organism: frog, western clawed
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Gene
29336 | Sigmar1
Type: gene
Organism: rat
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Gene
481587 | SIGMAR1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1195268 | Sigmar1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
35633570 | J:340040
First Author: Huang L
Year: 2022
Journal: Genesis
Title: Generation of Sigmar1 conditional knockout mouse using CRISPR-Cas9 gene targeting.
Volume: 60
Issue: 6-7
Pages: e23487
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Publication
25678561 | J:243881
First Author: Bernard-Marissal N
Year: 2015
Journal: Brain
Title: Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration.
Volume: 138
Issue: Pt 4
Pages: 875-90
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Publication
37051024 | J:334754
 
First Author: Remex NS
Year: 2023
Journal: Front Physiol
Title: Sigmar1 ablation leads to lung pathological changes associated with pulmonary fibrosis, inflammation, and altered surfactant proteins levels.
Volume: 14
Pages: 1118770
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Publication
21862648 | J:181592
First Author: Ha Y
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).
Volume: 52
Issue: 10
Pages: 7749-60
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Publication
30371279 | J:282067
First Author: Abdullah CS
Year: 2018
Journal: J Am Heart Assoc
Title: Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics.
Volume: 7
Issue: 20
Pages: e009775
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Publication
34710383 | J:322121
First Author: Aishwarya R
Year: 2022
Journal: Am J Pathol
Title: Molecular Characterization of Skeletal Muscle Dysfunction in Sigma 1 Receptor (Sigmar1) Knockout Mice.
Volume: 192
Issue: 1
Pages: 160-177
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Publication
26868747 | J:257643
First Author: Zhao J
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: (+)-Pentazocine Reduces NMDA-Induced Murine Retinal Ganglion Cell Death Through a σR1-Dependent Mechanism.
Volume: 57
Issue: 2
Pages: 453-61
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Publication
25439327 | J:219837
First Author: Shanmugam A
Year: 2015
Journal: J Neurochem
Title: Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1γ, MIP2, MIP3α, and IL12 (p40/p70) by retinal Müller glial cells.
Volume: 132
Issue: 5
Pages: 546-58
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Publication
30871407 | J:284821
First Author: Yang H
Year: 2019
Journal: Autophagy
Title: SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance.
Volume: 15
Issue: 9
Pages: 1539-1557
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Publication
28350844 | J:246747
First Author: Pan L
Year: 2017
Journal: PLoS One
Title: Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.
Volume: 12
Issue: 3
Pages: e0174694
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Publication
21541278 | J:179534
 
First Author: Mavlyutov TA
Year: 2011
Journal: Mol Vis
Title: Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor.
Volume: 17
Pages: 1034-43
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Publication
17122151 | J:123094
First Author: Jiang G
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells.
Volume: 47
Issue: 12
Pages: 5576-82
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Publication
24469320 | J:321034
First Author: Ha Y
Year: 2014
Journal: Cell Tissue Res
Title: Sigma receptor 1 modulates ER stress and Bcl2 in murine retina.
Volume: 356
Issue: 1
Pages: 15-27
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Publication
33176836 | J:298984
First Author: Sánchez-Blázquez P
Year: 2020
Journal: Mol Brain
Title: The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception.
Volume: 13
Issue: 1
Pages: 150
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Publication
23233788 | J:192545
 
First Author: Ha Y
Year: 2012
Journal: Mol Vis
Title: Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1.
Volume: 18
Pages: 2860-70
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Publication
18469181 | J:141696
First Author: Smith SB
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine.
Volume: 49
Issue: 9
Pages: 4154-61
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Protein Coding Gene
MGP_129S1SvImJ_G0028171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028129 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028092 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028142 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027880 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1195268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027842 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027985 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028641 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024047 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026871 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9425306 | J:44925
First Author: Seth P
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor.
Volume: 241
Issue: 2
Pages: 535-40
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Publication
9603192 | J:47688
First Author: Pan YX
Year: 1998
Journal: J Neurochem
Title: Cloning and characterization of a mouse sigma1 receptor.
Volume: 70
Issue: 6
Pages: 2279-85
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Publication
14622179 | J:89669
First Author: Langa F
Year: 2003
Journal: Eur J Neurosci
Title: Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.
Volume: 18
Issue: 8
Pages: 2188-96
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Publication
20167253 | J:159702
First Author: Mavlyutov TA
Year: 2010
Journal: Neuroscience
Title: The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study.
Volume: 167
Issue: 2
Pages: 247-55
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Publication
23458708 | J:201365
 
First Author: Mavlyutov TA
Year: 2013
Journal: Neuroscience
Title: Lack of sigma-1 receptor exacerbates ALS progression in mice.
Volume: 240
Pages: 129-34
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Publication
24517272 | J:225243
 
First Author: Nieto FR
Year: 2014
Journal: Mol Pain
Title: Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice.
Volume: 10
Pages: 11
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Publication
34474349 | J:322081
 
First Author: López-Estévez S
Year: 2021
Journal: Biomed Pharmacother
Title: Intestinal inflammation-associated hypersensitivity is attenuated in a DSS model of colitis in Sigma-1 knockout C57BL/6 mice.
Volume: 143
Pages: 112126
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Publication
27260635 | J:235229
First Author: Snyder MA
Year: 2016
Journal: J Neurochem
Title: Sigma receptor type 1 knockout mice show a mild deficit in plasticity but no significant change in synaptic transmission in the CA1 region of the hippocampus.
Volume: 138
Issue: 5
Pages: 700-9
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Publication
36614024 | J:332614
 
First Author: Garzón-Niño J
Year: 2022
Journal: Int J Mol Sci
Title: (α)N-Acetyl β-Endorphin Is an Endogenous Ligand of σ1Rs That Regulates Mu-Opioid Receptor Signaling by Exchanging G Proteins for σ2Rs in σ1R Oligomers.
Volume: 24
Issue: 1
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Publication
20956312 | J:165484
First Author: Navarro G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine.
Volume: 107
Issue: 43
Pages: 18676-81
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Publication
19213917 | J:144935
First Author: Fontanilla D
Year: 2009
Journal: Science
Title: The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator.
Volume: 323
Issue: 5916
Pages: 934-7
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Publication
25143613 | J:216165
First Author: Pabba M
Year: 2014
Journal: J Neurosci
Title: NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus.
Volume: 34
Issue: 34
Pages: 11325-38
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Publication
31263413 | J:284429
 
First Author: Bravo-Caparrós I
Year: 2019
Journal: Front Pharmacol
Title: Sigma-1 Receptor Inhibition Reduces Neuropathic Pain Induced by Partial Sciatic Nerve Transection in Mice by Opioid-Dependent and -Independent Mechanisms.
Volume: 10
Pages: 613
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Publication
29497125 | J:262621
First Author: Castany S
Year: 2018
Journal: Sci Rep
Title: Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice.
Volume: 8
Issue: 1
Pages: 3873
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Publication
35406646 | J:334542
 
First Author: Cottilli P
Year: 2022
Journal: Cells
Title: Effects of Sigma-1 Receptor Ligands on Peripheral Nerve Regeneration.
Volume: 11
Issue: 7
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Publication
23632394 | J:277325
First Author: Vidal-Torres A
Year: 2013
Journal: Eur J Pharmacol
Title: Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects.
Volume: 711
Issue: 1-3
Pages: 63-72
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Publication
23524304 | J:214202
 
First Author: Sánchez-Fernández C
Year: 2013
Journal: Neuropharmacology
Title: Potentiation of morphine-induced mechanical antinociception by σ₁ receptor inhibition: role of peripheral σ₁ receptors.
Volume: 70
Pages: 348-58
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Publication
33385516 | J:307758
 
First Author: Vavers E
Year: 2021
Journal: Neurobiol Dis
Title: Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures.
Volume: 150
Pages: 105244
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Publication
34406331 | J:312283
First Author: Li L
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma.
Volume: 62
Issue: 10
Pages: 17
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Publication
18800345 | J:282440
First Author: Guzmán A
Year: 2008
Journal: Environ Mol Mutagen
Title: Induction of hypothermic conditions associated with increased micronuclei formation in sigma-1 receptor knockout mice after administration of the antipsychotic compound E-5842.
Volume: 49
Issue: 9
Pages: 727-33
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Publication
19100292 | J:145735
First Author: Sabino V
Year: 2009
Journal: Behav Brain Res
Title: Sigma-1 receptor knockout mice display a depressive-like phenotype.
Volume: 198
Issue: 2
Pages: 472-6
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Publication
28938641 | J:264951
First Author: Liu X
Year: 2017
Journal: Oncotarget
Title: Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel.
Volume: 8
Issue: 35
Pages: 59345-59358
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Publication
27339730 | J:238148
 
