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Search results 1 to 100 out of 495 for Slc12a2

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0.036s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Ando Z
Year: 2005
Journal: FEBS J
Title: Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4.
Volume: 272
Issue: 12
Pages: 3026-41
Publication
First Author: Dixon MJ
Year: 1999
Journal: Hum Mol Genet
Title: Mutation of the Na-K-Cl co-transporter gene Slc12a2 results in deafness in mice.
Volume: 8
Issue: 8
Pages: 1579-84
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191310
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Slc12a2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191310
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Slc12a2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191310
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Slc12a2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191310
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Slc12a2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191310
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Slc12a2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191310
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Slc12a2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6183379
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191310
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Slc12a2
Detected: true
Specimen Num: 7
Publication
First Author: Perry JSA
Year: 2019
Journal: Nat Cell Biol
Title: Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Volume: 21
Issue: 12
Pages: 1532-1543
Publication
First Author: Alshahrani S
Year: 2012
Journal: J Endocrinol
Title: Enhanced insulin secretion and improved glucose tolerance in mice with homozygous inactivation of the Na(+)K(+)2Cl(-) co-transporter 1.
Volume: 215
Issue: 1
Pages: 59-70
Publication
First Author: Bradford EM
Year: 2016
Journal: World J Gastrointest Pathophysiol
Title: Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine.
Volume: 7
Issue: 1
Pages: 138-49
Publication
First Author: Randall J
Year: 1997
Journal: Am J Physiol
Title: Partial cloning and characterization of Slc12a2: the gene encoding the secretory Na+-K+-2Cl- cotransporter.
Volume: 273
Issue: 4 Pt 1
Pages: C1267-77
Publication
First Author: Koumangoye R
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation.
Volume: 9
Issue: 2
Pages: 239-255
Publication    
First Author: Köchl R
Year: 2020
Journal: Elife
Title: Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
Volume: 9
Publication
First Author: Zhu MH
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Na+-K+-Cl- cotransporter (NKCC) maintains the chloride gradient to sustain pacemaker activity in interstitial cells of Cajal.
Volume: 311
Issue: 6
Pages: G1037-G1046
Publication
First Author: Pace AJ
Year: 2000
Journal: J Clin Invest
Title: Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter.
Volume: 105
Issue: 4
Pages: 441-50
Publication
First Author: Vanden Heuvel GB
Year: 2006
Journal: Gene Expr Patterns
Title: Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development.
Volume: 6
Issue: 8
Pages: 1000-6
Publication
First Author: Delpire E
Year: 1999
Journal: Nat Genet
Title: Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
Volume: 22
Issue: 2
Pages: 192-5
Publication
First Author: Antoine MW
Year: 2017
Journal: J Neurosci
Title: The Severity of Vestibular Dysfunction in Deafness as a Determinant of Comorbid Hyperactivity or Anxiety.
Volume: 37
Issue: 20
Pages: 5144-5154
Publication
First Author: Li X
Year: 2013
Journal: PLoS One
Title: Endolymphatic Na⁺ and K⁺ concentrations during cochlear growth and enlargement in mice lacking Slc26a4/pendrin.
Volume: 8
Issue: 5
Pages: e65977
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Delpire E
Year: 1994
Journal: J Biol Chem
Title: Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells.
Volume: 269
Issue: 41
Pages: 25677-83
Publication
First Author: Watabe T
Year: 2017
Journal: Sci Rep
Title: Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice.
Volume: 7
Issue: 1
Pages: 13605
Publication
First Author: Yamazaki Y
Year: 2021
Journal: Nat Commun
Title: Oligodendrocytic Na(+)-K(+)-Cl(-) co-transporter 1 activity facilitates axonal conduction and restores plasticity in the adult mouse brain.
Volume: 12
Issue: 1
Pages: 5146
Publication
First Author: Zhang LL
Year: 2007
Journal: J Neurophysiol
Title: NKCC1 does not accumulate chloride in developing retinal neurons.
Volume: 98
Issue: 1
Pages: 266-77
Publication
First Author: Grubb BR
Year: 2000
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Intestinal ion transport in NKCC1-deficient mice.
Volume: 279
Issue: 4
Pages: G707-18
Publication
First Author: Grubb BR
Year: 2001
Journal: Am J Physiol Cell Physiol
Title: Alterations in airway ion transport in NKCC1-deficient mice.
