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Search results 1 to 100 out of 121 for Slc26a6

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
443591 | slc26a6
Type: gene
Organism: frog, African clawed
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Gene
65010 | SLC26A6
Type: gene
Organism: human
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Gene
301010 | Slc26a6
Type: gene
Organism: rat
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Gene
514514 | SLC26A6
Type: gene
Organism: cattle
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Gene
100613198 | SLC26A6
Type: gene
Organism: chimpanzee
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Gene
416012 | SLC26A6
Type: gene
Organism: chicken
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Gene
100005108 | slc26a6
Type: gene
Organism: zebrafish
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Gene
558704 | slc26a6
Type: gene
Organism: zebrafish
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Gene
780378 | slc26a6
Type: gene
Organism: frog, western clawed
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Gene
106996923 | SLC26A6
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR030323 | SLC26A6
Type: Family
Description: SLC26A6 or PAT1 is a member of the solute carrier family 26 (SLC26) that plays an important role in jejunal Na+HCO3- reabsorption []. It contributes to intracellular pH regulation during H+-dipeptide transport in duodenal epithelium []. It is also involved in sperm capacitation [, ]. PAT1 is a versatile transporter mediating Cl-/HCO3- exchange, Cl-/oxalate and Cl-/formate exchange and Cl-/sulfate exchange [, , ].
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Protein Coding Gene
MGI:2159728 | Slc26a6
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24233434 | J:243842
First Author: Xia W
Year: 2014
Journal: Pflugers Arch
Title: The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.
Volume: 466
Issue: 8
Pages: 1541-56
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Publication
20150244 | J:159253
First Author: Simpson JE
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Putative anion transporter-1 (Pat-1, Slc26a6) contributes to intracellular pH regulation during H+-dipeptide transport in duodenal villous epithelium.
Volume: 298
Issue: 5
Pages: G683-91
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Publication
11459928 | J:75064
First Author: Knauf F
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells.
Volume: 98
Issue: 16
Pages: 9425-30
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Publication
21976599 | J:185780
First Author: Chávez JC
Year: 2012
Journal: Biol Reprod
Title: Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation.
Volume: 86
Issue: 1
Pages: 1-14
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Publication
26394631 | J:288339
First Author: Jalali R
Year: 2015
Journal: J Dent Res
Title: Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.
Volume: 94
Issue: 12
Pages: 1732-9
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Publication
17151144 | J:201564
First Author: Hassan HA
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: Regulation of anion exchanger Slc26a6 by protein kinase C.
Volume: 292
Issue: 4
Pages: C1485-92
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Publication
23933580 | J:333163
First Author: Kim HJ
Year: 2013
Journal: Cardiovasc Res
Title: Slc26a6 functions as an electrogenic Cl-/HCO3- exchanger in cardiac myocytes.
Volume: 100
Issue: 3
Pages: 383-91
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Publication
22594923 | J:331851
First Author: Garcia-Perez I
Year: 2012
Journal: J Proteome Res
Title: Urinary metabolic phenotyping the slc26a6 (chloride-oxalate exchanger) null mouse model.
Volume: 11
Issue: 9
Pages: 4425-35
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Publication
16472591 | J:124935
First Author: Tuo B
Year: 2006
Journal: Gastroenterology
Title: Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion.
Volume: 130
Issue: 2
Pages: 349-58
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Publication
16373425 | J:109113
First Author: Freel RW
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Ileal oxalate absorption and urinary oxalate excretion are enhanced in Slc26a6 null mice.
Volume: 290
Issue: 4
Pages: G719-28
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Publication
29530983 | J:263699
First Author: Mukaibo T
Year: 2018
Journal: J Biol Chem
Title: The apical anion exchanger Slc26a6 promotes oxalate secretion by murine submandibular gland acinar cells.
Volume: 293
Issue: 17
Pages: 6259-6268
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Publication
12217875 | J:79463
First Author: Xie Q
Year: 2002
Journal: Am J Physiol Renal Physiol
Title: Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1.
Volume: 283
Issue: 4
Pages: F826-38
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Publication
16901991 | J:120597
First Author: Ishiguro H
Year: 2007
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Effect of Slc26a6 deletion on apical Cl-/HCO3- exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct.
Volume: 292
Issue: 1
Pages: G447-55
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Publication
17053783 | J:144457
First Author: Wang Y
Year: 2006
Journal: EMBO J
Title: Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3- secretion: relevance to cystic fibrosis.
