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Search results 1 to 100 out of 111 for Slc26a3

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Type Details Score
Gene
1811 | SLC26A3
Type: gene
Organism: human
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Gene
512856 | SLC26A3
Type: gene
Organism: cattle
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Gene
417700 | SLC26A3
Type: gene
Organism: chicken
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Gene
701873 | SLC26A3
Type: gene
Organism: macaque, rhesus
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Gene
114629 | Slc26a3
Type: gene
Organism: rat
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Gene
483261 | SLC26A3
Type: gene
Organism: dog, domestic
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Gene
472483 | SLC26A3
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:107181 | Slc26a3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030321 | SLC26A3
Type: Family
Description: SLC26A3 or DRA (Down Regulated in Adenoma) is a member of the solute carrier family 26 (SLC26) that plays a major role in mediating Cl-absorption in the intestine. DRA absorbs Cl- and exports HCO3-in the small intestine in a partly carbonic anhydrase II-dependent fashion []. DRA also contributes to sulfate secretion []. Deletion of DRA results in reduced colonic HCO3-secretion, loss of colonic fluid absorption, and a lack of adherent mucus layer []. Mutations in DRA cause congenital chloride diarrhea, characterised by chronic secretory diarrhea containing an excess of chloride [].DRA is also involved in sperm capacitation [, ].
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Publication
21976599 | J:185780
First Author: Chávez JC
Year: 2012
Journal: Biol Reprod
Title: Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation.
Volume: 86
Issue: 1
Pages: 1-14
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Publication
24233434 | J:243842
First Author: Xia W
Year: 2014
Journal: Pflugers Arch
Title: The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.
Volume: 466
Issue: 8
Pages: 1541-56
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Publication
23660504 | J:204021
First Author: Whittamore JM
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Sulfate secretion and chloride absorption are mediated by the anion exchanger DRA (Slc26a3) in the mouse cecum.
Volume: 305
Issue: 2
Pages: G172-84
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Protein
Q8R224
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
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Protein
Q8JZU8
Organism: Mus musculus/domesticus
Length: 301  
Fragment?: false
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Publication
22627094 | J:333132
First Author: Lee JH
Year: 2012
Journal: Cell Signal
Title: Regulation of SLC26A3 activity by NHERF4 PDZ-mediated interaction.
Volume: 24
Issue: 9
Pages: 1821-30
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Publication
21394828 | -
First Author: Wedenoja S
Year: 2011
Journal: Hum Mutat
Title: Update on SLC26A3 mutations in congenital chloride diarrhea.
Volume: 32
Issue: 7
Pages: 715-22
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Publication
24177028 | J:210909
First Author: Anbazhagan AN
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Translational repression of SLC26A3 by miR-494 in intestinal epithelial cells.
Volume: 306
Issue: 2
Pages: G123-31
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Publication
28572085 | J:253734
First Author: Chatterjee I
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: CDX2 upregulates SLC26A3 gene expression in intestinal epithelial cells.
Volume: 313
Issue: 3
Pages: G256-G264
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Publication
30118583 | J:307576
First Author: El Khouri E
Year: 2018
Journal: Mol Reprod Dev
Title: Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.
Volume: 85
Issue: 8-9
Pages: 682-695
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Publication
33189700 | J:313177
First Author: Kumar A
Year: 2021
Journal: Gastroenterology
Title: A Novel Role of SLC26A3 in the Maintenance of Intestinal Epithelial Barrier Integrity.
Volume: 160
Issue: 4
Pages: 1240-1255.e3
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Publication
17001077 | J:117587
First Author: Schweinfest CW
Year: 2006
Journal: J Biol Chem
Title: slc26a3 (dra)-deficient mice display chloride-losing diarrhea, enhanced colonic proliferation, and distinct up-regulation of ion transporters in the colon.
Volume: 281
Issue: 49
Pages: 37962-71
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Publication
24373192 | -
First Author: Xiao F
Year: 2014
Journal: Acta Physiol (Oxf)
Title: Slc26a3 deficiency is associated with loss of colonic HCO3 (-) secretion, absence of a firm mucus layer and barrier impairment in mice.
Volume: 211
Issue: 1
Pages: 161-75
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Publication
19546193 | J:152260
First Author: Borenshtein D
Year: 2009
Journal: Infect Immun
Title: Decreased expression of colonic Slc26a3 and carbonic anhydrase iv as a cause of fatal infectious diarrhea in mice.
Volume: 77
Issue: 9
Pages: 3639-50
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Publication
21068358 | J:168506
First Author: Alper SL
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange.
Volume: 300
Issue: 2
Pages: C276-86
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Publication
24115633 | -
First Author: Chan HC
Year: 2014
Journal: Cell Biol Int
Title: SLC26 anion exchangers in uterine epithelial cells and spermatozoa: clues from the past and hints to the future.
Volume: 38
Issue: 1
Pages: 1-7
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Protein
E9QAZ3
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: true
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Protein
Q9WVC8
Organism: Mus musculus/domesticus
Length: 757  
Fragment?: false
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Publication
23886857 | J:210569
First Author: Freel RW
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Transcellular oxalate and Cl- absorption in mouse intestine is mediated by the DRA anion exchanger Slc26a3, and DRA deletion decreases urinary oxalate.
Volume: 305
Issue: 7
Pages: G520-7
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Publication
16901991 | J:120597
First Author: Ishiguro H
Year: 2007
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Effect of Slc26a6 deletion on apical Cl-/HCO3- exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct.
