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Search results 1 to 100 out of 532 for Slc12a5

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0.048s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: true
Publication
First Author: Puskarjov M
Year: 2014
Journal: EMBO Rep
Title: A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation.
Volume: 15
Issue: 6
Pages: 723-9
Publication
First Author: Sallinen R
Year: 2001
Journal: Cytogenet Cell Genet
Title: Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K(+)-Cl(-) cotransporter (KCC2) defines a new region of conserved homology.
Volume: 94
Issue: 1-2
Pages: 67-70
Publication
First Author: Song L
Year: 2002
Journal: Brain Res Mol Brain Res
Title: Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter.
Volume: 103
Issue: 1-2
Pages: 91-105
Publication
First Author: Mavrovic M
Year: 2020
Journal: EMBO Rep
Title: Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.
Volume: 21
Issue: 4
Pages: e48880
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Haapa S
Year: 1999
Journal: Genome Res
Title: An efficient DNA sequencing strategy based on the bacteriophage mu in vitro DNA transposition reaction.
Volume: 9
Issue: 3
Pages: 308-15
Publication
First Author: Uvarov P
Year: 2007
Journal: J Biol Chem
Title: A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2.
Volume: 282
Issue: 42
Pages: 30570-6
Publication
First Author: Moore YE
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures.
Volume: 115
Issue: 40
Pages: 10166-10171
Publication  
First Author: Moore YE
Year: 2019
Journal: Front Mol Neurosci
Title: Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function.
Volume: 12
Pages: 173
Publication
First Author: Vilen H
Year: 2001
Journal: Transgenic Res
Title: Construction of gene-targeting vectors: a rapid Mu in vitro DNA transposition-based strategy generating null, potentially hypomorphic, and conditional alleles.
Volume: 10
Issue: 1
Pages: 69-80
Publication
First Author: Li H
Year: 2007
Journal: Neuron
Title: KCC2 interacts with the dendritic cytoskeleton to promote spine development.
Volume: 56
Issue: 6
Pages: 1019-33
Publication  
First Author: Markkanen M
Year: 2017
Journal: Brain Res
Title: Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function.
Volume: 1675
Pages: 87-101
Publication
First Author: Llano O
Year: 2015
Journal: J Cell Biol
Title: KCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX.
Volume: 209
Issue: 5
Pages: 671-86
Publication
First Author: Woo NS
Year: 2002
Journal: Hippocampus
Title: Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene.
Volume: 12
Issue: 2
Pages: 258-68
Publication  
First Author: Pisella LI
Year: 2019
Journal: Sci Signal
Title: Impaired regulation of KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathology.
Volume: 12
Issue: 603
Publication  
First Author: Melón LC
Year: 2018
Journal: Psychoneuroendocrinology
Title: Inability to suppress the stress-induced activation of the HPA axis during the peripartum period engenders deficits in postpartum behaviors in mice.
Volume: 90
Pages: 182-193
Publication
First Author: Silayeva L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: KCC2 activity is critical in limiting the onset and severity of status epilepticus.
Volume: 112
Issue: 11
Pages: 3523-8
Publication    
First Author: Kontou G
Year: 2021
Journal: J Biol Chem
Title: KCC2 is required for the survival of mature neurons but not for their development.
Pages: 100364
Publication      
First Author: Kimmey BA
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: 5-HT2A receptor activation normalizes stress-induced dysregulation of GABAergic signaling in the ventral tegmental area.
Publication  
First Author: Kelley MR
Year: 2016
Journal: Neuropharmacology
Title: Compromising KCC2 transporter activity enhances the development of continuous seizure activity.
Volume: 108
Pages: 103-10
Publication  
First Author: MacKenzie G
Year: 2016
Journal: Epilepsy Res
Title: Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
Volume: 126
Pages: 185-96
Publication  
First Author: Dubois CJ
Year: 2018
Journal: eNeuro
Title: Role of the K+-Cl- Cotransporter KCC2a Isoform in Mammalian Respiration at Birth.
Volume: 5
Issue: 5
Publication
First Author: Bos R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2.
Volume: 110
Issue: 1
Pages: 348-53
Publication
First Author: Mahadevan V
Year: 2014
Journal: Cell Rep
Title: Kainate receptors coexist in a functional complex with KCC2 and regulate chloride homeostasis in hippocampal neurons.
Volume: 7
Issue: 6
Pages: 1762-70
Publication
First Author: Zhu L
Year: 2005
Journal: J Neurophysiol
Title: Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride.
Volume: 93
Issue: 3
Pages: 1557-68
Publication
First Author: Uvarov P
Year: 2009
Journal: J Biol Chem
Title: Coexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brain.
Volume: 284
Issue: 20
Pages: 13696-704
Publication
First Author: Boulenguez P
Year: 2010
Journal: Nat Med
Title: Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury.
Volume: 16
Issue: 3
Pages: 302-7
Publication
First Author: Balakrishnan V
Year: 2003
Journal: J Neurosci
Title: Expression and function of chloride transporters during development of inhibitory neurotransmission in the auditory brainstem.
Volume: 23
Issue: 10
Pages: 4134-45
Publication
First Author: Stil A
Year: 2011
Journal: Eur J Neurosci
Title: Contribution of the potassium-chloride co-transporter KCC2 to the modulation of lumbar spinal networks in mice.
Volume: 33
Issue: 7
Pages: 1212-22
Publication
First Author: Bortone D
Year: 2009
Journal: Neuron
Title: KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Volume: 62
Issue: 1
Pages: 53-71
Publication  
First Author: Gödde K
Year: 2016
Journal: Nat Commun
Title: Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination.
Volume: 7
Pages: 12043
Publication  
First Author: Kreis A
Year: 2023
Journal: Front Mol Neurosci
Title: Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory.
Volume: 16
Pages: 1081657
Publication
First Author: Yeo M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter.
Volume: 110
Issue: 11
Pages: 4315-20
Publication
First Author: Stein V
Year: 2004
Journal: J Comp Neurol
Title: Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride.
Volume: 468
Issue: 1
Pages: 57-64
Publication
First Author: Rivera C
Year: 2004
Journal: J Neurosci
Title: Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2.
Volume: 24
Issue: 19
Pages: 4683-91
Publication
First Author: Khirug S
Year: 2005
Journal: Eur J Neurosci
Title: Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices.
Volume: 21
Issue: 4
Pages: 899-904
Publication
First Author: Uvarov P
Year: 2005
Journal: J Neurochem
Title: Neuronal K+/Cl- co-transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone-specific expression and developmental up-regulation of endogenous KCC2 gene.
Volume: 95
Issue: 4
Pages: 1144-55
Publication
First Author: Takayama C
Year: 2006
Journal: Neuroscience
Title: Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation.
Volume: 143
Issue: 3
Pages: 757-67
Publication
First Author: Lee HH
Year: 2010
Journal: Mol Cell Neurosci
Title: Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2.
Volume: 45
Issue: 2
Pages: 173-9
Publication
First Author: Roussa E
Year: 2016
Journal: J Cell Sci
Title: The membrane trafficking and functionality of the K+-Cl- co-transporter KCC2 is regulated by TGF-β2.
Volume: 129
Issue: 18
Pages: 3485-98
Publication
First Author: Nakamura K
Year: 2019
Journal: J Physiol Sci
Title: Overexpression of neuronal K+-Cl- co-transporter enhances dendritic spine plasticity and motor learning.
Volume: 69
Issue: 3
Pages: 453-463
GXD Expression    
Probe: MGI:3641054
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:3641144
Age: embryonic day 18.0
Image: 8
Specimen Label: Control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3641054
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:3641144
Age: embryonic day 18.0
Image: 8
Specimen Label: Control
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5640703
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640806
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5640703
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640806
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6392856
Assay Type: Western blot
Annotation Date: 2020-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3705125
Stage: TS25
Assay Id: MGI:6392859
Age: embryonic day 17.5
Image: 2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267825
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Brainstem
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Cortex
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284525
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Hippocampus
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280925
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Olfactory bulb
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757725
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Spinal cord
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Kidney
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Liver
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:7356001
Age: embryonic day 17.0
Image: 4
Specimen Label: Lung
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267825
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Brainstem
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Cortex
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284525
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Hippocampus
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280925
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Olfactory bulb
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757725
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Spinal cord
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Kidney
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Liver
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:7356003
Age: embryonic day 17.0
Image: 4
Specimen Label: Lung
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Brainstem
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Cortex
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Hippocampus
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Olfactory bulb
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Spinal cord
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Kidney
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:7355995
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7356004
Age: postnatal day 14
Image: 4
Specimen Label: Lung
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7356006
Age: postnatal day 14
Image: 4
Specimen Label: Cortex
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7355997
Assay Type: RT-PCR
Annotation Date: 2022-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7356006
Age: postnatal day 14
Image: 4
Specimen Label: Hippocampus
Detected: true
Specimen Num: 4