Volume: 281
Issue: 2
Pages: C615-23
Publication
First Author: Nguyen M
Year: 2007
Journal: J Exp Med
Title: Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Volume: 204
Issue: 6
Pages: 1383-93
Publication
First Author: Khirug S
Year: 2008
Journal: J Neurosci
Title: GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1.
Volume: 28
Issue: 18
Pages: 4635-9
Publication
First Author: Pace AJ
Year: 2001
Journal: Hear Res
Title: Ultrastructure of the inner ear of NKCC1-deficient mice.
Volume: 156
Issue: 1-2
Pages: 17-30
Publication
First Author: Koumangoye R
Year: 2018
Journal: Am J Physiol Cell Physiol
Title: Mistargeting of a truncated Na-K-2Cl cotransporter in epithelial cells.
Volume: 315
Issue: 2
Pages: C258-C276
Publication
First Author: Koumangoye R
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: A dileucine motif in the COOH-terminal domain of NKCC1 targets the cotransporter to the plasma membrane.
Volume: 316
Issue: 4
Pages: C545-C558
Publication
First Author: Ge S
Year: 2006
Journal: Nature
Title: GABA regulates synaptic integration of newly generated neurons in the adult brain.
Volume: 439
Issue: 7076
Pages: 589-93
Publication
First Author: Laird JM
Year: 2004
Journal: Neurosci Lett
Title: Presynaptic inhibition and spinal pain processing in mice: a possible role of the NKCC1 cation-chloride co-transporter in hyperalgesia.
Volume: 361
Issue: 1-3
Pages: 200-3
Publication
First Author: Gregoriades JMC
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Genetic and pharmacological inactivation of apical Na+-K+-2Cl- cotransporter 1 in choroid plexus epithelial cells reveals the physiological function of the cotransporter.
Volume: 316
Issue: 4
Pages: C525-C544
Publication
First Author: Dzhala VI
Year: 2005
Journal: Nat Med
Title: NKCC1 transporter facilitates seizures in the developing brain.
Volume: 11
Issue: 11
Pages: 1205-13
Publication
First Author: Sung KW
Year: 2000
Journal: J Neurosci
Title: Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
Volume: 20
Issue: 20
Pages: 7531-8
Publication
First Author: Reisert J
Year: 2005
Journal: Neuron
Title: Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons.
Volume: 45
Issue: 4
Pages: 553-61
Publication
First Author: Flagella M
Year: 1999
Journal: J Biol Chem
Title: Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.
Volume: 274
Issue: 38
Pages: 26946-55
Publication
First Author: Kim SM
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Salt sensitivity of blood pressure in NKCC1-deficient mice.
Volume: 295
Issue: 4
Pages: F1230-8
Publication
First Author: Evans RL
Year: 2000
Journal: J Biol Chem
Title: Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.
Volume: 275
Issue: 35
Pages: 26720-6
Publication
First Author: Schöbel N
Year: 2012
Journal: PLoS One
Title: Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses.
Volume: 7
Issue: 11
Pages: e48005
Publication
First Author: Chen H
Year: 2005
Journal: J Cereb Blood Flow Metab
Title: Na(+)-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia.
Volume: 25
Issue: 1
Pages: 54-66
Publication
First Author: Young Choi J
Year: 2005
Journal: Acta Otolaryngol
Title: Vestibular malformation in mice lacking Na-K-2Cl cotransporter 1 and expression of Na-K-2Cl cotransporter 1 in human vestibular end organs.
Volume: 125
Issue: 12
Pages: 1252-7
Publication
First Author: Boyd-Shiwarski CR
Year: 2022
Journal: Cell
Title: WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Volume: 185
Issue: 24
Pages: 4488-4506.e20
Publication
First Author: Demian WL
Year: 2019
Journal: Cell Rep
Title: The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1.
Volume: 27
Issue: 6
Pages: 1886-1896.e6
Publication  
First Author: Hampel P
Year: 2021
Journal: Neurobiol Dis
Title: Deletion of the Na-K-2Cl cotransporter NKCC1 results in a more severe epileptic phenotype in the intrahippocampal kainate mouse model of temporal lobe epilepsy.
Volume: 152
Pages: 105297
Publication
First Author: Meyer JW
Year: 2002
Journal: Am J Physiol Heart Circ Physiol
Title: Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter.
Volume: 283
Issue: 5
Pages: H1846-55
Publication
First Author: Garg P
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone.
Volume: 292
Issue: 5
Pages: H2100-5
Publication
First Author: Castrop H
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Contribution of the basolateral isoform of the Na-K-2Cl- cotransporter (NKCC1/BSC2) to renin secretion.
