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Search results 1 to 100 out of 368 for Sirt6

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0.041s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Chen L
Year: 2019
Journal: J Biol Chem
Title: Hepatocyte-specific Sirt6 deficiency impairs ketogenesis.
Volume: 294
Issue: 5
Pages: 1579-1589
Publication
First Author: Okun E
Year: 2017
Journal: PLoS One
Title: Sirt6 alters adult hippocampal neurogenesis.
Volume: 12
Issue: 6
Pages: e0179681
Publication
First Author: Silberman DM
Year: 2014
Journal: PLoS One
Title: SIRT6 is required for normal retinal function.
Volume: 9
Issue: 6
Pages: e98831
Publication
First Author: Wei H
Year: 2020
Journal: Aging (Albany NY)
Title: Sirt6 is required for spermatogenesis in mice.
Volume: 12
Issue: 17
Pages: 17099-17113
Publication  
First Author: Sugatani T
Year: 2015
Journal: Bone
Title: SIRT6 deficiency culminates in low-turnover osteopenia.
Volume: 81
Pages: 168-77
Publication
First Author: Kaidi A
Year: 2010
Journal: Science
Title: Human SIRT6 promotes DNA end resection through CtIP deacetylation.
Volume: 329
Issue: 5997
Pages: 1348-53
Publication
First Author: Mao Z
Year: 2011
Journal: Science
Title: SIRT6 promotes DNA repair under stress by activating PARP1.
Volume: 332
Issue: 6036
Pages: 1443-6
Publication
First Author: Kanfi Y
Year: 2012
Journal: Nature
Title: The sirtuin SIRT6 regulates lifespan in male mice.
Volume: 483
Issue: 7388
Pages: 218-21
Publication
First Author: Zhong L
Year: 2010
Journal: Cell
Title: The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.
Volume: 140
Issue: 2
Pages: 280-93
Publication
First Author: Naiman S
Year: 2019
Journal: Cell Rep
Title: SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.
Volume: 29
Issue: 12
Pages: 4127-4143.e8
Publication
First Author: Yao L
Year: 2017
Journal: Cell Rep
Title: Cold-Inducible SIRT6 Regulates Thermogenesis of Brown and Beige Fat.
Volume: 20
Issue: 3
Pages: 641-654
Publication
First Author: Etchegaray JP
Year: 2019
Journal: Mol Cell
Title: The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
Volume: 75
Issue: 4
Pages: 683-699.e7
Publication  
First Author: Xu K
Year: 2020
Journal: Cells
Title: Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in Mice.
Volume: 9
Issue: 6
Publication
First Author: Sun S
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Sirt6 deacetylase activity regulates circadian rhythms via Per2.
Volume: 511
Issue: 2
Pages: 234-238
Publication
First Author: Kugel S
Year: 2016
Journal: Cell
Title: SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Volume: 165
Issue: 6
Pages: 1401-1415
Publication
First Author: Liszt G
Year: 2005
Journal: J Biol Chem
Title: Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase.
Volume: 280
Issue: 22
Pages: 21313-20
Publication
First Author: Zhang D
Year: 2018
Journal: Sci Rep
Title: Evidence for excessive osteoclast activation in SIRT6 null mice.
Volume: 8
Issue: 1
Pages: 10992
Publication
First Author: Kanfi Y
Year: 2010
Journal: Aging Cell
Title: SIRT6 protects against pathological damage caused by diet-induced obesity.
Volume: 9
Issue: 2
Pages: 162-73
Publication  
First Author: Park SJ
Year: 2016
Journal: Sci Rep
Title: Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation.
Volume: 6
Pages: 26186
Publication
First Author: Ronnebaum SM
Year: 2013
Journal: Mol Cell Biol
Title: The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination.
Volume: 33
Issue: 22
Pages: 4461-72
Publication  
First Author: Hao L
Year: 2020
Journal: JCI Insight
Title: ERRγ suppression by Sirt6 alleviates cholestatic liver injury and fibrosis.
Volume: 5
Issue: 17
Publication
First Author: Ming M
Year: 2014
Journal: Cancer Res
Title: SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer.
Volume: 74
Issue: 20
Pages: 5925-33
Publication
First Author: Chen W
Year: 2017
Journal: Cell Rep
Title: Sirt6 Promotes DNA End Joining in iPSCs Derived from Old Mice.
Volume: 18
Issue: 12
Pages: 2880-2892
Publication
First Author: Zhang P
Year: 2017
Journal: Sci Rep
Title: SIRT6 promotes osteogenic differentiation of mesenchymal stem cells through BMP signaling.
Volume: 7
Issue: 1
Pages: 10229
Publication  
First Author: Tang Q
Year: 2020
Journal: Mol Metab
Title: Sirt6 in pro-opiomelanocortin neurons controls energy metabolism by modulating leptin signaling.
Volume: 37
Pages: 100994
Publication  
First Author: Piao J
Year: 2013
Journal: Sci Rep
Title: Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling.
Volume: 3
Pages: 3022
Publication
First Author: Chen Q
Year: 2017
Journal: Cell Rep
Title: SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion.
