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Search results 1 to 100 out of 116 for Slc24a4

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0.042s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Sodium/potassium/calcium exchanger 4, also know as NCKX4 or SLC24A4, is the fourth member of the potassium-dependent sodium-calcium exchanger family []. SLC24A4 transports 1 Ca2+ and 1 K+ in exchange for 4 Na+. It controls termination and adaptation of the mammalian olfactory response []. It also has a key role in calcium transport during enamel formation [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Parry DA
Year: 2013
Journal: Am J Hum Genet
Title: Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta.
Volume: 92
Issue: 2
Pages: 307-12
Publication
First Author: Li XF
Year: 2002
Journal: J Biol Chem
Title: Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4.
Volume: 277
Issue: 50
Pages: 48410-7
Publication
First Author: Stephan AB
Year: 2011
Journal: Nat Neurosci
Title: The Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response.
Volume: 15
Issue: 1
Pages: 131-7
Protein
Organism: Mus musculus/domesticus
Length: 586  
Fragment?: false
Publication
First Author: Wang S
Year: 2014
Journal: J Dent Res
Title: STIM1 and SLC24A4 Are Critical for Enamel Maturation.
Volume: 93
Issue: 7 Suppl
Pages: 94S-100S
Protein
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 605  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: false
Publication
First Author: Li XF
Year: 2014
Journal: J Biol Chem
Title: An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety.
Volume: 289
Issue: 37
Pages: 25445-59
Publication  
First Author: De Maria A
Year: 2018
Journal: Exp Eye Res
Title: Expression of potassium-dependent sodium-calcium exchanger in the murine lens.
Volume: 167
Pages: 18-24
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for spindly.
Publication  
First Author: Chan B
Year: 2023
Journal: Front Physiol
Title: Sodium/(calcium + potassium) exchanger NCKX4 optimizes KLK4 activity in the enamel matrix microenvironment to regulate ECM modeling.
Volume: 14
Pages: 1116091
Publication
First Author: Reisert J
Year: 2021
Journal: PLoS One
Title: Odor sampling strategies in mice with genetically altered olfactory responses.
Volume: 16
Issue: 5
Pages: e0249798
Publication
First Author: Bronckers AL
Year: 2017
Journal: Calcif Tissue Int
Title: Reduced Protein Expression of the Na+/Ca2++K+-Exchanger (SLC24A4) in Apical Plasma Membranes of Maturation Ameloblasts of Fluorotic Mice.
Volume: 100
Issue: 1
Pages: 80-86
GXD Expression    
Probe: MGI:6865713
Assay Type: RT-PCR
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:6865728
Age: postnatal month 1
Image: 1
Specimen Label: Slc24a4+/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6865713
Assay Type: RT-PCR
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:6865728
Age: postnatal month 1
Image: 1
Specimen Label: Slc24a4-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6865711
Assay Type: RT-PCR
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287128
Stage: TS28
Assay Id: MGI:6865721
Age: postnatal month 1
Image: 1
Specimen Label: epithelium
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6865711
Assay Type: RT-PCR
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784128
Stage: TS28
Assay Id: MGI:6865721
Age: postnatal month 1
Image: 1
Specimen Label: fibers
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633545
Specimen Label: MRC Harwell_633545
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6865730
Age: postnatal day 30
Image: 2B
Note: No expression in cells of organelle-free zone (OFZ) itself.
Specimen Label: 2B
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6865717
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6865731
Age: postnatal adult
Image: 3A/C
Note: Expression in both nucleated and non-nucleated regions of lens cortex.
Specimen Label: 3A/C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6865717
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6865731
Age: postnatal adult
Image: 3A/C
Note: Expression in both nucleated and non-nucleated regions of lens cortex.
Specimen Label: 3A/C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6865717
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:6865731
Age: postnatal adult
Image: 3D/F
Note: Expression reduced to low, background levels.
Specimen Label: 3D/F
Detected: false
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633549
Specimen Label: MRC Harwell_633549
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3287128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6865730
Age: postnatal day 30
Image: 2B
Note: Almost undertectable expression in epithelial cells.