Volume: 289
Issue: 6
Pages: F1185-92
Publication
First Author: Koltsova SV
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Excitation-contraction coupling in resistance mesenteric arteries: evidence for NKCC1-mediated pathway.
Volume: 379
Issue: 4
Pages: 1080-3
Publication  
First Author: Jalali R
Year: 2017
Journal: Front Physiol
Title: The Role of Na:K:2Cl Cotransporter 1 (NKCC1/SLC12A2) in Dental Epithelium during Enamel Formation in Mice.
Volume: 8
Pages: 924
Publication
First Author: Su G
Year: 2002
Journal: Am J Physiol Cell Physiol
Title: Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release.
Volume: 282
Issue: 5
Pages: C1147-60
Publication
First Author: Haering C
Year: 2015
Journal: J Biol Chem
Title: Ion transporter NKCC1, modulator of neurogenesis in murine olfactory neurons.
Volume: 290
Issue: 15
Pages: 9767-79
Publication
First Author: Sipilä ST
Year: 2009
Journal: J Neurosci
Title: Compensatory enhancement of intrinsic spiking upon NKCC1 disruption in neonatal hippocampus.
Volume: 29
Issue: 21
Pages: 6982-8
Publication
First Author: Wall SM
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Hypotension in NKCC1 null mice: role of the kidneys.
Volume: 290
Issue: 2
Pages: F409-16
Publication  
First Author: Zhang J
Year: 2017
Journal: Neurochem Int
Title: Inhibition of Na+-K+-2Cl- cotransporter attenuates blood-brain-barrier disruption in a mouse model of traumatic brain injury.
Volume: 111
Pages: 23-31
Publication
First Author: Hübner CA
Year: 2001
Journal: Mech Dev
Title: Expression of the Na-K-2Cl-cotransporter NKCC1 during mouse development.
Volume: 102
Issue: 1-2
Pages: 267-9
Publication
First Author: Kaplan MR
Year: 1996
Journal: J Clin Invest
Title: Expression of the mouse Na-K-2Cl cotransporter, mBSC2, in the terminal inner medullary collecting duct, the glomerular and extraglomerular mesangium, and the glomerular afferent arteriole.
Volume: 98
Issue: 3
Pages: 723-30
Publication
First Author: Cutler CP
Year: 2002
Journal: Biochim Biophys Acta
Title: Two isoforms of the Na+/K+/2Cl- cotransporter are expressed in the European eel (Anguilla anguilla).
Volume: 1566
Issue: 1-2
Pages: 92-103
Publication
First Author: Wang DD
Year: 2008
Journal: J Neurosci
Title: GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation.
Volume: 28
Issue: 21
Pages: 5547-58
Publication
First Author: Nickell WT
Year: 2007
Journal: J Physiol
Title: Mechanisms of neuronal chloride accumulation in intact mouse olfactory epithelium.
Volume: 583
Issue: Pt 3
Pages: 1005-20
Publication  
First Author: Mejia-Gervacio S
Year: 2011
Journal: Neural Dev
Title: NKCC1 controls GABAergic signaling and neuroblast migration in the postnatal forebrain.
Volume: 6
Pages: 4
Publication
First Author: Young SZ
Year: 2012
Journal: J Neurosci
Title: NKCC1 knockdown decreases neuron production through GABA(A)-regulated neural progenitor proliferation and delays dendrite development.
Volume: 32
Issue: 39
Pages: 13630-8
GXD Expression      
Probe: MGI:3758194
Assay Type: RT-PCR
Annotation Date: 2007-10-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:3758204
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3758194
Assay Type: RT-PCR
Annotation Date: 2007-10-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:3758204
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5431852
Assay Type: Northern blot
Annotation Date: 2012-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737321
Stage: TS21
Assay Id: MGI:5431910
Age: embryonic day 13.5
Image: 3
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5431852
Assay Type: Northern blot
Annotation Date: 2012-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5431910
Age: embryonic day 14.5
Image: 3
Specimen Label: E14.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5431852
Assay Type: Northern blot
Annotation Date: 2012-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737324
Stage: TS24
Assay Id: MGI:5431910
Age: embryonic day 16.5
Image: 3
Specimen Label: E16.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5431852
Assay Type: Northern blot
Annotation Date: 2012-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:5431910
Age: postnatal day 1
Image: 3
Specimen Label: P1
Detected: true
Specimen Num: 4