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Search results 1 to 78 out of 78 for Slc10a1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Solute carrier family 10 member 1 (SLC10A1), also known as sodium/taurocholate cotransporting polypeptide (NTCP), represents a hepatic sodium/bile acid uptake system that exhibits broad substrate specificity []. NTCP also transports various non-bile acid organic compounds, including steroidal hormones such as estrone-3-sulfate and dehydroepiandrosterone (DHEAS), bromosulphthalein and a variety of xenobiotics []. It also mediates transport of (sulfated) iodothyronines [].
Publication
First Author: Hagenbuch B
Year: 1994
Journal: J Clin Invest
Title: Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.
Volume: 93
Issue: 3
Pages: 1326-31
Publication
First Author: Kersseboom S
Year: 2017
Journal: Endocrinology
Title: Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome.
Volume: 158
Issue: 10
Pages: 3307-3318
Protein
Organism: Mus musculus
Length: 362  
Fragment?: false
Protein
Organism: Mus musculus
Length: 111  
Fragment?: true
Protein
Organism: Mus musculus
Length: 66  
Fragment?: false
Protein
Organism: Mus musculus
Length: 317  
Fragment?: false
Publication  
First Author: Stieger B
Year: 2011
Journal: Handb Exp Pharmacol
Title: The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.
Issue: 201
Pages: 205-59
Publication
First Author: Visser WE
Year: 2010
Journal: Mol Cell Endocrinol
Title: Study of the transport of thyroid hormone by transporters of the SLC10 family.
Volume: 315
Issue: 1-2
Pages: 138-45
Publication
First Author: Mao F
Year: 2019
Journal: J Biol Chem
Title: Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency.
Volume: 294
Issue: 31
Pages: 11853-11862
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hagenbuch B
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.
Volume: 88
Issue: 23
Pages: 10629-33
Publication
First Author: Slijepcevic D
Year: 2015
Journal: Hepatology
Title: Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.
Volume: 62
Issue: 1
Pages: 207-19
Publication
First Author: Torchia EC
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Coordinate regulation of bile acid biosynthetic and recovery pathways.
Volume: 225
Issue: 1
Pages: 128-33
Publication
First Author: Green RM
Year: 1998
Journal: Mamm Genome
Title: Genetic mapping of the Na(+)-taurocholate cotransporting polypeptide to mouse chromosome 12.
Volume: 9
Issue: 7
Pages: 598
Publication
First Author: Cattori V
Year: 1999
Journal: Biochim Biophys Acta
Title: Molecular cloning and functional characterization of two alternatively spliced Ntcp isoforms from mouse liver1.
Volume: 1445
Issue: 1
Pages: 154-9
Publication
First Author: Hallén S
Year: 2002
Journal: Biochemistry
Title: Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor.
Volume: 41
Issue: 50
Pages: 14916-24
Publication
First Author: Molina H
Year: 2008
Journal: Biochim Biophys Acta
Title: Localization of the Sodium-Taurocholate cotransporting polypeptide in membrane rafts and modulation of its activity by cholesterol in vitro.
Volume: 1778
Issue: 5
Pages: 1283-91
GXD Expression    
Probe: MGI:4427258
Assay Type: RNA in situ
Annotation Date: 2011-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4888548
Age: embryonic day 14.5
Image: Table S1
Detected: false
Specimen Num: 1
Publication
First Author: Koopen NR
Year: 1999
Journal: J Hepatol
Title: Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice.
Volume: 30
Issue: 1
Pages: 14-21
Publication    
First Author: Donkers JM
Year: 2019
Journal: JCI Insight
Title: NTCP deficiency in mice protects against obesity and hepatosteatosis.
Volume: 5
Publication
First Author: Zollner G
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Volume: 289
Issue: 5
Pages: G798-805
Publication
First Author: Geier A
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene.
Volume: 295
Issue: 2
Pages: G226-33
Publication
First Author: Slijepcevic D
Year: 2017
Journal: Hepatology
Title: Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
Volume: 66
Issue: 5
Pages: 1631-1643
Publication
First Author: Festing MH
Year: 2009
Journal: Genesis
Title: Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.
Volume: 47
Issue: 12
Pages: 858-63
Publication
First Author: Abe K
Year: 2015
Journal: EMBO J
Title: The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing.
Volume: 34
Issue: 11
Pages: 1523-37
Publication
First Author: Shih DQ
Year: 2001
Journal: Nat Genet
Title: Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.
Volume: 27
Issue: 4
Pages: 375-82
Publication
First Author: Cheng X
Year: 2008
Journal: Toxicol Sci
Title: Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.
Volume: 106
Issue: 1
Pages: 37-45
Publication
First Author: Cui JY
Year: 2012
Journal: Toxicol Sci
Title: RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.
Volume: 127
Issue: 2
Pages: 592-608
Publication
First Author: Ferrell JM
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Volume: 57
Issue: 7
Pages: 1144-54
Publication
First Author: Briançon N
Year: 2006
Journal: EMBO J
Title: In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.
Volume: 25
Issue: 6
Pages: 1253-62
Publication
First Author: Lammert F
Year: 2001
Journal: Gastroenterology
Title: Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.
Volume: 120
Issue: 1
Pages: 221-38
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Allele
Name: transgene insertion 15, Micheal Wiles
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication categories: ProxyCollection
Allele
Name: transgene insertion 39, Micheal Wiles
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication categories: ProxyCollection
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication  
First Author: Winer BY
Year: 2018
Journal: Sci Transl Med
Title: Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.
Volume: 10
Issue: 447
Strain
Attribute String: transgenic, mutant strain, congenic, targeted mutation