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Search results 1 to 100 out of 488 for Slc12a3

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Type Details Score
Gene
6559 | SLC12A3
Type: gene
Organism: human
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Gene
454108 | SLC12A3
Type: gene
Organism: chimpanzee
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Gene
404171 | SLC12A3
Type: gene
Organism: cattle
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Gene
415692 | SLC12A3
Type: gene
Organism: chicken
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Gene
565439 | slc12a3
Type: gene
Organism: zebrafish
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Gene
703090 | SLC12A3
Type: gene
Organism: macaque, rhesus
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Gene
100494755 | slc12a3
Type: gene
Organism: frog, western clawed
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Gene
54300 | Slc12a3
Type: gene
Organism: rat
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Gene
478118 | SLC12A3
Type: gene
Organism: dog, domestic
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Protein Domain
IPR002948 | SLC12A3
Type: Family
Description: Solute carrier family 12 member 3 (Slc12a3) is also known as Tsc (thiazide-sensitive Na-Cl co-transporter). Tsc is a large integral membraneprotein (~1000 amino acids) that mediates the coupled transport of Na+andCl-in an electrically silent manner. In the mammalian kidney, it is thedominant mechanism mediating Cl-absorption in the early distal tubule, andhere it is the target of the widely-used thiazide class of diuretic drugs.It is also known to be present in the urinary bladder of the winterflounder (Pseudopleuronectes americanus), from where the gene encoding it was initially cloned [].Hydrophobicity analysis predicts the Na-Cl co-transporter to have 12transmembrane (TM) domains and comparisons with other cloned ionco-transporters reveals that a superfamily of electroneutral cation-chlorideco-transporters exists, which includes the K-Cl co-transporters ()and the Na-K-Cl co-transporters (). All share a similar predictedmembrane topology in a central hydrophobic domain, together withhydrophilic N- and C-termini that are likely cytoplasmic [].Mutations in the thiazide-sensitive Na-Cl co-transporter have beenfound that give rise to Gitelman's variant of Bartter's syndrome,an inherited kidney disease characterised by hypokalaemic alkalosis [].
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Protein Coding Gene
MGI:108114 | Slc12a3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36370249 | J:336073
First Author: Li Z
Year: 2022
Journal: Front Med
Title: R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.
Volume: 16
Issue: 6
Pages: 932-945
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Protein
P59158
Organism: Mus musculus/domesticus
Length: 1002  
Fragment?: false
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Protein
A0A1D5RLP7
Organism: Mus musculus/domesticus
Length: 956  
Fragment?: false
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Protein
Q543E4
Organism: Mus musculus/domesticus
Length: 1002  
Fragment?: false
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Protein
Q62439
Organism: Mus musculus/domesticus
Length: 1001  
Fragment?: false
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Protein
A0A1D5RLX1
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Publication
8464884 | -
First Author: Gamba G
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter.
Volume: 90
Issue: 7
Pages: 2749-53
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Publication
9639584 | -
First Author: Mount DB
Year: 1998
Journal: J Exp Biol
Title: The electroneutral cation-chloride cotransporters.
Volume: 201
Issue: Pt 14
Pages: 2091-102
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Publication
8528245 | -
First Author: Simon DB
Year: 1996
Journal: Nat Genet
Title: Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter.
Volume: 12
Issue: 1
Pages: 24-30
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Publication
15068971 | J:331463
First Author: Sabath E
Year: 2004
Journal: Am J Physiol Renal Physiol
Title: Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease.
Volume: 287
Issue: 2
Pages: F195-203
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Publication
27582101 | J:281403
First Author: Trepiccione F
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on "single-cell"-specific KO model of the distal nephron.
Volume: 311
Issue: 5
Pages: F901-F906
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Protein Coding Gene
MGP_CAROLIEiJ_G0031396 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_108114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033774 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033721 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032678 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022994 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032515 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10516289 | J:148080
First Author: Kunchaparty S
Year: 1999
Journal: Am J Physiol
Title: Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome.
Volume: 277
Issue: 4 Pt 2
Pages: F643-9
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Publication
23833262 | J:338297
First Author: Yang SS
Year: 2013
Journal: J Am Soc Nephrol
Title: Phosphorylation regulates NCC stability and transporter activity in vivo.
Volume: 24
Issue: 10
Pages: 1587-97
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Publication
9786924 | J:50596
First Author: Schultheis PJ
Year: 1998
Journal: J Biol Chem
Title: Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule.
