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Search results 1 to 100 out of 355 for Sirpa

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0.036s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Takenaka K
Year: 2007
Journal: Nat Immunol
Title: Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.
Volume: 8
Issue: 12
Pages: 1313-23
Publication
First Author: Morrissey MA
Year: 2020
Journal: Immunity
Title: CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.
Volume: 53
Issue: 2
Pages: 290-302.e6
Publication
First Author: Yamauchi T
Year: 2013
Journal: Blood
Title: Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.
Volume: 121
Issue: 8
Pages: 1316-25
Publication
First Author: Iwamoto C
Year: 2014
Journal: Exp Hematol
Title: The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.
Volume: 42
Issue: 3
Pages: 163-171.e1
Protein
Organism: Mus musculus
Length: 29  
Fragment?: true
Publication
First Author: Nuvolone M
Year: 2013
Journal: J Exp Med
Title: SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells.
Volume: 210
Issue: 12
Pages: 2539-52
Publication
First Author: Wang L
Year: 2012
Journal: J Neurochem
Title: SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress.
Volume: 122
Issue: 4
Pages: 834-43
Publication
First Author: Ring NG
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Volume: 114
Issue: 49
Pages: E10578-E10585
Publication
First Author: Wong AS
Year: 2014
Journal: J Immunol
Title: Polymorphism in the innate immune receptor SIRPα controls CD47 binding and autoimmunity in the nonobese diabetic mouse.
Volume: 193
Issue: 10
Pages: 4833-44
Publication
First Author: Jiang DS
Year: 2014
Journal: Hypertension
Title: Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling.
Volume: 63
Issue: 1
Pages: 96-104
Publication
First Author: Nuvolone M
Year: 2017
Journal: PLoS One
Title: Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling.
Volume: 12
Issue: 5
Pages: e0177876
Publication  
First Author: Dai H
Year: 2017
Journal: Sci Immunol
Title: Donor SIRPα polymorphism modulates the innate immune response to allogeneic grafts.
Volume: 2
Issue: 12
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Comu S
Year: 1997
Journal: J Neurosci
Title: The murine P84 neural adhesion molecule is SHPS-1, a member of the phosphatase-binding protein family.
Volume: 17
Issue: 22
Pages: 8702-10
Publication
First Author: Komori S
Year: 2019
Journal: Eur J Immunol
Title: SIRPα+ dendritic cells promote the development of fibroblastic reticular cells in murine peripheral lymph nodes.
Volume: 49
Issue: 9
Pages: 1364-1371
Publication
First Author: Washio K
Year: 2015
Journal: Genes Cells
Title: Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs.
Volume: 20
Issue: 6
Pages: 451-63
Publication
First Author: Wu J
Year: 2019
Journal: J Cachexia Sarcopenia Muscle
Title: Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk.
Volume: 10
Issue: 6
Pages: 1210-1227
Publication
First Author: Myers LM
Year: 2019
Journal: Nat Commun
Title: A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.
Volume: 10
Issue: 1
Pages: 794
Publication
First Author: Inagaki K
Year: 2000
Journal: EMBO J
Title: SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility.
Volume: 19
Issue: 24
Pages: 6721-31
Publication
First Author: Yamao T
Year: 2002
Journal: J Biol Chem
Title: Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.
Volume: 277
Issue: 42
Pages: 39833-9
Publication
First Author: Kobayashi M
Year: 2008
Journal: Endocrinology
Title: Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.
Volume: 149
Issue: 11
Pages: 5662-9
Publication
First Author: Ghimire K
Year: 2019
Journal: FASEB J
Title: Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.
Volume: 33
Issue: 10
Pages: 11528-11540
Publication
First Author: van Beek EM
Year: 2009
Journal: FASEB J
Title: Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.
Volume: 23
Issue: 12
Pages: 4081-90
Publication
First Author: Fukunaga A
Year: 2004
Journal: J Immunol
Title: Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes.
Volume: 172
Issue: 7
Pages: 4091-9
Publication
First Author: Takahashi S
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: SIRPα signaling regulates podocyte structure and function.
Volume: 305
Issue: 6
Pages: F861-70
Publication
First Author: Alvarez-Zarate J
Year: 2015
Journal: PLoS One
Title: Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.
Volume: 10
Issue: 6
Pages: e0127178
Publication
First Author: Okuzawa C
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Resistance to collagen-induced arthritis in SHPS-1 mutant mice.
Volume: 371
Issue: 3
Pages: 561-6
Publication
First Author: Morimoto N
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Requirement of SIRPα for protective immunity against Leishmania major.
Volume: 401
Issue: 3
Pages: 385-9
Publication
First Author: Wang J
Year: 2019
Journal: Glia
Title: SIRPα deficiency accelerates the pathologic process in models of Parkinson disease.
Volume: 67
Issue: 12
Pages: 2343-2359
Publication
First Author: Tomizawa T
Year: 2007
Journal: J Immunol
Title: Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice.
Volume: 179
Issue: 2
Pages: 869-77
Publication
First Author: Fukunaga A
Year: 2006
Journal: Eur J Immunol
Title: Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation.
Volume: 36
Issue: 12
Pages: 3216-26
Publication
First Author: van Beek EM
Year: 2012
Journal: Cell Rep
Title: SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).
Volume: 2
Issue: 4
Pages: 748-55
Publication
First Author: Ishikawa-Sekigami T
Year: 2006
Journal: Blood
Title: SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages.
Volume: 107
Issue: 1
Pages: 341-8
Publication
First Author: Okajo J
Year: 2007
Journal: J Immunol
Title: Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells.