Volume: 18
Issue: 13
Pages: 3155-3166
Publication
First Author: Sebastián C
Year: 2012
Journal: Cell
Title: The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Volume: 151
Issue: 6
Pages: 1185-99
Publication
First Author: Masri S
Year: 2014
Journal: Cell
Title: Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.
Volume: 158
Issue: 3
Pages: 659-72
Publication
First Author: Liao X
Year: 2017
Journal: PLoS One
Title: The Sirt6 gene: Does it play a role in tooth development?
Volume: 12
Issue: 3
Pages: e0174255
Publication
First Author: Dominy JE Jr
Year: 2012
Journal: Mol Cell
Title: The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.
Volume: 48
Issue: 6
Pages: 900-13
Publication
First Author: Ailixiding M
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis.
Volume: 466
Issue: 3
Pages: 319-26
Publication
First Author: Toiber D
Year: 2013
Journal: Mol Cell
Title: SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.
Volume: 51
Issue: 4
Pages: 454-68
Publication
First Author: Jedrusik-Bode M
Year: 2013
Journal: J Cell Sci
Title: The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals.
Volume: 126
Issue: Pt 22
Pages: 5166-77
Publication
First Author: Wang H
Year: 2016
Journal: Cell Stem Cell
Title: SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling.
Volume: 18
Issue: 4
Pages: 495-507
Publication
First Author: Samant SA
Year: 2017
Journal: Sci Rep
Title: The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.
Volume: 7
Issue: 1
Pages: 11877
Publication
First Author: Sociali G
Year: 2019
Journal: FASEB J
Title: SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Volume: 33
Issue: 3
Pages: 3704-3717
Publication
First Author: Jiang H
Year: 2013
Journal: Nature
Title: SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine.
Volume: 496
Issue: 7443
Pages: 110-3
Publication
First Author: Liu M
Year: 2017
Journal: Nat Commun
Title: Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Volume: 8
Issue: 1
Pages: 413
Publication
First Author: Kuang J
Year: 2017
Journal: Diabetes
Title: Fat-Specific Sirt6 Ablation Sensitizes Mice to High-Fat Diet-Induced Obesity and Insulin Resistance by Inhibiting Lipolysis.
Volume: 66
Issue: 5
Pages: 1159-1171
Publication
First Author: Cui X
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: SIRT6 regulates metabolic homeostasis in skeletal muscle through activation of AMPK.
Volume: 313
Issue: 4
Pages: E493-E505
Publication
First Author: Kawahara TL
Year: 2009
Journal: Cell
Title: SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span.
Volume: 136
Issue: 1
Pages: 62-74
Publication
First Author: Zhang P
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.
Volume: 111
Issue: 29
Pages: 10684-9
Publication
First Author: Guo J
Year: 2019
Journal: Circ Res
Title: Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling.
Volume: 124
Issue: 10
Pages: 1448-1461
Publication
First Author: Xiao C
Year: 2010
Journal: J Biol Chem
Title: SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulin-stimulated glucose uptake in mice.
Volume: 285
Issue: 47
Pages: 36776-84
Publication
First Author: Tang C
Year: 2019
Journal: J Cell Physiol
Title: Sirt6 deletion in hepatocytes increases insulin sensitivity of female mice by enhancing ERα expression.
Volume: 234
Issue: 10
Pages: 18615-18625
Publication
First Author: Ravi V
Year: 2019
Journal: Nucleic Acids Res
Title: SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity.
Volume: 47
Issue: 17
Pages: 9115-9131
Publication  
First Author: Arsiwala T
Year: 2020
Journal: J Mol Cell Cardiol
Title: Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
Volume: 139
Pages: 24-32
Publication
First Author: Bauer I
Year: 2012
Journal: J Biol Chem
Title: The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.
Volume: 287
Issue: 49
Pages: 40924-37
Publication  
First Author: Song MY
Year: 2016
Journal: Sci Rep
Title: Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway.
Volume: 6
Pages: 30321
Publication
First Author: Li Z
Year: 2020
Journal: Aging Cell
Title: A high-fat diet reverses metabolic disorders and premature aging by modulating insulin and IGF1 signaling in SIRT6 knockout mice.
Volume: 19
Issue: 3
Pages: e13104
Publication
First Author: Kim HS
Year: 2010
Journal: Cell Metab
Title: Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.
Volume: 12
Issue: 3
Pages: 224-36
Publication
First Author: Kim HG
Year: 2019
Journal: J Hepatol
Title: The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice.
Volume: 71
Issue: 5
Pages: 960-969
Publication
First Author: Xiao C
Year: 2012
Journal: J Biol Chem
Title: Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice.
Volume: 287
Issue: 50
Pages: 41903-13
Publication
First Author: Van Meter M
Year: 2016
Journal: Cell Rep
Title: JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks.
Volume: 16
Issue: 10
Pages: 2641-2650
Publication
First Author: Tao R
Year: 2013
Journal: J Biol Chem
Title: FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression.
Volume: 288
Issue: 41
Pages: 29252-9
Publication
First Author: Xiong X
Year: 2017
Journal: J Endocrinol
Title: Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice.
