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Search results 1 to 100 out of 393 for Sirt3

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Brown K
Year: 2013
Journal: Cell Rep
Title: SIRT3 reverses aging-associated degeneration.
Volume: 3
Issue: 2
Pages: 319-27
Publication
First Author: Yang Y
Year: 2011
Journal: Gene
Title: Murine Sirt3 protein isoforms have variable half-lives.
Volume: 488
Issue: 1-2
Pages: 46-51
Publication
First Author: Dittenhafer-Reed KE
Year: 2015
Journal: Cell Metab
Title: SIRT3 mediates multi-tissue coupling for metabolic fuel switching.
Volume: 21
Issue: 4
Pages: 637-46
Publication  
First Author: Kristian T
Year: 2021
Journal: Cells
Title: Perturbed Brain Glucose Metabolism Caused by Absent SIRT3 Activity.
Volume: 10
Issue: 9
Publication
First Author: Yang X
Year: 2018
Journal: CNS Neurosci Ther
Title: Sirt3 deficiency impairs neurovascular recovery in ischemic stroke.
Volume: 24
Issue: 9
Pages: 775-783
Publication
First Author: Finley LW
Year: 2011
Journal: Cancer Cell
Title: SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.
Volume: 19
Issue: 3
Pages: 416-28
Publication
First Author: Hirschey MD
Year: 2010
Journal: Nature
Title: SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Volume: 464
Issue: 7285
Pages: 121-5
Publication
First Author: Verma R
Year: 2019
Journal: Transl Stroke Res
Title: Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke.
Volume: 10
Issue: 1
Pages: 57-66
Publication  
First Author: Kurundkar D
Year: 2019
Journal: JCI Insight
Title: SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury.
Volume: 4
Issue: 1
Publication
First Author: Tyagi A
Year: 2018
Journal: Sci Rep
Title: SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain.
Volume: 8
Issue: 1
Pages: 17547
Publication  
First Author: Zhao W
Year: 2018
Journal: Front Physiol
Title: SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy.
Volume: 9
Pages: 1526
Publication
First Author: Koentges C
Year: 2015
Journal: Basic Res Cardiol
Title: SIRT3 deficiency impairs mitochondrial and contractile function in the heart.
Volume: 110
Issue: 4
Pages: 36
Publication
First Author: Cimen H
Year: 2010
Journal: Biochemistry
Title: Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria.
Volume: 49
Issue: 2
Pages: 304-11
Publication
First Author: Cui Y
Year: 2015
Journal: PLoS One
Title: SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells.
Volume: 10
Issue: 6
Pages: e0129834
Publication  
First Author: Shi Z
Year: 2018
Journal: Biomed Res Int
Title: Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction.
Volume: 2018
Pages: 2708491
Publication
First Author: Wu J
Year: 2020
Journal: Lab Invest
Title: Polydatin protects against lipopolysaccharide-induced endothelial barrier disruption via SIRT3 activation.
Volume: 100
Issue: 4
Pages: 643-656
Publication
First Author: Li M
Year: 2019
Journal: Cancer Cell
Title: Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Volume: 35
Issue: 6
Pages: 916-931.e9
Publication
First Author: Shi H
Year: 2017
Journal: Hum Mol Genet
Title: Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress.
Volume: 26
Issue: 10
Pages: 1915-1926
Publication
First Author: Porter GA
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts.
Volume: 306
Issue: 12
Pages: H1602-9
Publication
First Author: Lee D
Year: 2020
Journal: Arch Pharm Res
Title: Dietary schizophyllan reduces mitochondrial damage by activating SIRT3 in mice.
Volume: 43
Issue: 4
Pages: 449-461
Publication
First Author: Lombard DB
Year: 2007
Journal: Mol Cell Biol
Title: Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Volume: 27
Issue: 24
Pages: 8807-14
Publication
First Author: Hebert AS
Year: 2013
Journal: Mol Cell
Title: Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
Volume: 49
Issue: 1
Pages: 186-99
Publication
First Author: Jing E
Year: 2013
Journal: Diabetes
Title: Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.