Volume: 273
Issue: 44
Pages: 29150-5
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Publication
16434571 | J:108639
First Author: Morris RG
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Hypokalemia in a mouse model of Gitelman's syndrome.
Volume: 290
Issue: 6
Pages: F1416-20
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Publication
24352504 | J:207318
First Author: Sinke AP
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter.
Volume: 306
Issue: 5
Pages: F525-33
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Publication
15339977 | J:206786
First Author: Loffing J
Year: 2004
Journal: J Am Soc Nephrol
Title: Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome.
Volume: 15
Issue: 9
Pages: 2276-88
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Publication
21963515 | J:177276
First Author: Hoorn EJ
Year: 2011
Journal: Nat Med
Title: The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.
Volume: 17
Issue: 10
Pages: 1304-9
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Publication
15824853 | J:111256
First Author: Nicolet-Barousse L
Year: 2005
Journal: J Bone Miner Res
Title: Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice.
Volume: 20
Issue: 5
Pages: 799-808
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Publication
29483574 | J:262636
First Author: Pathare G
Year: 2018
Journal: Sci Rep
Title: Elevated FGF23 Levels in Mice Lacking the Thiazide-Sensitive NaCl cotransporter (NCC).
Volume: 8
Issue: 1
Pages: 3590
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Publication
22027832 | J:180688
First Author: Needham PG
Year: 2011
Journal: J Biol Chem
Title: The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation.
Volume: 286
Issue: 51
Pages: 43611-21
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Publication
22718890 | J:188424
First Author: Ko B
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: A new model of the distal convoluted tubule.
Volume: 303
Issue: 5
Pages: F700-10
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Publication
23665031 | J:198926
First Author: Wu G
Year: 2013
Journal: FEBS Lett
Title: Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation.
Volume: 587
Issue: 12
Pages: 1717-22
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: Wild Type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: Wild Type
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: Wild Type
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: Het
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: Het
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: Het
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: KO
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: KO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5472007
Assay Type: Western blot
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5473282
Age: postnatal
Specimen Label: KO
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: Wild Type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: Wild Type
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: Wild Type
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: Het
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: Het
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: Het
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: KO
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: KO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5473385
Assay Type: Western blot
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5475518
Age: postnatal
Specimen Label: KO
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5298987
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422751
Age: embryonic day 14.5
Specimen Label: MH3148; Specimen C4312
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5309808
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5423134
Age: embryonic day 14.5
Specimen Label: ES391; Specimen S42
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5298987
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422751
Age: embryonic day 14.5
Specimen Label: MH3148; Specimen C4312
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5309808
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5423134
Age: embryonic day 14.5
Specimen Label: ES391; Specimen S42
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5298987
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5422751
Age: embryonic day 14.5
Specimen Label: MH3148; Specimen C4312
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5309808
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5423134
Age: embryonic day 14.5
Specimen Label: ES391; Specimen S42
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 2A top, merge
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 2B top, merge
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 2B bottom, merge
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 6B Wild Type, merge
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 6B KO, merge
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 5A Wild Type
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 5A Knockout
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 5B Wild Type
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 5B Knockout
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5473382
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5473383
Age: postnatal
Specimen Label: 5B WT, merge
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5473382
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5473383
Age: postnatal
Specimen Label: 5B KO, merge
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5473385
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5473386
Age: postnatal
Specimen Label: 5A WT, merge
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5473385
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5473386
Age: postnatal
Specimen Label: 5A KO, merge
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5473382
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5475519
Age: postnatal
Specimen Label: 5C WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5473382
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5475519
Age: postnatal
Note: Expression is the same as in wild type.
Specimen Label: 5C KO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5475520
Age: postnatal
Specimen Label: 5D WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5475520
Age: postnatal
Note: Expression is the same as in wild type.
Specimen Label: 5D KO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Specimen Label: 5E Wild Type
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5472007
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472011
Age: postnatal
Note: Expression is present, the mutant has less distal convoluted tubules segments.
Specimen Label: 5E Knockout
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839767
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-12-18
Strength: Present
Sex: Male
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6382078
Age: postnatal adult
Specimen Label: 5A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839767
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-12-18
Strength: Present
Sex: Male
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6382078
Age: postnatal adult
Specimen Label: 5B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839767
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-12-18
Strength: Present
Sex: Male
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6382078
Age: postnatal adult
Specimen Label: 5C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839767
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-12-18
Strength: Present
Sex: Male
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6382078
Age: postnatal adult
Specimen Label: 5D
Detected: true
Specimen Num: 4
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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