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Search results 1 to 100 out of 423 for Slc7a11

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
23657 | SLC7A11
Type: gene
Organism: human
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Gene
100496726 | slc7a11
Type: gene
Organism: frog, western clawed
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Gene
310392 | Slc7a11
Type: gene
Organism: rat
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Gene
483821 | SLC7A11
Type: gene
Organism: dog, domestic
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Gene
471310 | SLC7A11
Type: gene
Organism: chimpanzee
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Gene
524078 | SLC7A11
Type: gene
Organism: cattle
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Gene
428731 | SLC7A11
Type: gene
Organism: chicken
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Gene
100151597 | slc7a11
Type: gene
Organism: zebrafish
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Gene
696516 | SLC7A11
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1347355 | Slc7a11
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
641364 | SLC7A11-AS1
Type: gene
Organism: human
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Gene
143222015 | FERRISR
Type: gene
Organism: human
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Gene
144248949 | SLC7A11-AS2
Type: gene
Organism: human
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Publication
40280132 | J:370119
First Author: Zhou N
Year: 2025
Journal: Cell
Title: SLC7A11 is an unconventional H(+) transporter in lysosomes.
Volume: 188
Issue: 13
Pages: 3441-3458.e25
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Publication
38641223 | J:387659
 
First Author: Kou Z
Year: 2024
Journal: Toxicol Appl Pharmacol
Title: AhR signaling modulates Ferroptosis by regulating SLC7A11 expression.
Volume: 486
Pages: 116936
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Publication
16037214 | J:100476
First Author: Chintala S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells.
Volume: 102
Issue: 31
Pages: 10964-9
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Publication
35614212 | J:330600
First Author: Maschalidi S
Year: 2022
Journal: Nature
Title: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.
Volume: 606
Issue: 7915
Pages: 776-784
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Publication
36996941 | J:360687
First Author: He F
Year: 2023
Journal: J Hepatol
Title: ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis.
Volume: 79
Issue: 2
Pages: 362-377
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Publication
38725861 | J:352020
First Author: Yang B
Year: 2024
Journal: Int J Biol Sci
Title: Aberrant Expression of SLC7A11 Impairs the Antimicrobial Activities of Macrophages in Staphylococcus Aureus Osteomyelitis in Mice.
Volume: 20
Issue: 7
Pages: 2555-2575
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Publication
23404113 | J:214918
First Author: Ananth S
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.
Volume: 54
Issue: 3
Pages: 1592-602
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Publication
34747522 | J:352704
First Author: Sears SMS
Year: 2021
Journal: J Neurosci Res
Title: Hyperexcitability and brain morphological differences in mice lacking the cystine/glutamate antiporter, system x(c)().
Volume: 99
Issue: 12
Pages: 3339-3353
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Publication
24548853 | J:208250
 
First Author: McCullagh EA
Year: 2014
Journal: Behav Brain Res
Title: Behavioral characterization of system xc- mutant mice.
Volume: 265
Pages: 1-11
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Publication
33390840 | J:309593
First Author: Huang Y
Year: 2021
Journal: Int J Biol Sci
Title: Ferroptosis in a sarcopenia model of senescence accelerated mouse prone 8 (SAMP8).
Volume: 17
Issue: 1
Pages: 151-162
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Publication
35398053 | J:324717
 
First Author: Liu Z
Year: 2022
Journal: Mol Cell Endocrinol
Title: The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells.
Volume: 549
Pages: 111641
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Publication
36417872 | J:344160
First Author: Aloi MS
Year: 2022
Journal: Cell Rep
Title: Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice.
Volume: 41
Issue: 8
Pages: 111696
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Publication
41175867 | J:389488
First Author: Drekolia MK
Year: 2026
Journal: Cell Metab
Title: Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation.
Volume: 38
Issue: 1
Pages: 115-134.e20
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Publication
37649973 | J:340513
 