Volume: 62
Issue: 10
Pages: 3404-17
Publication
First Author: Shimazu T
Year: 2010
Journal: Cell Metab
Title: SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.
Volume: 12
Issue: 6
Pages: 654-61
Publication
First Author: Weinert BT
Year: 2015
Journal: EMBO J
Title: Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions.
Volume: 34
Issue: 21
Pages: 2620-32
Publication
First Author: Weir HJ
Year: 2012
Journal: PLoS One
Title: CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease.
Volume: 7
Issue: 11
Pages: e48225
Publication
First Author: Dikalova AE
Year: 2017
Journal: Circ Res
Title: Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension.
Volume: 121
Issue: 5
Pages: 564-574
Publication
First Author: Kim HS
Year: 2010
Journal: Cancer Cell
Title: SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.
Volume: 17
Issue: 1
Pages: 41-52
Publication
First Author: Cheng A
Year: 2016
Journal: Cell Metab
Title: Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges.
Volume: 23
Issue: 1
Pages: 128-42
Publication  
First Author: He P
Year: 2018
Journal: Mol Cell Endocrinol
Title: SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
Volume: 460
Pages: 1-13
Publication
First Author: Someya S
Year: 2010
Journal: Cell
Title: Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.
Volume: 143
Issue: 5
Pages: 802-12
Publication
First Author: Brown KD
Year: 2014
Journal: Cell Metab
Title: Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss.
Volume: 20
Issue: 6
Pages: 1059-68
Publication  
First Author: Fernandez-Marcos PJ
Year: 2012
Journal: Sci Rep
Title: Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis.
Volume: 2
Pages: 425
Publication
First Author: Zhou TY
Year: 2019
Journal: Eur Rev Med Pharmacol Sci
Title: SIRT3 retards intervertebral disc degeneration by anti-oxidative stress by activating the SIRT3/FOXO3/SOD2 signaling pathway.
Volume: 23
Issue: 21
Pages: 9180-9188
Publication
First Author: Cooper HM
Year: 2009
Journal: PLoS One
Title: A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein.
Volume: 4
Issue: 3
Pages: e4986
Publication
First Author: Iljas JD
Year: 2020
Journal: FASEB J
Title: Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice.
Volume: 34
Issue: 5
Pages: 6641-6653
Publication
First Author: Jablonski RP
Year: 2017
Journal: FASEB J
Title: SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis.
Volume: 31
Issue: 6
Pages: 2520-2532
Publication  
First Author: Li R
Year: 2019
Journal: Free Radic Biol Med
Title: Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Volume: 135
Pages: 116-124
Publication  
First Author: Cheresh P
Year: 2021
Journal: Int J Mol Sci
Title: SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment.
Volume: 22
Issue: 13
Publication  
First Author: He X
Year: 2017
Journal: J Mol Cell Cardiol
Title: Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction.
Volume: 112
Pages: 104-113
Publication  
First Author: Li Q
Year: 2021
Journal: Bone
Title: Deletion of SIRT3 inhibits osteoclastogenesis and alleviates aging or estrogen deficiency-induced bone loss in female mice.
Volume: 144
Pages: 115827
Publication
First Author: Zeng H
Year: 2014
Journal: PLoS One
Title: Loss of Sirt3 limits bone marrow cell-mediated angiogenesis and cardiac repair in post-myocardial infarction.
Volume: 9
Issue: 9
Pages: e107011
Publication
First Author: Bindu S
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage.
Volume: 312
Issue: 1
Pages: L68-L78
Publication  
First Author: Pinterić M
Year: 2021
Journal: Int J Mol Sci
Title: Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice.
Volume: 22
Issue: 8
Publication
First Author: Pillai VB
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.
Volume: 310
Issue: 8
Pages: H962-72
Publication  
First Author: He X
Year: 2016
Journal: Int J Cardiol
Title: Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia.
Volume: 215
Pages: 349-57
Publication
First Author: Jeong SM
Year: 2015
Journal: Oncogene
Title: SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1.
Volume: 34
Issue: 16
Pages: 2115-24
Publication  
First Author: Yang L
Year: 2016
Journal: Sci Rep
Title: SIRT3 Deficiency Induces Endothelial Insulin Resistance and Blunts Endothelial-Dependent Vasorelaxation in Mice and Human with Obesity.
Volume: 6
Pages: 23366
Publication  
First Author: Sebaa R
Year: 2019
Journal: Mol Metab
Title: SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1.
Volume: 25
Pages: 35-49
Publication  
First Author: Matoba H
Year: 2024
Journal: Endocrinology
Title: Sirt3 Regulates Proliferation and Progesterone Production in Leydig Cells via Suppression of Reactive Oxygen Species.
Volume: 165
Issue: 4
Publication
First Author: Liang Q
Year: 2013
Journal: Biochem J
Title: Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts.
Volume: 454
Issue: 2
Pages: 249-57
Publication
First Author: Ramachandran D
Year: 2017
Journal: Mol Metab
Title: Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight.
Volume: 6
Issue: 10
Pages: 1264-1273
Publication  
First Author: Ling W
Year: 2021
Journal: JCI Insight
Title: Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency.
Volume: 6
Issue: 10
Publication  
First Author: Liu J
Year: 2019
Journal: Cell Signal
Title: Sirt3 attenuates post-infarction cardiac injury via inhibiting mitochondrial fission and normalization of AMPK-Drp1 pathways.
Volume: 53
Pages: 1-13
Publication
First Author: Li J
Year: 2016
Journal: Oncotarget
Title: Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1.
Volume: 7
Issue: 52
Pages: 86648-86659
Publication  
First Author: Su H
Year: 2023
Journal: Cells
Title: SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation.
Volume: 12
Issue: 10
Publication
First Author: Nakamura Y
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5.
Volume: 366
Issue: 1
Pages: 174-9
Publication
First Author: Cheng A
Year: 2020
Journal: J Neurosci
Title: SIRT3 Haploinsufficiency Aggravates Loss of GABAergic Interneurons and Neuronal Network Hyperexcitability in an Alzheimer's Disease Model.
Volume: 40
Issue: 3
Pages: 694-709
Publication
First Author: Novgorodov SA
Year: 2016
Journal: J Biol Chem
Title: SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
Volume: 291
Issue: 4
Pages: 1957-73
Publication  
First Author: Wang M
Year: 2023
Journal: Redox Biol
Title: SIRT3 improved peroxisomes-mitochondria interplay and prevented cardiac hypertrophy via preserving PEX5 expression.
Volume: 62
Pages: 102652
Publication
First Author: Hirschey MD
Year: 2011
Journal: Mol Cell
Title: SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.
Volume: 44
Issue: 2
Pages: 177-90
Publication  
First Author: Guo M
Year: 2023
Journal: Front Immunol
Title: SIRT3 alleviates imiquimod-induced psoriatic dermatitis through deacetylation of XBP1s and modulation of TLR7/8 inducing IL-23 production in macrophages.
Volume: 14
Pages: 1128543
Publication
First Author: Perico L
Year: 2021
Journal: Sci Rep
Title: Post-translational modifications by SIRT3 de-2-hydroxyisobutyrylase activity regulate glycolysis and enable nephrogenesis.
Volume: 11
Issue: 1
Pages: 23580
Publication
First Author: Ahn BH
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis.
Volume: 105
Issue: 38
Pages: 14447-52
Publication
First Author: Yue Z
Year: 2016
Journal: Exp Cell Res
Title: NMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy.
Volume: 347
Issue: 2
Pages: 261-73
Publication  
First Author: Heinonen T
Year: 2019
Journal: Front Immunol
Title: Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses.
Volume: 10
Pages: 2341
Publication
First Author: Chen T
Year: 2015
Journal: PLoS One
Title: Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD.
Volume: 10
Issue: 3
Pages: e0118909
Publication
First Author: Yang Y
Year: 2010
Journal: J Biol Chem
Title: NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10.
