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Search results 1 to 100 out of 125 for Sirt4

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0.04s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Anderson KA
Year: 2017
Journal: Cell Metab
Title: SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Volume: 25
Issue: 4
Pages: 838-855.e15
Publication
First Author: Shih J
Year: 2014
Journal: J Neurochem
Title: Loss of SIRT4 decreases GLT-1-dependent glutamate uptake and increases sensitivity to kainic acid.
Volume: 131
Issue: 5
Pages: 573-81
Publication  
First Author: Shaw E
Year: 2020
Journal: Mol Cell Biol
Title: Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria.
Volume: 40
Issue: 2
Publication
First Author: Luo YX
Year: 2017
Journal: Eur Heart J
Title: SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity.
Volume: 38
Issue: 18
Pages: 1389-1398
Publication
First Author: Jeong SM
Year: 2013
Journal: Cancer Cell
Title: SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism.
Volume: 23
Issue: 4
Pages: 450-63
Publication
First Author: Laurent G
Year: 2013
Journal: Mol Cell
Title: SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.
Volume: 50
Issue: 5
Pages: 686-98
Publication
First Author: Laurent G
Year: 2013
Journal: Mol Cell Biol
Title: SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation.
Volume: 33
Issue: 22
Pages: 4552-61
Publication
First Author: Haigis MC
Year: 2006
Journal: Cell
Title: SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.
Volume: 126
Issue: 5
Pages: 941-54
Publication
First Author: Jeong SM
Year: 2014
Journal: J Biol Chem
Title: SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.
Volume: 289
Issue: 7
Pages: 4135-44
HT Experiment
Series Id: GSE56321
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Mathias RA
Year: 2014
Journal: Cell
Title: Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.
Volume: 159
Issue: 7
Pages: 1615-25
Publication
First Author: Mahlknecht U
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Fluorescence in situ hybridization and chromosomal organization of the sirtuin 4 gene (Sirt4) in the mouse.
Volume: 382
Issue: 4
Pages: 685-90
Publication
First Author: Xiao Y
Year: 2016
Journal: PLoS One
Title: MicroRNA-497 Inhibits Cardiac Hypertrophy by Targeting Sirt4.
Volume: 11
Issue: 12
Pages: e0168078
Publication
First Author: Lin W
Year: 2019
Journal: Immunology
Title: Sirtuin4 suppresses the anti-neuroinflammatory activity of infiltrating regulatory T cells in the traumatically injured spinal cord.
Volume: 158
Issue: 4
Pages: 362-374
Publication
First Author: Huynh FK
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice.
Volume: 319
Issue: 4
Pages: E805-E813
Publication
First Author: Huynh FK
Year: 2018
Journal: J Inherit Metab Dis
Title: Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds.
Volume: 41
Issue: 1
Pages: 59-72
Publication
First Author: Wang YS
Year: 2019
Journal: Hepatology
Title: Sirtuin 4 Depletion Promotes Hepatocellular Carcinoma Tumorigenesis Through Regulating Adenosine-Monophosphate-Activated Protein Kinase Alpha/Mammalian Target of Rapamycin Axis in Mice.
Volume: 69
Issue: 4
Pages: 1614-1631
Publication
First Author: Csibi A
Year: 2013
Journal: Cell
Title: The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Volume: 153
Issue: 4
Pages: 840-54
Publication
First Author: Lombard DB
Year: 2007
Journal: Mol Cell Biol
Title: Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Volume: 27
Issue: 24
Pages: 8807-14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:4833807
Age: embryonic day 1.0
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:4833816
Age: embryonic day 1.0
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:4833807
Age: embryonic day 3.0
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:4833816
Age: embryonic day 3.0
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:4833807
Age: embryonic day 0.5
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4833807
Age: embryonic day 3.5
Image: 1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4833816
Age: embryonic day 3.5
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360633
Stage: TS03
Assay Id: MGI:4833807
Age: embryonic day 2.0
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4833807
Age: postnatal
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4833787
Assay Type: RT-PCR
Annotation Date: 2010-10-05
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4833816
Age: postnatal
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311755
Note: kidney
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311758
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311760
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311752
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311760
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311750
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311760
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311757
Detected: true
Specimen Num: 5
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311757
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311752
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311751
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311758
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311759
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311753
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311754
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311756
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692118
Age: postnatal adult
Image: MRC Harwell_1311760
Detected: true
Specimen Num: 8
Publication    
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, clone IMAGE: 4219186, mRNA, partial cds
Pages: BC022653
Publication
First Author: Nakamura Y
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5.
Volume: 366
Issue: 1
Pages: 174-9
Publication
First Author: Nakagawa T
Year: 2009
Journal: Cell
Title: SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle.
Volume: 137
Issue: 3
Pages: 560-70
Publication
First Author: Kawamura Y
Year: 2010
Journal: J Clin Invest
Title: Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.
Volume: 120
Issue: 8
Pages: 2817-28
Publication
First Author: Martin J
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein.
Volume: 310
Issue: 7
Pages: G497-509
Publication
First Author: Witt O
Year: 2009
Journal: Cancer Lett
Title: HDAC family: What are the cancer relevant targets?
Volume: 277
Issue: 1
Pages: 8-21
Publication
First Author: Poché RA
Year: 2016
Journal: Cell Rep
Title: RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina.
Volume: 14
Issue: 7
Pages: 1684-1697
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9