First Author: Frare C
Year: 2023
Journal: Front Behav Neurosci
Title: Sex- and age-dependent contribution of System x(c)(-) to cognitive, sensory, and social behaviors revealed by comprehensive behavioral analyses of System x(c)(-) null mice.
Volume: 17
Pages: 1238349
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Publication
32349646 | J:310342
First Author: Fang X
Year: 2020
Journal: Circ Res
Title: Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis.
Volume: 127
Issue: 4
Pages: 486-501
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Publication
25799988 | J:220466
First Author: Jiang L
Year: 2015
Journal: Nature
Title: Ferroptosis as a p53-mediated activity during tumour suppression.
Volume: 520
Issue: 7545
Pages: 57-62
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Publication
20645408 | J:392565
First Author: Jackman NA
Year: 2010
Journal: Glia
Title: Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1??: implications for hypoxic neuronal injury.
Volume: 58
Issue: 15
Pages: 1806-15
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Publication
38605214 | J:359018
First Author: Cao N
Year: 2024
Journal: Oncogene
Title: LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis.
Volume: 43
Issue: 22
Pages: 1714-1725
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Publication
31929527 | J:284068
First Author: Zhang T
Year: 2020
Journal: PLoS Genet
Title: High-throughput discovery of genetic determinants of circadian misalignment.
Volume: 16
Issue: 1
Pages: e1008577
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Publication
19715555 | J:157811
First Author: Gnana-Prakasam JP
Year: 2009
Journal: Biochem J
Title: Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger.
Volume: 424
Issue: 2
Pages: 243-52
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Publication
41034585 | J:372794
First Author: Chi F
Year: 2025
Journal: Nature
Title: Dietary cysteine enhances intestinal stemness via CD8(+) T cell-derived IL-22.
Volume: 647
Issue: 8090
Pages: 706-715
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Publication
42315151 | J:392167
     
First Author: Shim YR
Year: 2026
Journal: Clin Mol Hepatol
Title: Glutamate excreted by LepR??? BM-MSCs mitigates alcohol-associated liver disease by promoting IL-1R2??? monocyte migration.
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Publication
21943374 | J:179221
First Author: Gnana-Prakasam JP
Year: 2012
Journal: Biochem J
Title: Iron-mediated retinal degeneration in haemojuvelin-knockout mice.
Volume: 441
Issue: 2
Pages: 599-608
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Protein Coding Gene
MGP_CAROLIEiJ_G0024970 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200000357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195000687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220015704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180000362 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175002078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1347355 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215000495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005009249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210000476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185000242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205009359 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230000287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000016003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190000182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225015953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010009164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005000376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026411 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010007000 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10206947 | J:54626
First Author: Sato H
Year: 1999
Journal: J Biol Chem
Title: Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins.
Volume: 274
Issue: 17
Pages: 11455-8
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Publication
16144837 | J:102902
First Author: Sato H
Year: 2005
Journal: J Biol Chem
Title: Redox imbalance in cystine/glutamate transporter-deficient mice.
Volume: 280
Issue: 45
Pages: 37423-9
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Publication
17035536 | J:113249
First Author: Shih AY
Year: 2006
Journal: J Neurosci
Title: Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.
Volume: 26
Issue: 41
Pages: 10514-23
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Publication
17200146 | J:121453
First Author: Sakakura Y
Year: 2007
Journal: J Leukoc Biol
Title: Expression and function of cystine/glutamate transporter in neutrophils.
Volume: 81
Issue: 4
Pages: 974-82
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Publication
8699821 | J:31616
First Author: Swank RT
Year: 1996
Journal: Lab Anim Sci
Title: Inherited prolonged bleeding time and platelet storage pool deficiency in the subtle gray (sut) mouse.
Volume: 46
Issue: 1
Pages: 56-60
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Publication
25036707 | J:215616
First Author: Soria FN
Year: 2014
Journal: J Clin Invest
Title: Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage.
Volume: 124
Issue: 8
Pages: 3645-55
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Publication
17963724 | J:128443
First Author: Liu RR
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Differential regulation of cell proliferation in neurogenic zones in mice lacking cystine transport by xCT.
Volume: 364
Issue: 3
Pages: 528-33
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Publication
34108554 | J:323696
First Author: Sprimont L
Year: 2021
Journal: Sci Rep
Title: Cystine-glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice.
Volume: 11
Issue: 1
Pages: 12227
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Publication
38715127 | J:348092
First Author: Beckers P
Year: 2024
Journal: J Neuroinflammation
Title: Implication of system x(c)(-) in neuroinflammation during the onset and maintenance of neuropathic pain.
Volume: 21
Issue: 1
Pages: 117
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Publication
21191088 | J:170726
First Author: Massie A
Year: 2011
Journal: FASEB J
Title: Dopaminergic neurons of system x(c)?-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
Volume: 25
Issue: 4
Pages: 1359-69
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Publication
31071489 | J:295231
First Author: Meyer AR
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury.
Volume: 8
Issue: 3
Pages: 379-405
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Publication
29079265 | J:260963
First Author: Lee J
Year: 2017
Journal: Exp Cell Res
Title: The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.
Volume: 361
Issue: 1
Pages: 178-191
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Publication
21490221 | J:170967
First Author: De Bundel D
Year: 2011
Journal: J Neurosci
Title: Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.
Volume: 31
Issue: 15
Pages: 5792-803
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Publication
28086920 | J:272775
First Author: Merckx E
Year: 2017
Journal: J Neuroinflammation
Title: Absence of system x(c)(-) on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.
Volume: 14
Issue: 1
Pages: 9
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Publication
34156426 | J:331134
First Author: Martis RM
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice.
Volume: 62
Issue: 7
Pages: 23
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Publication
27129162 | J:311045
First Author: Cai Y
Year: 2016
Journal: Oncotarget
Title: xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation.
Volume: 7
Issue: 21
Pages: 31001-13
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Publication
19695216 | J:154328
First Author: Shibasaki T
Year: 2009
Journal: Arch Biochem Biophys
Title: Aggravation of ischemia-reperfusion-triggered acute renal failure in xCT-deficient mice.
Volume: 490
Issue: 1
Pages: 63-9
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Publication
20308543 | J:159323
First Author: Nabeyama A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: xCT deficiency accelerates chemically induced tumorigenesis.
Volume: 107
Issue: 14
Pages: 6436-41
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Publication
15326101 | J:135136
First Author: Bridges CC
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: Induction of cystine-glutamate transporter xc- by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium.
Volume: 45
Issue: 9
Pages: 2906-14
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Publication
23161574 | J:194688
First Author: Balza E
Year: 2013
Journal: Carcinogenesis
Title: The pharmacologic inhibition of the xc- antioxidant system improves the antitumor efficacy of COX inhibitors in the in vivo model of 3-MCA tumorigenesis.
Volume: 34
Issue: 3
Pages: 620-6
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Publication
31019077 | J:275807
First Author: Arensman MD
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity.
Volume: 116
Issue: 19
Pages: 9533-9542
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GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7538885
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7538885
Age: postnatal week 3-6
Specimen Label: KO
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:7538890
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:7538890
Age: postnatal week 3-6
Specimen Label: KO
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7538891
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7538891
Age: postnatal week 3-6
Specimen Label: KO
Detected: false
Specimen Num: 3
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•
GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7538892
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Probe: MGI:7536948
Assay Type: RT-PCR
Annotation Date: 2023-10-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7538892
Age: postnatal week 3-6
Specimen Label: KO
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7536962
Assay Type: Western blot
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:7538967
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7536962
Assay Type: Western blot
Annotation Date: 2023-10-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:7538967
Age: postnatal week 3-6
Specimen Label: KO
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7536962
Assay Type: Western blot
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7538970
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7536962
Assay Type: Western blot
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7538970
Age: postnatal week 3-6
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7536962
Assay Type: Western blot
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7538976
Age: postnatal week 3-6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7536962
Assay Type: Western blot
Annotation Date: 2023-10-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7538976
Age: postnatal week 3-6
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:8264922
Assay Type: RT-PCR
Annotation Date: 2025-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:8264946
Age: embryonic day 14.5
Image: S2
Specimen Label: Ctrl
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:8264922
Assay Type: RT-PCR
Annotation Date: 2025-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:8264946
Age: embryonic day 14.5
Image: S2
Specimen Label: CKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_09
Specimen Label: euxassay_012149_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_10
Specimen Label: euxassay_012149_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_11
Specimen Label: euxassay_012149_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_12
Specimen Label: euxassay_012149_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_17
Specimen Label: euxassay_012149_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_18
Specimen Label: euxassay_012149_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4424011
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828273
Age: embryonic day 14.5
Image: euxassay_012149_19
Specimen Label: euxassay_012149_19
Detected: true
Specimen Num: 19
•
•
•
•
•




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