Volume: 285
Issue: 10
Pages: 7417-29
Publication
First Author: Rardin MJ
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Volume: 110
Issue: 16
Pages: 6601-6
Publication
First Author: Liu Y
Year: 2019
Journal: Nat Commun
Title: SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice.
Volume: 10
Issue: 1
Pages: 1886
Publication  
First Author: Koentges C
Year: 2019
Journal: J Mol Cell Cardiol
Title: Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
Volume: 133
Pages: 138-147
Publication
First Author: Sundaresan NR
Year: 2009
Journal: J Clin Invest
Title: Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice.
Volume: 119
Issue: 9
Pages: 2758-71
Publication
First Author: Palacios OM
Year: 2009
Journal: Aging (Albany NY)
Title: Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle.
Volume: 1
Issue: 9
Pages: 771-83
Publication
First Author: Srivastava SP
Year: 2018
Journal: Cell Death Dis
Title: SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis.
Volume: 9
Issue: 10
Pages: 997
Publication
First Author: Sundaresan NR
Year: 2015
Journal: Mol Cell Biol
Title: SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.
Volume: 36
Issue: 5
Pages: 678-92
Publication  
First Author: Mukherjee S
Year: 2021
Journal: JCI Insight
Title: SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside.
Volume: 6
Issue: 7
Publication  
First Author: Martin AS
Year: 2017
Journal: JCI Insight
Title: Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model.
Volume: 2
Issue: 14
Publication
First Author: Zhao J
Year: 2022
Journal: Cell Death Dis
Title: Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
Volume: 13
Issue: 7
Pages: 594
Publication
First Author: Dikalova AE
Year: 2020
Journal: Circ Res
Title: Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Volume: 126
Issue: 4
Pages: 439-452
Publication
First Author: Patel S
Year: 2020
Journal: PLoS One
Title: SIRT3 promotes auditory function in young adult FVB/nJ mice but is dispensable for hearing recovery after noise exposure.
Volume: 15
Issue: 7
Pages: e0235491
Publication  
First Author: Qian K
Year: 2023
Journal: EBioMedicine
Title: Exogenous NADPH exerts a positive inotropic effect and enhances energy metabolism via SIRT3 in pathological cardiac hypertrophy and heart failure.
Volume: 98
Pages: 104863
Publication
First Author: Wei (魏彤) T
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function.
Volume: 41
Issue: 2
Pages: 714-730
Publication
First Author: Yang S
Year: 2020
Journal: J Cell Mol Med
Title: SIRT3 deficiency delays diabetic skin wound healing via oxidative stress and necroptosis enhancement.
Volume: 24
Issue: 8
Pages: 4415-4427
Publication
First Author: Chhabra G
Year: 2022
Journal: J Invest Dermatol
Title: Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in Braf(V600E)/Pten(NULL) Mice.
Volume: 142
Issue: 4
Pages: 1145-1157.e7
Publication
First Author: Zhang Y
Year: 2015
Journal: PLoS One
Title: SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.
Volume: 10
Issue: 3
Pages: e0122297
Publication
First Author: Wang S
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Mst1 inhibits Sirt3 expression and contributes to diabetic cardiomyopathy through inhibiting Parkin-dependent mitophagy.
Volume: 1865
Issue: 7
Pages: 1905-1914
Publication
First Author: Kawamura Y
Year: 2010
Journal: J Clin Invest
Title: Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.
Volume: 120
Issue: 8
Pages: 2817-28
Publication
First Author: Lantier L
Year: 2015
Journal: Diabetes
Title: SIRT3 Is Crucial for Maintaining Skeletal Muscle Insulin Action and Protects Against Severe Insulin Resistance in High-Fat-Fed Mice.
Volume: 64
Issue: 9
Pages: 3081-92
Publication  
First Author: Heinonen T
Year: 2019
Journal: Front Immunol
Title: Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia.
Volume: 10
Pages: 2713
Publication
First Author: Sundaresan NR
Year: 2008
Journal: Mol Cell Biol
Title: SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Volume: 28
Issue: 20
Pages: 6384-401