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Search results 1 to 100 out of 305 for Sirt2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Jing E
Year: 2007
Journal: Cell Metab
Title: SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation.
Volume: 6
Issue: 2
Pages: 105-14
Publication
First Author: Newton K
Year: 2014
Journal: Nature
Title: Is SIRT2 required for necroptosis?
Volume: 506
Issue: 7489
Pages: E4-6
Publication
First Author: Lin J
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
Volume: 441
Issue: 4
Pages: 897-903
Publication
First Author: Seo KS
Year: 2015
Journal: Oncogene
Title: SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation.
Volume: 34
Issue: 11
Pages: 1354-62
Publication
First Author: Wang M
Year: 2022
Journal: Nat Commun
Title: Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation.
Volume: 13
Issue: 1
Pages: 4494
Publication
First Author: Narayan N
Year: 2012
Journal: Nature
Title: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Volume: 492
Issue: 7428
Pages: 199-204
Publication
First Author: Zhu H
Year: 2012
Journal: Glia
Title: The QKI-PLP pathway controls SIRT2 abundance in CNS myelin.
Volume: 60
Issue: 1
Pages: 69-82
Publication
First Author: Lo Sasso G
Year: 2014
Journal: PLoS One
Title: SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis.
Volume: 9
Issue: 7
Pages: e103573
Publication
First Author: Arora A
Year: 2014
Journal: Biochim Biophys Acta
Title: SIRT2 negatively regulates insulin resistance in C2C12 skeletal muscle cells.
Volume: 1842
Issue: 9
Pages: 1372-8
Publication
First Author: Sarikhani M
Year: 2018
Journal: J Biol Chem
Title: SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis.
Volume: 293
Issue: 14
Pages: 5281-5294
Publication
First Author: Lantier L
Year: 2018
Journal: PLoS One
Title: SIRT2 knockout exacerbates insulin resistance in high fat-fed mice.
Volume: 13
Issue: 12
Pages: e0208634
Publication
First Author: Southwood CM
Year: 2007
Journal: Neurochem Res
Title: Microtubule deacetylases, SirT2 and HDAC6, in the nervous system.
Volume: 32
Issue: 2
Pages: 187-95
Publication
First Author: Watanabe H
Year: 2018
Journal: Nat Commun
Title: Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein.
Volume: 9
Issue: 1
Pages: 30
Publication
First Author: Tang X
Year: 2017
Journal: Circulation
Title: SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy.
Volume: 136
Issue: 21
Pages: 2051-2067
Publication
First Author: Zhang M
Year: 2021
Journal: Sci Rep
Title: SIRT2 promotes murine melanoma progression through natural killer cell inhibition.
Volume: 11
Issue: 1
Pages: 12988
Publication  
First Author: Muñoz-Cobo I
Year: 2017
Journal: Behav Brain Res
Title: SIRT2 inhibition reverses anhedonia in the VGLUT1+/- depression model.
Volume: 335
Pages: 128-131
Publication
First Author: Jung YJ
Year: 2015
Journal: J Am Soc Nephrol
Title: SIRT2 Regulates LPS-Induced Renal Tubular CXCL2 and CCL2 Expression.
Volume: 26
Issue: 7
Pages: 1549-60
Publication
First Author: North BJ
Year: 2014
Journal: EMBO J
Title: SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.
Volume: 33
Issue: 13
Pages: 1438-53
Publication    
First Author: Sarikhani M
Year: 2018
Journal: Elife
Title: SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation.
Volume: 7
Publication
First Author: Xie XQ
Year: 2017
Journal: Mol Neurobiol
Title: Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke.
Volume: 54
Issue: 9
Pages: 7251-7261
Publication
First Author: Zhang L
Year: 2014
Journal: FASEB J
Title: Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis.
Volume: 28
Issue: 3
Pages: 1435-45
Publication
First Author: Song HY
Year: 2016
Journal: Oncotarget
Title: SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status.
Volume: 7
Issue: 49
Pages: 80336-80349
Publication
First Author: Hamaidi I
Year: 2020
Journal: Cell Metab
Title: Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells.