Volume: 292
Issue: 1
Pages: G447-55
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Publication
17170027 | J:121543
First Author: Simpson JE
Year: 2007
Journal: Am J Physiol Gastrointest Liver Physiol
Title: PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.
Volume: 292
Issue: 4
Pages: G1079-88
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Publication
27118869 | J:239473
First Author: Bhutia YD
Year: 2016
Journal: Biochem J
Title: SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms.
Volume: 473
Issue: 9
Pages: 1113-24
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Publication
20164375 | J:159251
First Author: Singh AK
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.
Volume: 298
Issue: 5
Pages: C1057-65
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Publication
20969732 | J:333128
First Author: Walker NM
Year: 2011
Journal: Acta Physiol (Oxf)
Title: Functional activity of Pat-1 (Slc26a6) Cl(−)/HCO₃(−) exchange in the lower villus epithelium of murine duodenum.
Volume: 201
Issue: 1
Pages: 21-31
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Publication
24018950 | J:215845
First Author: Singh AK
Year: 2013
Journal: J Physiol
Title: Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.
Volume: 591
Issue: 21
Pages: 5377-91
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Publication
22674389 | J:192414
First Author: Dawson PA
Year: 2012
Journal: Biol Reprod
Title: Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.
Volume: 87
Issue: 2
Pages: 43
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Protein Coding Gene
MGP_CAROLIEiJ_G0017676 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019660 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019604 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018963 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019379 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019493 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019563 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019519 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029434 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018518 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
30615234 | J:277389
First Author: Stephens CE
Year: 2019
Journal: Exp Physiol
Title: 125 Iodide as a surrogate tracer for epithelial chloride transport by the mouse large intestine in vitro.
Volume: 104
Issue: 3
Pages: 334-344
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Publication
10803366 | J:60762
First Author: Kunieda T
Year: 2000
Journal: Exp Anim
Title: The down-regulated in adenoma (Dra) gene encoding intestine-specific anion transporter maps to mouse chromosome 12.
Volume: 49
Issue: 1
Pages: 67-8
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Publication
7744840 | J:25525
First Author: Silberg DG
Year: 1995
Journal: J Biol Chem
Title: The Down regulated in Adenoma (dra) gene encodes an intestine-specific membrane sulfate transport protein.
Volume: 270
Issue: 20
Pages: 11897-902
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Publication
11875004 | J:75017
First Author: Jacob P
Year: 2002
Journal: Gastroenterology
Title: Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenum.
Volume: 122
Issue: 3
Pages: 709-24
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Publication
31634391 | J:305508
First Author: Priyamvada S
Year: 2020
Journal: Inflamm Bowel Dis
Title: All-trans Retinoic Acid Counteracts Diarrhea and Inhibition of Downregulated in Adenoma Expression in Gut Inflammation.
Volume: 26
Issue: 4
Pages: 534-545
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GXD Expression
GXD Expression
   
Probe: MGI:4425674
Assay Type: RNA in situ
Annotation Date: 2011-02-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4888656
Age: embryonic day 14.5
Image: Table S1
Specimen Label: Table S1
Detected: false
Specimen Num: 1
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Publication
10428871 | J:56643
First Author: Melvin JE
Year: 1999
Journal: J Biol Chem
Title: Mouse down-regulated in adenoma (DRA) is an intestinal Cl(-)/HCO(3)(-) exchanger and is up-regulated in colon of mice lacking the NHE3 Na(+)/H(+) exchanger.
Volume: 274
Issue: 32
Pages: 22855-61
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Publication
26394631 | J:288339
First Author: Jalali R
Year: 2015
Journal: J Dent Res
Title: Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.
Volume: 94
Issue: 12
Pages: 1732-9
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Publication
28526688 | J:250103
First Author: Whittamore JM
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of the anion exchanger DRA (Slc26a3), or PAT1 (Slc26a6), alters sulfate transport by the distal ileum and overall sulfate homeostasis.
Volume: 313
Issue: 3
Pages: G166-G179
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Publication
22895259 | J:192779
First Author: Song Y
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.
Volume: 303
Issue: 8
Pages: C815-24
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Publication
19121635 | J:146913
First Author: Walker NM
Year: 2009
Journal: Gastroenterology
Title: Role of down-regulated in adenoma anion exchanger in HCO3- secretion across murine duodenum.
Volume: 136
Issue: 3
Pages: 893-901
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Publication
18930060 | J:145623
First Author: Walker NM
Year: 2008
Journal: Gastroenterology
Title: Down-regulated in adenoma Cl/HCO3 exchanger couples with Na/H exchanger 3 for NaCl absorption in murine small intestine.
Volume: 135
Issue: 5
Pages: 1645-1653.e3
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Publication
11597142 | J:72227
First Author: Kratz CP
Year: 2001
Journal: Genomics
Title: Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies.
Volume: 77
Issue: 3
Pages: 171-80
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Publication
20388655 | J:160162
First Author: D'Angelo A
Year: 2010
Journal: Development
Title: Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium.
Volume: 137
Issue: 9
Pages: 1573-82
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Publication
27371534 | J:291945
First Author: De Arcangelis A
Year: 2017
Journal: Gut
Title: Hemidesmosome integrity protects the colon against colitis and colorectal cancer.
Volume: 66
Issue: 10
Pages: 1748-1760
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Publication
28818950 | J:244916
First Author: Zhao F
Year: 2017
Journal: Science
Title: Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice.
Volume: 357
Issue: 6352
Pages: 717-720
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Publication
37471646 | J:342643
First Author: Oh Y
Year: 2023
Journal: Biol Reprod
Title: Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice†.
Volume: 109
Issue: 4
Pages: 520-532
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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