First Author: Mavlyutov TA
Year: 2016
Journal: Neuroscience
Title: Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody.
Volume: 331
Pages: 148-57
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Publication
26554014 | J:228062
First Author: Tsai SY
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.
Volume: 112
Issue: 47
Pages: E6562-70
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Publication
30756361 | J:287451
First Author: Francardo V
Year: 2019
Journal: Neurotherapeutics
Title: Pridopidine Induces Functional Neurorestoration Via the Sigma-1 Receptor in a Mouse Model of Parkinson's Disease.
Volume: 16
Issue: 2
Pages: 465-479
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Publication
35103752 | J:327719
First Author: Zhao J
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Sigma 1 Receptor Contributes to Astrocyte-Mediated Retinal Ganglion Cell Protection.
Volume: 63
Issue: 2
Pages: 1
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Publication
28108357 | J:272139
 
First Author: Zhang B
Year: 2017
Journal: Neuropharmacology
Title: Sigma-1 receptor deficiency reduces GABAergic inhibition in the basolateral amygdala leading to LTD impairment and depressive-like behaviors.
Volume: 116
Pages: 387-398
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Publication
28932185 | J:264916
 
First Author: Di T
Year: 2017
Journal: Front Mol Neurosci
Title: Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis Due to Dysfunction of the Hypothalamic Glucocorticoid Receptor in Sigma-1 Receptor Knockout Mice.
Volume: 10
Pages: 287
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Publication
21555330 | J:222357
First Author: Chevallier N
Year: 2011
Journal: J Psychopharmacol
Title: Behavioural phenotyping of knockout mice for the sigma-1 (σ₁) chaperone protein revealed gender-related anxiety, depressive-like and memory alterations.
Volume: 25
Issue: 7
Pages: 960-75
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Publication
28431607 | J:268962
 
First Author: Xu Q
Year: 2017
Journal: J Neurol Sci
Title: Sigma-1 receptor in brain ischemia/reperfusion: Possible role in the NR2A-induced pathway to regulate brain-derived neurotrophic factor.
Volume: 376
Pages: 166-175
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Publication
25920363 | J:315355
 
First Author: Wang J
Year: 2015
Journal: Free Radic Biol Med
Title: Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger.
Volume: 86
Pages: 25-36
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Publication
31108174 | J:282441
 
First Author: Eddings CR
Year: 2019
Journal: Neurobiol Dis
Title: Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor.
Volume: 129
Pages: 118-129
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Publication
32750415 | J:312525
 
First Author: Yang H
Year: 2020
Journal: Cell Signal
Title: Sigma-1 receptor ablation impedes adipocyte-like differentiation of mouse embryonic fibroblasts.
Volume: 75
Pages: 109732
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Publication
30006137 | J:268745
 
First Author: Liu DY
Year: 2018
Journal: Exp Neurol
Title: Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Volume: 308
Pages: 90-99
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Publication
24755275 | J:316459
First Author: Francardo V
Year: 2014
Journal: Brain
Title: Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism.
Volume: 137
Issue: Pt 7
Pages: 1998-2014
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Publication
29263318 | J:256524
First Author: Sambo DO
Year: 2017
Journal: Nat Commun
Title: The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission.
Volume: 8
Issue: 1
Pages: 2228
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Publication
21427517 | J:210796
First Author: Villard V
Year: 2011
Journal: J Pharmacol Sci
Title: Pharmacological interaction with the sigma1 (σ1)-receptor in the acute behavioral effects of antidepressants.
Volume: 115
Issue: 3
Pages: 279-92
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Publication
22381068 | J:264876
First Author: Pal A
Year: 2012
Journal: Eur J Pharmacol
Title: The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements.
Volume: 682
Issue: 1-3
Pages: 12-20
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Publication
23314020 | J:194984
First Author: Prause J
Year: 2013
Journal: Hum Mol Genet
Title: Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis.
Volume: 22
Issue: 8
Pages: 1581-600
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Publication
28723387 | J:249774
 
First Author: Tadić V
Year: 2017
Journal: Neuroscience
Title: Sigma 1 receptor activation modifies intracellular calcium exchange in the G93AhSOD1 ALS model.
Volume: 359
Pages: 105-118
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Publication
17981125 | J:182494
First Author: Hayashi T
Year: 2007
Journal: Cell
Title: Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival.
Volume: 131
Issue: 3
Pages: 596-610
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Publication
11434908 | J:70221
First Author: Mei J
Year: 2001
Journal: Biochem Pharmacol
Title: Molecular cloning and pharmacological characterization of the rat sigma1 receptor.
Volume: 62
Issue: 3
Pages: 349-55
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Publication
22619170 | J:188867
First Author: Shioda N
Year: 2012
Journal: J Biol Chem
Title: Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis.
Volume: 287
Issue: 28
Pages: 23318-31
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Publication
23298811 | J:199047
First Author: Tagashira H
Year: 2013
Journal: Biochim Biophys Acta
Title: Stimulation of σ1-receptor restores abnormal mitochondrial Ca²⁺ mobilization and ATP production following cardiac hypertrophy.
Volume: 1830
Issue: 4
Pages: 3082-94
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Publication
28912535 | J:255561
First Author: Chao J
Year: 2017
Journal: Sci Rep
Title: Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization.
Volume: 7
Issue: 1
Pages: 11540
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Publication
29421543 | J:257482
 
First Author: Wang X
Year: 2018
Journal: Neurosci Lett
Title: Sigma 1 receptor mediated HMGB1 expression in spinal cord is involved in the development of diabetic neuropathic pain.
Volume: 668
Pages: 164-168
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Publication
30387007 | J:295578
First Author: Zhao X
Year: 2019
Journal: Apoptosis
Title: Sigma-1 receptor protects against endoplasmic reticulum stress-mediated apoptosis in mice with cerebral ischemia/reperfusion injury.
Volume: 24
Issue: 1-2
Pages: 157-167
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Publication
31745133 | J:298447
First Author: Voronin MV
Year: 2019
Journal: Sci Rep
Title: Chaperone Sigma1R mediates the neuroprotective action of afobazole in the 6-OHDA model of Parkinson's disease.
Volume: 9
Issue: 1
Pages: 17020
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Publication
32157739 | J:305218
First Author: Bravo-Caparrós I
Year: 2020
Journal: FASEB J
Title: Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury.
Volume: 34
Issue: 4
Pages: 5951-5966
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Publication
32105755 | J:305839
 
First Author: González-Cano R
Year: 2020
Journal: Pharmacol Res
Title: Urinary bladder sigma-1 receptors: A new target for cystitis treatment.
Volume: 155
Pages: 104724
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Publication
31290080 | J:310492
First Author: Zhang Y
Year: 2020
Journal: Transl Stroke Res
Title: Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Volume: 11
Issue: 2
Pages: 267-287
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Publication
29177899 | J:318486
First Author: Bol'shakova AV
Year: 2017
Journal: Bull Exp Biol Med
Title: Neuroprotective Effect of σ1-Receptors on the Cell Model of Huntington's Disease.
Volume: 164
Issue: 2
Pages: 252-258
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Publication
36632219 | J:344507
First Author: Zhang G
Year: 2023
Journal: Theranostics
Title: Sigma-1 receptor-regulated efferocytosis by infiltrating circulating macrophages/microglial cells protects against neuronal impairments and promotes functional recovery in cerebral ischemic stroke.
Volume: 13
Issue: 2
Pages: 543-559
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GXD Expression
GXD Expression
     
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3759471
Age: postnatal adult
Specimen Label: S
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Specimen Label: Kidney +/+
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3759466
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3759469
Age: postnatal adult
Specimen Label: Kidney +/-
Detected: true
Specimen Num: 5
•
•
•
•
•




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