Volume: 32
Issue: 3
Pages: 420-436.e12
Publication
First Author: Kim HS
Year: 2011
Journal: Cancer Cell
Title: SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.
Volume: 20
Issue: 4
Pages: 487-99
Publication
First Author: Bai N
Year: 2022
Journal: Cell Rep
Title: Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.
Volume: 40
Issue: 2
Pages: 111062
Publication
First Author: Wang G
Year: 2017
Journal: Cell Rep
Title: Crucial Roles for SIRT2 and AMPA Receptor Acetylation in Synaptic Plasticity and Memory.
Volume: 20
Issue: 6
Pages: 1335-1347
Publication
First Author: Ming M
Year: 2014
Journal: Exp Dermatol
Title: Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin.
Volume: 23
Issue: 3
Pages: 207-9
Publication
First Author: Vaquero A
Year: 2006
Journal: Genes Dev
Title: SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis.
Volume: 20
Issue: 10
Pages: 1256-61
Publication
First Author: Wang F
Year: 2007
Journal: Aging Cell
Title: SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction.
Volume: 6
Issue: 4
Pages: 505-14
Publication  
First Author: Schmidt AV
Year: 2023
Journal: Int J Mol Sci
Title: A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma.
Volume: 24
Issue: 16
Publication
First Author: Kim AY
Year: 2018
Journal: Cell Death Dis
Title: SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency.
Volume: 9
Issue: 9
Pages: 893
Publication  
First Author: Hao C
Year: 2022
Journal: Biochem Biophys Res Commun
Title: SIRT2 regulates proliferation and chemotherapy response of MLL-ENL-driven acute myeloid leukemia.
Volume: 596
Pages: 36-42
Publication  
First Author: Leal H
Year: 2022
Journal: Int J Mol Sci
Title: SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway.
Volume: 23
Issue: 12
Publication
First Author: Fourcade S
Year: 2017
Journal: Aging Cell
Title: Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.
Volume: 16
Issue: 6
Pages: 1404-1413
Publication
First Author: Sarikhani M
Year: 2018
Journal: Cell Death Differ
Title: SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH2-terminal kinase.
Volume: 25
Issue: 9
Pages: 1638-1656
Publication
First Author: Li C
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and Differentiation.
Volume: 10
Issue: 1
Pages: 43-57
Publication
First Author: Hao L
Year: 2021
Journal: J Invest Dermatol
Title: Inhibiting Protein Kinase Activity of Pyruvate Kinase M2 by SIRT2 Deacetylase Attenuates Psoriasis.
Volume: 141
Issue: 2
Pages: 355-363.e6
Publication
First Author: Nagai T
Year: 2013
Journal: J Cell Sci
Title: Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase.
Volume: 126
Issue: Pt 19
Pages: 4369-80
Publication
First Author: Rothgiesser KM
Year: 2010
Journal: J Cell Sci
Title: SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310.
Volume: 123
Issue: Pt 24
Pages: 4251-8
Publication
First Author: Lemos V
Year: 2017
Journal: Hum Mol Genet
Title: The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes.
Volume: 26
Issue: 21
Pages: 4105-4117
Publication
First Author: Zhou X
Year: 2014
Journal: Hum Mol Genet
Title: SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.
Volume: 23
Issue: 6
Pages: 1644-55
Publication
First Author: Zhang Z
Year: 2018
Journal: Biochim Biophys Acta
Title: CDK5-mediated phosphorylation of Sirt2 contributes to depressive-like behavior induced by social defeat stress.
Volume: 1864
Issue: 2
Pages: 533-541
Publication
First Author: Snider NT
Year: 2013
Journal: J Cell Biol
Title: Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation.
Volume: 200
Issue: 3
Pages: 241-7
Publication
First Author: Si X
Year: 2013
Journal: PLoS One
Title: Activation of GSK3β by Sirt2 is required for early lineage commitment of mouse embryonic stem cell.
Volume: 8
Issue: 10
Pages: e76699
Publication
First Author: Nguyen P
Year: 2014
Journal: Mol Cancer Res
Title: SIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stress.
Volume: 12
Issue: 9
Pages: 1244-53
Publication
First Author: Wang F
Year: 2009
Journal: Mol Biol Cell
Title: SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma.