Specimen Label: 2B
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3287124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6865730
Age: embryonic day 16.5
Image: 2A
Note: Almost undetectable expression in epithelial cells.
Specimen Label: 2A
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6865717
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287128
Stage: TS28
Assay Id: MGI:6865731
Age: postnatal adult
Image: 3A/C
Note: Near absent expression in lens epithelium.
Specimen Label: 3A/C
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633551
Specimen Label: MRC Harwell_633551
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633539
Specimen Label: MRC Harwell_633539
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1784124
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6865730
Age: embryonic day 16.5
Image: 2A
Note: Abundant expression in nucleated secondary lens fiber cells.
Specimen Label: 2A
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6865730
Age: postnatal day 30
Image: 2B
Note: Abundant expression in lens fiber cells, restricted to fibers in outer lens cortex. No expression in inner cortical region bordering the organelle-free zone (OFZ)
Specimen Label: 2B
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1784124
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6865730
Age: embryonic day 16.5
Image: 2A
Note: Low expression in central fiber cells undergoing undergoing nuclear degradation.
Specimen Label: 2A
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6865717
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6865731
Age: postnatal adult
Image: 3A/C
Note: Expression also in fiber cells within organelle-free zone (OFZ).
Specimen Label: 3A/C
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633553
Specimen Label: MRC Harwell_633553
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716520
Stage: TS20
Assay Id: MGI:6865730
Age: embryonic day 12.0
Specimen Label: E12 not shown
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633547
Specimen Label: MRC Harwell_633547
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633537
Specimen Label: MRC Harwell_633537
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633541
Specimen Label: MRC Harwell_633541
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692731
Age: postnatal adult
Image: MRC Harwell_633543
Specimen Label: MRC Harwell_633543
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6865715
Assay Type: RNA in situ
Annotation Date: 2022-02-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3813920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6865730
Age: embryonic day 12.0
Note: Strong expression in primary fiber cells as early as day 12.
Specimen Label: E12 not shown
Detected: true
Specimen Num: 1
Publication
First Author: Wang SK
Year: 2015
Journal: Mol Genet Genomic Med
Title: Critical roles for WDR72 in calcium transport and matrix protein removal during enamel maturation.
Volume: 3
Issue: 4
Pages: 302-19
Publication      
First Author: Thibodeau S
Year: 2020
Journal: J Biol Chem
Title: Calmodulin binds and modulates K+-dependent Na+/Ca2+-exchanger isoform 4, NCKX4.
Publication
First Author: Szerencsei RT
Year: 2016
Journal: Biochemistry
Title: Identification and Characterization of K(+)-Dependent Na(+)-Ca(2+) Exchange Transport in Pigmented MEB4 Cells Mediated by NCKX4.
Volume: 55
Issue: 19
Pages: 2704-12
Publication    
First Author: Vinberg F
Year: 2017
Journal: Elife
Title: The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision.
Volume: 6
Publication
First Author: Ferguson CH
Year: 2017
Journal: J Neurosci
Title: Simultaneous Loss of NCKX4 and CNG Channel Desensitization Impairs Olfactory Sensitivity.
Volume: 37
Issue: 1
Pages: 110-119
Publication
First Author: Bennett B
Year: 2007
Journal: Alcohol Clin Exp Res
Title: Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel.
Volume: 31
Issue: 2
Pages: 200-8
Publication
First Author: Bronckers AL
Year: 2015
Journal: J Dent Res
Title: Ameloblast Modulation and Transport of Cl⁻, Na⁺, and K⁺ during Amelogenesis.
Volume: 94
Issue: 12
Pages: 1740-7
Publication
First Author: Szeto IYY
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.
Volume: 119
Issue: 46
Pages: e2122121119
Publication
First Author: Saito K
Year: 2020
Journal: iScience
Title: Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ.
Volume: 23
Issue: 7
Pages: 101329
Publication  
First Author: Gong Y
Year: 2022
Journal: Cells
Title: Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.
Volume: 11
Issue: 11
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load