| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Solute carrier family 12 member 3 (Slc12a3) is also known as Tsc (thiazide-sensitive Na-Cl co-transporter). Tsc is a large integral membrane protein (~1000 amino acids) that mediates the coupled transport of Na+and Cl-in an electrically silent manner. In the mammalian kidney, it is the dominant mechanism mediating Cl-absorption in the early distal tubule, and here it is the target of the widely-used thiazide class of diuretic drugs. It is also known to be present in the urinary bladder of the winter flounder (Pseudopleuronectes americanus), from where the gene encoding it was initially cloned [].Hydrophobicity analysis predicts the Na-Cl co-transporter to have 12 transmembrane (TM) domains and comparisons with other cloned ion co-transporters reveals that a superfamily of electroneutral cation-chloride co-transporters exists, which includes the K-Cl co-transporters () and the Na-K-Cl co-transporters (). All share a similar predicted membrane topology in a central hydrophobic domain, together with hydrophilic N- and C-termini that are likely cytoplasmic [].Mutations in the thiazide-sensitive Na-Cl co-transporter have been found that give rise to Gitelman's variant of Bartter's syndrome, an inherited kidney disease characterised by hypokalaemic alkalosis []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li Z |
| Year: |
2022 |
| Journal: |
Front Med |
| Title: |
R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
932-945 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1002
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
956
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1002
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1001
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gamba G |
| Year: |
1993 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. |
| Volume: |
90 |
| Issue: |
7 |
| Pages: |
2749-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mount DB |
| Year: |
1998 |
| Journal: |
J Exp Biol |
| Title: |
The electroneutral cation-chloride cotransporters. |
| Volume: |
201 |
| Issue: |
Pt 14 |
| Pages: |
2091-102 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Simon DB |
| Year: |
1996 |
| Journal: |
Nat Genet |
| Title: |
Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
24-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cornelius RJ |
| Year: |
2020 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene. |
| Volume: |
319 |
| Issue: |
3 |
| Pages: |
F423-F435 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maeoka Y |
| Year: |
2024 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Distal convoluted tubule-specific disruption of the COP9 signalosome but not its regulatory target cullin 3 causes tubular injury. |
| Volume: |
327 |
| Issue: |
4 |
| Pages: |
F667-F682 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sabath E |
| Year: |
2004 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease. |
| Volume: |
287 |
| Issue: |
2 |
| Pages: |
F195-203 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Trepiccione F |
| Year: |
2016 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on "single-cell"-specific KO model of the distal nephron. |
| Volume: |
311 |
| Issue: |
5 |
| Pages: |
F901-F906 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mertens RT |
| Year: |
2024 |
| Journal: |
Immunity |
| Title: |
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance. |
| Volume: |
57 |
| Issue: |
9 |
| Pages: |
2077-2094.e12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maga?a-?vila G |
| Year: |
2025 |
| Journal: |
Sci Adv |
| Title: |
NRBP1 and TSC22D proteins affect distal convoluted tubule physiology through modulation of the WNK pathway. |
| Volume: |
11 |
| Issue: |
29 |
| Pages: |
eadv2083 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kunchaparty S |
| Year: |
1999 |
| Journal: |
Am J Physiol |
| Title: |
Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome. |
| Volume: |
277 |
| Issue: |
4 |
| Pages: |
F643-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schultheis PJ |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule. |
| Volume: |
273 |
| Issue: |
44 |
| Pages: |
29150-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morris RG |
| Year: |
2006 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Hypokalemia in a mouse model of Gitelman's syndrome. |
| Volume: |
290 |
| Issue: |
6 |
| Pages: |
F1416-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoorn EJ |
| Year: |
2011 |
| Journal: |
Nat Med |
| Title: |
The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension. |
| Volume: |
17 |
| Issue: |
10 |
| Pages: |
1304-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Loffing J |
| Year: |
2004 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome. |
| Volume: |
15 |
| Issue: |
9 |
| Pages: |
2276-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nicolet-Barousse L |
| Year: |
2005 |
| Journal: |
J Bone Miner Res |
| Title: |
Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice. |
| Volume: |
20 |
| Issue: |
5 |
| Pages: |
799-808 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang C |
| Year: |
2020 |
| Journal: |
Kidney Int |
| Title: |
Low-dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents. |
| Volume: |
98 |
| Issue: |
5 |
| Pages: |
1242-1252 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sinke AP |
| Year: |
2014 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter. |
| Volume: |
306 |
| Issue: |
5 |
| Pages: |
F525-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Needham PG |
| Year: |
2011 |
| Journal: |
J Biol Chem |
| Title: |
The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation. |
| Volume: |
286 |
| Issue: |
51 |
| Pages: |
43611-43621 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu G |
| Year: |
2013 |
| Journal: |
FEBS Lett |
| Title: |
Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation. |
| Volume: |
587 |
| Issue: |
12 |
| Pages: |
1717-22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wild Type |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wild Type |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wild Type |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Het |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Het |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Het |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5473282 |
| Age: |
postnatal |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wild Type |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wild Type |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wild Type |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Het |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Het |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Het |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5475518 |
| Age: |
postnatal |
|
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7645918 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7645930 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Adult Kidney |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7645918 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737320 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:7645930 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
E12.5 Kidney |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7718659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737327 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:7718712 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
Cre- |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7718659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737327 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:7718712 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
Qpc-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7718659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737323 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7718771 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Cre- |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7718659 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737323 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7718771 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Qpc-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5298987 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3516422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422751 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
MH3148; Specimen C4312 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309808 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3516422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423134 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ES391; Specimen S42 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5298987 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716122 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422751 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
MH3148; Specimen C4312 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309808 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716122 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423134 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ES391; Specimen S42 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5298987 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691622 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5422751 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
MH3148; Specimen C4312 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5309808 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691622 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423134 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
ES391; Specimen S42 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
2A top, merge |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
2B top, merge |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
2B bottom, merge |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
6B Wild Type, merge |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
6B KO, merge |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5A Wild Type |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5A Knockout |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5B Wild Type |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5472011 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5B Knockout |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473382 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5473383 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5B WT, merge |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473382 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5473383 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5B KO, merge |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5473386 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5A WT, merge |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473385 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5473386 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5A KO, merge |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473382 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5475519 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5C WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5473382 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5475519 |
| Age: |
postnatal |
|
| Note: |
Expression is the same as in wild type. |
| Specimen Label: |
5C KO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5472007 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2839328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5475520 |
| Age: |
postnatal |
|
|
| Specimen Label: |
5D WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|