Volume: 20
Issue: 3
Pages: 801-8
Publication
First Author: Serrano L
Year: 2013
Journal: Genes Dev
Title: The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation.
Volume: 27
Issue: 6
Pages: 639-53
Publication
First Author: Liemburg-Apers DC
Year: 2016
Journal: J Cell Sci
Title: Acute stimulation of glucose influx upon mitoenergetic dysfunction requires LKB1, AMPK, Sirt2 and mTOR-RAPTOR.
Volume: 129
Issue: 23
Pages: 4411-4423
Publication  
First Author: Schartner E
Year: 2018
Journal: Exp Neurol
Title: High glucose concentration suppresses a SIRT2 regulated pathway that enhances neurite outgrowth in cultured adult sensory neurons.
Volume: 309
Pages: 134-147
Publication  
First Author: Heinonen T
Year: 2019
Journal: Front Immunol
Title: Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia.
Volume: 10
Pages: 2713
Publication
First Author: Quan S
Year: 2018
Journal: Sci Rep
Title: Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice.
Volume: 8
Issue: 1
Pages: 16501
Publication
First Author: Bobrowska A
Year: 2012
Journal: PLoS One
Title: SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo.
Volume: 7
Issue: 4
Pages: e34805
Publication
First Author: Wang YP
Year: 2014
Journal: EMBO J
Title: Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress.
Volume: 33
Issue: 12
Pages: 1304-20
Publication
First Author: Nguyen P
Year: 2019
Journal: Radiat Res
Title: Sirt2 Regulates Radiation-Induced Injury.
Volume: 191
Issue: 5
Pages: 398-412
Publication
First Author: Thangaraj MP
Year: 2017
Journal: J Biol Chem
Title: RNA-binding Protein Quaking Stabilizes Sirt2 mRNA during Oligodendroglial Differentiation.
Volume: 292
Issue: 13
Pages: 5166-5182
Publication
First Author: Chopra V
Year: 2012
Journal: Cell Rep
Title: The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models.
Volume: 2
Issue: 6
Pages: 1492-7
Publication  
First Author: Szegő ÉM
Year: 2017
Journal: Neurobiol Aging
Title: Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway.
Volume: 56
Pages: 7-16
Publication
First Author: Eldridge MJG
Year: 2021
Journal: PLoS Pathog
Title: Histone H3 deacetylation promotes host cell viability for efficient infection by Listeria monocytogenes.
Volume: 17
Issue: 12
Pages: e1010173
Publication
First Author: Eskandarian HA
Year: 2013
Journal: Science
Title: A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.
Volume: 341
Issue: 6145
Pages: 1238858
Publication
First Author: Suzuki K
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Resveratrol abolishes resistance to axonal degeneration in slow Wallerian degeneration (WldS) mice: activation of SIRT2, an NAD-dependent tubulin deacetylase.
Volume: 359
Issue: 3
Pages: 665-71
Publication  
First Author: Lee YG
Year: 2019
Journal: JCI Insight
Title: Sirtuin 2 enhances allergic asthmatic inflammation.
Volume: 4
Issue: 4
Publication
First Author: Chamberlain KA
Year: 2021
Journal: Neuron
Title: Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2.
Volume: 109
Issue: 21
Pages: 3456-3472.e8
Publication  
First Author: Sa de Almeida J
Year: 2020
Journal: Front Neurosci
Title: Microglial Sirtuin 2 Shapes Long-Term Potentiation in Hippocampal Slices.
Volume: 14
Pages: 614
Publication
First Author: Belman JP
Year: 2015
Journal: J Biol Chem
Title: Acetylation of TUG protein promotes the accumulation of GLUT4 glucose transporters in an insulin-responsive intracellular compartment.
Volume: 290
Issue: 7
Pages: 4447-63
Publication
First Author: Silva DF
Year: 2017
Journal: Mol Neurobiol
Title: Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer's-Disease Related Pathology.
Volume: 54
Issue: 6
Pages: 4021-4040
Publication
First Author: Pais TF
Year: 2013
Journal: EMBO J
Title: The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation.