Volume: 178
Issue: 10
Pages: 6164-72
Publication
First Author: Nagappan-Chettiar S
Year: 2018
Journal: J Biol Chem
Title: Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation.
Volume: 293
Issue: 31
Pages: 12026-12042
Publication
First Author: Elberg G
Year: 2019
Journal: J Neuroinflammation
Title: Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury.
Volume: 16
Issue: 1
Pages: 277
Publication
First Author: Zhu D
Year: 2013
Journal: J Allergy Clin Immunol
Title: MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein α.
Volume: 132
Issue: 2
Pages: 426-36.e8
Publication
First Author: Fujioka Y
Year: 1996
Journal: Mol Cell Biol
Title: A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion.
Volume: 16
Issue: 12
Pages: 6887-99
Publication
First Author: Sano S
Year: 1997
Journal: FEBS Lett
Title: BIT, an immune antigen receptor-like molecule in the brain.
Volume: 411
Issue: 2-3
Pages: 327-34
Publication
First Author: Massa PT
Year: 2002
Journal: J Virol
Title: Critical role for protein tyrosine phosphatase SHP-1 in controlling infection of central nervous system glia and demyelination by Theiler's murine encephalomyelitis virus.
Volume: 76
Issue: 16
Pages: 8335-46
Publication
First Author: Miyake A
Year: 2008
Journal: Genes Cells
Title: Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages.
Volume: 13
Issue: 2
Pages: 209-19
Publication
First Author: Ikeda H
Year: 2006
Journal: J Immunol
Title: Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.
Volume: 177
Issue: 5
Pages: 3123-32
Publication
First Author: Maruyama T
Year: 2012
Journal: J Neurochem
Title: Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain.
Volume: 121
Issue: 6
Pages: 891-902
Publication
First Author: Baral P
Year: 2012
Journal: Infect Immun
Title: Involvement of signal regulatory protein α, a negative regulator of Toll-like receptor signaling, in impairing the MyD88-independent pathway and intracellular killing of Burkholderia pseudomallei-infected mouse macrophages.
Volume: 80
Issue: 12
Pages: 4223-31
Publication
First Author: Pan YF
Year: 2013
Journal: Eur J Immunol
Title: Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation.
Volume: 43
Issue: 6
Pages: 1598-607
Publication
First Author: Kolan SS
Year: 2015
Journal: PLoS One
Title: Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen.
Volume: 10
Issue: 7
Pages: e0134113
Publication
First Author: Nishimura T
Year: 2020
Journal: Eur J Immunol
Title: SIRPα on CD11c+ cells induces Th17 cell differentiation and subsequent inflammation in the CNS in experimental autoimmune encephalomyelitis.
Volume: 50
Issue: 10
Pages: 1560-1570
Publication    
First Author: Li L
Year: 2019
Journal: JCI Insight
Title: Signal regulatory protein α protects podocytes through promoting autophagic activity.
Volume: 5
Publication
First Author: Ding X
Year: 2021
Journal: Nat Commun
Title: Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.
Volume: 12
Issue: 1
Pages: 2030
GXD Expression    
Probe: MGI:6473528
Assay Type: RT-PCR
Annotation Date: 2020-11-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716824
Stage: TS24
Assay Id: MGI:6474125
Age: embryonic day 16.0
Image: 4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6473528
Assay Type: RT-PCR
Annotation Date: 2020-11-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6474125
Age: postnatal day 2
Image: 4
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6473528
Assay Type: RT-PCR
Annotation Date: 2020-11-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6474125
Age: postnatal day 14
Image: 4
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6473528
Assay Type: RT-PCR
Annotation Date: 2020-11-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6474125
Age: postnatal week 14
Image: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3029496
Assay Type: Northern blot
Annotation Date: 2004-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3029898
Age: embryonic day 7.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3029496
Assay Type: Northern blot
Annotation Date: 2004-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3029898
Age: embryonic day 11.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3029496
Assay Type: Northern blot
Annotation Date: 2004-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3029898
Age: embryonic day 15.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3029496
Assay Type: Northern blot
Annotation Date: 2004-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3029898
Age: embryonic day 17.0
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945026
Age: embryonic day 11.5
Image: g00472 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945026
Age: embryonic day 15.5
Image: g00472 E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398076
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398077
Detected: true
Specimen Num: 13
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398074
Note: kidney
Detected: true
Specimen Num: 10
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398075
Note: kidney
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945026
Age: embryonic day 15.5
Image: g00472 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945026
Age: postnatal day 7
Image: g00472 P7
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398076
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398077
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6473962
Age: postnatal week 16
Image: 1d
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6473794
Assay Type: RNA in situ
Annotation Date: 2020-11-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6474018
Age: postnatal day 14
Image: 3 P14
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6473794
Assay Type: RNA in situ
Annotation Date: 2020-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6474018
Age: postnatal week 14
Image: 3 14w
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398076
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691140
Age: postnatal adult
Image: BCM_2398077
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945026
Age: embryonic day 11.5
Image: g00472 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945026
Age: embryonic day 15.5
Image: g00472 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886246
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945026
Age: postnatal day 7
Image: g00472 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5616094
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5616107
Age: embryonic day 10.5
Image: 5E
Note: Authors describe expression as marking ventral cells.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5616094
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5616107
Age: embryonic day 10.5
Image: 5F
Note: Expanded region of expression in mutants compared to wildtype embryos.
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6473962
Age: postnatal week 16
Image: 1d
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6473794
Assay Type: RNA in situ
Annotation Date: 2020-11-25
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3574128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6474018
Age: postnatal day 14
Image: 3 P14
Detected: true
Specimen Num: 3