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Search results 1 to 100 out of 101 for Slc25a32

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
81034 | SLC25A32
Type: gene
Organism: human
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Gene
779525 | slc25a32
Type: gene
Organism: frog, western clawed
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Gene
315023 | Slc25a32
Type: gene
Organism: rat
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Gene
475064 | SLC25A32
Type: gene
Organism: dog, domestic
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Gene
742856 | SLC25A32
Type: gene
Organism: chimpanzee
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Gene
782162 | SLC25A32
Type: gene
Organism: cattle
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Gene
428377 | SLC25A32
Type: gene
Organism: chicken
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Gene
694759 | SLC25A32
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1917156 | Slc25a32
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
35727412 | J:338257
First Author: Peng MZ
Year: 2022
Journal: Cell Mol Life Sci
Title: Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
Volume: 79
Issue: 7
Pages: 375
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Publication
29666258 | J:261656
First Author: Kim J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Formate rescues neural tube defects caused by mutations in Slc25a32.
Volume: 115
Issue: 18
Pages: 4690-4695
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Protein Coding Gene
MGP_CAROLIEiJ_G0019756 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021780 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1917156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022219 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021649 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019765 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020653 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21768094 | J:359374
First Author: Lawrence SA
Year: 2011
Journal: J Biol Chem
Title: Tetrahydrofolate recognition by the mitochondrial folate transporter.
Volume: 286
Issue: 36
Pages: 31480-9
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Publication
10978331 | J:359366
First Author: Titus SA
Year: 2000
Journal: J Biol Chem
Title: Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria.
Volume: 275
Issue: 47
Pages: 36811-7
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GXD Expression
GXD Expression
   
Probe: MGI:6158639
Assay Type: RT-PCR
Annotation Date: 2018-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:6158640
Age: embryonic day 10.0
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6158639
Assay Type: RT-PCR
Annotation Date: 2018-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:6158640
Age: embryonic day 10.0
Image: 1
Specimen Label: +/gt
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6158639
Assay Type: RT-PCR
Annotation Date: 2018-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:6158640
Age: embryonic day 10.0
Image: 1
Specimen Label: gt/gt
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7572488
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572526
Age: postnatal month 2-3
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7572488
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572526
Age: postnatal month 2-3
Specimen Label: Y14C/Y174C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7572488
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572526
Age: postnatal month 2-3
Specimen Label: Y14C/K235R
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7572488
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572526
Age: postnatal month 2-3
Specimen Label: K235R/K235R
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7572489
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7572527
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7572489
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7572527
Age: embryonic day 11.5
Specimen Label: -/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7572489
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7572527
Age: embryonic day 11.5
Specimen Label: -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7572488
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7572528
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7572488
Assay Type: RT-PCR
Annotation Date: 2024-01-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7572528
Age: embryonic day 11.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: +/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: Y14C/Y174C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: Y14C/Y174C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: Y14C/K235R
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: Y14C/K235R
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: K235R/K235R
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7572509
Assay Type: Western blot
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7572530
Age: postnatal month 2-3
Specimen Label: K235R/K235R
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:1764896
Assay Type: RNA in situ
Annotation Date: 2011-02-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4888651
Age: embryonic day 14.5
Image: Table S1
Specimen Label: Table S1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Ubiquitous
Stage: TS15
Assay Id: MGI:6158643
Age: embryonic day 9.5
Image: 1E gt/gt
Specimen Label: 1E gt/gt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-05-29
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3185815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6158643
Age: embryonic day 9.5
Image: 1E gt/gt
Note: Authors report higher expression in cranial region than in posterior region or embryo.
Specimen Label: 1E gt/gt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4428432
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1725823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828156
Age: embryonic day 14.5
Image: euxassay_019723_10
Specimen Label: euxassay_019723_10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4428432
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1725823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828156
Age: embryonic day 14.5
Image: euxassay_019723_11
Specimen Label: euxassay_019723_11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4428432
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1725823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828156
Age: embryonic day 14.5
Image: euxassay_019723_12
Specimen Label: euxassay_019723_12
Detected: true
Specimen Num: 3
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Slc25a32<em1Smoc> | MGI:7292391
Name: solute carrier family 25, member 32; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6771168 | C57BL/6JSmoc-Slc25a32<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
15140890 | -
First Author: McCarthy EA
Year: 2004
Journal: J Biol Chem
Title: A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cells.
Volume: 279
Issue: 32
Pages: 33829-36
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Publication
16165386 | -
First Author: Spaan AN
Year: 2005
Journal: Mol Genet Metab
Title: Identification of the human mitochondrial FAD transporter and its potential role in multiple acyl-CoA dehydrogenase deficiency.
Volume: 86
Issue: 4
Pages: 441-7
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Publication
19745225 | -
First Author: Palmieri F
Year: 2009
Journal: J Biol Chem
Title: Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins.
Volume: 284
Issue: 45
Pages: 31249-59
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Publication
32650612 | -
 
First Author: Fernie AR
Year: 2020
Journal: Biomolecules
Title: Metabolic Roles of Plant Mitochondrial Carriers.
Volume: 10
Issue: 7
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Publication
16055441 | -
First Author: Bedhomme M
Year: 2005
Journal: J Biol Chem
Title: Folate metabolism in plants: an Arabidopsis homolog of the mammalian mitochondrial folate transporter mediates folate import into chloroplasts.
Volume: 280
Issue: 41
Pages: 34823-31
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Publication
32906142 | J:299941
First Author: Luongo TS
Year: 2020
Journal: Nature
Title: SLC25A51 is a mammalian mitochondrial NAD+ transporter.
Volume: 588
Issue: 7836
Pages: 174-179
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Publication
16291748 | -
First Author: Todisco S
Year: 2006
Journal: J Biol Chem
Title: Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae.
Volume: 281
Issue: 3
Pages: 1524-31
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Publication
14555654 | -
First Author: Bafunno V
Year: 2004
Journal: J Biol Chem
Title: Riboflavin uptake and FAD synthesis in Saccharomyces cerevisiae mitochondria: involvement of the Flx1p carrier in FAD export.
Volume: 279
Issue: 1
Pages: 95-102
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Publication
8631763 | -
First Author: Tzagoloff A
Year: 1996
Journal: J Biol Chem
Title: FLX1 codes for a carrier protein involved in maintaining a proper balance of flavin nucleotides in yeast mitochondria.
Volume: 271
Issue: 13
Pages: 7392-7
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Protein Domain
IPR044712 | SLC25A32-like
Type: Family
Description: This entry represents a group of substrate carrier proteins that are related to the nicotinamide adenine dinucleotide transporter found in mitochondria, including human NAD/FAD transporter SLC25A32, yeast Yea6/Flx1/Yia6, and AtNDT1/AtNDT2/PXN/AtFOLT1 from Arabidopsis. Structurally, they consist of three tandem repeats of a domain of approximately one hundred residues. Each of these domains contains two transmembrane regions.In budding yeasts, Yea6 and Yia6 are mitochondrial inner membrane carrier protein that mediates the import of NAD+ into mitochondria [, ]. Flx1 transports FAD from the cytosol to the mitochondrial matrix [, ].In humans, SLC25A32 transports folate and FAD across the inner membranes of mitochondria [, , ]. Mutations in the SLC25A32 gene cause neural tube defects (NTD) []. SLC25A32 has also been implicated in multiple acyl-CoA dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) []. In Arabidopsis, AtNDT1 and AtNDT2 are able to catalyze the import of NAD+ in mitochondria []. PXN (At2g39970) is a peroxisomal NAD carrier that is able to catalyze NAD, NADH, AMP, ADP, adenosine 3', 5'-phosphate (PAP) and CoA transport. It supplies the peroxisomes with NAD by importing this coenzyme from the cytosol in exchange with AMP []. AtFOLT1 (At5g66380) has been shown to mediate folate import into chloroplast [].
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Protein
Q8BMG8
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
Q8K0B7
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
A0A2I3BQL2
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
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Protein
Q3UM21
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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