Volume: 32
Issue: 19
Pages: 2603-16
Publication
First Author: Liu L
Year: 2012
Journal: J Biol Chem
Title: Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein.
Volume: 287
Issue: 39
Pages: 32307-11
Publication
First Author: Chen M
Year: 2019
Journal: Cancer Immunol Immunother
Title: Sirtuin2 enhances the tumoricidal function of liver natural killer cells in a mouse hepatocellular carcinoma model.
Volume: 68
Issue: 6
Pages: 961-971
Publication
First Author: Diaz-Perdigon T
Year: 2020
Journal: Neuropsychopharmacology
Title: Early sirtuin 2 inhibition prevents age-related cognitive decline in a senescence-accelerated mouse model.
Volume: 45
Issue: 2
Pages: 347-357
Publication
First Author: Krishnan J
Year: 2012
Journal: Genes Dev
Title: Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.
Volume: 26
Issue: 3
Pages: 259-70
Publication  
First Author: Qiu D
Year: 2018
Journal: Aging Cell
Title: Sirt2-BubR1 acetylation pathway mediates the effects of advanced maternal age on oocyte quality.
Volume: 17
Issue: 1
Publication
First Author: Beirowski B
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.
Volume: 108
Issue: 43
Pages: E952-61
Publication
First Author: He M
Year: 2020
Journal: Cell Metab
Title: An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance.
Volume: 31
Issue: 3
Pages: 580-591.e5
Publication  
First Author: Gandhirajan A
Year: 2022
Journal: Front Immunol
Title: SIRT2-PFKP interaction dysregulates phagocytosis in macrophages with acute ethanol-exposure.
Volume: 13
Pages: 1079962
Publication
First Author: Mei ZL
Year: 2020
Journal: Exp Cell Res
Title: CSN6 aggravates Ang II-induced cardiomyocyte hypertrophy via inhibiting SIRT2.
Volume: 396
Issue: 1
Pages: 112245
Publication
First Author: Luo H
Year: 2019
Journal: Cell Rep
Title: Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging.
Volume: 26
Issue: 4
Pages: 945-954.e4
Publication
First Author: Yang X
Year: 2017
Journal: J Clin Invest
Title: Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.
Volume: 127
Issue: 4
Pages: 1505-1516
Publication  
First Author: Buechler N
Year: 2017
Journal: J Immunol Res
Title: Sirtuin 2 Regulates Microvascular Inflammation during Sepsis.
Volume: 2017
Pages: 2648946
Publication    
First Author: Wang Y
Year: 2020
Journal: Aging Cell
Title: RTN4B-mediated suppression of Sirtuin 2 activity ameliorates β-amyloid pathology and cognitive impairment in Alzheimer's disease mouse model.
Pages: e13194
Publication
First Author: Yang W
Year: 2013
Journal: Biochem J
Title: Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulin.
Volume: 449
Issue: 3
Pages: 605-12
Publication
First Author: Taes I
Year: 2013
Journal: Hum Mol Genet
Title: Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS.
Volume: 22
Issue: 9
Pages: 1783-90
Publication
First Author: Kosciuczuk EM
Year: 2019
Journal: J Biol Chem
Title: Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.
Volume: 294
Issue: 3
Pages: 827-837
Publication
First Author: Wang X
Year: 2016
Journal: PLoS One
Title: Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
Volume: 11
Issue: 8
Pages: e0160431
Publication  
First Author: Shimizu K
Year: 2016
Journal: Exp Neurol
Title: Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels.
Volume: 275 Pt 1
Pages: 78-83
Publication
First Author: Movahedi Naini S
Year: 2015
Journal: Mol Cell Biol
Title: Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.
Volume: 35
Issue: 21
Pages: 3768-84
Publication
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
Publication
First Author: Maxwell MM
Year: 2011
Journal: Hum Mol Genet
Title: The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS.
Volume: 20
Issue: 20
Pages: 3986-96
Publication
First Author: Orpinell M
Year: 2010
Journal: EMBO J
Title: The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.
Volume: 29
Issue: 14
Pages: 2381-94
Publication
First Author: Werner HB
Year: 2007
Journal: J Neurosci
Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Volume: 27
Issue: 29
Pages: 7717-30
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli