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Search results 1 to 63 out of 63 for Slfn14

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Hits by Category

Hits by Strain

Type Details Score
Gene
342618 | SLFN14
Type: gene
Organism: human
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Gene
491140 | SLFN14
Type: gene
Organism: dog, domestic
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Gene
454586 | SLFN14
Type: gene
Organism: chimpanzee
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Gene
287569 | Slfn14
Type: gene
Organism: rat
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Gene
523379 | SLFN14
Type: gene
Organism: cattle
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Gene
718850 | SLFN14
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2684866 | Slfn14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029677 | SLFN14
Type: Family
Description: The Schlafen (SLFN) family includes several mouse and human member genes that have been implicated in important functions, such as the control of cell proliferation, induction of immune responses, and the regulation of viral replication [, , , ]. Mouse and human SLFN proteins are regulated by interferons (IFNs) []. All SLFNs contain an unique Slfn box. SLFN family is comprised of 3 groups, based on the size of the encoded proteins [, , , ]:Group1: Slfn1, Slfn2, and Slfn Like 1.Group2: Slfn3, Slfn4 and Slfn12.Group3: Slfn5, Slfn8-11, Slfn13 and Slfn14.Comparing to group1 proteins, group2 and 3 proteins contain an extra SWADL domain C terminus to the AAA domain. Group3 proteins also possess a large extension C terminus to their SWADL domain. This C-terminal extension is homologous to the superfamily I of DNA/RNA helicases []. It has been proposed that the divergent AAA ATPase domain may function as an RNA-binding domain []. This entry represents Slfn14. Its function is not clear.
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Publication
25996083 | J:228099
First Author: Pisareva VP
Year: 2015
Journal: Biochemistry
Title: Characterization of Novel Ribosome-Associated Endoribonuclease SLFN14 from Rabbit Reticulocytes.
Volume: 54
Issue: 21
Pages: 3286-301
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Protein
V9GXG1
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Publication
19619625 | J:152085
First Author: Bustos O
Year: 2009
Journal: Gene
Title: Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence.
Volume: 447
Issue: 1
Pages: 1-11
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Publication
33496736 | J:325381
First Author: Stapley RJ
Year: 2021
Journal: Blood Adv
Title: Heterozygous mutation SLFN14 K208N in mice mediates species-specific differences in platelet and erythroid lineage commitment.
Volume: 5
Issue: 2
Pages: 377-390
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Publication
15351786 | J:93660
First Author: Geserick P
Year: 2004
Journal: Int Immunol
Title: Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.
Volume: 16
Issue: 10
Pages: 1535-48
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Protein
A0A1G5SL81
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: false
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Protein
A0A1G5SK54
Organism: Mus musculus/domesticus
Length: 898  
Fragment?: false
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Protein
A0A1G5SK34
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Publication
23570387 | -
First Author: Mavrommatis E
Year: 2013
Journal: J Interferon Cytokine Res
Title: The schlafen family of proteins and their regulation by interferons.
Volume: 33
Issue: 4
Pages: 206-10
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Publication
18355440 | J:134155
First Author: Neumann B
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Subcellular localization of the Schlafen protein family.
Volume: 370
Issue: 1
Pages: 62-6
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Publication
34707099 | -
First Author: Chen J
Year: 2021
Journal: Nat Commun
Title: Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells.
Volume: 12
Issue: 1
Pages: 6204
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Publication
34272366 | -
First Author: Garvie CW
Year: 2021
Journal: Nat Commun
Title: Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Volume: 12
Issue: 1
Pages: 4375
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Publication
28460425 | -
First Author: Liu F
Year: 2018
Journal: Cell Biol Int
Title: The Schlafen family: complex roles in different cell types and virus replication.
Volume: 42
Issue: 1
Pages: 2-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0016869 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018780 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2684866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018665 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017921 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018000 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017713 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:322048
     
First Author: The Centre for Phenogenomics
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission for The Centre for Phenogenomics Alleles.
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein SLFN14
Type: chain
End: 899
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Component
Component
Name: C-terminally truncated SLFN14 endoribonuclease
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UniProt Feature
UniProt Feature
 
Begin: 1
Description: C-terminally truncated SLFN14 endoribonuclease
Type: chain
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DO Term
DOID:0111055 | platelet-type bleeding disorder 20
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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