Volume: 25
Issue: 21
Pages: 5049-57
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Publication
31532720 | J:282103
First Author: Munemasa T
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Slc26a6 is an apical membrane anion exchanger that drives HCO3--dependent fluid secretion in murine pancreatic acinar cells.
Volume: 317
Issue: 6
Pages: C1153-C1160
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Publication
22895259 | J:192779
First Author: Song Y
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.
Volume: 303
Issue: 8
Pages: C815-24
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Publication
18565999 | J:176390
First Author: Shcheynikov N
Year: 2008
Journal: J Physiol
Title: The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct.
Volume: 586
Issue: 16
Pages: 3813-24
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Publication
24384768 | -
First Author: Brzica H
Year: 2013
Journal: Arh Hig Rada Toksikol
Title: Oxalate: from the environment to kidney stones.
Volume: 64
Issue: 4
Pages: 609-30
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Publication
24115633 | -
First Author: Chan HC
Year: 2014
Journal: Cell Biol Int
Title: SLC26 anion exchangers in uterine epithelial cells and spermatozoa: clues from the past and hints to the future.
Volume: 38
Issue: 1
Pages: 1-7
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Publication
23506885 | -
First Author: Alper SL
Year: 2013
Journal: Mol Aspects Med
Title: The SLC26 gene family of anion transporters and channels.
Volume: 34
Issue: 2-3
Pages: 494-515
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Protein
A0A0A6YWP3
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
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Protein
A0A0A6YW61
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
A0A087WS07
Organism: Mus musculus/domesticus
Length: 628  
Fragment?: true
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Protein
Q8CIW6
Organism: Mus musculus/domesticus
Length: 758  
Fragment?: false
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Publication
16532010 | J:107558
First Author: Jiang Z
Year: 2006
Journal: Nat Genet
Title: Calcium oxalate urolithiasis in mice lacking anion transporter Slc26a6.
Volume: 38
Issue: 4
Pages: 474-8
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Publication
12119287 | J:201569
First Author: Jiang Z
Year: 2002
Journal: J Biol Chem
Title: Specificity of anion exchange mediated by mouse Slc26a6.
Volume: 277
Issue: 37
Pages: 33963-7
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Publication
16606687 | J:333127
First Author: Shcheynikov N
Year: 2006
Journal: J Gen Physiol
Title: Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6.
Volume: 127
Issue: 5
Pages: 511-24
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Publication
22021714 | J:201940
First Author: Knauf F
Year: 2011
Journal: J Am Soc Nephrol
Title: Net intestinal transport of oxalate reflects passive absorption and SLC26A6-mediated secretion.
Volume: 22
Issue: 12
Pages: 2247-55
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Publication
29025768 | J:302778
 
First Author: Sirish P
Year: 2017
Journal: Circ Arrhythm Electrophysiol
Title: Action Potential Shortening and Impairment of Cardiac Function by Ablation of Slc26a6.
Volume: 10
Issue: 10
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Publication
30427220 | J:281331
First Author: Knauf F
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Characterization of renal NaCl and oxalate transport in Slc26a6-/- mice.
Volume: 316
Issue: 1
Pages: F128-F133
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Publication
30728179 | J:292809
     
First Author: Khamaysi A
Year: 2019
Journal: J Am Soc Nephrol
Title: Systemic Succinate Homeostasis and Local Succinate Signaling Affect Blood Pressure and Modify Risks for Calcium Oxalate Lithogenesis.
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Publication
15574486 | J:101233
First Author: Wang Z
Year: 2005
Journal: Am J Physiol Cell Physiol
Title: Renal and intestinal transport defects in Slc26a6-null mice.
Volume: 288
Issue: 4
Pages: C957-65
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Publication
18174209 | J:176404
First Author: Clark JS
Year: 2008
Journal: J Physiol
Title: Species differences in Cl- affinity and in electrogenicity of SLC26A6-mediated oxalate/Cl- exchange correlate with the distinct human and mouse susceptibilities to nephrolithiasis.
Volume: 586
Issue: 5
Pages: 1291-306
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Publication
18496516 | J:152870
First Author: Singh AK
Year: 2008
Journal: Kidney Int
Title: Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5.
Volume: 74
Issue: 4
Pages: 438-47
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Publication
22517357 | J:191157
First Author: Ko N
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Sat1 is dispensable for active oxalate secretion in mouse duodenum.
Volume: 303
Issue: 1
Pages: C52-7
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Publication
17170027 | J:121543
First Author: Simpson JE
Year: 2007
Journal: Am J Physiol Gastrointest Liver Physiol
Title: PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.
Volume: 292
Issue: 4
Pages: G1079-88
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Publication
26671068 | J:239998
First Author: Yin K
Year: 2015
Journal: PLoS One
Title: SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.
Volume: 10
Issue: 12
Pages: e0144703
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Publication
20164375 | J:159251
First Author: Singh AK
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.
Volume: 298
Issue: 5
Pages: C1057-65
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Publication
24018950 | J:215845
First Author: Singh AK
Year: 2013
Journal: J Physiol
Title: Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.
Volume: 591
Issue: 21
Pages: 5377-91
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Publication
22674389 | J:192414
First Author: Dawson PA
Year: 2012
Journal: Biol Reprod
Title: Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.
Volume: 87
Issue: 2
Pages: 43
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Publication
23542070 | J:220505
First Author: Park S
Year: 2013
Journal: Gastroenterology
Title: Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.
Volume: 145
Issue: 1
Pages: 232-41
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Protein Coding Gene
MGP_CAROLIEiJ_G0032706 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035315 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035294 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035288 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2159728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035808 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034309 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034966 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035075 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035829 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015574 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033851 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15203903 | J:333178
First Author: Nozawa T
Year: 2004
Journal: J Drug Target
Title: Role of anion exchange transporter PAT1 (SLC26A6) in intestinal absorption of organic anions.
Volume: 12
Issue: 2
Pages: 97-104
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Publication
11842009 | J:75548
First Author: Wang Z
Year: 2002
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Identification of an apical Cl(-)/HCO3(-) exchanger in the small intestine.
Volume: 282
Issue: 3
Pages: G573-9
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Publication
12381535 | J:108276
First Author: Petrovic S
Year: 2002
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Colocalization of the apical Cl-/HCO3- exchanger PAT1 and gastric H-K-ATPase in stomach parietal cells.
Volume: 283
Issue: 5
Pages: G1207-16
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GXD Expression
GXD Expression
   
Probe: MGI:995357
Assay Type: RNA in situ
Annotation Date: 2011-02-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4888672
Age: embryonic day 14.5
Image: Table S1
Specimen Label: Table S1
Detected: false
Specimen Num: 1
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Publication
23660504 | J:204021
First Author: Whittamore JM
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Sulfate secretion and chloride absorption are mediated by the anion exchanger DRA (Slc26a3) in the mouse cecum.
Volume: 305
Issue: 2
Pages: G172-84
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Publication
28526688 | J:250103
First Author: Whittamore JM
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of the anion exchanger DRA (Slc26a3), or PAT1 (Slc26a6), alters sulfate transport by the distal ileum and overall sulfate homeostasis.
Volume: 313
Issue: 3
Pages: G166-G179
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Publication
30118583 | J:307576
First Author: El Khouri E
Year: 2018
Journal: Mol Reprod Dev
Title: Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.
Volume: 85
Issue: 8-9
Pages: 682-695
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Publication
16141316 | J:101422
First Author: Thomson RB
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Role of PDZK1 in membrane expression of renal brush border ion exchangers.
Volume: 102
Issue: 37
Pages: 13331-6
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Publication
20969732 | J:333128
First Author: Walker NM
Year: 2011
Journal: Acta Physiol (Oxf)
Title: Functional activity of Pat-1 (Slc26a6) Cl(−)/HCO₃(−) exchange in the lower villus epithelium of murine duodenum.
Volume: 201
Issue: 1
Pages: 21-31
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Publication
19121635 | J:146913
First Author: Walker NM
Year: 2009
Journal: Gastroenterology
Title: Role of down-regulated in adenoma anion exchanger in HCO3- secretion across murine duodenum.
Volume: 136
Issue: 3
Pages: 893-901
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Publication
21068358 | J:168506
First Author: Alper SL
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange.
Volume: 300
Issue: 2
Pages: C276-86
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Publication
18930060 | J:145623
First Author: Walker NM
Year: 2008
Journal: Gastroenterology
Title: Down-regulated in adenoma Cl/HCO3 exchanger couples with Na/H exchanger 3 for NaCl absorption in murine small intestine.
Volume: 135
Issue: 5
Pages: 1645-1653.e3
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Publication
19033647 | J:144738
First Author: Yang D
Year: 2009
Journal: J Clin Invest
Title: IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct.
Volume: 119
Issue: 1
Pages: 193-202
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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