Volume: 233
Issue: 3
Pages: 307-314
Publication
First Author: Anderson JG
Year: 2015
Journal: Mol Metab
Title: Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6.
Volume: 4
Issue: 11
Pages: 846-56
Publication
First Author: Mostoslavsky R
Year: 2006
Journal: Cell
Title: Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.
Volume: 124
Issue: 2
Pages: 315-29
Publication
First Author: Peshti V
Year: 2017
Journal: PLoS One
Title: Characterization of physiological defects in adult SIRT6-/- mice.
Volume: 12
Issue: 4
Pages: e0176371
Publication
First Author: Simon M
Year: 2019
Journal: Cell Metab
Title: LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Volume: 29
Issue: 4
Pages: 871-885.e5
Publication
First Author: Kaluski S
Year: 2017
Journal: Cell Rep
Title: Neuroprotective Functions for the Histone Deacetylase SIRT6.
Volume: 18
Issue: 13
Pages: 3052-3062
Publication
First Author: Elhanati S
Year: 2013
Journal: Cell Rep
Title: Multiple regulatory layers of SREBP1/2 by SIRT6.
Volume: 4
Issue: 5
Pages: 905-12
Publication
First Author: Maity S
Year: 2020
Journal: J Biol Chem
Title: Sirtuin 6 deficiency transcriptionally up-regulates TGF-β signaling and induces fibrosis in mice.
Volume: 295
Issue: 2
Pages: 415-434
Publication  
First Author: Kim SJ
Year: 2020
Journal: Bone
Title: Loss of Sirtuin 6 in osteoblast lineage cells activates osteoclasts, resulting in osteopenia.
Volume: 138
Pages: 115497
Publication
First Author: Xiong X
Year: 2016
Journal: Diabetologia
Title: Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells.
Volume: 59
Issue: 1
Pages: 151-60
Publication
First Author: Ka SO
Year: 2017
Journal: FASEB J
Title: Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor.
Volume: 31
Issue: 9
Pages: 3999-4010
Publication
First Author: Schwer B
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.
Volume: 107
Issue: 50
Pages: 21790-4
Publication
First Author: Lee Y
Year: 2017
Journal: Diabetes
Title: Myeloid Sirtuin 6 Deficiency Causes Insulin Resistance in High-Fat Diet-Fed Mice by Eliciting Macrophage Polarization Toward an M1 Phenotype.
Volume: 66
Issue: 10
Pages: 2659-2668
Publication  
First Author: Woo SJ
Year: 2018
Journal: EBioMedicine
Title: Myeloid sirtuin 6 deficiency accelerates experimental rheumatoid arthritis by enhancing macrophage activation and infiltration into synovium.
Volume: 38
Pages: 228-237
Publication  
First Author: Xin Y
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Volume: 544
Pages: 44-51
Publication
First Author: Santos-Barriopedro I
Year: 2018
Journal: Nat Commun
Title: SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Volume: 9
Issue: 1
Pages: 101
Publication    
First Author: Ghosh S
Year: 2018
Journal: Elife
Title: Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice.
Volume: 7
Publication
First Author: Zorrilla-Zubilete MA
Year: 2018
Journal: J Neurochem
Title: Epigenetic control of early neurodegenerative events in diabetic retinopathy by the histone deacetylase SIRT6.
Volume: 144
Issue: 2
Pages: 128-138
Publication    
First Author: Qian M
Year: 2018
Journal: Elife
Title: Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.
Volume: 7
Publication
First Author: Min L
Year: 2012
Journal: Nat Cell Biol
Title: Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.
Volume: 14
Issue: 11
Pages: 1203-11
Publication
First Author: Bang IH
Year: 2019
Journal: Exp Mol Med
Title: Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis.
Volume: 51
Issue: 9
Pages: 1-11
Publication
First Author: Favero G
Year: 2014
Journal: Acta Histochem
Title: Sirtuin 6 nuclear localization at cortical brain level of young diabetic mice: an immunohistochemical study.
Volume: 116
Issue: 1
Pages: 272-7
Publication  
First Author: Zhang W
Year: 2017
Journal: Neuroscience
Title: Sirtuin 6 protects the brain from cerebral ischemia/reperfusion injury through NRF2 activation.
Volume: 366
Pages: 95-104
Publication
First Author: Song MY
Year: 2019
Journal: Exp Mol Med
Title: Adipose sirtuin 6 drives macrophage polarization toward M2 through IL-4 production and maintains systemic insulin sensitivity in mice and humans.
Volume: 51
Issue: 5
Pages: 1-10
Publication
First Author: Qin K
Year: 2018
Journal: Diabetologia
Title: SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Volume: 61
Issue: 4
Pages: 906-918
Publication
First Author: Tao R
Year: 2013
Journal: J Lipid Res
Title: Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6.
Volume: 54
Issue: 10
Pages: 2745-53
Publication
First Author: Jung SM
Year: 2019
Journal: Mol Cell
Title: Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Volume: 75
Issue: 4
Pages: 807-822.e8
Publication
First Author: Zhang L
Year: 2016
Journal: J Clin Invest
Title: Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration.
Volume: 126
Issue: 12
Pages: 4659-4673
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus